In vitro and in vivo evaluation of an intraocular implant for glaucoma treatment

International Journal of Pharmaceutics

Volumn 415, Issue 1-2, 2011, Pages 73-82

  Natu, Mâdâlina V ^a   Gaspar, Manuel N ^a   Fontes Ribeiro, Carlos A ^a   Cabrita, António M ^a   De Sousa, Hermínio C ^a   Gil, M H ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Controlled drug release; Glaucoma; In vivo; Intraocular pressure; Poly( caprolactone); Subconjunctival implant

Indexed keywords

DORZOLAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTACT ANGLE; CONTROLLED STUDY; CRYSTALLIZATION; DRUG RELEASE; EXPERIMENTAL RABBIT; FOREIGN BODY REACTION; GLAUCOMA; HISTOPATHOLOGY; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; INTRAOCULAR PRESSURE; LENS IMPLANT; MELTING POINT; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIHYPERTENSIVE AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG CARRIERS; DRUG IMPLANTS; EYE; GLAUCOMA; INTRAOCULAR PRESSURE; KINETICS; MICROSCOPY, ELECTRON, SCANNING; POLYESTERS; POLYETHYLENE GLYCOLS; PROPYLENE GLYCOLS; RABBITS; SOLUBILITY; SULFONAMIDES; SURFACE PROPERTIES; THIOPHENES;

EID: 79960152295     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.05.047     Document Type: Article

References (26)

