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Volumn 4, Issue 3, 2011, Pages 13-17

Amla - The role of ayurvedic therapeutic herb in cancer

Author keywords

Anticarcinogenic; Antitumor activity; Chemoprevention; Medicinal herb; Phyllanthus emblica

Indexed keywords

ANTINEOPLASTIC AGENT; ELLAGIC ACID; EMBLICA OFFICINALIS EXTRACT; FEBRIFUGE; GALLIC ACID; GLYCOSIDE; HERBACEOUS AGENT; PHENOL DERIVATIVE; POLYPHENOL DERIVATIVE; TANNIN DERIVATIVE; TRIPHALA; UNCLASSIFIED DRUG;

EID: 79960099094     PISSN: 09742441     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (17)

References (67)
  • 2
    • 84957940642 scopus 로고    scopus 로고
    • World Health Organisation
    • World Health Organisation: Cancer, 2006.
    • (2006) Cancer
  • 3
    • 0026425585 scopus 로고
    • Chemical and physical carcinogenesis: Advances and perspectives for the 1990s
    • Harris CC. Chemical and physical carcinogenesis: advances and perspectives for the 1990s. Cancer Res 1991; 5 Suppl: 5023-5044.
    • (1991) Cancer Res , vol.5 , Issue.SUPPL , pp. 5023-5044
    • Harris, C.C.1
  • 5
    • 27744575798 scopus 로고    scopus 로고
    • Chemoprevention: A primary cancer prevention strategy
    • Smith JJ, Tully P, Padberg RM. Chemoprevention: a primary cancer prevention strategy. Semin Oncol Nurs 2005; 21: 243-251.
    • (2005) Semin Oncol Nurs , vol.21 , pp. 243-251
    • Smith, J.J.1    Tully, P.2    Padberg, R.M.3
  • 6
    • 27644477094 scopus 로고    scopus 로고
    • Cancer chemoprevention: Scientific promise, clinical uncertainty
    • Sporn MB, Liby KT. Cancer chemoprevention: scientific promise, clinical uncertainty. Nat Clin Pract Oncol 2005; 2: 518-525.
    • (2005) Nat Clin Pract Oncol , vol.2 , pp. 518-525
    • Sporn, M.B.1    Liby, K.T.2
  • 7
    • 27144509730 scopus 로고    scopus 로고
    • Cancer chemoprevention: Lessons learned and future directions
    • Brenner DE, Gescher AJ. Cancer chemoprevention: lessons learned and future directions. Br J Cancer 2005; 93: 735-739.
    • (2005) Br J Cancer , vol.93 , pp. 735-739
    • Brenner, D.E.1    Gescher, A.J.2
  • 8
    • 15944395705 scopus 로고    scopus 로고
    • The current state of cancer chemoprevention
    • Kim ES, Hong WK. The current state of cancer chemoprevention. J Natl Cancer Inst 2005; 97: 468-470.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 468-470
    • Kim, E.S.1    Hong, W.K.2
  • 9
    • 0028346953 scopus 로고
    • Progress in cancer chemoprevention: Perspectives on agent selection and short-term clinical intervention trials
    • Kelloff GJ, Boone CW, Steele VE, Crowell JA, Lubet R, Sigman CC. Progress in cancer chemoprevention: perspectives on agent selection and short-term clinical intervention trials. Cancer Res 1994; 54: 2015-2024.
    • (1994) Cancer Res , vol.54 , pp. 2015-2024
    • Kelloff, G.J.1    Boone, C.W.2    Steele, V.E.3    Crowell, J.A.4    Lubet, R.5    Sigman, C.C.6
  • 10
    • 0022261651 scopus 로고
    • Carcinogenicity and modification of the carcinogenic response by BHA, BHT, and other antioxidants
    • Ito, N., Fukushima, S. and Tsuda, H., Carcinogenicity and modification of the carcinogenic response by BHA, BHT, and other antioxidants. Crit Rev Toxicol 1985; 15: 109-150.
