Swim-exercised mice show a decreased level of protein O-GlcNAcylation and expression of O-GlcNAc transferase in heart

Journal of Applied Physiology

Volumn 111, Issue 1, 2011, Pages 157-162

  Belke, Darrell D ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Gene expression; O GlcNAcase; Physiological hypertrophy; Working heart

Indexed keywords

GFPT2 PROTEIN, MOUSE; MESSENGER RNA; MUSCLE PROTEIN; N ACETYLGLUCOSAMINE; N ACETYLGLUCOSAMINYLTRANSFERASE; O GLCNAC TRANSFERASE; O-GLCNAC TRANSFERASE; SERINE; THREONINE; TRANSFERASE;

ADAPTATION; ANIMAL; ARTICLE; CARDIOMEGALY; DOWN REGULATION; EXERCISE; GENE EXPRESSION REGULATION; GENETICS; GLYCOSYLATION; HEART MUSCLE; MALE; METABOLISM; MOUSE; MUSCLE CONTRACTION; PATHOPHYSIOLOGY; PROTEIN PROCESSING; SWIMMING;

ACETYLGLUCOSAMINE; ADAPTATION, PHYSIOLOGICAL; ANIMALS; CARDIOMEGALY; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCOSYLATION; MALE; MICE; MUSCLE CONTRACTION; MUSCLE PROTEINS; MYOCARDIUM; N-ACETYLGLUCOSAMINYLTRANSFERASES; NITROGENOUS GROUP TRANSFERASES; PHYSICAL EXERTION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER; SERINE; SWIMMING; THREONINE;

EID: 79960281916     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00147.2011     Document Type: Article

References (38)

