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Volumn 55, Issue 8, 2011, Pages 3774-3781

New Fks hot spot for acquired echinocandin resistance in Saccharomyces cerevisiae and its contribution to intrinsic resistance of Scedosporium species

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BETA GLUCAN SYNTHASE; ANIDULAFUNGIN; CASPOFUNGIN; MEMBRANE PROTEIN; MICAFUNGIN; PROTEIN FKS1; PROTEIN FKS2; UNCLASSIFIED DRUG;

EID: 79960329629     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01811-10     Document Type: Article
Times cited : (72)

References (36)
  • 1
    • 65349126661 scopus 로고    scopus 로고
    • Daptomycin: Mechanisms of action and resistance, and biosynthetic engineering
    • Baltz, R. H. 2009. Daptomycin: mechanisms of action and resistance, and biosynthetic engineering. Curr. Opin. Chem. Biol. 13:144-151.
    • (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 144-151
    • Baltz, R.H.1
  • 2
    • 77952648499 scopus 로고    scopus 로고
    • Low prevalence of fks1 hot spot 1 mutations in a worldwide collection of Candida strains
    • Castanheira, M., et al. 2010. Low prevalence of fks1 hot spot 1 mutations in a worldwide collection of Candida strains. Antimicrob. Agents Chemother. 54:2655-2659.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 2655-2659
    • Castanheira, M.1
  • 3
    • 50649101461 scopus 로고    scopus 로고
    • Aspergillus to zygomycetes: Causes, risk factors, prevention, and treatment of invasive fungal infections
    • Cornely, O. 2008. Aspergillus to zygomycetes: causes, risk factors, prevention, and treatment of invasive fungal infections. Infection 36:296-313.
    • (2008) Infection , vol.36 , pp. 296-313
    • Cornely, O.1
  • 4
    • 38549155532 scopus 로고    scopus 로고
    • Infections caused by Scedosporium spp
    • Cortez, K. J., et al. 2008. Infections caused by Scedosporium spp. Clin. Microbiol. Rev. 21:157-197.
    • (2008) Clin. Microbiol. Rev. , vol.21 , pp. 157-197
    • Cortez, K.J.1
  • 5
    • 66149156191 scopus 로고    scopus 로고
    • Activity profile in vitro of micafungin against Spanish clinical isolates of common and emerging species of yeasts and molds
    • Cuenca-Estrella, M., et al. 2009. Activity profile in vitro of micafungin against Spanish clinical isolates of common and emerging species of yeasts and molds. Antimicrob. Agents Chemother. 53:2192-2195.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 2192-2195
    • Cuenca-Estrella, M.1
  • 6
    • 0141863188 scopus 로고    scopus 로고
    • Echinocandin antifungal drugs
    • DOI 10.1016/S0140-6736(03)14472-8
    • Denning, D. W. 2003. Echinocandin antifungal drugs. Lancet 362:1142-1151. (Pubitemid 37222342)
    • (2003) Lancet , vol.362 , Issue.9390 , pp. 1142-1151
    • Denning, D.W.1
  • 7
    • 0035668391 scopus 로고    scopus 로고
    • Fungal β-(1,3)-D-glucan synthesis
    • Douglas, C. M. 2001. Fungal β-(1,3)-D-glucan synthesis. Med. Mycol. 39(Suppl. 1):55-66.
    • (2001) Med. Mycol. , vol.39 , Issue.SUPPL. 1 , pp. 55-66
    • Douglas, C.M.1
  • 8
    • 2642586332 scopus 로고    scopus 로고
    • In vitro antifungal activities of anidulafungin and micafungin, licensed agents and the investigational triazole posaconazole as determined by NCCLS methods for 12,052 fungal isolates: Review of the literature
    • Espinel-Ingroff, A. 2003. In vitro antifungal activities of anidulafungin and micafungin, licensed agents and the investigational triazole posaconazole as determined by NCCLS methods for 12,052 fungal isolates: review of the literature. Rev. Iberoam. Micol. 20:121-136.