    • (1985) Crit Rev Toxicol , vol.15 , pp. 109-150
    • Ito, N.1    Fukushima, S.2    Tsuda, H.3
  • 11
    • 85053990599 scopus 로고
    • Traditional remedies and modern assessment: The case of ginseng
    • Wijesekera, ROB, editors, Florida, CRC Press
    • Hikino H. Traditional remedies and modern assessment: the case of ginseng. In: Wijesekera, ROB, editors. The Medicinal Plant Industry 2nd ed. Boca Raton, Florida, CRC Press, 1991. pp. 149-166.
    • (1991) The Medicinal Plant Industry 2nd Ed. Boca Raton , pp. 149-166
    • Hikino, H.1
  • 13
    • 0032543420 scopus 로고    scopus 로고
    • Chemopreventive properties of some pungent ingredients present in red pepper and ginger
    • Surh YJ, Lee E, Lee JM. Chemopreventive properties of some pungent ingredients present in red pepper and ginger. Mutation Res 1998; 402: 259-267.
    • (1998) Mutation Res , vol.402 , pp. 259-267
    • Surh, Y.J.1    Lee, E.2    Lee, J.M.3
  • 14
    • 0036279287 scopus 로고    scopus 로고
    • Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: A short review
    • Surh YJ. Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review. Food Chem Toxicol 2002;40: 1091-1097.
    • (2002) Food Chem Toxicol , vol.40 , pp. 1091-1097
    • Surh, Y.J.1
  • 16
    • 18744374705 scopus 로고
    • Safety of herbal drugs-an overview
    • Siddiqui HH. Safety of herbal drugs-an overview. Drugs News and Views 1993; 1: 7-10.
    • (1993) Drugs News and Views , vol.1 , pp. 7-10
    • Siddiqui, H.H.1
  • 18
    • 0034635858 scopus 로고    scopus 로고
    • Phyllaemblic acid, a novel highly oxygenated norbisabolane from the roots of Phyllanthus emblica
    • Zhang Y, Tanaka T, Iwamoto Y, Yang C, Kouno I. Phyllaemblic acid, a novel highly oxygenated norbisabolane from the roots of Phyllanthus emblica. Tetrahedron Lett 2000; 41: 1781-1784.
    • (2000) Tetrahedron Lett , vol.41 , pp. 1781-1784
    • Zhang, Y.1    Tanaka, T.2    Iwamoto, Y.3    Yang, C.4    Kouno, I.5
  • 19
    • 4544256042 scopus 로고    scopus 로고
    • Evaluation of anti-pyretic and analgesic activity of Emblica officinalis Gaertn
    • Peryanayagam J, Sharma S, Joseph A, Christina A. Evaluation of anti-pyretic and analgesic activity of Emblica officinalis Gaertn. J Ethnopharmacol 2004; 95: 83-5.
    • (2004) J Ethnopharmacol , vol.95 , pp. 83-85
    • Peryanayagam, J.1    Sharma, S.2    Joseph, A.3    Christina, A.4
  • 20
    • 31444441067 scopus 로고    scopus 로고
    • Influence of Amla (Emblica officinalis Gaertn.) on hypercholesterolemia and lipid peroxidation in cholesterol-fed rats
    • Kim HJ, Yokozawa T, Kim HY, Tohda C, Rao TP, Juneja LR. Influence of Amla (Emblica officinalis Gaertn.) on hypercholesterolemia and lipid peroxidation in cholesterol-fed rats. J Nutr Sci Vitaminol 2005; 51: 413-418.
    • (2005) J Nutr Sci Vitaminol , vol.51 , pp. 413-418
    • Kim, H.J.1    Yokozawa, T.2    Kim, H.Y.3    Tohda, C.4    Rao, T.P.5    Juneja, L.R.6
  • 21
    • 0031401063 scopus 로고    scopus 로고
    • Antimutagenic and anticarcinogenic activity of Emblica officinalis Gaertn
