Iron Storage Disease in Red Deer (Cervus elaphus elaphus) is not associated with Mutations in the HFE Gene

Journal of Comparative Pathology

Volumn 145, Issue 2-3, 2011, Pages 207-213

  Olias, P ^a   Weiss, A Th A ^a   Gruber, A D ^a   Klopfleisch, R ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Haemochromatosis; HFE gene; Liver; Red deer

Indexed keywords

DRINKING WATER; HFE PROTEIN; IRON;

AMINO ACID SUBSTITUTION; ANIMAL DISEASE; ARTICLE; BLOOD ANALYSIS; CACHEXIA; GENE MUTATION; GENETIC POLYMORPHISM; HAIR LOSS; HEART MUSCLE CELL; HEMOCHROMATOSIS; HEMOSIDEROSIS; HUMAN; IRON METABOLISM; KIDNEY TUBULE CELL; KUPFFER CELL; LIVER CELL; LIVER FIBROSIS; LIVER NECROSIS; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RED DEER; SEQUENCE ANALYSIS; WEIGHT REDUCTION;

AMINO ACID SEQUENCE; ANIMALS; DEER; HEMOCHROMATOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; IRON; LIVER; MALE; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION;

ANIMALIA; CERVIDAE; CERVUS ELAPHUS; CERVUS ELAPHUS ELAPHUS;

EID: 79960247004     PISSN: 00219975     EISSN: 15323129     Source Type: Journal    
DOI: 10.1016/j.jcpa.2010.12.012     Document Type: Article

References (28)

1. Allen K.J., Gurrin L.C., Constantine C.C., Osborne N.J., Delatycki M.B., et al. Iron-overload-related disease in HFE hereditary hemochromatosis. New England Journal of Medicine 2008, 358:221-230.
2. Ayonrinde O.T., Milward E.A., Chua A.C., Trinder D., Olynyk J.K. Clinical perspectives on hereditary hemochromatosis. Critical Reviews in Clinical Laboratory Sciences 2008, 45:451-484.
3. Beutler E., West C., Speir J.A., Wilson I.A., Worley M. The hHFE gene of browsing and grazing rhinoceroses: a possible site of adaptation to a low-iron diet. Blood Cells and Molecular Disease 2001, 27:342-350.
4. Borch-Iohnsen B., Thorstensen K. Iron distribution in the liver and duodenum during seasonal iron overload in Svalbard reindeer. Journal of Comparative Pathology 2009, 141:27-40.
5. Brayton C. Amyloidosis, hemochromatosis, and atherosclerosis in a roseate flamingo (Phoenicopterus ruber). Annals of the New York Academy of Sciences 1992, 653:184-190.
6. Brunt E.M., Olynyk J.K., Britton R.S., Janney C.G., Di Bisceglie A.M., et al. Histological evaluation of iron in liver biopsies: relationship to HFE mutations. American Journal of Gastroenterology 2000, 95:1788-1793.
7. Camaschella C., De Gobbi M., Roetto A. Hereditary hemochromatosis: progress and perspectives. Reviews in Clinical and Experimental Hematology 2000, 4:302-321.
8. Cornelissen H., Ducatelle R., Roels S. Successful treatment of a channel-billed toucan (Ramphastos vitellinus) with iron storage disease. Journal of Avian Medicine and Surgery 1995, 9:131-137.
9. Dooley J.S., Walker A.P., Macfarlane B., Worwood M. Genetic haemochromatosis. Report of a meeting of physicians and scientists at the Royal Free Hospital School of Medicine. Lancet 1997, 349:1688-1693.
10. Feder J.N., Gnirke A., Thomas W., Tsuchihashi Z., Ruddy D.A., et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nature Genetics 1996, 13:399-408.
11. Fleming R.E., Bacon B.R. Orchestration of iron homeostasis. New England Journal of Medicine 2005, 352:1741-1744.
12. Franchini M. Hereditary iron overload: update on pathophysiology, diagnosis, and treatment. American Journal of Hematology 2006, 81:202-209.
13. Franchini M., Veneri D. Recent advances in hereditary hemochromatosis. Annals of Hematology 2005, 84:347-352.
14. Giegerich R., Meyer F., Schleiermacher C. GeneFisher - software support for the detection of postulated genes. Proceedings of the International Conference on Intelligent Systems for Molecular Biology 1996, 4:68-77.
15. Gosselin S.J., Kramer L.W. Pathophysiology of excessive iron storage in mynah birds. Journal of the American Veterinary Medical Association 1983, 183:1238-1240.
16. Latunde-Dada G.O., McKie A.T., Simpson R.J. Animal models with enhanced erythropoiesis and iron absorption. Biochimica et Biophysica Acta 2006, 1762:414-423.
17. Lavoie J.P., Teuscher E. Massive iron overload and liver fibrosis resembling haemochromatosis in a racing pony. Equine Veterinary Journal 1993, 25:552-554.
18. Mendes A.I., Ferro A., Martins R., Picanco I., Gomes S., et al. Non-classical hereditary hemochromatosis in Portugal: novel mutations identified in iron metabolism-related genes. Annals of Hematology 2009, 88:229-234.
19. Mete A., Jalving R., van Oost B.A., van Dijk J.E., Marx J.J. Intestinal over-expression of iron transporters induces iron overload in birds in captivity. Blood Cells and Molecular Disease 2005, 34:151-156.
20. Nielsen M., Lundegaard C., Lund O., Petersen T.N. CPHmodels-3.0 - remote homology modeling using structure-guided sequence profiles. Nucleic Acids Research 2010, 38(Suppl.):W576-581.
21. O'Toole D., Kelly E.J., McAllister M.M., Layton A.W., Norrdin R.W., et al. Hepatic failure and hemochromatosis of Salers and Salers-cross cattle. Veterinary Pathology 2001, 38:372-389.
22. Pietrangelo A. Haemochromatosis. Gut 2003, 52(Suppl. 2):ii23-30.
23. Pietrangelo A. Non-HFE hemochromatosis. Seminars in Liver Disease 2005, 25:450-460.
24. Puls R. Mineral Levels in Animal Health: Diagnostic Data 1994, Sherpa International, Clearbrook, pp. 203-204. 2nd Edit.
25. Sanchez M., Queralt R., Bruguera M., Rodes J., Oliva R. Cloning, sequencing and characterization of the rat hereditary hemochromatosis promoter: comparison of the human, mouse and rat HFE promoter regions. Gene 1998, 225:77-87.
26. Waheed A., Parkkila S., Saarnio J., Fleming R.E., Zhou X.Y. Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum. Proceedings of the National Academy of Sciences USA 1999, 96:1579-1584.
27. WHO. http://www.who.int/water_sanitation_health/dwq/.../iron.pdf.
28. Worwood M. Inherited iron loading: genetic testing in diagnosis and management. Blood Reviews 2005, 19:69-88.