1. J.L. Bourges, C. Bloquel, A. Thomas, F. Froussart, A. Bochot, F. Azan, R. Gurny, D. BenEzra, and F. Behar-Cohen Intraocular implants for extended drug delivery: therapeutic applications Adv. Drug. Deliv. Rev. 2006 10.1016/j.addr.2006.07.026 (Pubitemid 44794429)
2. J. Breitenbach Melt extrusion: from process to drug delivery technology Eur. J. Pharm. Biopharm. 54 2002 107 117 (Pubitemid 34919382)
3. E.M. del Amo, and A. Urtti Current and future ophthalmic drug delivery systems A shift to the posterior segment Drug Discov. Today 2008 10.1016/j.drudis.2007.11.002
4. A. Harris, O. Arend, H.S. Chung, L. Kagemann, L. Cantor, and B. Martin A comparative study of betaxolol and dorzolamide effect on ocular circulation in normal-tension glaucoma patients Ophthalmology 107 2000 430 434 (Pubitemid 30191361)
5. P.T. Khaw, P. Shah, and A.R. Elkington Glaucoma-2: treatment Br. Med. J. 2004 10.1136/bmj.328.7432.156
6. A.G. Konstas, V.P. Kozobolis, S. Tsironi, I. Makridaki, R. Efremova, and W.C. Stewart Comparison of the 24-hour intraocular pressure-lowering effects of latanoprost and dorzolamide/timolol fixed combination after 2 and 6 months of treatment Ophthalmology 2008 10.1016/j.ophtha.2007.03.007 (Pubitemid 350309407)
7. J.M. Korte, T. Kaila, and K.M. Saari Systemic bioavailability and cardiopulmonary effects of 0.5% timolol eyedrops Graefes Arch. Clin. Exp. Ophthalmol. 2002 10.1007/s00417-002-0462-2 (Pubitemid 36097063)
8. S.V. Kulkarni, K.F. Damji, and Y.M. Buys Medical management of primary open-angle glaucoma: Best practices associated with enhanced patient compliance and persistency Patient Prefer. Adherence 2 2008 303 313
9. N. Kuno, and S. Fujii Biodegradable intraocular therapies for retinal disorders: progress to date Drugs Aging 27 2010 117 134 10.2165/11530970- 000000000-00000
10. H. Levkovitch-Verbin, H.A. Quigley, K.R.G. Martin, D. Valenta, L.A. Baumrind, and M.E. Pease Translimbal laser photocoagulation to the trabecular meshwork as a model of glaucoma in rats Invest. Ophthalmol. Vis. Sci. 43 2002 402 410 (Pubitemid 34113222)
11. K.L. Macoul, and D. Pavan-Langston Pilocarpine ocusert system for sustained control of ocular hypertension Arch. Ophthalmol. 93 1975 587 590
12. M. Miyajima, A. Koshika, J. Okada, M. Ikeda, and K. Nishimura Effect of polymer crystallinity on papaverine release from poly(l-lactic acid) matrix J. Control. Release 1997 10.1016/S0168-3659(97)00081-3 (Pubitemid 28020274)
13. B.K. Nanjawade, F.V. Manvi, and A.S. Manjappa In situ-forming hydrogels for sustained ophthalmic drug delivery J. Control. Release 2007 10.1016/j.jconrel.2007.07.009 (Pubitemid 47361409)
14. M.V. Natu, M.H. Gil, and H.C. de Sousa Supercritical solvent impregnation of poly(ε-caprolactone)/poly(oxyethylene-b-oxypropylene-b-oxyethylene) and poly(ε-caprolactone)/poly(ethylene-vinyl acetate) blends for controlled release applications J. Supercrit. Fluids 2008 10.1016/j.supflu.2008.05.006
15. M.V. Natu, H.C. de Sousa, and M.H. Gil Effects of drug solubility, state and loading on controlled release in bicomponent electrospun fibers Int. J. Pharm. 2010 10.1016/j.ijpharm.2010.06.045
16. M.V. Natu, M.N. Gaspar, C.A.F. Ribeiro, I.J. Correia, D. Silva, H.C. de Sousa, and M.H. Gil A poly(ε-caprolactone) device for sustained release of an anti-glaucoma drug Biomed. Mater. 6 2011 025003 10.1088/1748-6041/6/2/025003
17. R.J. Noecker Evaluation of bimatoprost 0.03% versus latanoprost 0.005%: a paired comparison study Invest. Ophthalmol. Vis. Sci. 46 2005 E-Abstract 2452
18. C.G. Pitt, F.I. Chasalow, Y.M. Hibionada, D.M. Klimas, and A. Schindler Aliphatic polyesters. I. The degradation of poly(ε-caprolactone) in vivo J. Appl. Polym. Sci. 1981 10.1002/app.1981.070261124 (Pubitemid 12454836)
19. H.A. Quigley Glaucoma: macrocosm to microcosm Invest. Ophthalmol. Vis. Sci. 2005 10.1167/iovs.041070
20. J. Ruiz-Ederra, and A.S. Verkman Mouse model of sustained elevation in intraocular pressure produced by episcleral vein occlusion Exp. Eye Res. 2006 10.1016/j.exer.2005.10.019 (Pubitemid 43170889)
21. K. Schmitz, P. Banditt, M. Motschmann, F.P. Meyer, and W. Behrens-Baumann Population pharmacokinetics of 2% topical dorzolamide in the aqueous humor of humans Invest. Ophthalmol. Vis. Sci. 40 1999 1621 1624 (Pubitemid 29252357)
22. K. Schwartz, and D. Budenz Current management of glaucoma Curr. Opin. Ophthalmol. 15 2004 119 126 (Pubitemid 38457131)
23. A. Scozzafava, L. Menabuoni, F. Mincione, F. Briganti, G. Mincione, and C.T. Supuran Carbonic anhydrase inhibitors. synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? J. Med. Chem. 1999 10.1021/jm9900523 (Pubitemid 29344304)
24. M. Seki, T. Tanaka, H. Matsuda, T. Togano, K. Hashimoto, J. Ueda, T. Fukuchi, and H. Abe Topically administered timolol and dorzolamide reduce intraocular pressure and protect retinal ganglion cells in a rat experimental glaucoma model Br. J. Ophthalmol. 2005 10.1136/bjo.2004.052860 (Pubitemid 40469975)
25. T. Yasukawa, Y. Ogura, E. Sakurai, Y. Tabata, and H. Kimura Intraocular sustained drug delivery using implantable polymeric devices Adv. Drug Deliv. Rev. 57 2005 2033 2046 10.1016/j.addr.2005.09.005 (Pubitemid 41740794)
26. Yudcovitch, L. Pharmaceutical, laser and surgical treatments for glaucoma: an update. http://www.pacificu.edu/optometry/ce/courses/15166/ pharglapg2.cfm#Pharmaceutical (accessed 15.10.10).