-
1
-
-
52449132322
-
Is there a code embedded in proteins that is based on post-translational modifications?
-
Sims R.J., Reinberg D. Is there a code embedded in proteins that is based on post-translational modifications?. Nat. Rev. Mol. Cell. Biol. 2008, 9:815-820.
-
(2008)
Nat. Rev. Mol. Cell. Biol.
, vol.9
, pp. 815-820
-
-
Sims, R.J.1
Reinberg, D.2
-
2
-
-
28044433451
-
Protein posttranslational modifications: the chemistry of proteome diversifications
-
Walsh C.T., Garneau-Tsodikova S., Gatto G.J. Protein posttranslational modifications: the chemistry of proteome diversifications. Angew. Chem. Int. Ed. Engl. 2005, 44:7342-7372.
-
(2005)
Angew. Chem. Int. Ed. Engl.
, vol.44
, pp. 7342-7372
-
-
Walsh, C.T.1
Garneau-Tsodikova, S.2
Gatto, G.J.3
-
3
-
-
35848970747
-
Mapping protein post-translational modifications with mass spectrometry
-
Witze E.S., Old W.M., Resing K.A., Ahn N.G. Mapping protein post-translational modifications with mass spectrometry. Nat. Methods 2007, 4:798-806.
-
(2007)
Nat. Methods
, vol.4
, pp. 798-806
-
-
Witze, E.S.1
Old, W.M.2
Resing, K.A.3
Ahn, N.G.4
-
4
-
-
39749099462
-
Strategy for comprehensive identification of post-translational modifications in cellular proteins, including low abundant modifications: application to glyceraldehyde-3-phosphate dehydrogenase
-
Seo J., Jeong J., Kim Y.M., Hwang N., Paek E., Lee K.J. Strategy for comprehensive identification of post-translational modifications in cellular proteins, including low abundant modifications: application to glyceraldehyde-3-phosphate dehydrogenase. J. Proteome Res. 2008, 7:587-602.
-
(2008)
J. Proteome Res.
, vol.7
, pp. 587-602
-
-
Seo, J.1
Jeong, J.2
Kim, Y.M.3
Hwang, N.4
Paek, E.5
Lee, K.J.6
-
5
-
-
5644247544
-
Strategies for shotgun identification of post-translational modifications by mass spectrometry
-
Cantin G.T., Yates J.R. Strategies for shotgun identification of post-translational modifications by mass spectrometry. J. Chromatogr. A 2004, 1053:7-14.
-
(2004)
J. Chromatogr. A
, vol.1053
, pp. 7-14
-
-
Cantin, G.T.1
Yates, J.R.2
-
6
-
-
71549136813
-
Identification and quantification of protein posttranslational modifications
-
Farley A.R., Link A.J. Identification and quantification of protein posttranslational modifications. Methods Enzymol. 2009, 463:725-763.
-
(2009)
Methods Enzymol.
, vol.463
, pp. 725-763
-
-
Farley, A.R.1
Link, A.J.2
-
7
-
-
0012473279
-
The nuclear receptor superfamily: the second decade
-
Mangelsdorf D.J., Thummel C., Beato M., Herrlich P., Schutz G., Umesono K., Blumberg B., Kastner P., Mark M., Chambon P., Evans R.M. The nuclear receptor superfamily: the second decade. Cell 1995, 83:835-839.
-
(1995)
Cell
, vol.83
, pp. 835-839
-
-
Mangelsdorf, D.J.1
Thummel, C.2
Beato, M.3
Herrlich, P.4
Schutz, G.5
Umesono, K.6
Blumberg, B.7
Kastner, P.8
Mark, M.9
Chambon, P.10
Evans, R.M.11
-
8
-
-
0033305499
-
Orphan nuclear receptors: from gene to function
-
Giguere V. Orphan nuclear receptors: from gene to function. Endocr. Rev. 1999, 20:689-725.
