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Volumn 217, Issue 1, 2011, Pages 263-267

Plasma proprotein convertase subtilisin kexin type 9 is not altered in subjects with impaired glucose metabolism and type 2 diabetes mellitus, but its relationship with non-HDL cholesterol and apolipoprotein B may be modified by type 2 diabetes mellitus: The CODAM study

Author keywords

Diabetes mellitus; Dyslipidemia; Insulin resistance; PCSK9

Indexed keywords

ANTIHYPERTENSIVE AGENT; APOLIPOPROTEIN B; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9; SERINE PROTEINASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 79960238532     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2011.03.023     Document Type: Article
Times cited : (63)

References (27)
  • 1
    • 0141500237 scopus 로고    scopus 로고
    • Lipoprotein distribution in the metabolic syndrome, type 2 diabetes mellitus, and familial combined hyperlipidemia
    • Ayyobi A.F., Brunzell J.D. Lipoprotein distribution in the metabolic syndrome, type 2 diabetes mellitus, and familial combined hyperlipidemia. Am J Cardiol 2003, 92:27-33.
    • (2003) Am J Cardiol , vol.92 , pp. 27-33
    • Ayyobi, A.F.1    Brunzell, J.D.2
  • 2
    • 0030986959 scopus 로고    scopus 로고
    • Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM
    • Malmstrom R, Packard C.J., Caslake M., et al. Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM. Diabetologia 1997, 40:454-462.
    • (1997) Diabetologia , vol.40 , pp. 454-462
    • Malmstrom, R.1    Packard, C.J.2    Caslake, M.3
  • 3
    • 33644827082 scopus 로고    scopus 로고
    • Overproduction of large VLDL particles is driven by increased liver fat content in man
    • Adiels M., Taskinen M.R., Packard C., et al. Overproduction of large VLDL particles is driven by increased liver fat content in man. Diabetologia 2006, 1-11.
    • (2006) Diabetologia , pp. 1-11
    • Adiels, M.1    Taskinen, M.R.2    Packard, C.3
  • 4
    • 0023220351 scopus 로고
    • Integrated study of low density lipoprotein metabolism and very low density lipoprotein metabolism in non-insulin-dependent diabetes
    • Howard B.V., Abbott W.G., Beltz W.F., et al. Integrated study of low density lipoprotein metabolism and very low density lipoprotein metabolism in non-insulin-dependent diabetes. Metabolism 1987, 36:870-877.
    • (1987) Metabolism , vol.36 , pp. 870-877
    • Howard, B.V.1    Abbott, W.G.2    Beltz, W.F.3
  • 5
    • 0020672438 scopus 로고
    • Plasma low density lipoprotein transport kinetics in noninsulin-dependent diabetes mellitus
    • Kissebah A.H., Alfarsi S., Evans D.J., Adams P.W. Plasma low density lipoprotein transport kinetics in noninsulin-dependent diabetes mellitus. J Clin Invest 1983, 71:655-667.
    • (1983) J Clin Invest , vol.71 , pp. 655-667
    • Kissebah, A.H.1    Alfarsi, S.2    Evans, D.J.3    Adams, P.W.4
  • 6
    • 0041667865 scopus 로고    scopus 로고
    • Cell surface expression of LDL receptor is decreased in type 2 diabetic patients and is normalized by insulin therapy
    • Duvillard L., Florentin E., Lizard G., et al. Cell surface expression of LDL receptor is decreased in type 2 diabetic patients and is normalized by insulin therapy. Diabetes Care 2003, 26:1540-1544.
    • (2003) Diabetes Care , vol.26 , pp. 1540-1544
    • Duvillard, L.1    Florentin, E.2    Lizard, G.3
  • 7
    • 34248366942 scopus 로고    scopus 로고
    • Unravelling the functional significance of PCSK9
    • Lambert G. Unravelling the functional significance of PCSK9. Curr Opin Lipidol 2007, 18:304-309.
    • (2007) Curr Opin Lipidol , vol.18 , pp. 304-309
    • Lambert, G.1
  • 9
    • 69549138572 scopus 로고    scopus 로고
    • Plasma PCSK9 is associated with age, sex, and multiple metabolic markers in a population-based sample of children and adolescents
    • Baass A., Dubuc G., Tremblay M., et al. Plasma PCSK9 is associated with age, sex, and multiple metabolic markers in a population-based sample of children and adolescents. Clin Chem 2009, 55:1637-1645.
