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Volumn 90, Issue 8, 2011, Pages 887-899

Paroxysmal nocturnal hemoglobinuria (PNH): Higher sensitivity and validity in diagnosis and serial monitoring by flow cytometric analysis of reticulocytes

Author keywords

Flow cytometry; Glycosylphophatidyl inositol anchor; GPI deficiency; Immunophenotyping; Paroxysmal nocturnal hemoglobinuria; PNH; Reticulocytes

Indexed keywords

CD14 ANTIGEN; CD16 ANTIGEN; CD24 ANTIGEN; CD48 ANTIGEN; CD59 ANTIGEN; CD66B ANTIGEN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; LYMPHOCYTE ANTIGEN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; UNCLASSIFIED DRUG;

EID: 79960258077     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-011-1177-4     Document Type: Article
Times cited : (38)

References (32)
  • 1
    • 0000035046 scopus 로고
    • Paroxysmal nocturnal haemoglobinuria
    • 14024574 1:CAS:528:DyaF3sXkslWjtbw%3D
    • JV Dacie 1963 Paroxysmal nocturnal haemoglobinuria Proc R Soc Med 56 587 596 14024574 1:CAS:528:DyaF3sXkslWjtbw%3D
    • (1963) Proc R Soc Med , vol.56 , pp. 587-596
    • Dacie, J.V.1
  • 2
    • 0014832992 scopus 로고
    • Paroxysmal nocturnal hemoglobinuria: Evidence of monoclonal origin of abnormal red cells
    • 5448520 1:STN:280:DyaE3c3ls12nsA%3D%3D
    • SB Oni BO Osunkoya L Luzzatto 1970 Paroxysmal nocturnal hemoglobinuria: evidence of monoclonal origin of abnormal red cells Blood 36 145 152 5448520 1:STN:280:DyaE3c3ls12nsA%3D%3D
    • (1970) Blood , vol.36 , pp. 145-152
    • Oni, S.B.1    Osunkoya, B.O.2    Luzzatto, L.3
  • 4
    • 0037769826 scopus 로고    scopus 로고
    • The spectrum of PIG-A gene mutations in aplastic anemia/paroxysmal nocturnal hemoglobinuria (AA/PNH): A high incidence of multiple mutations and evidence of a mutational hot spot
    • DOI 10.1182/blood-2002-07-2095
    • Y Mortazavi B Merk J McIntosh JC Marsh H Schrezenmeier TR Rutherford BIOMED II Pathophysiology and Treatment of Aplastic Anaemia Study Group 2003 The spectrum of PIG-A mutations in aplastic anemia/paroxysmal nocturnal hemoglobinuria: a high incidence of multiple mutations and evidence of a mutational hot spot Blood 101 7 2833 2841 12424196 10.1182/blood-2002-07-2095 1:CAS:528:DC%2BD3sXivVWnsLw%3D (Pubitemid 36857651)
    • (2003) Blood , vol.101 , Issue.7 , pp. 2833-2841
    • Mortazavi, Y.1    Merk, B.2    McIntosh, J.3    Marsh, J.C.W.4    Schrezenmeier, H.5    Rutherford, T.R.6
  • 5
    • 0028057807 scopus 로고
    • Paroxysmal nocturnal hemoglobinuria is caused by somatic mutations in the PIG-A gene
    • 8306954 1:CAS:528:DyaK2cXhtVekur0%3D
    • M Bessler PJ Mason P Hillmen T Miyata N Yamada N Takeda L Luzzatto T Kinoshita 1994 Paroxysmal nocturnal hemoglobinuria is caused by somatic mutations in the PIG-A gene EMBO J 13 110 117 8306954 1:CAS:528: DyaK2cXhtVekur0%3D