    • (2003) Rev. Iberoam. Micol. , vol.20 , pp. 121-136
    • Espinel-Ingroff, A.1
  • 9
    • 59249085257 scopus 로고    scopus 로고
    • Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence
    • Ferrari, S., et al. 2009. Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence. PLoS Pathog. 5:1-17.
    • (2009) PLoS Pathog. , vol.5 , pp. 1-17
    • Ferrari, S.1
  • 10
    • 46249106060 scopus 로고    scopus 로고
    • A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility
    • Garcia-Effron, G., S. K. Katiyar, S. Park, T. D. Edlind, and D. S. Perlin. 2008. A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility. Antimicrob. Agents Chemother. 52:2305-2312.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 2305-2312
    • Garcia-Effron, G.1    Katiyar, S.K.2    Park, S.3    Edlind, T.D.4    Perlin, D.S.5
  • 11
    • 70349127708 scopus 로고    scopus 로고
    • Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-β-D-glucan synthase: Implication for the existing susceptibility breakpoint
    • Garcia-Effron, G., S. Lee, S. Park, J. D. Cleary, and D. S. Perlin. 2009. Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-β-D-glucan synthase: implication for the existing susceptibility breakpoint. Antimicrob. Agents Chemother. 53:3690-3699.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 3690-3699
    • Garcia-Effron, G.1    Lee, S.2    Park, S.3    Cleary, J.D.4    Perlin, D.S.5
  • 12
    • 0035747143 scopus 로고    scopus 로고
    • Uncommon opportunistic fungi: New nosocomial threats
    • Groll, A. H., and T. J. Walsh. 2001. Uncommon opportunistic fungi: new nosocomial threats. Clin. Microbiol. Infect. 7:8-24.
    • (2001) Clin. Microbiol. Infect. , vol.7 , pp. 8-24
    • Groll, A.H.1    Walsh, T.J.2
  • 13
    • 0141924879 scopus 로고    scopus 로고
    • Cyclic AMP signaling pathway modulates susceptibility of Candida species and Saccharomyces cerevisiae to antifungal azoles and other sterol biosynthesis inhibitors
    • Jain, P., I. Akula, and T. Edlind. 2003. Cyclic AMP signaling pathway modulates susceptibility of Candida species and Saccharomyces cerevisiae to antifungal azoles and other sterol biosynthesis inhibitors. Antimicrob. Agents Chemother. 47:3195-3201.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 3195-3201
    • Jain, P.1    Akula, I.2    Edlind, T.3
  • 14
    • 66149144294 scopus 로고    scopus 로고
    • Role for Fks1 in the intrinsic echinocandin resistance of Fusarium solani as evidenced by hybrid expression in Saccharomyces cerevisiae
    • Katiyar, S. K., and T. D. Edlind. 2009. Role for Fks1 in the intrinsic echinocandin resistance of Fusarium solani as evidenced by hybrid expression in Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 53:1772-1778.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 1772-1778
    • Katiyar, S.K.1    Edlind, T.D.2
  • 17
    • 0037197022 scopus 로고    scopus 로고
    • Antifungal drug resistance of pathogenic fungi
    • Kontoyiannis, D. P., and R. E. Lewis. 2002. Antifungal drug resistance of pathogenic fungi. Lancet 359:1135-1144.
    • (2002) Lancet , vol.359 , pp. 1135-1144
    • Kontoyiannis, D.P.1    Lewis, R.E.2
  • 18
    • 0035910270 scopus 로고    scopus 로고
    • Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes
    • Krogh, A., B. Larsson, G. von Heijne, and E. L. L. Sonnhammer. 2001. Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305:567-580.
    • (2001) J. Mol. Biol. , vol.305 , pp. 567-580
    • Krogh, A.1    Larsson, B.2    Von Heijne, G.3    Sonnhammer, E.L.L.4
  • 19
    • 0035061445 scopus 로고    scopus 로고
    • Glucan synthase inhibitors as antifungal agents
    • Kurtz, M. B., and J. H. Rex. 2001. Glucan synthase inhibitors as antifungal agents. Adv. Protein Chem. 56:423-475.