    • Jeena KJ, Kuttan G, George J, Kuttan R. Antimutagenic and anticarcinogenic activity of Emblica officinalis Gaertn. J Clin Biochem Nutr 1996; 22: 171-176.
    • (1996) J Clin Biochem Nutr , vol.22 , pp. 171-176
    • Jeena, K.J.1    Kuttan, G.2    George, J.3    Kuttan, R.4
  • 22
    • 0035047879 scopus 로고    scopus 로고
    • Antitumour activity of Emblica officinalis
    • Jose JK, Kuttan G, Kuttan R. Antitumour activity of Emblica officinalis. J Ethnopharmacol 2001; 75: 65-69.
    • (2001) J Ethnopharmacol , vol.75 , pp. 65-69
    • Jose, J.K.1    Kuttan, G.2    Kuttan, R.3
  • 23
    • 0038714506 scopus 로고    scopus 로고
    • Induction of Apoptosis in Mouse and Human Carcinoma Cell Lines by Emblica officinalis Polyphenols and its Effect on Chemical Carcinogenesis
    • Rajeshkumar NV, Radahakrishna Pillai M, Kuttan R. Induction of Apoptosis in Mouse and Human Carcinoma Cell Lines by Emblica officinalis Polyphenols and its Effect on Chemical Carcinogenesis. J Exp Clin Cancer Res 2003; 22: 201-212.
    • (2003) J Exp Clin Cancer Res , vol.22 , pp. 201-212
    • Rajeshkumar, N.V.1    Radahakrishna, P.M.2    Kuttan, R.3
  • 24
    • 33646712885 scopus 로고    scopus 로고
    • Triphala - the wonder drug
    • Juss SS, Triphala - the wonder drug. Indian Med Gaz 1997; 131: 194-196.
    • (1997) Indian Med Gaz , vol.131 , pp. 194-196
    • Juss, S.S.1
  • 25
    • 79960098601 scopus 로고    scopus 로고
    • Available at
    • Available at http://www.toddcaldecott.com/amalaki.html.
  • 27
    • 0004109261 scopus 로고
    • His Majesty's Government of Nepal, Ministry of Forest and Soil Conservation, Department of Medicinal Plants, 3rd ed). His Majesty's Government Press, Kathmandu
    • His Majesty's Government of Nepal, Ministry of Forest and Soil Conservation, Department of Medicinal Plants. Medicinal Plants of Nepal (3rd ed). His Majesty's Government Press, Kathmandu, 1982, pp. 185.
    • (1982) Medicinal Plants of Nepal , pp. 185
  • 28
    • 0003914373 scopus 로고
    • (Indigenous and Exotic/Used in Ceylon. Part II. Government Press, Kathmandu
    • Jayaweera DMA. Medicinal Plants (Indigenous and Exotic/ Used in Ceylon. Part II. Government Press, Kathmandu, 1982, pp. 185.
    • (1982) Medicinal Plants , pp. 185
    • Jayaweera, D.M.A.1
  • 29
    • 79960107115 scopus 로고    scopus 로고
    • Personal communication: Uses of Phyllanthus species in traditional Thai medicine, translated from nine books in Thai
    • Bangkok
    • Bunyapraphatsara N. Personal communication: uses of Phyllanthus species in traditional Thai medicine, translated from nine books in Thai. Medicinal Plant Information Center,.Mahidol University, Bangkok.
    • Medicinal Plant Information Center, Mahidol University
    • Bunyapraphatsara, N.1
  • 33
    • 79960108978 scopus 로고
    • Die Heilpflunzen der Verschiedenen Viilker und Zeiten
    • Dragendorff, G., Die Heilpflunzen der Verschiedenen Viilker und Zeiten. Verlag von Ferdinand Enke, Stuttgart, 1898; pp. 373-374.
    • (1898) Verlag Von Ferdinand Enke, Stuttgart , pp. 373-374
    • Dragendorff, G.1
  • 35
    • 2742589144 scopus 로고    scopus 로고
    • Active constituent of Emblica officinalis: Part 1st the chemistry and antioxidant effects of two new hydrolysable tannins, emblicanin A and B