    • (1994) EMBO J , vol.13 , pp. 110-117
    • Bessler, M.1    Mason, P.J.2    Hillmen, P.3    Miyata, T.4    Yamada, N.5    Takeda, N.6    Luzzatto, L.7    Kinoshita, T.8
  • 6
    • 0028802443 scopus 로고
    • Natural history of paroxysmal nocturnal hemoglobinuria
    • 10.1056/NEJM199511093331904 1:STN:280:DyaK28%2Fit1Wgtw%3D%3D
    • P Hillmen SM Lewis M Bessler L Luzzatto JV Dacie 1995 Natural history of paroxysmal nocturnal hemoglobinuria N Eng J 333 1253 1258 10.1056/ NEJM199511093331904 1:STN:280:DyaK28%2Fit1Wgtw%3D%3D
    • (1995) N Eng J , vol.333 , pp. 1253-1258
    • Hillmen, P.1    Lewis, S.M.2    Bessler, M.3    Luzzatto, L.4    Dacie, J.V.5
  • 7
    • 0026537310 scopus 로고
    • Two distinct patterns of glycosylphosphatidylinositol (GPI) linked protein deficiency in the red cells of patients with paroxysmal nocturnal haemoglobinuria
    • Hillmen P, Hows JM, Luzzatto L (1992) Two distinct patterns of glycosylphosphatidylinositol (GPI) linked protein deficiency in the red cells of patients with paroxysmal nocturnal haemoglobinuria. Br J Haematol 80(3):399-405
    • (1992) Br J Haematol , vol.80 , Issue.3 , pp. 399-405
    • Hillmen, P.1    Hows, J.M.2    Luzzatto, L.3
  • 9
    • 52049102464 scopus 로고    scopus 로고
    • Detailed immunophenotypic characterization of different major and minor subsets of peripheral blood cells in patients with paroxysmal nocturnal hemoglobinuria
    • 18422849 10.1111/j.1537-2995.2008.01686.x 1:CAS:528:DC%2BD1cXpt1emsL4%3D
    • PM Hernandez-Campo J Almeida MJ Acevedo ML Sanchez I Alberca B Vidriales E Martinez JR Romero A Orfao 2008 Detailed immunophenotypic characterization of different major and minor subsets of peripheral blood cells in patients with paroxysmal nocturnal hemoglobinuria Transfusion 48 1403 1414 18422849 10.1111/j.1537-2995.2008.01686.x 1:CAS:528:DC%2BD1cXpt1emsL4%3D
    • (2008) Transfusion , vol.48 , pp. 1403-1414
    • Hernandez-Campo, P.M.1    Almeida, J.2    Acevedo, M.J.3    Sanchez, M.L.4    Alberca, I.5    Vidriales, B.6    Martinez, E.7    Romero, J.R.8    Orfao, A.9
  • 11
    • 0041733202 scopus 로고    scopus 로고
    • Flow cytometric analysis of GPI-deficient cells for the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH)
    • DOI 10.1515/LabMed.2003.038
    • T Nebe J Schubert K Gutensohn H Schrezenmeier 2003 Flow cytometric analysis of GPI-deficient cells for the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) J Lab Med 27 257 265 10.1046/j.1439-0477.2003.03046.x 1:CAS:528:DC%2BD3sXnvFGru7w%3D (Pubitemid 36988427)
    • (2003) LaboratoriumsMedizin , vol.27 , Issue.7-8 , pp. 257-265
    • Nebe, C.T.1    Schubert, J.2    Gutensohn, K.3    Schrezenmeier, H.4
  • 12
    • 0034096753 scopus 로고    scopus 로고
    • Paroxysmal nocturnal haemoglobinuria: A replacement of haematopoietic tissue?
