A poly(ε-caprolactone) device for sustained release of an anti-glaucoma drug

Biomedical Materials

Volumn 6, Issue 2, 2011, Pages

  Natu, Mǎdǎlina V ^a   Gaspar, Manuel N ^a   Ribeiro, Carlos A Fontes ^a   Correia, Ilídio J ^b   Silva, Daniela ^b   De Sousa, Hermínio C ^a   Gil, M H ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF BEIRA INTERIOR   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

BLENDING; CYTOTOXICITY; DEGRADATION; DIFFUSION; DRUG PRODUCTS; ENDOTHELIAL CELLS; ETHYLENE; POLYETHYLENE OXIDES; POLYMERS; PROPYLENE; REGRESSION ANALYSIS;

BURST RELEASE; CAPROLACTONE; COATED SAMPLE; CONTROLLED RELEASE; CRYSTALLINITIES; CYTOTOXIC; DEGRADATION MODEL; DORZOLAMIDE; DRUG RELEASE; IN-VITRO; INTRA OCULAR PRESSURE; MASS LOSS; NON-LINEAR REGRESSION ANALYSIS; POLYMER DEGRADATION; PURE POLYMERS; RABBIT EYES; RELEASE MECHANISM; SUSTAINED RELEASE; WATER UPTAKE;

PLASTIC COATINGS;

DORZOLAMIDE; MACROGOL; POLY(ETHYLENE OXIDE)BETA POLY(PROPYLENE OXIDE)BETA POLY(ETHYLENE OXIDE); POLYCAPROLACTONE; UNCLASSIFIED DRUG; ANTIHYPERTENSIVE AGENT; BIOMATERIAL; POLYESTER; POLYMER; SULFONAMIDE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; THIOPHENE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCOMPATIBILITY; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CORNEA ENDOTHELIUM; DEVICE; DRUG COATING; DRUG DEGRADATION; DRUG DIFFUSION; ENDOTHELIUM CELL; FEMALE; GLAUCOMA; INTRAOCULAR PRESSURE; MALE; NONHUMAN; OPTIC DISK; RABBIT; SUSTAINED DRUG RELEASE; TABLET POROSITY; ANIMAL; CHEMISTRY; CORNEA; DELAYED RELEASE FORMULATION; DIFFERENTIAL SCANNING CALORIMETRY; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG EFFECT; POROSITY; REGRESSION ANALYSIS; X RAY DIFFRACTION;

ORYCTOLAGUS CUNICULUS;

ANIMALS; ANTIHYPERTENSIVE AGENTS; BIOCOMPATIBLE MATERIALS; CALORIMETRY, DIFFERENTIAL SCANNING; CORNEA; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG DELIVERY SYSTEMS; GLAUCOMA; POLYESTERS; POLYMERS; POROSITY; RABBITS; REGRESSION ANALYSIS; SULFONAMIDES; TETRAZOLIUM SALTS; THIAZOLES; THIOPHENES; X-RAY DIFFRACTION;

EID: 79953723159     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/6/2/025003     Document Type: Article

References (47)

