Identification of new cases of early-onset colorectal cancer with an MLH1 epimutation in an ethnically diverse South African cohort

Clinical Genetics

Volumn 80, Issue 5, 2011, Pages 428-434

  Hitchins, Mp ^a   Owens, Se ^b   Kwok, C T ^a   Godsmark, G ^b   Algar, Uf ^b   Ramesar, Rs ^b  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Colorectal cancer; Epimutation; Lynch syndrome; MLH1

Indexed keywords

CELL DNA; MYOD PROTEIN; PROTEIN MLH1;

ADULT; ALLELE; ARTICLE; ASIAN; CANCER SUSCEPTIBILITY; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DNA METHYLATION; EARLY CANCER; ETHNIC DIFFERENCE; FEMALE; GENE IDENTIFICATION; GENE MUTATION; GENETIC PREDISPOSITION; GENETIC SCREENING; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HUMAN; INDIAN; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MISMATCH REPAIR; MOSAICISM; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOUTH AFRICA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA METHYLATION; DNA MISMATCH REPAIR; ETHNIC GROUPS; FEMALE; HUMANS; MALE; MIDDLE AGED; MUTATION; NUCLEAR PROTEINS; SOUTH AFRICA;

EID: 79960123568     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2011.01660.x     Document Type: Article

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