    • H Schrezenmeier A Hildebrand M Rojewski H Hacker H Heimpel A Raghavachar 2000 Paroxysmal nocturnal haemoglobinuria: a replacement of haematopoietic tissue? Acta Haematol 103 41 48 10705158 10.1159/000041003 1:STN:280: DC%2BD3c7ntVOjuw%3D%3D (Pubitemid 30150905)
    • (2000) Acta Haematologica , vol.103 , Issue.1 , pp. 41-48
    • Schrezenmeier, H.1    Hildebrand, A.2    Rojewski, M.3    Hacker, H.4    Heimpel, H.5    Raghavachar, A.6
  • 13
    • 3042789125 scopus 로고    scopus 로고
    • Natural history of paroxysmal nocturnal haemoglobinuria using modern diagnostic assays
    • DOI 10.1111/j.1365-2141.2004.04992.x
    • VM Moyo GL Mukhina ES Garrett RA Brodsky 2004 Natural history of paroxysmal nocturnal haemoglobinuria using modern diagnostic assays Br J Haematol 126 133 138 15198744 10.1111/j.1365-2141.2004.04992.x 1:CAS:528:DC%2BD2cXmtl2rtLw%3D (Pubitemid 38859494)
    • (2004) British Journal of Haematology , vol.126 , Issue.1 , pp. 133-138
    • Moyo, V.M.1    Mukhina, G.L.2    Garrett, E.S.3    Brodsky, R.A.4
  • 14
    • 34447558010 scopus 로고    scopus 로고
    • The Role of Flow Cytometry in the Diagnosis of Paroxysmal Nocturnal Hemoglobinuria in the Clinical Laboratory
    • DOI 10.1016/j.cll.2007.05.012, PII S0272271207000571, Flow Cytometry
    • SJ Richards D Barnett 2007 The role of flow cytometry in the diagnosis of PNH in the clinical laboratory Clin Lab Med 27 577 590 17658408 10.1016/j.cll.2007.05.012 (Pubitemid 47068815)
    • (2007) Clinics in Laboratory Medicine , vol.27 , Issue.3 , pp. 577-590
    • Richards, S.J.1    Barnett, D.2
  • 15
    • 0242494954 scopus 로고    scopus 로고
    • Primary prophylaxis with warfarin prevents thrombosis in paroxysmal nocturnal hemoglobinuria (PNH)
    • DOI 10.1182/blood-2003-01-0009
    • C Hall S Richards P Hillmen 2003 Primary prophylaxis with warfarin prevents thrombosis in PNH Blood 102 3587 3591 12893760 10.1182/blood-2003-01- 0009 1:CAS:528:DC%2BD3sXptVymtrc%3D (Pubitemid 37409375)
    • (2003) Blood , vol.102 , Issue.10 , pp. 3587-3591
    • Hall, C.1    Richards, S.2    Hillmen, P.3
  • 17
    • 77953366331 scopus 로고    scopus 로고
    • Eculizumab opens a new era of treatment for paroxysmal nocturnal hemoglobinuria
    • 21082989 10.1586/17474086.2.1.7 1:CAS:528:DC%2BD1MXjsFyrsbY%3D
    • H Schrezenmeier B Höchsmann 2009 Eculizumab opens a new era of treatment for paroxysmal nocturnal hemoglobinuria Expert Rev Hematol 2 1 7 16 21082989 10.1586/17474086.2.1.7 1:CAS:528:DC%2BD1MXjsFyrsbY%3D
    • (2009) Expert Rev Hematol , vol.2 , Issue.1 , pp. 7-16
    • Schrezenmeier, H.1    Höchsmann, B.2
  • 18
    • 34047221441 scopus 로고    scopus 로고
    • Recent developments in the understanding and management of paroxysmal nocturnal haemoglobinuria
    • DOI 10.1111/j.1365-2141.2007.06554.x
    • A Hill SJ Richards P Hillmen 2007 Recent developments in the understanding and management of PNH Br J Haematol 137 181 192 17408457 10.1111/j.1365-2141.2007.06554.x 1:CAS:528:DC%2BD2sXmtVGrsb0%3D (Pubitemid 46537635)
    • (2007) British Journal of Haematology , vol.137 , Issue.3 , pp. 181-192
    • Hill, A.1    Richards, S.J.2    Hillmen, P.3
  • 19
    • 27144440502 scopus 로고    scopus 로고
    • Sustained response and long-term safety of eculizumab in paroxysmal nocturnal hemoglobinuria
    • DOI 10.1182/blood-2005-02-0564
    • A Hill P Hillmen SJ Richards, et al. 2005 Sustained response and long term safety of eculizumab in PNH Blood 106 2559 2565 15985537 10.1182/blood-2005-02-0564 1:CAS:528:DC%2BD2MXhtVKqt7rE (Pubitemid 41510834)
    • (2005) Blood , vol.106 , Issue.7 , pp. 2559-2565
