Secondary hyperparathyroidism and anemia. Effects of a calcimimetic on the control of anemia in chronic hemodialysed patients. Pilot Study;Hyperparathyroïdie secondaire et anémie. Effets d'un calcimimétique sur le contrôle de l'anémie des hémodialysés chroniques. Étude pilote

Nephrologie et Therapeutique

Volumn 7, Issue 4, 2011, Pages 229-236

  Mpio, Ignace ^a   Boumendjel, Nourredine ^a   Karaaslan, Husseyin ^a   Arkouche, Walid ^a   Lenz, Alexandra ^a   Cardozo, Carlos ^a   Cardozo, Jorge ^a   Pastural Thaunat, Myriam ^a   Fouque, Denis ^a   Silou, Jacques ^b   Attaf, David ^c   Laville, Maurice ^a  

^a AURAL Association pour l'Utilisation du Rein Artificiel à Lyon   (France)

^b CENTRE HOSPITALIER LYON SUD   (France)

^c Centre Hospitalier de Nevers   (France)

Author keywords

Anemia; Calcimimetic; cinacalcet; erythropoiesis stimulating agents; Erythropoietin resistance index; Secondary hyperparathyroidism

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; ANTIANEMIC AGENT; CALCIUM; CINACALCET; HEMOGLOBIN; PARATHYROID HORMONE; PHOSPHATE;

ADULT; ANEMIA; ARTICLE; BONE METABOLISM; CALCIUM BLOOD LEVEL; CLINICAL ARTICLE; DISEASE SEVERITY; DRUG RESPONSE; HEMODIALYSIS; HUMAN; IRON INTAKE; LONG TERM CARE; PARATHYROID HORMONE BLOOD LEVEL; PHOSPHATE BLOOD LEVEL; SECONDARY HYPERPARATHYROIDISM; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; ALKALINE PHOSPHATASE; ANEMIA, IRON-DEFICIENCY; BIOLOGICAL MARKERS; CALCIUM; CALCIUM PHOSPHATES; DRUG RESISTANCE; DRUG THERAPY, COMBINATION; FEMALE; HEMATINICS; HEMOGLOBINS; HUMANS; HYPERPARATHYROIDISM, SECONDARY; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; NAPHTHALENES; PHOSPHORUS; PILOT PROJECTS; PROSPECTIVE STUDIES; RENAL DIALYSIS; TREATMENT OUTCOME;

EID: 79960196051     PISSN: 17697255     EISSN: 18729177     Source Type: Journal    
DOI: 10.1016/j.nephro.2011.01.008     Document Type: Article

References (35)

