Adiponectin resides in mouse skin and upregulates hyaluronan synthesis in dermal fibroblasts

Connective Tissue Research

Volumn 52, Issue 4, 2011, Pages 322-328

  Akazawa, Yumiko ^a   Sayo, Tetsuya ^a   Sugiyama, Yoshinori ^a   Sato, Takashi ^b   Akimoto, Noriko ^b   Ito, Akira ^b   Inoue, Shintaro ^a  

^a KANEBO LTD   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Adiponectin; Aging; Dermal fibroblast; Hyaluronan; Sebocyte

Indexed keywords

ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; HYALURONAN SYNTHASE 2; HYALURONIC ACID; MESSENGER RNA; SYNTHETASE; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXOCRINE CELL; FIBROBLAST CULTURE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLYCOSAMINOGLYCAN METABOLISM; HUMAN; HUMAN CELL; KERATINOCYTE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BLOOD LEVEL; PROTEIN CONTENT; PROTEIN LOCALIZATION; SEBACEOUS CELL; SKIN FIBROBLAST; UPREGULATION;

ADIPONECTIN; ANIMALS; CELLS, CULTURED; FIBROBLASTS; HUMANS; HYALURONIC ACID; KERATINOCYTES; MALE; MICE; RECEPTORS, ADIPONECTIN; SKIN;

EID: 79960242191     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.3109/03008207.2010.528566     Document Type: Article

References (42)