-
(1999)
Endocr. Rev.
, vol.20
, pp. 689-725
-
-
Giguere, V.1
-
9
-
-
42249106086
-
Regulation of hepatocyte nuclear factor 4 alpha-mediated transcription
-
Gonzalez F.J. Regulation of hepatocyte nuclear factor 4 alpha-mediated transcription. Drug Metab. Pharmacokinet. 2008, 23:2-7.
-
(2008)
Drug Metab. Pharmacokinet.
, vol.23
, pp. 2-7
-
-
Gonzalez, F.J.1
-
10
-
-
10544236911
-
Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)
-
Yamagata K., Furuta H., Oda N., Kaisaki P.J., Menzel S., Cox N.J., Fajans S.S., Signorini S., Stoffel M., Bell G.I. Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1). Nature 1996, 384:458-460.
-
(1996)
Nature
, vol.384
, pp. 458-460
-
-
Yamagata, K.1
Furuta, H.2
Oda, N.3
Kaisaki, P.J.4
Menzel, S.5
Cox, N.J.6
Fajans, S.S.7
Signorini, S.8
Stoffel, M.9
Bell, G.I.10
-
11
-
-
33748357551
-
Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha (HNF1A) and 4 alpha (HNF4A) in maturity-onset diabetes of the young
-
Ellard S., Colclough K. Mutations in the genes encoding the transcription factors hepatocyte nuclear factor 1 alpha (HNF1A) and 4 alpha (HNF4A) in maturity-onset diabetes of the young. Hum. Mutat. 2006, 27:854-869.
-
(2006)
Hum. Mutat.
, vol.27
, pp. 854-869
-
-
Ellard, S.1
Colclough, K.2
-
12
-
-
0025690311
-
Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
-
Sladek F.M., Zhong W.M., Lai E., Darnell J.E. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev. 1990, 4:2353-2365.
-
(1990)
Genes Dev.
, vol.4
, pp. 2353-2365
-
-
Sladek, F.M.1
Zhong, W.M.2
Lai, E.3
Darnell, J.E.4
-
13
-
-
0028886694
-
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase
-
Kato S., Endoh H., Masuhiro Y., Kitamoto T., Uchiyama S., Sasaki H., Masushige S., Gotoh Y., Nishida E., Kawashima H., Metzger D., Chambon P. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 1995, 270:1491-1494.
-
(1995)
Science
, vol.270
, pp. 1491-1494
-
-
Kato, S.1
Endoh, H.2
Masuhiro, Y.3
Kitamoto, T.4
Uchiyama, S.5
Sasaki, H.6
Masushige, S.7
Gotoh, Y.8
Nishida, E.9
Kawashima, H.10
Metzger, D.11
Chambon, P.12
-
14
-
-
0031054568
-
Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of HNF-4(-/-) embryos
-
Duncan S.A., Nagy A., Chan W. Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: tetraploid rescue of HNF-4(-/-) embryos. Development 1997, 124:279-287.
-
(1997)
Development
, vol.124
, pp. 279-287
-
-
Duncan, S.A.1
Nagy, A.2
Chan, W.3
-
15
-
-
0035141324
-
Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
-
Hayhurst G.P., Lee Y.H., Lambert G., Ward J.M., Gonzalez F.J. Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol. Cell. Biol. 2001, 21:1393-1403.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1393-1403
-
-
Hayhurst, G.P.1
Lee, Y.H.2
Lambert, G.3
Ward, J.M.4
Gonzalez, F.J.5
-
16
-
-
1842478960
-
Identification of a liver-specific uridine phosphorylase that is regulated by multiple lipid-sensing nuclear receptors
-
Zhang Y., Repa J.J., Inoue Y., Hayhurst G.P., Gonzalez F.J., Mangelsdorf D.J. Identification of a liver-specific uridine phosphorylase that is regulated by multiple lipid-sensing nuclear receptors. Mol. Endocrinol. 2004, 18:851-862.
