Zebrafish assessment of cognitive improvement and anxiolysis: Filling the gap between in vitro and rodent models for drug development

Reviews in the Neurosciences

Volumn 22, Issue 1, 2011, Pages 75-84

  Levin, Edward D ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anxiety; Buspirone; Diazepam; Learning; Memory; Nicotine; Zebrafish

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; BUSPIRONE; CHLORDIAZEPOXIDE; DIAZEPAM; MECAMYLAMINE; NICOTINE; NICOTINE TARTRATE; ANXIOLYTIC AGENT; NICOTINIC AGENT; NICOTINIC RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; COGNITION; CONTROLLED STUDY; DISCRIMINATION LEARNING; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; EXPERIMENTAL MODEL; EXPERIMENTAL TEST; IN VITRO STUDY; LOW DRUG DOSE; NEUROLOGIC EXAMINATION; NONHUMAN; PHARMACOLOGICAL PARAMETERS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RODENT; SPATIAL DISCRIMINATION; SPATIAL MEMORY; STRESS; TANK DIVING TEST; TASK PERFORMANCE; TRANQUILIZING ACTIVITY; VALIDITY; WORKING MEMORY; ZEBRA FISH; ANIMAL; ANXIETY; ATTENTION; DEPTH PERCEPTION; DISEASE MODEL; DRUG DESIGN; DRUG SCREENING; EXPLORATORY BEHAVIOR; METHODOLOGY; NEUROCHEMISTRY; TIME;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; ATTENTION; BUSPIRONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; EXPLORATORY BEHAVIOR; MECAMYLAMINE; NEUROCHEMISTRY; NICOTINE; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; SPACE PERCEPTION; TIME FACTORS; ZEBRAFISH;

EID: 79960125913     PISSN: 03341763     EISSN: None     Source Type: Journal    
DOI: 10.1515/RNS.2011.009     Document Type: Article

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