Bile acid malabsorption: An under-investigated differential diagnosis in patients presenting with diarrhea predominant irritable bowel syndrome type symptoms

Scandinavian Journal of Gastroenterology

Volumn 46, Issue 7-8, 2011, Pages 818-822

  Kurien, Matthew ^a   Evans, Kate E ^a   Leeds, John S ^a   Hopper, Andy D ^a   Harris, Andrew ^a   Sanders, David S ^a  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

Bile acid malabsorption; Chronic diarrhea; Functional diarrhea; Irritable bowel syndrome; SeHCAT

Indexed keywords

BILE ACID; HOMOCHOLIC ACID; SELENIUM 75; TAURINE; UNCLASSIFIED DRUG;

75 SELENIUM HOMOCHOLIC ACID TAURINE TEST; ADULT; ARTICLE; BILE ACID MALABSORPTION; CHOLECYSTECTOMY; CLINICAL FEATURE; COHORT ANALYSIS; CROHN DISEASE; DIARRHEA; DIFFERENTIAL DIAGNOSIS; FEMALE; HUMAN; IRRITABLE COLON; LABORATORY TEST; MAJOR CLINICAL STUDY; MALABSORPTION; MALE; MEDICAL RECORD; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BILE ACIDS AND SALTS; CHI-SQUARE DISTRIBUTION; CHOLECYSTECTOMY; CHRONIC DISEASE; CROHN DISEASE; DIAGNOSIS, DIFFERENTIAL; DIARRHEA; FEMALE; HUMANS; ILEAL DISEASES; IRRITABLE BOWEL SYNDROME; LOGISTIC MODELS; MALABSORPTION SYNDROMES; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; SELENIUM RADIOISOTOPES; TAUROCHOLIC ACID; YOUNG ADULT;

EID: 79960253793     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2011.574728     Document Type: Article

References (21)

1. Fernandez-Banares F, Esteve M, Salas A, Alsina M, Farre C, Gonzalez C, et al. Systematic evaluation of the causes of chronic watery diarrhea with functional characteristics. Am J Gastroenterol 2007;102(11):2520-8. (Pubitemid 47631771)
2. Fan X, Sellin JH. Review article: small intestinal bacterial overgrowth, bile acid malabsorption and gluten intolerance as possible causes of chronic watery diarrhoea. Aliment Pharmacol Ther 2009;29(10):1069-77.
3. Wedlake L, A'Hern R, Russell D, Thomas K, Walters JR, Andreyev HJ. Systematic review: the prevalence of idiopathic bile acid malabsorption as diagnosed by SeHCAT scanning in patients with diarrhoea-predominant irritable bowel syndrome. Aliment Pharmacol Ther 2009;30(7):707-17.
4. Pattni S, Walters JR. Recent advances in the understanding of bile acid malabsorption. Br Med Bull 2009;92:79-93.
5. Nyhlin H, Merrick MV, Eastwood MA, Brydon WG. Evaluation of ileal function using 23-selena-25-homotaurocholate, a-gamma-labeled conjugated bile acid. Initial clinical assessment. Gastroenterology 1983;84(1):63-8. (Pubitemid 13198290)
6. Wildt S, Norby Rasmussen S, Lysgard Madsen J, Rumessen JJ. Bile acid malabsorption in patients with chronic diarrhoea: clinical value of SeHCAT test. Scand J Gastroenterol 2003;38(8):826-30. (Pubitemid 37011574)
7. Hofmann AF, Bolder U. Detection of bile acid malabsorption by the SeHCAT test. Gastroenterol Clin Biol 1994; 18(10):847-51.
8. Sinha L, Liston R, Testa HJ, Moriarty KJ. Idiopathic bile acid malabsorption: qualitative and quantitative clinical features and response to cholestyramine. Aliment Pharmacol Ther 1998;12(9):839-44. (Pubitemid 28428947)
9. Khalid U, Lalji A, Stafferton R, Andreyev J. Bile acid malabsoption: a forgotten diagnosis? Clin Med 2010;10(2): 124-6.
10. Sanders DS, Carter MJ, Hurlstone DP, Pearce A, Ward AM, McAlindon ME, et al. Association of adult coeliac disease with irritable bowel syndrome: a case-control study in patients fulfilling ROME II criteria referred to secondary care. Lancet 2001;358(9292):1504-8. (Pubitemid 33055702)
11. GE Healthcare (2009) SeHCAT Prescribing Information. Amersham, UK: GE Healthcare, (Ref Type: Pamphlet).
12. Merrick MV, Eastwood MA, Ford MJ. Is bile acid malabsorption underdiagnosed? An evaluation of accuracy of diagnosis by measurement of SeHCAT retention. Br Med J (Clin Res Ed) 1985;290(6469):665-8. (Pubitemid 15103859)
13. Ung KA, Olofsson G, Fae A, Kilander A, Ohlsson C, Jonsson O. In vitro determination of active bile acid absorption in small biopsy specimens obtained endoscopically or surgically from the human intestine. Eur J Clin Invest 2002; 32(2):115-21. (Pubitemid 36232732)
14. Smith MJ, Cherian P, Raju GS, Dawson BF, Mahon S, Bardhan KD. Bile acid malabsorption in persistent diarrhoea. J R Coll Physicians Lond 2000;34(5):448-51.
15. Ford GA, Preece JD, Davies IH, Wilkinson SP. Use of the SeHCAT test in the investigation of diarrhoea. Postgrad Med J 1992;68(798):272-6.
16. Al-Hadrani A, Lavelle-Jones M, Kennedy N, Neill G, Sutton D, Cuschieri A. Bile acid malabsorption in patients with post-vagotomy diarrhoea. Ann Chir Gynaecol 1992; 81(4):351-3. (Pubitemid 23049004)
17. Ung KA, Kilander AF, Lindgren A, Abrahamsson H. Impact of bile acid malabsorption on steatorrhoea and symptoms in patients with chronic diarrhoea. Eur J Gastroenterol Hepatol 2000;12(5):541-7. (Pubitemid 30326621)
18. Scarpello JH, Hodgson E, Howlett HC. Effect of metformin on bile salt circulation and intestinal motility in type 2 diabetes mellitus. Diabet Med 1998;15(8):651-6. (Pubitemid 28355848)
19. Nakamura T, Kikuchi H, Takebe K, Ishii M, Imamura K, Yamada N, et al. Correlation between bile acid malabsorption and pancreatic exocrine dysfunction in patients with chronic pancreatitis. Pancreas 1994;9(5):580-4. (Pubitemid 24276948)
20. Sciarretta G, Vicini G, Fagioli G, Verri A, Ginevra A, Malaguti P. Use of 23-selena-25-homocholyltaurine to detect bile acid malabsorption in patients with illeal dysfunction or diarrhea. Gastroenterology 1986;91(1):1-9. (Pubitemid 16086647)
21. Thomas PD, Forbes A, Green J, Howdle P, Long R, Playford R, et al. Guidelines for the investigation of chronic diarrhoea, 2nd ed. Gut 2003;52(Suppl 5):v1-15.