1. Barger PM, Brandt JM, Leone TC, Weinheimer CJ, Kelly DP. Deactivation of peroxisome proliferator-activated receptor-α during cardiac hypertrophic growth. J Clin Invest 105:1723-1730, 2000. (Pubitemid 30421753)
2. Belke DD, Swanson E, Suarez J, Scott BT, Stenbit AE, Dillmann WH. Increased expression of SERCA in the hearts of transgenic mice results in increased oxidation of glucose. Am J Physiol Heart Circ Physiol 292:H1755-H1763, 2007. (Pubitemid 46572398)
3. Belke DD, Gloss B, Swanson EA, Dillmann WH. AAV-mediated expression of thyroid hormone receptor isoforms a1 and b1 improves contractile function in pressure overload-induced cardiac hypertrophy. Endocrinology 148:2870-7, 2007. (Pubitemid 46984823)
4. Bourajjaj M, Armand AS, da Costa Martins PA, da Costa Martins PA, Weijts B, van der Nagel R, Heeneman S, Wehrens XH, De Windt LJ. NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure. J Biol Chem 283:22295-22303, 2008.
5. Champattanachai V, Marchase RB, Chatham JC. Glucosamine protects neonatal cardiomyocytes from ischemia-reperfusion injury via increased protein-associated O-GlcNAc. Am J Physiol Cell Physiol 292:C178-C187, 2007. (Pubitemid 46115129)
6. Cooksey RC, McClain DA. Increased hexosamine pathway flux and high fat feeding are not additive in inducing insulin resistance: evidence for a shared pathway. Amino Acids 40:841-846, 2011.
7. Diedrichs H, Hagemeister J, Chi M, Boelck B, Müller-Ehmsen J, Schneider CA. Activation of the calcineurin/NFAT signalling cascade starts early in human hypertrophic myocardium. J Int Med Res 35:803-818, 2007. (Pubitemid 350238414)
8. Dolinsky VW, Dyck JR. Role of AMP-activated protein kinase in healthy and diseased hearts. Am J Physiol Heart Circ Physiol 291:H2557-H2569, 2006. (Pubitemid 44911033)
9. Dong DL, Hart GW. Purification and characterization of an O-GlcNAc selective N-acetyl-beta-D-glucosaminidase from rat spleen cytosol. J Biol Chem 269:19321-19330, 1994.
10. Flesch M. On the trail of cardiac specific transcription factors. Cardiovasc Res 50:3-6, 2001. (Pubitemid 32244379)
11. Fülöp N, Feng W, Xing D, He K, Not LG, Brocks CA, Marchase RB, Miller AP, Chatham JC. Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway rats. Biogerontology 9:139-151, 2008.
12. Gloster TM, Zandberg WF, Heinonen JE, Shen DL, Deng L, Vocadlo DJ. Hijacking a biosynthetic pathway yields a glycosyltranseferase inhibitor within cells. Nat Chem Biol 7:174-181, 2011.
13. Hu Y, Belke DD, Suarez J, Swanson E, Clark R, Hoshijima M, Dillmann WH. Adenovirus-mediated overexpression of O-GlcNAcase improves contractile function in the diabetic heart. Circ Res 96:1006-1013, 2005. (Pubitemid 40712801)
14. Issad T, Kuo M. O-GlcNAc modification of transcription factors, glucose sensing and glucotoxicity. Trends Endocrinol Metab 19:380-389, 2008.
15. Kawase Y, Hajjar RJ. The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases. Nat Clin Pract Cardiovasc Med 5:554-565, 2008.
16. 2+ ATPase function is increased by aerobic interval training. Eur J Cardiovasc Prev Rehabil 15:145-148, 2008. (Pubitemid 351507644)
17. Kim J, Wende AR, Sena S, Theobald HA, Soto J, Sloan C, Wayment BE, Litwin SE, Holzenberger M, LeRoith D, Abel 2008 ED. Insulinlike growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy. Mol Endocrinol 22:2531-2543, 2008.
18. 2+/calmodulin- dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest 119:1230-1240, 2009.
19. Marshall S, Bacote V, Traxinger RR. Discovery of a metabolic pathway mediating glucose-induced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance. J Biol Chem 266:4706-4712, 1991. (Pubitemid 21909414)
20. McClain DA, Lubas WA, Cooksey RC, Hazel M, Parker GJ, Love DC, Hanover JA. Altered glycan-dependent signaling induces insulin resistance and hyperleptinemia. Proc Natl Acad Sci USA 99:10695-10699, 2002.
21. Neubauer S. The failing heart-an engine out of fuel. N Engl J Med 356:1140-1151, 2007. (Pubitemid 46425598)
22. Ngoh GA, Hamid T, Prabhu SD, Jones SP. O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death. Am J Physiol Heart Circ Physiol 297:H1711-H1719, 2009.
23. O'Donnell N, Zachara NE, Hart GW, Marth JD. Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability. Mol Cell Biol 24:1680-1690, 2004. (Pubitemid 38167089)
24. Rexach JE, Rogers CJ, Yu SH, Tao J, Sun YE, Hsieh-Wilson LC. Quantification of O-glycosylation stoichiometry and dynamics using resolvable mass tags. Nat Chem Biol 6:645-651, 2010.
25. Rimbaud S, Sanchez H, Garnier A, Fortin D, Bigard X, Veksler V, Ventura-Clapier R. Stimulus specific changes of energy metabolism in hypertrophied heart. J Mol Cell Cardiol 46:952-959, 2009.
26. Rohrbach S, Martin A, Niemann B, Cherubini A. Enhanced myocardial vitamin C accumulation in left ventricular hypertrophy in rats is not attenuated with transition to heart failure. Eur J Heart Fail 10:226-232, 2008.
27. Shafi R, Iyer SP, Ellies LG, O'Donnell N, Marek KW, Chui D, Hart GW, Marth JD. The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny. Proc Natl Acad Sci USA 97:5735-9573, 2000.
28. Singleton KD, Wischmeyer PE. Glutamine induces heat shock protein expression via O-glycosylation and phosphorylation of HSF-1 and Sp1. JPEN J Parenter Enteral Nutr 32:371-376, 2008. (Pubitemid 351875930)
29. Somani SM, Frank S, Rybak LP. Responses of antioxidant system to acute and trained exercise in rat heart subcellular fractions. Pharmacol Biochem Behav 51:627-634, 1995.
30. Souza-Rabbo MP, Silva LF, Auzani JA, Picoral M, Khaper N, Belló-Klein A. Effects of a chronic exercise training protocol on oxidative stress and right ventricular hypertrophy in monocrotaline-treated rats. Clin Exp Pharmacol Physiol 35:944-948, 2008. (Pubitemid 351951943)
31. Taylor RP, Geisler TS, Chambers JH, McClain DA. Up-regulation of O-GlcNAc transferase with glucose deprivation in HepG2 cells is mediated by decreased hexosamine pathway flux. J Biol Chem 284:3425-3432, 2009.
32. Watson PA, Reusch JE, McCune SA, Leinwand LA, Luckey SW, Konhilas JP, Brown DA, Chicco AJ, Sparagna GC, Long CS, Moore RL. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. Am J Physiol Heart Circ Physiol 293:H246-H259, 2007. (Pubitemid 47105079)
33. Watson LJ, Facundo HT, Ngoh GA, Ameen M, Brainard RE, Lemma KM, Long BW, Prabhu SD, Xuan YT, Jones SP. O-linked β-N-acetylglucosamine transferase is indispensable in the failing heart. Proc Natl Acad Sci USA 107:17797-17802, 2010.
34. Young ME, Yan J, Razeghi P, Cooksey RC, Guthrie PH, Stepkowski SM, McClain DA, Tian R, Taegtmeyer H. Proposed regulation of gene expression by glucose in rodent heart. Gene Regul Syst Bio 1:251-262, 2007.
35. Zachara NE, Hart GW. Cell signaling, the essential role of O-GlcNAc. Biochim Biophys Acta 1761:599-617, 2006. (Pubitemid 43928866)
36. Zachara NE, O'Donnell N, Cheung WD, Mercer JJ, Marth JD, Hart GW. Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells. J Biol Chem 279:30133-30142, 2004. (Pubitemid 38937936)
37. Zeidan Q, Hart GW. The intersections between O-GlcNAcylation and phosphorylation: implications for multiple signaling pathways. Cell Sci 123:13-22, 2010.
38. Zou L, Yang S, Champattanachai V, Hu S, Chaudry IH, Marchase RB, Chatham JC. Glucosamine improves cardiac function following trauma-hemorrhage by increased protein O-GlcNAcylation and attenuation of NF-κB signaling. Am J Physiol Heart Circ Physiol 296:H515-H523, 2009.