    • Hill, A.1    Hillmen, P.2    Richards, S.J.3    Elebute, D.4    Marsh, J.C.5    Chan, J.6    Mojcik, C.F.7    Rother, R.P.8
  • 20
    • 0028897137 scopus 로고
    • A pathogenetic link between aplastic anemia and paroxysmal nocturnal haemoglobinuria is suggested by a high frequency of aplastic anemia patients with a deficiency of phophatidylinositol glycan anchored proteins
    • 7995374 1:STN:280:DyaK2M%2FoslOhuw%3D%3D
    • H Schrezenmeier B Hertenstein B Wagner, et al. 1995 A pathogenetic link between aplastic anemia and paroxysmal nocturnal haemoglobinuria is suggested by a high frequency of aplastic anemia patients with a deficiency of phophatidylinositol glycan anchored proteins Exp Hematol 23 81 87 7995374 1:STN:280:DyaK2M%2FoslOhuw%3D%3D
    • (1995) Exp Hematol , vol.23 , pp. 81-87
    • Schrezenmeier, H.1    Hertenstein, B.2    Wagner, B.3
  • 22
    • 0029981029 scopus 로고    scopus 로고
    • The use of monoclonal antibodies and flow cytometry in the diagnosis of paroxysmal nocturnal hemoglobinuria
    • SE Hall WF Rosse 1996 The use of monoclonal antibodies and flow cytometry in the diagnosis of paroxysmal nocturnal hemoglobinuria Blood 87 5332 5340 8652849 1:CAS:528:DyaK28XjsFGitLc%3D (Pubitemid 26189877)
    • (1996) Blood , vol.87 , Issue.12 , pp. 5332-5340
    • Hall, S.E.1    Rosse, W.F.2
  • 24
    • 0013911413 scopus 로고
    • Immune lysis of normal human and paroxysmal nocturnal hemoglobinuria (PNH) red blood cells
    • 5935361 10.1172/JCI105388 1:CAS:528:DyaF28XktFCrsrw%3D
    • WF Rosse JV Dacie 1966 Immune lysis of normal human and paroxysmal nocturnal hemoglobinuria (PNH) red blood cells J Clin Invest 45 5 736 745 5935361 10.1172/JCI105388 1:CAS:528:DyaF28XktFCrsrw%3D
    • (1966) J Clin Invest , vol.45 , Issue.5 , pp. 736-745
    • Rosse, W.F.1    Dacie, J.V.2
  • 25
    • 0031948379 scopus 로고    scopus 로고
    • Investigation of the survival of paroxysmal nocturnal hemoglobinuria red cells through the immunophenotyping of reticulocytes
    • JM Navenot JY Muller D Blanchard 1998 Investigation of the survival of paroxysmal nocturnal hemoglobinuria red cells through the immunophenotyping of reticulocytes Transfusion 38 4 337 342 9595015 10.1046/j.1537-2995.1998. 38498257371.x 1:STN:280:DyaK1c3lsleksw%3D%3D (Pubitemid 28213588)
    • (1998) Transfusion , vol.38 , Issue.4 , pp. 337-342
    • Navenot, J.M.1    Muller, J.Y.2    Blanchard, D.3
  • 26
    • 0030906149 scopus 로고    scopus 로고
    • Antibody selection against CD52 produces a paroxysmal nocturnal haemoglobinuria phenotype in human lymphocytes by a novel mechanism
    • VC Taylor M Sims S Brett MC Field 1997 Antibody selection against CD52 produces a paroxysmal nocturnal haemoglobinuria phenotype in lymphocytes by a novel mechanism Biochem J 322 919 925 9148769 1:CAS:528:DyaK2sXit1Ort7w%3D (Pubitemid 27135644)
    • (1997) Biochemical Journal , vol.322 , Issue.3 , pp. 919-925
    • Taylor, V.C.1    Sims, M.2    Brett, S.3    Field, M.C.4
  • 27
    • 0026596863 scopus 로고
    • The problem of clonality in aplastic anemia: Dr Dameshek's riddle, restated
    • 1547338 1:STN:280:DyaK387ptVCksw%3D%3D
    • NS Young 1992 The problem of clonality in aplastic anemia: Dr Dameshek's riddle, restated Blood 79 6 1385 1392 1547338 1:STN:280:DyaK387ptVCksw%3D%3D
    • (1992) Blood , vol.79 , Issue.6 , pp. 1385-1392
    • Young, N.S.1
  • 28
    • 0028299834 scopus 로고
    • Somatic mutations and cellular selection in paroxysmal nocturnal haemoglobinuria
    • DOI 10.1016/S0140-6736(94)90068-X