1. K.U. Eckart Pathophysiology of renal anemia Clin Nephrol 53 2000 S2 S8
2. United States Renal Data System (USRDS) 2004. Annual Data Report. Am J Kidney Dis 2005; 45:8-280.
3. D.L. Mapes, A.A. Lopes, S. Satayathum, K.P. McCullough, D.A. Goodkin, and F. Locatelli Health related quality of life as a predictor of mortality and hospitalisation: the Dialysis Outcomes and Practice Patterns Study (DOPPS) Kidney Int 64 2003 339 349 (Pubitemid 36714189)
4. D.L. Regidor, J.D. Kopple, C.P. Kovesdy, R.D. Kilpatrick, C.J. McAllister, and J. Aronnovitz Associations between changes in hemoglobin and administered erythropoiesis-stimulating agent and survival in hemodialysis patients J Am Soc Nephrol 17 4 2006 1181 1191
5. P. Urena, K.U. Eckardt, E. sarfati, J. Zingraff, B. Zins, and J.B. Roullet Serum eryhtropoiesis in primary ans secondary hyperparathyroidism: effect of parathyroidectomy Nephron 59 1991 384 393
6. T.B. Drüeke, and K.U. Eckardt Role of secondary hyperparathyroidism in erythropoietin resistance of chronic renal failure patients Nephrol Dial Transplant 17 2002 28 31 (Pubitemid 34823069)
7. G. Sunder-Plasmann, and W.H. Horl Novel aspects of erythropoietin response in renal failure patients Nephrol Dial Transplant 16 S5 2001 40 44 (Pubitemid 32750428)
8. C.L. Lin, C.C. Hung, C.T. Yang, and C.C. Huang Improved anemia and reduced erythropoietin need by medical or surgical intervention of secundary hyperparathyroidism in hemodialysis patients Renal failure 26 3 2004 289 295
9. D. Brancaccio, M. Cozzolino, and M. Gallieni Hyperparathyroidism and anemia in uremic subjects: a combined therapeutic approach J Am Soc Nephrol 15 2004 S21 S24
10. S. Mandolfo, F. Malberti, M. Farina, G. Villa, R. Scanziani, and M. Surian Parathyroidectomy and respons to erythropoietin theray in anemic patients with chronic renal failure Nephrol Dial transplant 13 10 1998 2708 2709 (Pubitemid 28445910)
11. P. Urenas Clinical experience with cinacalcet HCL Nephrol Dial Transplant 19 S5 2004 V27 V33
12. S.M. Moe, G.M. Chertow, J.W. Cobrun, L.D. Quarles, W.G. Goodman, and G.A. Block Achieving NKF-K/DOQI bone metabolism and disease treatment goals with cinacalcet HCl Kidney Int 67 2005 760 771 (Pubitemid 40139871)
13. J.C. Souberbielle, A. Boutten, M.C. Carlier, D. Chevenne, G. Coumaros, and E. Lawson-Body Inter-method variability in PTH measurement: implication for the care of CKD patients Kidney Int 70 2006 354
14. J. Cunningham Achieving therapeutic targets in the treatment of secondary hyperparathyroidism Nephrol Dial Transplant 19 S5 2004 V9 V14
15. W.G. Goodmann Calcimimetic agents for the treatment of hyperparathyroidism Cur Opin Nephrol hypertens 10 2001 575 580
16. S. Nomura, Y. Ogawa, G. Osawa, M. Katagiri, T. Harada, and H. Nagahana Myelofibrosis secondary to renal osteodystrophy Nephron 72 4 1996 683 687 (Pubitemid 26098274)
17. G.A. Kayen, H.G. Muller, J. Ding, and G.M. Chertow Challenging the validity of the EPO index Am J Kidney Dis 47 1 2006 166
18. Martin KJ, Gonzalez EA, Slatopolsky EA. Renal osteodystrophy. In: Brenner BM, Rector FC, Editors. The Kidney, Philadelphia, 2004; 2256-96.
19. L.M. Calvi, G.B. Adams, K.W. Weibrecht, J.M. Weber, D.P. Olson, and M.C. Knight Osteoblastic cells regulate the haematopoietic stem-cell niche Nature 425 2003 841 846 (Pubitemid 37351468)
20. T.B. Drüeke Haematopoietic stem cells-role of calcium-sensing receptor in bone marrow homing Nephrol Dial Transplant 21 2006 2072 2074 (Pubitemid 44295030)
21. A. Felsenfeld, and J. Silver Pathophysiology and clinical manifestations of renal osteodystrophy K. Olgaard, Clinical guide to bone and mineral metabolism in CKD 2006 31 41
22. R.S. Taichman Blood and bone: two tissues whose fates are intertwined to create the hamatopoietic stem-cell niche Blood 105 2005 2631 2639 (Pubitemid 40446251)
23. A.J. Brown, C.S. Ritter, J.L. Finch, and E.A. Slatopolsky Decreased calcium-sensing receptor expression in hyperplastic parathyroid glands of uremic rats: role of dietary phosphate Kidney Int 55 1999 1284 1292 (Pubitemid 29157126)
24. R.A. Chen, and W.G. Goodman Role of the calcium-sensing receptor in parathyroid gland physiology Am J Renal Physiol 286 2004 F1005 F1011
25. S. Steddon, and J. Cunningham Calcimimetics and calcilytics fooling the calcium receptor Lancet 365 2005 2237 2239 (Pubitemid 40853917)
26. E.F. Nemeth, W.H. Heaton, M. Miller, J. Fox, M.F. Balandrin, and B.C. Van Wagenen Pharmacodynamics of the type II calcimimetic compound cinacalcet HCI J Pharmacol Exp Ther 308 2004 627 635 (Pubitemid 38134225)
27. C.J. Diskin, T.J. Strkes, L.M. Dansby, L. Radcliff, and T.B. Carter Can acidosis and hyperphostaemia result in increased erythropoietin dosing in haemodialysis patients Nephrology 11 2006 394 399 (Pubitemid 44470086)
28. E. Parra, R. Ramos, A. Betriu, J. Panianga, M. Belart, and T. Martinez Effect of a quality improvement strategy on several haemodialysis outcomes Nephrol Dial Transplant 23 2008 2943 2947
29. Lam BS, Cunningham C, Adams GB. Pharmacologic modulation of the calcium-sensing receptor enhaces hematopoietic stem cell lodgement in the adult bone marrow. Blood 2011;117(4):1167-75.
30. B. Di Iorio, M. Cirillo, V. Bellizi, D. Stellato, N.G. De Santo Campania dialysis registry research group Prevalence and correlates of anemia and uncontrolled anemia in chronic hemodialysis patients-The Campania Dialysis Regisrty Int J Artif Organs 30 2007 325 333 (Pubitemid 46938857)
31. S. Anaya, F. Rivera, M.D. Sanchez de la Nieta, A. Carreño, C. Vozmediano, and M.P. Alcaide Comorbidity, anemia and response to erythropoiesis stimulating agents in chronic hemodialysis Nefrologia 28 2008 186 192
32. J. Cunningham, M. Danese, K. Olson, P. Klassen, and G.M. Chertow Effects of the calcimimetic cinacalcet HCL on cardiovascular disease, fracture, and health-related quality of life in secondary hyperparathyroidism Kidney Int 68 2005 1793 1800 (Pubitemid 43169924)
33. W.G. Goodman Calcium-sensing receptors Sem Nephrol 24 2004 17 24 (Pubitemid 38141841)
34. S.C. Hebert Therapeutic use of calcimimetics Annu Rev Med 57 2006 349 364 (Pubitemid 43261995)
35. R. Perez-Garcia, P. Rodriguez Benitez, R. Jofre, J.M. Lopez-Gomez, M.T. Villaverde, and A. Blanco Resistance index to epoetin alpha and to darbepoetin-alpha in chronic hemodialysis patients: a cohort study Nefrologia 27 2007 340 349