1. Quigley H A 2005 Glaucoma: macrocosm to microcosm Invest. Ophthalmol. Vis. Sci. 46 2663-70
2. Schwartz K and Budenz D 2004 Current management of glaucoma Curr. Opin. Ophthalmol. 15 119-26
3. Khaw P T, Shah P and Elkington A R 2004 Glaucoma: 2. Treatment Br. Med. 328 156-8
4. del Amo E M and Urtti A 2008 Current and future ophthalmic drug delivery systems. A shift to the posterior segment Drug Discovery Today 13 135-43
5. Korte J M, Kaila T and Saari K M 2002 Systemic bioavailability and cardiopulmonary effects of 0.5% timolol eyedrops Graefes Arch. Clin. Exp. Ophthalmol. 240 430-5
6. Noecker R J 2005 Evaluation of Bimatoprost 0.03% versus Latanoprost 0.005%: a paired comparison study Invest. Ophthalmol. Vis. Sci. 46 2452
7. Kulkarni S V, Damji K F and Buys Y M 2008 Medical management of primary open-angle glaucoma: best practices associated with enhanced patient compliance and persistency Patient Pref. Adherence 2 303-13
8. Bourges J L, Bloquel C, Thomas A, Froussart F, Bochot A, Azan F, Gurny R, BenEzra D and Behar-Cohen F 2006 Intraocular implants for extended drug delivery: therapeutic applications Adv. Drug Deliv. Rev. 58 1182-202
9. Nanjawade B K, Manvi F V and Manjappa A S 2007 In situ-forming hydrogels for sustained ophthalmic drug delivery J. Control. Release 122 119-34
10. Costa V P, Braga M E M, Duarte C M M, Alvarez-Lorenzo C, Concheiro A, Gil M H and de Sousa H C 2010 Anti-glaucoma drug-loaded contact lenses prepared using supercritical solvent impregnation J. Supercrit. Fluids 53 165-73
11. Hiratani H, Fujiwara A, Tamiya Y, Mizutani Y and Alvarez-Lorenzo C 2005 Ocular release of timolol from molecularly imprinted soft contact lenses Biomaterials 26 1293-8
12. Ludwig A 2005 The use of mucoadhesive polymers in ocular drug delivery Adv. Drug Deliv. Rev. 57 1593-639
13. Natu M V, Sardinha J P, Correia I J and Gil M H 2007 Controlled release gelatin hydrogels and lyophilisates with potential application as ocular inserts Biomed. Mater. 2 241-9 (Pubitemid 350215865)
14. Anumolu S S, Singh Y, Gao D, Stein S and Sink P J 2009 Design and evaluation of novel fast forming pilocarpine-loaded ocular hydrogels for sustained pharmacological response J. Control. Release 137 152-9
15. Barbu E, Verestiuc L, Iancu M, Jatariu A, Lungu A and Tsibouklis J 2009 Hybrid polymeric hydrogels for ocular drug delivery: nanoparticulate systems from copolymers of acrylic acid-functionalized chitosan and N- isopropylacrylamide or 2-hydroxyethyl methacrylate Nanotechnology 20 225108
16. Marchal-Heussler L, Sirbat D, Hoffman M and Maincent P 1993 Poly(ε-caprolactone) nanocapsules in carteolol ophthalmic delivery Pharm. Res. 10 386-90 (Pubitemid 23080602)
17. Kaur I P, Garg A, Singla A K and Aggarwal D 2004 Vesicular systems in ocular drug delivery: an overview Int. J. Pharm. 269 1-14 (Pubitemid 38035207)
18. Zimmer A and Kreuter J 1995 Microspheres and nanoparticles used in ocular delivery systems Adv. Drug Deliv. Rev. 16 61-73
19. Kashanian S et al 2010 Evaluation of mesoporous silicon/polycaprolactone composites as ophthalmic implants Acta Biomater. 6 3566-72
20. Macoul K L and Pavan Langston D 1975 Pilocarpine ocusert system for sustained control of ocular hypertension Arch. Ophthalmol. 93 587-90
21. Gurtler F, Kaltsatos V, Boisram B and Gurny R 1995 Long-acting soluble bioadhesive ophthalmic drug insert (BODI) containing gentamicin for veterinary use: optimization and clinical investigation J. Contol. Release 33 231-6
22. Pijls R T, Cruysberg L P J, Nuijts R M M A, Dias A A and Koole L H 2007 Capacity and tolerance of a new device for ocular drug delivery Int. J. Pharm. 341 152-61 (Pubitemid 47088118)
23. Sasaki H, Nagano T, Sakanaka K, Kawakami S, Nishida K, Nakamura J, Ichikawa N, Iwashita J, Nakamura T and Nakashima M 2003 One-side coated insert as a unique ophthalmic drug delivery system J. Control. Release 92 241-7 (Pubitemid 38366147)
24. Huang X and Brazel C S 2001 On the importance and mechanisms of burst release in matrix-controlled drug delivery systems J. Control. Release 73 121-36 (Pubitemid 32539245)