    • (2009) Clin Chem , vol.55 , pp. 1637-1645
    • Baass, A.1    Dubuc, G.2    Tremblay, M.3
  • 10
    • 65549153242 scopus 로고    scopus 로고
    • Low-grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study
    • Jacobs M., van Greevenbroek M.M., van der Kallen C.J., et al. Low-grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study. Eur J Clin Invest 2009, 39:437-444.
    • (2009) Eur J Clin Invest , vol.39 , pp. 437-444
    • Jacobs, M.1    van Greevenbroek, M.M.2    van der Kallen, C.J.3
  • 11
    • 77956797294 scopus 로고    scopus 로고
    • High-dose atorvastatin causes a rapid sustained increase in human serum PCSK9 and disrupts its correlation with LDL cholesterol
    • Welder G., Zineh I., Pacanowski M.A., Troutt J.S., Cao G., Konrad R.J. High-dose atorvastatin causes a rapid sustained increase in human serum PCSK9 and disrupts its correlation with LDL cholesterol. J Lipid Res 2010, 51:2714-2721.
    • (2010) J Lipid Res , vol.51 , pp. 2714-2721
    • Welder, G.1    Zineh, I.2    Pacanowski, M.A.3    Troutt, J.S.4    Cao, G.5    Konrad, R.J.6
  • 12
    • 79960251970 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Report of a WHO consultation. Part 1: diagnosis and classification of diabetes mellitus. Geneva.
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Report of a WHO consultation. Part 1: diagnosis and classification of diabetes mellitus. Geneva; 1999.
    • (1999)
  • 13
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18:499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 14
    • 0033574249 scopus 로고    scopus 로고
    • A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease study group
    • Levey A.S., Bosch J.P., Lewis J.B., Greene T., Rogers N., Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease study group. Ann Intern Med 1999, 130:461-470.
    • (1999) Ann Intern Med , vol.130 , pp. 461-470
    • Levey, A.S.1    Bosch, J.P.2    Lewis, J.B.3    Greene, T.4    Rogers, N.5    Roth, D.6
  • 15
    • 34848861377 scopus 로고    scopus 로고
    • Serum proprotein convertase subtilisin kexin type 9 is correlated directly with serum LDL cholesterol
    • Alborn W.E., Cao G., Careskey H.E., et al. Serum proprotein convertase subtilisin kexin type 9 is correlated directly with serum LDL cholesterol. Clin Chem 2007, 53:1814-1819.
    • (2007) Clin Chem , vol.53 , pp. 1814-1819
    • Alborn, W.E.1    Cao, G.2    Careskey, H.E.3
  • 17
    • 0034712706 scopus 로고    scopus 로고
    • Elevated HDL cholesterol is a risk factor for ischemic heart disease in white women when caused by a common mutation in the cholesteryl ester transfer protein gene
    • Agerholm-Larsen B., Nordestgaard B.G., Steffensen R., Jensen G., Tybjaerg-Hansen A. Elevated HDL cholesterol is a risk factor for ischemic heart disease in white women when caused by a common mutation in the cholesteryl ester transfer protein gene. Circulation 2000, 101:1907-1912.
    • (2000) Circulation , vol.101 , pp. 1907-1912
    • Agerholm-Larsen, B.1    Nordestgaard, B.G.2    Steffensen, R.3    Jensen, G.4    Tybjaerg-Hansen, A.5
  • 18
    • 33847653409 scopus 로고    scopus 로고
    • Impact of disease characteristics on the efficacy of duloxetine in diabetic peripheral neuropathic pain
    • Ziegler D., Pritchett Y.L., Wang F., et al. Impact of disease characteristics on the efficacy of duloxetine in diabetic peripheral neuropathic pain. Diabetes Care 2007, 30:664-669.
    • (2007) Diabetes Care , vol.30 , pp. 664-669
    • Ziegler, D.1    Pritchett, Y.L.2    Wang, F.3
  • 19
    • 44849086762 scopus 로고    scopus 로고
    • Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment
    • Lambert G., Ancellin N., Charlton F., et al. Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment. Clin Chem 2008, 54:1038-1045.
    • (2008) Clin Chem , vol.54 , pp. 1038-1045
    • Lambert, G.1    Ancellin, N.2    Charlton, F.3
  • 20