    • M Bessler P Mason P Hillmen L Luzzatto 1994 Somatic mutations and cellular selection in paroxysmal nocturnal haemoglobinuria Lancet 343 8903 951 953 7909012 10.1016/S0140-6736(94)90068-X 1:STN:280:DyaK2c3htV2ksw%3D%3D (Pubitemid 24117232)
    • (1994) Lancet , vol.343 , Issue.8903 , pp. 951-953
    • Bessler, M.1    Mason, P.2    Hillmen, P.3    Luzzatto, L.4
  • 29
    • 62349130455 scopus 로고    scopus 로고
    • Development and evaluation of a stabilized whole-blood preparation as a process control material for screening of paroxysmal nocturnal hemoglobinuria by flow cytometry
    • 10.1002/cyto.b.20438
    • SJ Richards L Whitby MJ Cullen D Barnett, et al. 2009 Development and evaluation of a stabilized whole-blood preparation as a process control material for screening of paroxysmal nocturnal hemoglobinuria by flow cytometry Cytom B Clin Cytom 76 B 47 55 10.1002/cyto.b.20438
    • (2009) Cytom B Clin Cytom , vol.76 , pp. 47-55
    • Richards, S.J.1    Whitby, L.2    Cullen, M.J.3    Barnett, D.4
  • 30
    • 58149235125 scopus 로고    scopus 로고
    • Detection of paroxysmal nocturnal hemoglobinuria clones in patients with myelodysplastic syndromes and related bone marrow diseases, with emphasis on diagnostic pitfalls and caveats
    • 19001281 10.3324/haematol.13601
    • SA Wang O Pozdnyakova JL Jorgensen J Medelros D Stachurski M Anderson A Raza BA Woda 2009 Detection of paroxysmal nocturnal hemoglobinuria clones in patients with myelodysplastic syndromes and related bone marrow diseases, with emphasis on diagnostic pitfalls and caveats Haematologica 94 1 29 37 19001281 10.3324/haematol.13601
    • (2009) Haematologica , vol.94 , Issue.1 , pp. 29-37
    • Wang, S.A.1    Pozdnyakova, O.2    Jorgensen, J.L.3    Medelros, J.4    Stachurski, D.5    Anderson, M.6    Raza, A.7    Woda, B.A.8
  • 31
    • 77950643154 scopus 로고    scopus 로고
    • Evaluation of hemostasis and endothelial function in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab
    • French Society of Hematology. 20081060 10.3324/haematol.2009.016121 1:CAS:528:DC%2BC3cXhtlWjs7fE
    • D Helley RP de Latour R Porcher CA Rodrigues I Galy-Fauroux J Matheron A Duval JF Schved AM Fischer G Socié French Society of Hematology 2010 Evaluation of hemostasis and endothelial function in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab Haematologica 95 4 574 581 20081060 10.3324/haematol.2009.016121 1:CAS:528:DC%2BC3cXhtlWjs7fE
    • (2010) Haematologica , vol.95 , Issue.4 , pp. 574-581
    • Helley, D.1    De Latour, R.P.2    Porcher, R.3    Rodrigues, C.A.4    Galy-Fauroux, I.5    Matheron, J.6    Duval, A.7    Schved, J.F.8    Fischer, A.M.9    Socié, G.10
  • 32
    • 77950822742 scopus 로고    scopus 로고
    • Effect of eculizumab on haemolysis-associated nitric oxide depletion, dyspnoea, and measures of pulmonary hypertension in patients with paroxysmal nocturnal haemoglobinuria
    • 20230403 10.1111/j.1365-2141.2010.08096.x 1:CAS:528:DC%2BC3cXms1yjs7g%3D
    • A Hill RP Rother X Wang SM Morris Jr K Quinn-Senger R Kelly SJ Richards M Bessler L Bell P Hillmen MT Gladwin 2010 Effect of eculizumab on haemolysis-associated nitric oxide depletion, dyspnoea, and measures of pulmonary hypertension in patients with paroxysmal nocturnal haemoglobinuria Br J Haematol 149 3 414 425 20230403 10.1111/j.1365-2141.2010.08096.x 1:CAS:528:DC%2BC3cXms1yjs7g%3D
    • (2010) Br J Haematol , vol.149 , Issue.3 , pp. 414-425
    • Hill, A.1    Rother, R.P.2    Wang, X.3    Morris Jr., S.M.4    Quinn-Senger, K.5    Kelly, R.6    Richards, S.J.7    Bessler, M.8    Bell, L.9    Hillmen, P.10    Gladwin, M.T.11


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