β′-Hydroxy-α,β-unsaturated ketones: A new pharmacophore for the design of anticancer drugs. Part 2

ChemMedChem

Volumn 3, Issue 11, 2008, Pages 1740-1747

  León, Leticia G ^a,b   Carballo, Rubén M ^a   Vega Hernández, María C ^a,c   Miranda, Pedro O ^a   Martín, Víctor S ^a   Padrón, Juan I ^a,d   Padrón, José M ^a,b  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

^b Madrid Spain   (Spain)

^c HOSPITAL UNIVERSITARIO DE CANARIAS   (Spain)

^d INSTITUTO DE PRODUCTOS NATURALES Y AGROBIOLOGÍA   (Spain)

Author keywords

Antitumor agents; Apoptosis; Cell cycle; Iron(III) chloride; Structure activity relationships

Indexed keywords

ALKENE; ANTINEOPLASTIC AGENT; FERRIC CHLORIDE; FERRIC ION; KETONE; LIPOCORTIN 5;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CHEMICAL MODEL; CHEMISTRY; DOSE RESPONSE; DRUG DESIGN; DRUG EFFECT; DRUG SCREENING; HUMAN; METHODOLOGY; SYNTHESIS; TUMOR CELL LINE;

ALKENES; ANNEXIN A5; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; FERRIC COMPOUNDS; HUMANS; KETONES; MODELS, CHEMICAL;

EID: 55949109094     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200800212     Document Type: Article

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