    • 0141706620 scopus 로고    scopus 로고
    • Thyroid hormone regulation and cholesterol metabolism are connected through Sterol Regulatory Element-Binding Protein-2 (SREBP-2)
    • Shin D.J., Osborne T.F. Thyroid hormone regulation and cholesterol metabolism are connected through Sterol Regulatory Element-Binding Protein-2 (SREBP-2). J Biol Chem 2003, 278:34114-34118.
    • (2003) J Biol Chem , vol.278 , pp. 34114-34118
    • Shin, D.J.1    Osborne, T.F.2
  • 21
    • 0035044676 scopus 로고    scopus 로고
    • The relationship between thyrotropin and low density lipoprotein cholesterol is modified by insulin sensitivity in healthy euthyroid subjects
    • Bakker S.J., ter Maaten J.C., Popp-Snijders C., Slaets J.P., Heine R.J., Gans R.O. The relationship between thyrotropin and low density lipoprotein cholesterol is modified by insulin sensitivity in healthy euthyroid subjects. J Clin Endocrinol Metab 2001, 86:1206-1211.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1206-1211
    • Bakker, S.J.1    ter Maaten, J.C.2    Popp-Snijders, C.3    Slaets, J.P.4    Heine, R.J.5    Gans, R.O.6
  • 22
    • 77956699129 scopus 로고    scopus 로고
    • Why is non-high-density lipoprotein cholesterol a better marker of the risk of vascular disease than low-density lipoprotein cholesterol?
    • Sniderman A., McQueen M., Contois J., Williams K., Furberg C.D. Why is non-high-density lipoprotein cholesterol a better marker of the risk of vascular disease than low-density lipoprotein cholesterol?. J Clin Lipidol 2010, 4:152-155.
    • (2010) J Clin Lipidol , vol.4 , pp. 152-155
    • Sniderman, A.1    McQueen, M.2    Contois, J.3    Williams, K.4    Furberg, C.D.5
  • 23
    • 0037126526 scopus 로고    scopus 로고
    • Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report
    • Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report. Circulation 2002, 106:3143-3421.
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 24
    • 38949109659 scopus 로고    scopus 로고
    • Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9
    • Careskey H.E., Davis R.A., Alborn W.E., Troutt J.S., Cao G., Konrad R.J. Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9. J Lipid Res 2008, 49:394-398.
    • (2008) J Lipid Res , vol.49 , pp. 394-398
    • Careskey, H.E.1    Davis, R.A.2    Alborn, W.E.3    Troutt, J.S.4    Cao, G.5    Konrad, R.J.6
  • 25
    • 77956230636 scopus 로고    scopus 로고
    • Plasma PCSK9 is increased by fenofibrate and atorvastatin in a non-additive fashion in diabetic patients
    • Costet P., Hoffmann M.M., Cariou B., Guyomarc'h Delasalle B., Konrad T., Winkler K. Plasma PCSK9 is increased by fenofibrate and atorvastatin in a non-additive fashion in diabetic patients. Atherosclerosis 2010, 212:246-251.
    • (2010) Atherosclerosis , vol.212 , pp. 246-251
    • Costet, P.1    Hoffmann, M.M.2    Cariou, B.3    Guyomarc'h Delasalle, B.4    Konrad, T.5    Winkler, K.6
  • 26
    • 77955046691 scopus 로고    scopus 로고
    • Fenofibrate concomitantly decreases serum proprotein convertase subtilisin/kexin type 9 and very-low-density lipoprotein particle concentrations in statin-treated type 2 diabetic patients
    • Chan D.C., Hamilton S.J., Rye K.A., et al. Fenofibrate concomitantly decreases serum proprotein convertase subtilisin/kexin type 9 and very-low-density lipoprotein particle concentrations in statin-treated type 2 diabetic patients. Diabetes Obes Metab 2010, 12:752-756.
    • (2010) Diabetes Obes Metab , vol.12 , pp. 752-756
    • Chan, D.C.1    Hamilton, S.J.2    Rye, K.A.3
  • 27
    • 67649834056 scopus 로고    scopus 로고
    • A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates
    • Chan J.C., Piper D.E., Cao Q., et al. A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc Natl Acad Sci USA 2009, 106:9820-9825.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9820-9825
    • Chan, J.C.1    Piper, D.E.2    Cao, Q.3


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