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Volumn 76, Issue 14, 2011, Pages 5719-5731
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Synthesis and preliminary evaluation of pro-RNA 2′- O -masked with biolabile pivaloyloxymethyl groups in an RNA interference assay
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Author keywords
[No Author keywords available]
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Indexed keywords
CELLULAR DELIVERY;
CELLULAR UPTAKE;
DELIVERY PROBLEMS;
DEPROTECTION;
FLUORIDE ION;
HUMAN CELLS;
NUCLEOBASES;
OLIGORIBONUCLEOTIDES;
PHARMACEUTICAL APPLICATIONS;
PRODRUGS;
RNA INTERFERENCE;
SMALL INTERFERING RNA (SIRNA);
ANIMAL CELL CULTURE;
RNA;
ACID;
BASE;
FLUORIDE;
HYDROXIDE;
METHYL GROUP;
NUCLEIC ACID BASE;
OLIGORIBONUCLEOTIDE;
PIVALOYLOXYMETHYL GROUP;
PRODRUG;
RNA PRODRUG;
SMALL INTERFERING RNA;
UNCLASSIFIED DRUG;
ARTICLE;
CELL CULTURE;
CELL TRANSPORT;
CHEMICAL MODIFICATION;
CONTROLLED STUDY;
CROSS LINKING;
DEPROTECTION REACTION;
DRUG DELIVERY SYSTEM;
DRUG RELEASE;
ENZYME RELEASE;
HUMAN;
HUMAN CELL;
MOLECULAR STABILITY;
PURIFICATION;
RNA INTERFERENCE;
SYNTHESIS;
CELLS, CULTURED;
HUMANS;
MOLECULAR STRUCTURE;
OLIGORIBONUCLEOTIDES;
RNA, SMALL INTERFERING;
STEREOISOMERISM;
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EID: 79960152506
PISSN: 00223263
EISSN: 15206904
Source Type: Journal
DOI: 10.1021/jo200826h Document Type: Article |
Times cited : (26)
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References (25)
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