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 851-862
-
-
Zhang, Y.1
Repa, J.J.2
Inoue, Y.3
Hayhurst, G.P.4
Gonzalez, F.J.5
Mangelsdorf, D.J.6
-
17
-
-
0037067687
-
Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4alpha (HNF4α). HNF4α regulates ornithine transcarbamylase in vivo
-
Inoue Y., Hayhurst G.P., Inoue J., Mori M., Gonzalez F.J. Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4alpha (HNF4α). HNF4α regulates ornithine transcarbamylase in vivo. J. Biol. Chem. 2002, 277:25257-25265.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25257-25265
-
-
Inoue, Y.1
Hayhurst, G.P.2
Inoue, J.3
Mori, M.4
Gonzalez, F.J.5
-
18
-
-
33646196920
-
Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells
-
Miura A., Yamagata K., Kakei M., Hatakeyama H., Takahashi N., Fukui K., Nammo T., Yoneda K., Inoue Y., Sladek F.M., Magnuson M.A., Kasai H., Miyagawa J., Gonzalez F.J., Shimomura I. Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells. J. Biol. Chem. 2006, 281:5246-5257.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 5246-5257
-
-
Miura, A.1
Yamagata, K.2
Kakei, M.3
Hatakeyama, H.4
Takahashi, N.5
Fukui, K.6
Nammo, T.7
Yoneda, K.8
Inoue, Y.9
Sladek, F.M.10
Magnuson, M.A.11
Kasai, H.12
Miyagawa, J.13
Gonzalez, F.J.14
Shimomura, I.15
-
19
-
-
60649099790
-
Drosophila HNF4 regulates lipid mobilization and beta-oxidation
-
Palanker L., Tennessen J.M., Lam G., Thummel C.S. Drosophila HNF4 regulates lipid mobilization and beta-oxidation. Cell. Metab. 2009, 9:228-239.
-
(2009)
Cell. Metab.
, vol.9
, pp. 228-239
-
-
Palanker, L.1
Tennessen, J.M.2
Lam, G.3
Thummel, C.S.4
-
20
-
-
79957906726
-
PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B.
-
Nat. Cell. Biol.
-
A. Baba, F. Ohtake, Y. Okuno, K. Yokota, M. Okada, Y. Imai, M. Ni, C.A. Meyer, K. Igarashi, J. Kanno, M. Brown, S. Kato, PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B. Nat. Cell. Biol. (2011).
-
(2011)
-
-
Baba, A.1
Ohtake, F.2
Okuno, Y.3
Yokota, K.4
Okada, M.5
Imai, Y.6
Ni, M.7
Meyer, C.A.8
Igarashi, K.9
Kanno, J.10
Brown, M.11
Kato, S.12
-
21
-
-
67349189942
-
GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis
-
Fujiki R., Chikanishi T., Hashiba W., Ito H., Takada I., Roeder R.G., Kitagawa H., Kato S. GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis. Nature 2009, 459:455-459.
-
(2009)
Nature
, vol.459
, pp. 455-459
-
-
Fujiki, R.1
Chikanishi, T.2
Hashiba, W.3
Ito, H.4
Takada, I.5
Roeder, R.G.6
Kitagawa, H.7
Kato, S.8
-
22
-
-
70350044885
-
DNA demethylation in hormone-induced transcriptional derepression
-
Kim M.S., Kondo T., Takada I., Youn M.Y., Yamamoto Y., Takahashi S., Matsumoto T., Fujiyama S., Shirode Y., Yamaoka I., Kitagawa H., Takeyama K., Shibuya H., Ohtake F., Kato S. DNA demethylation in hormone-induced transcriptional derepression. Nature 2009, 461:1007-1012.