1. Spiegelman, B.M., and Flier, J.S. (1996). Adipogenesis and obesity: Rounding out the big picture. Cell 87:377-389. (Pubitemid 26374313)
2. Goodson, W.H. 3rd., and Hunt, T.K. (1986). Wound collagen accumulation in obese hyperglycemic mice. Diabetes 35:491-495. (Pubitemid 16078465)
3. Goren, I., Kampfer, H., Podda, M., Pfeilschifter, J., and Frank, S. (2003). Leptin and wound inflammation in diabetic ob/ob mice: Differential regulation of neutrophil and macrophage influx and a potential role for the scab as a sink for inflammatory cells and mediators. Diabetes 52:2821-2832. (Pubitemid 37339713)
4. Naldi, L., Chatenoud, L., Linder, D., Fortina, A.B., Peserico, A., Virgili, A.R., Bruni, P.L., Ingordo, V., Lo Scocco, G., Solaroli, C., Schena, D., Barba, A., Di Landro, A., Pezzarossa, E., Arcangeli, F., Gianni, C., Betti, R., Carli, P., Farris, A., Barabino, G.F., and La Vecchia, C. (2005). Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: Result from an Italian case-control study. J. Invest. Dermatol. 125:61-67. (Pubitemid 40981424)
5. Yosipovitch, G., DeVore, A., and Dawn, A. (2007). Obesity and the skin: Skin physiology and skin manifestations of obesity. J. Am. Acad. Dermatol. 56:901-916. (Pubitemid 46720212)
6. Johnston, A., Arnadottir, S., Gudjonsson, J.E., Aphale, A., Sigmarsdottir, A.A., Gunnarsson, S.I., Steinsson, J.T., Elder, J.T., and Valdimarsson, H. (2008). Obesity in psoriasis: Leptin and resistin as mediators of cutaneous inflammation. Br. J. Dermatol. 159:342-350. (Pubitemid 352009847)
7. Considine, R.V., Sinha, M.K., Heiman, M.L., Kriauciunas, A., Stephens, T.W., Nyce, M.R., Ohannesian, J.P., Marco, C.C., McKee, L.J., Bauer, T.L., and Caro, J.F. (1996). Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N. Engl. J. Med. 334:292-295. (Pubitemid 26033933)
8. Ryan, A.S., Berman, D.M., Nicklas, B.J., Sinha, M., Gingerich, R.L., Meneilly, G.S., Egan, J.M., and Elahi, D. (2003). Plasma adiponectin and leptin levels, body composition, and glucose utilization in adult women with wide ranges of age and obesity. Diabetes Care 26:2383-2388. (Pubitemid 36993330)
9. Berg, A.H., Combs, T.P., Du, X., Brownless, M., and Scherer, P.E. (2001). The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat. Med. 7:947-953. (Pubitemid 32756433)
10. Fruebis, J., Tsao, T.S., Javorschi, S., Ebbets-Reed, D., Erickson, M.R.S., Yen, F.T., Bihain, B.E., and Lodish, H.F. (2001). Proteolytic cleavage product of 30-kDa adipocyte complementrelated protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc. Natl. Acad. Sci. USA 98:2005-2010. (Pubitemid 32165613)
11. Yamauchi, T., Kamon, J., Waki, H., Terauchi, Y., Kubota, N., Hara, K., Mori, Y., Ide, T., Murakami, K., Tsuboyama- Kasaoka, N., Ezaki, O., Akanuma, Y., Gavrilova, O., Vinson, C., Reitman, M.L., Kagechika, H., Shudo, K., Yoda, M., Nakano, Y., Tobe, K., Nagai, R., Kimura, S., Tomita, M., Froguel, P., and Kadowaki, T. (2001). The fat-derived hor- mone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 7:941-946. (Pubitemid 32756432)
12. Ouchi, N., Kihara, S., Arita, Y., Nishida, M., Matsuyama, A., Okamoto, Y., Ishigami, M., Kuriyama, H., Kishida, K., Nishizawa, H., Hotta, K., Muraguchi, M., Ohmoto, Y., Yamashita, S., Funahashi, T., and Matsuzawa, Y. (2001). Adipocytederived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation 103:1057-1063. (Pubitemid 32200177)
13. Hu, E., Liang, P., and Spiegelman, B.M. (1996). AdipoQ is a novel adipose-specific gene dysregulated in obesity. J. Biol. Chem. 271:10697-10703. (Pubitemid 26145805)
14. Arita, Y., Kihara, S., Ouchi, N., Takahashi, M., Maeda, K., Miyagawa, J., Hotta, K., Shimomura, I., Nakamura, T., Miyaoka, K., Kuriyama, H., Nishida, M., Yamashita, S., Okubo, K., Matsubara, K., Muraguchi, M., Ohmoto, Y., Funahashi, T., and Matsuzawa, Y. (1999). Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem. Biophys. Res. Commun. 257:79-83. (Pubitemid 29299050)
15. Frank, S., Stallmeyer, B., Kampfer, H., Kolb, N., and Pfeilschifter, J. (2000). Leptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair. J. Clin. Invest. 106:501-509. (Pubitemid 30666383)
16. Cerman, A.A., Bozkurt, S., Sav, A., Tulunay, A., Elbasi, M.O., and Ergun, T. (2008). Serum leptin levels, skin leptin and leptin receptor expression in psoriasis. Br. J. Dermatol. 159:820-826.
17. Meyer, L.J.M., and Stern, R. (1994). Age-dependent changes of hyaluronan in human skin. J. Invest. Dermatol. 102:385-389. (Pubitemid 24095508)
18. Manuskiatti, W., and Maibach, H.I. (1996). Hyaluronic acid and skin: Wound healing and aging. Int. J. Dermatol. 35:539-544. (Pubitemid 26261919)
19. Sugiyama, Y., Shimada, A., Sayo, T., Sakai, S., and Inoue, S. (1998). Putative hyaluronan synthase mRNA are expressed in mouse skin and TGF-b upregulates their expression in cultured human skin cells. J. Invest. Dermatol. 110:116-121. (Pubitemid 28105843)
20. Zhang, W., Watson, C.E., Liu, C., Williams, K.J., and Werth, V.P. (2000). Glucocorticoids induce a near-total suppression of hyaluronan synthase mRNA in dermal fibroblasts and in osteoblasts: A molecular mechanism contributing to organ atrophy. Biochem. J. 349:91-97. (Pubitemid 30440169)
21. Yamada, Y., Itano, N., Hata, K., Ueda, M., and Kimata, K. (2004). Differential regulation by IL-1b and EGF of expression of three different hyaluronan synthases in oral mucosal epithelial cells and fibroblasts and dermal fibroblasts: Quantitative analysis using real-time RT-PCR. J. Invest. Dermatol. 122:631-639. (Pubitemid 38471328)