    • (2001) Adv. Protein Chem. , vol.56 , pp. 423-475
    • Kurtz, M.B.1    Rex, J.H.2
  • 20
    • 34548366493 scopus 로고    scopus 로고
    • Changing epidemiology of rare mould infections: Implications for therapy
    • Malani, A. N., and C. A. Kauffman. 2007. Changing epidemiology of rare mould infections: implications for therapy. Drugs 67:1803-1812.
    • (2007) Drugs , vol.67 , pp. 1803-1812
    • Malani, A.N.1    Kauffman, C.A.2
  • 21
    • 79952806283 scopus 로고    scopus 로고
    • Differential activities of three families of specific β(1,3)glucan synthase inhibitors in wild-type and resistant strains of fission yeast
    • Martins, I. M., et al. 2011. Differential activities of three families of specific β(1,3)glucan synthase inhibitors in wild-type and resistant strains of fission yeast. J. Biol. Chem. 286:3484-3496.
    • (2011) J. Biol. Chem. , vol.286 , pp. 3484-3496
    • Martins, I.M.1
  • 22
    • 0029128074 scopus 로고
    • Differential expression and function of two homologous subunits of yeast 1,3-β-D-glucan synthase
    • Mazur, P., et al. 1995. Differential expression and function of two homologous subunits of yeast 1,3-β-D-glucan synthase. Mol. Cell. Biol. 15:5671-5681.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5671-5681
    • Mazur, P.1
  • 23
    • 0037378071 scopus 로고    scopus 로고
    • In vitro antifungal activity of micafungin (FK463) against dimorphic fungi: Comparison of yeast-like and mycelial forms
    • Nakai, T., et al. 2003. In vitro antifungal activity of micafungin (FK463) against dimorphic fungi: comparison of yeast-like and mycelial forms. Antimicrob. Agents Chemother. 47:1376-1381.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 1376-1381
    • Nakai, T.1
  • 24
    • 35448960891 scopus 로고    scopus 로고
    • Fusarium infections in immunocompromised patients
    • Nucci, M., and E. Anaissie. 2007. Fusarium infections in immunocompromised patients. Clin. Microbiol. Rev. 20:695-704.
    • (2007) Clin. Microbiol. Rev. , vol.20 , pp. 695-704
    • Nucci, M.1    Anaissie, E.2
  • 25
    • 60549098868 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America
    • Pappas, P. G., et al. 2009. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin. Infect. Dis. 48:503-535.
    • (2009) Clin. Infect. Dis. , vol.48 , pp. 503-535
    • Pappas, P.G.1
  • 26
    • 0027787589 scopus 로고
    • Calcineurin-dependent growth of an FK506- and CsA-hypersensitive mutant of Saccharomyces cerevisiae
    • Parent, S. A., et al. 1993. Calcineurin-dependent growth of an FK506- and CsA-hypersensitive mutant of Saccharomyces cerevisiae. J. Gen. Microbiol. 139:2973-2984.
    • (1993) J. Gen. Microbiol. , vol.139 , pp. 2973-2984
    • Parent, S.A.1
  • 27
    • 34447105864 scopus 로고    scopus 로고
    • Resistance to echinocandin-class antifungal drugs
    • Perlin, D. S. 2007. Resistance to echinocandin-class antifungal drugs. Drug Res. Updat. 10:121-130.
    • (2007) Drug Res. Updat. , vol.10 , pp. 121-130
    • Perlin, D.S.1
  • 28
    • 74949107171 scopus 로고    scopus 로고
    • Epidemiology of invasive mycoses in North America
    • Pfaller, M. A., and D. J. Diekema. 2010. Epidemiology of invasive mycoses in North America. Crit. Rev. Microbiol. 36:1-53.