-
(2009)
Nature
, vol.461
, pp. 1007-1012
-
-
Kim, M.S.1
Kondo, T.2
Takada, I.3
Youn, M.Y.4
Yamamoto, Y.5
Takahashi, S.6
Matsumoto, T.7
Fujiyama, S.8
Shirode, Y.9
Yamaoka, I.10
Kitagawa, H.11
Takeyama, K.12
Shibuya, H.13
Ohtake, F.14
Kato, S.15
-
23
-
-
0031590813
-
Functional association between CBP and HNF4 in trans-activation
-
Yoshida E., Aratani S., Itou H., Miyagishi M., Takiguchi M., Osumu T., Murakami K., Fukamizu A. Functional association between CBP and HNF4 in trans-activation. Biochem. Biophys. Res. Commun. 1997, 241:664-669.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.241
, pp. 664-669
-
-
Yoshida, E.1
Aratani, S.2
Itou, H.3
Miyagishi, M.4
Takiguchi, M.5
Osumu, T.6
Murakami, K.7
Fukamizu, A.8
-
24
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers J.T., Lerin C., Haas W., Gygi S.P., Spiegelman B.M., Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 2005, 434:113-118.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
25
-
-
77954722645
-
KIAA1718 is a histone demethylase that erases repressive histone methyl marks
-
Yokoyama A., Okuno Y., Chikanishi T., Hashiba W., Sekine H., Fujiki R., Kato S. KIAA1718 is a histone demethylase that erases repressive histone methyl marks. Genes Cells 2010, 15:867-873.
-
(2010)
Genes Cells
, vol.15
, pp. 867-873
-
-
Yokoyama, A.1
Okuno, Y.2
Chikanishi, T.3
Hashiba, W.4
Sekine, H.5
Fujiki, R.6
Kato, S.7
-
26
-
-
33749238368
-
Gaining knowledge from previously unexplained spectra-application of the PTM-Explorer software to detect PTM in HUPO BPP MS/MS data
-
Chamrad D.C., Korting G., Schafer H., Stephan C., Thiele H., Apweiler R., Meyer H.E., Marcus K., Bluggel M. Gaining knowledge from previously unexplained spectra-application of the PTM-Explorer software to detect PTM in HUPO BPP MS/MS data. Proteomics 2006, 6:5048-5058.
-
(2006)
Proteomics
, vol.6
, pp. 5048-5058
-
-
Chamrad, D.C.1
Korting, G.2
Schafer, H.3
Stephan, C.4
Thiele, H.5
Apweiler, R.6
Meyer, H.E.7
Marcus, K.8
Bluggel, M.9
-
27
-
-
77149158441
-
Unrestricted identification of modified proteins using MS/MS
-
Ahrne E., Muller M., Lisacek F. Unrestricted identification of modified proteins using MS/MS. Proteomics 2010, 10:671-686.
-
(2010)
Proteomics
, vol.10
, pp. 671-686
-
-
Ahrne, E.1
Muller, M.2
Lisacek, F.3
-
28
-
-
0030877342
-
Protein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4
-
Viollet B., Kahn A., Raymondjean M. Protein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4. Mol. Cell. Biol. 1997, 17:4208-4219.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4208-4219
-
-
Viollet, B.1
Kahn, A.2
Raymondjean, M.3
-
29
-
-
78650950537
-
Proteomic analysis of native hepatocyte nuclear factor-4alpha (HNF4α) isoforms, phosphorylation status, and interactive cofactors
-
Daigo K., Kawamura T., Ohta Y., Ohashi R., Katayose S., Tanaka T., Aburatani H., Naito M., Kodama T., Ihara S., Hamakubo T. Proteomic analysis of native hepatocyte nuclear factor-4alpha (HNF4α) isoforms, phosphorylation status, and interactive cofactors. J. Biol. Chem. 2011, 286:674-686.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 674-686
-
-
Daigo, K.1
Kawamura, T.2
Ohta, Y.3
Ohashi, R.4
Katayose, S.5
Tanaka, T.6
Aburatani, H.7
Naito, M.8
Kodama, T.9
Ihara, S.10
Hamakubo, T.11
-
30
-
-
0033636892
-
Acetylation regulates transcription factor activity at multiple levels
-
Soutoglou E., Katrakili N., Talianidis I. Acetylation regulates transcription factor activity at multiple levels. Mol. Cell. 2000, 5:745-751.
