Orchestration of iron homeostasis

New England Journal of Medicine

Volumn 352, Issue 17, 2005, Pages 1741-1744

  Fleming, Robert E ^a   Bacon, Bruce R ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEPCIDIN; HFE PROTEIN; IRON; IRON REDUCTASE; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; OXIDOREDUCTASE; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ANEMIA; FEEDBACK SYSTEM; GENE TECHNOLOGY; HEMOCHROMATOSIS; HOMEOSTASIS AND REGULATION; IRON ABSORPTION; IRON KINETICS; IRON STORAGE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW;

ANTIMICROBIAL CATIONIC PEPTIDES; HEMOCHROMATOSIS; HEPATOCYTES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HOMEOSTASIS; HUMANS; INTESTINAL ABSORPTION; IRON; MEMBRANE PROTEINS; MUTATION;

EID: 17644363328     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMp048363     Document Type: Review

References (5)

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2. Pietrangelo A. Hereditary hemochromatosis - a new look at an old disease. N Engl J Med 2004;350:2383-97.
3. Hentze MW, Muckenthaler MU, Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell 2004;117:285-97.
4. Ganz T. Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood 2003;102:783-8.
5. Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 2004;306:2090-3.