Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Takeda, Kojiro ^a   Mori, Ayaka ^a   Yanagida, Mitsuhiro ^a  

^a OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; BORTEZOMIB; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 13; HISTONE H2A; PROTEASOME; PROTEIN RPN12; REGULATOR PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BORONIC ACID DERIVATIVE; PYRAZINE DERIVATIVE;

ARTICLE; CHROMOSOME SEGREGATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG SENSITIVITY; GENE DELETION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC CONSERVATION; GENETIC SCREENING; LETHALITY; MITOSIS INHIBITION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHARMACOLOGICAL BLOCKING; SCHIZOSACCHAROMYCES POMBE; BIOLOGICAL MODEL; CYTOLOGY; DRUG EFFECT; FUNGAL GENE; GENETICS; METABOLISM; METAPHASE; MITOSIS; MUTATION; SCHIZOSACCHAROMYCES;

SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE;

ANTINEOPLASTIC AGENTS; BORONIC ACIDS; CHROMOSOME SEGREGATION; GENES, FUNGAL; GENETIC TESTING; METAPHASE; MITOSIS; MODELS, BIOLOGICAL; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PYRAZINES; SCHIZOSACCHAROMYCES;

EID: 79960105001     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0022021     Document Type: Article

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