    • (2010) Crit. Rev. Microbiol. , vol.36 , pp. 1-53
    • Pfaller, M.A.1    Diekema, D.J.2
  • 29
    • 5444272819 scopus 로고    scopus 로고
    • Rare and emerging opportunistic fungal pathogens: Concern for resistance beyond Candida albicans and Aspergillus fumigatus
    • Pfaller, M. A., and D. J. Diekema. 2004. Rare and emerging opportunistic fungal pathogens: concern for resistance beyond Candida albicans and Aspergillus fumigatus. J. Clin. Microbiol. 42:4419-4431.
    • (2004) J. Clin. Microbiol. , vol.42 , pp. 4419-4431
    • Pfaller, M.A.1    Diekema, D.J.2
  • 30
    • 0031981860 scopus 로고    scopus 로고
    • Photoaffinity analog of the semisynthetic echinocandin LY303366: Identification of echinocandin targets in Candida albicans
    • Radding, J. A., S. A. Heidler, and W. W. Turner. 1998. Photoaffinity analog of the semisynthetic echinocandin LY303366: identification of echinocandin targets in Candida albicans. Antimicrob. Agents Chemother. 42:1187-1194.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 1187-1194
    • Radding, J.A.1    Heidler, S.A.2    Turner, W.W.3
  • 31
    • 42649102359 scopus 로고    scopus 로고
    • Changing epidemiology of systemic fungal infections
    • Richardson, M., and C. Lass-Flörl. 2008. Changing epidemiology of systemic fungal infections. Clin. Microbiol. Infect. 14:5-24.
    • (2008) Clin. Microbiol. Infect. , vol.14 , pp. 5-24
    • Richardson, M.1    Lass-Flörl, C.2
  • 32
    • 0141818929 scopus 로고    scopus 로고
    • Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery
    • Roemer, T., et al. 2003. Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery. Mol. Microbiol. 50: 167-181.
    • (2003) Mol. Microbiol. , vol.50 , pp. 167-181
    • Roemer, T.1
  • 33
    • 0031938057 scopus 로고    scopus 로고
    • Amino acid substitutions in the cytochrome P-450 lanosterol 14α-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents
    • Sanglard, D., F. Ischer, L. Koymans, and J. Bille. 1998. Amino acid substitutions in the cytochrome P-450 lanosterol 14α-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents. Antimicrob. Agents Chemother. 42:241-253.
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 241-253
    • Sanglard, D.1    Ischer, F.2    Koymans, L.3    Bille, J.4
  • 34
    • 0036488166 scopus 로고    scopus 로고
    • Resistance of Candida species to antifungal agents: Molecular mechanisms and clinical consequences
    • Sanglard, D., and F. C. Odds. 2002. Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences. Lancet Infect. Dis. 2:73-85.
    • (2002) Lancet Infect. Dis. , vol.2 , pp. 73-85
    • Sanglard, D.1    Odds, F.C.2
  • 35
    • 4644254793 scopus 로고    scopus 로고
    • Azole resistance in Candida glabrata: Coordinate upregulation of multidrug transporters and evidence for a Pdr1-Like transcription factor
    • Vermitsky, J.-P., and T. D. Edlind. 2004. Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-Like transcription factor. Antimicrob. Agents Chemother. 48:3773-3781.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 3773-3781
    • Vermitsky, J.-P.1    Edlind, T.D.2
  • 36
    • 0346784897 scopus 로고    scopus 로고
    • Three-Dimensional Models of Wild-Type and Mutated Forms of Cytochrome P450 14α-Sterol Demethylases from Aspergillus fumigatus and Candida albicans Provide Insights into Posaconazole Binding
    • DOI 10.1128/AAC.48.2.568-574.2004
    • Xiao, L., et al. 2004. Three-dimensional models of wild-type and mutated forms of cytochrome P450 14α-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding. Antimicrob. Agents Chemother. 48:568-574. (Pubitemid 38141718)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.2 , pp. 568-574
    • Xiao, L.1    Madison, V.2    Chau, A.S.3    Loebenberg, D.4    Palermo, R.E.5    McNicholas, P.M.6


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