-
(2000)
Mol. Cell.
, vol.5
, pp. 745-751
-
-
Soutoglou, E.1
Katrakili, N.2
Talianidis, I.3
-
31
-
-
0242349197
-
Regulation of hepatic fasting response by PPARγ coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4α in gluconeogenesis
-
Rhee J., Inoue Y., Yoon J.C., Puigserver P., Fan M., Gonzalez F.J., Spiegelman B.M. Regulation of hepatic fasting response by PPARγ coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4α in gluconeogenesis. Proc. Natl. Acad. Sci. USA 2003, 100:4012-4017.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4012-4017
-
-
Rhee, J.1
Inoue, Y.2
Yoon, J.C.3
Puigserver, P.4
Fan, M.5
Gonzalez, F.J.6
Spiegelman, B.M.7
-
32
-
-
0035855858
-
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
-
Yoon J.C., Puigserver P., Chen G., Donovan J., Wu Z., Rhee J., Adelmant G., Stafford J., Kahn C.R., Granner D.K., Newgard C.B., Spiegelman B.M. Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 2001, 413:131-138.
-
(2001)
Nature
, vol.413
, pp. 131-138
-
-
Yoon, J.C.1
Puigserver, P.2
Chen, G.3
Donovan, J.4
Wu, Z.5
Rhee, J.6
Adelmant, G.7
Stafford, J.8
Kahn, C.R.9
Granner, D.K.10
Newgard, C.B.11
Spiegelman, B.M.12
-
33
-
-
0032850195
-
Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4α1
-
Sladek F.M., Ruse M.D., Nepomuceno L., Huang S.M., Stallcup M.R. Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4α1. Mol. Cell. Biol. 1999, 19:6509-6522.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6509-6522
-
-
Sladek, F.M.1
Ruse, M.D.2
Nepomuceno, L.3
Huang, S.M.4
Stallcup, M.R.5
-
34
-
-
20444475700
-
Role of regulatory F-domain in hepatocyte nuclear factor 4α ligand specificity
-
Petrescu A.D., Hertz R., Bar-Tana J., Schroeder F., Kier A.B. Role of regulatory F-domain in hepatocyte nuclear factor 4α ligand specificity. J. Biol. Chem. 2005, 280:16714-16727.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16714-16727
-
-
Petrescu, A.D.1
Hertz, R.2
Bar-Tana, J.3
Schroeder, F.4
Kier, A.B.5
-
35
-
-
0031017027
-
Functional domains of the nuclear receptor hepatocyte nuclear factor 4
-
Hadzopoulou-Cladaras M., Kistanova E., Evagelopoulou C., Zeng S., Cladaras C., Ladias J.A. Functional domains of the nuclear receptor hepatocyte nuclear factor 4. J. Biol. Chem. 1997, 272:539-550.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 539-550
-
-
Hadzopoulou-Cladaras, M.1
Kistanova, E.2
Evagelopoulou, C.3
Zeng, S.4
Cladaras, C.5
Ladias, J.A.6
-
36
-
-
0032077536
-
The activation function 2 domain of hepatic nuclear factor 4 is regulated by a short C-terminal proline-rich repressor domain
-
Iyemere V.P., Davies N.H., Brownlee G.G. The activation function 2 domain of hepatic nuclear factor 4 is regulated by a short C-terminal proline-rich repressor domain. Nucleic Acids Res. 1998, 26:2098-2104.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 2098-2104
-
-
Iyemere, V.P.1
Davies, N.H.2
Brownlee, G.G.3
|