22. Sayo, T., Sugiyama, Y., Takahashi, Y., Ozawa, N., Sakai, S., Ishikawa, O., Tamura, M., and Inoue, S. (2002). Hyaluronan synthase 3 regulates hyaluronan synthesis in cultured human keratinocytes. J. Invest. Dermatol. 118:43-48. (Pubitemid 34107422)
23. Kakizaki, I., Itano, N., Kimata, K., Hanada, K., Kon, A., Yamaguchi, M., Takahashi, T., and Takagaki, K. (2008). Upregulation of hyaluronan synthase genes in cultured human epidermal keratinocytes by UVB irradiation. Arch. Biochem. Biophys. 471:85-93.
24. Ohtani, T., Memezawa, A., Okuyama, R., Sayo, T., Sugiyama, Y., Inoue, S., and Aiba, S. (2009). Increased hyaluronan production and decreased E-cadherin expression by cytokine-stimulated keratinocytes lead to spongiosis formation. J. Invest. Dermatol. 129:1412-1420.
25. Ghersetich, I., Lotti, T., Campanile, G., Grappone, C., and Dini, G. (1994). Hyaluronan acid in cutaneous intrinsic aging. Int. J. Dermatol. 33:119-122. (Pubitemid 24141902)
26. Berenson, G.S., Radhakrishnamurthy, B., Dalferes, E.R. Jr., Ruiz, H., Srinivasan, S.R., Plavidal, F., and Brickman, F. (1972). Connective tissue macromolecular changes in rats with experimentally induced diabetes and hyperinsulinism. Diabetes 21:733-743.
27. Dalferes, E.R. Jr., Radhakrishnamurthy, B., Crouch, M.S., and Berenson, G.S. (1975). A study of connective tissue macromolecules in skin of mice with goldthioglucose-induced obesity. Proc. Soc. Exp. Biol. Med. 148:918-924.
28. Cechowska-Pasko, M., Palka, J., and Bankowski, E. (1999). Decreased biosynthesis of glycosaminoglycans in the skin of rats with chronic diabetes mellitus. Exp. Toxic. Pathol. 51: 239-243. (Pubitemid 29204895)
29. Sato, T., Imai, N., Akimoto, N., Saiguchi, T., Kitamura, K., and Ito, A. (2001). Epidermal growth factor and 1a, 25-dihydroxyvitamine D3 suppress lipogenesis in hamster sebaceous gland cells in vitro. J. Invest. Dermatol. 117:965-970. (Pubitemid 33001218)
30. Iwata, C., Akimoto, N., Sato, T., Morokuma, Y., and Ito, A. (2005). Augmentation of lipogenesis by 15-deoxy-Ä12,14-prostaglandin J2 in hamster sebaceous glands: Identification of cytochrome P-450-mediated 15-deoxy-Ä12,14-prostaglandin J2 production. J. Invest. Dermatol. 125:865-872.
31. Trivedi, N.R., Cong, Z., Nelson, A.M., Albert, A.J., Rosamilia, L.L., Sivarajah, S., Gilliland, K.L., Liu, W., Mauger, D.T., Gabbay, R.A., and Thiboutot, D.M. (2006). Peroxisome proliferator-activated receptors increase human sebum production. J. Invest. Dermatol. 126:2002-2009.
32. Akimoto, N., Sato, T., Iwata, C., Koshizuka, M., Shibata, F., Nagai, A., Sumida, M., and Ito, A. (2005). Expression of perilipin A on the surface of lipid droplets increases along with the differentiation of hamster sebocytes in vivo and in vitro. J. Invest. Dermatol. 124:1127-1133. (Pubitemid 40847398)
33. Zhang, L., Li, W.H., Anthonavage, M., and Eisinger, M. (2006). Melanocortin-5 receptor: A marker of human sebocyte differentiation. Peptides 27:413-420. (Pubitemid 43162913)
34. Lo Celso, C., Berta, M.A., Braun, K.M., Frye, M., Lyle, S., Zouboulis, C.C., and Watt, F.M. (2008). Characterization of bipotential epidermal progenitors derived from human sebaceous gland: Contrasting roles of c-Myc and beta-catenin. Stem Cells 26: 1241-1252.
35. Rilla, K., Pasonen-Seppanen, S., Rieppo, J., Tammi, M., and Tammi, R. (2004). The hyaluronan synthesis inhibitor 4-methylumbelliferone prevents keratinocyte activation and epidermal hyperproliferation induced by epidermal growth factor. J. Invest. Dermatol. 123:708-714. (Pubitemid 39281612)
36. Longas, M.O., Russell, C.S., and He, X.Y. (1987). Evidence for structural changes in dermatan sulfate and hyaluronic acid with aging. Carbohydr. Res. 159:127-136.
37. Maeda, N., Takahashi, M., Funahashi, T., Kihara, S., Nishizawaj H., Kishida, K., Nagaretani, H., Matsuda, M., Komuro, R., Ouchi, N., Kuriyama, H., Hotta, K., Nakamura, T., Shimomura, I., and Matsuzawa, Y. (2001). PPARg ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 50:2094-2099. (Pubitemid 33643677)
38. Bertheim, U., Engstrom-Laurent, A., Hofer, P.A., Hallgren, P., Asplund, J., and Hellstrom, S. (2002). Loss of hyaluronan in the basement membrane zone of the skin correlates to the degree of stiff hands in diabetes patients. Acta Dermatol. Venereol. 82:329-334. (Pubitemid 35221783)
39. Rosenbloom, A.L., Sliverstein, J.H., Lezotte, D.C., Richardson, K., and McCallum, M. (1981). Limited joint mobility in childhood diabetes mellitus indicates increased risk for microvascular disease. N. Engl. J. Med. 305:191-194. (Pubitemid 11040737)
40. Ezure, T., and Amano, S. (2007). Adiponectin and leptin upregulate extracellular matrix production by dermal fibroblasts. BioFactors 31:229-236. (Pubitemid 352789891)
41. Kawai, K., Kageyama, A., Tsumano, T., Nishimoto, S., Fukuda, K., Yokoyama, S., Oguma, T., Fujita, K., Yoshimoto, S., Yanai, A., and Kakibuchi, M. (2008). Effects of adiponectin on growth and differentiation of human keratinocytes - Implication of impaired wound healing in diabetes. Biochem. Biophys. Res. Commun. 374:269-273.
42. Hug, C., Wang, J., Ahmad, N.S., Bogan, J.S., Tsao, T.S., and Lodish, H.F. (2004). T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proc. Natl. Acad. Sci. USA 101:10308-10313. (Pubitemid 38924921)