25. Natu M V, de Sousa H C and Gil M H 2010 Effects of drug solubility, state and loading on controlled release in bicomponent electrospun fibers Int. J. Pharm. 397 50-8
26. Natu M V, Gil M H and de Sousa H C 2008 Supercritical solvent impregnation of poly(ε-caprolactone)/poly(oxyethylene-b-oxypropylene- boxyethylene) and poly(ε-caprolactone)/poly(ethylene-vinyl acetate) blends for controlled release applications J. Supercrit. Fluids 47 93-102
27. Shen Y, Sun W, Zhu K J and Shen Z 2000 Regulation of biodegradability and drug release behavior of aliphatic polyesters by blending J. Biomed. Mater. Res. 50 528-35
28. Lyu S-P, Sparer R, Hobot C and Dang K 2005 Adjusting drug diffusivity using miscible polymer blends J. Control. Release 102 679-87 (Pubitemid 40170210)
29. Cao J and Billows C A 1999 Crystallinity determination of native and stretched wool by x-ray diffraction Polym. Int. 48 1027-33
30. ATHAS data bank, http://athas.prz.edu.pl/Default.aspx?op=db (accessed 9 March 2010)
31. Peppas N A and Brannon-Peppas L 1994 Water diffusion and sorption in amorphous macromolecular systems and foods J. Food Eng. 22 189-210
32. Tzafriri A R 2000 Mathematical modeling of diffusion-mediated release from bulk degrading matrices J. Control. Release 63 69-79 (Pubitemid 30046943)
33. Council Directive 86/609/EEC of 24 November 1986 on the approximation of laws, regulations and administrative provisions of the Member States regarding the protection of animals used for experimental and other scientific purposes, http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:31986L0609:en:HTML (accessed 6 April 2010)
34. Commission recommendation of 18 June 2007 on guidelines for the accommodation and care of animals used for experimental and other scientific purposes, http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2007:197: 0001:0089:EN:PDF (accessed 6 April 2010)
35. http://www.openoffice.org/ (accessed 5 August 2010)
36. Chen C-C, Chueh J-Y, Tseng H, Huang H-M and Lee S-Y 2003 Preparation and characterization of biodegradable PLA polymeric blends Biomaterials 24 1167-73
37. Ajili S H and Ebrahimi N G 2007 Miscibility of TPU(PCL diol)/PCL blend and its effect on PCL crystallinity Macromol. Symp. 249-250 623-7 (Pubitemid 47119084)
38. Tsuji H and Ikada Y 1996 Blends of aliphatic polyesters: I. Physical properties and morphologies of solution-cast blends from poly(DL-lactide) and poly(ε-caprolactone) J. Appl. Polym. Sci. 60 2367-75
39. Ha J C, Kim S Y and Lee Y M 1999 Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (pluronic)/poly(ε-caprolactone) (PCL) amphiphilic block copolymeric nanospheres: I. Preparation and characterization J. Control. Release 62 381-92
40. Qiu Z, Ikehara T and Nishi T 2003 Miscibility and crystallization of poly(ethylene oxide) and poly(ε-caprolactone) blends Polymer 44 3101-6 (Pubitemid 36460370)
41. Grizzi I, Garreau H, Li S and Vert M 1995 Hydrolytic degradation of devices based on poly(DL-lactic acid) size dependence Biomaterials 16 305-11
42. Hglund A, Hakkarainen M and Albertsson A-C 2007 Degradation profile of poly(ε-caprolactone) - the influence of macroscopic and macromolecular biomaterial design J. Macromol. Sci. A 44 1041-6
43. Loo S C J, Ooi C P, Wee S H E and Boey Y C F 2005 Effect of isothermal annealing on the hydrolytic degradation rate of poly(lactide co-glycolide) (PLGA) Biomaterials 26 2827-33 (Pubitemid 39647222)
44. Tiwari S K, Tzezana R, Zussman E and Venkatraman S S 2010 Optimizing partition-controlled drug release from electrospun core-shell fibers Int. J. Pharm. 392 209-17
45. Yudcovitch L 2010 Pharmaceutical, laser and surgical treatments for glaucoma: an update, http://www.pacificu.edu/optometry/ce/courses/15166/ pharglapg2.cfm#Pharmaceutical (accessed 23 July 2010)
46. Harris A, Arend O, Chung H S, Kagemann L, Cantor L and Martin B 2000 A comparative study of betaxolol and dorzolamide effect on ocular circulation in normal-tension glaucoma patients Ophthalmology 107 430-4
47. Scozzafava A, Menabuoni L, Mincione F, Briganti F, Mincione G and Supuran C T 1999 Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? J. Med. Chem. 42 2641-50