    • Ghosal S, Tripathi VK, Chauhan S. Active constituent of Emblica officinalis: part 1st the chemistry and antioxidant effects of two new hydrolysable tannins, emblicanin A and B. Indian J Chem. 1996; 35: 941-948.
    • (1996) Indian J Chem , vol.35 , pp. 941-948
    • Ghosal, S.1    Tripathi, V.K.2    Chauhan, S.3
  • 37
    • 0016738861 scopus 로고
    • Phyllantidine and phyllantine from Emblica officinalis Gaertn leafs fruits and in vitro tissue cultures
    • Khanna P, Bansal R. Phyllantidine and phyllantine from Emblica officinalis Gaertn leafs fruits and in vitro tissue cultures. Indian J Exp Biol 1975; 13: 82-83.
    • (1975) Indian J Exp Biol , vol.13 , pp. 82-83
    • Khanna, P.1    Bansal, R.2
  • 39
    • 36348938641 scopus 로고    scopus 로고
    • A new cytotoxic acylated apigenin glucoside from Phyllanthus emblica L
    • El-Desouky SK, Ryu SY, Kim YK. A new cytotoxic acylated apigenin glucoside from Phyllanthus emblica L. Nat Prod Res 2008; 22: 91-5.
    • (2008) Nat Prod Res , vol.22 , pp. 91-95
    • El-Desouky, S.K.1    Ryu, S.Y.2    Kim, Y.K.3
  • 42
    • 12944258222 scopus 로고    scopus 로고
    • Aonla: Potential fruit for processing
    • Jain SK, Khurdiya DS. Aonla: Potential fruit for processing. Delhi Garden Maga 2000; 38: 50-51.
    • (2000) Delhi Garden Maga , vol.38 , pp. 50-51
    • Jain, S.K.1    Khurdiya, D.S.2
  • 43
    • 0343224894 scopus 로고
    • Chemical analysis of the emblic (Phyllanthus emblica L.) and its potential as a food source
    • Barthakur NN, Arnold NP. Chemical analysis of the emblic (Phyllanthus emblica L.) and its potential as a food source. Scientia Horticult 1991, 47: 99-105.
    • (1991) Scientia Horticult , vol.47 , pp. 99-105
    • Barthakur, N.N.1    Arnold, N.P.2
  • 44
    • 77957269314 scopus 로고    scopus 로고
    • Antitumour effects of phyllanthus emblica L., Induction of cancer cell apoptosis and Inhibition of in vivotumour promotion and in vitro invasion of human cancer cells
    • Ngamkitidechakul C, Jaijoy K, Hansakul P, Soonthornchareonnon N, Sireeratawong S. Antitumour effects of phyllanthus emblica L., Induction of cancer cell apoptosis and Inhibition of in vivotumour promotion and in vitro invasion of human cancer cells. Phytotherapy Res 2010; 24: 1405-1413.
    • (2010) Phytotherapy Res , vol.24 , pp. 1405-1413
    • Ngamkitidechakul, C.1    Jaijoy, K.2    Hansakul, P.3    Soonthornchareonnon, N.4    Sireeratawong, S.5
  • 45
    • 0036654206 scopus 로고    scopus 로고
    • Identification of pyrogallol as an antiproliferative compound present in extracts from the medicinal plant Emblica officinalis: Effects on in vitro cell growth of human tumor cell lines
    • Khan MT, Lampronti I, Martello D, Bianchi N, Jabbar S, Choudhuri MS et al. Identification of pyrogallol as an antiproliferative compound present in extracts from the medicinal plant Emblica officinalis: effects on in vitro cell growth of human tumor cell lines. Intl J Oncol 2002; 21: 187-92.
    • (2002) Intl J Oncol , vol.21 , pp. 187-192
    • Khan, M.T.1    Lampronti, I.2    Martello, D.3    Bianchi, N.4    Jabbar, S.5    Choudhuri, M.S.6
  • 46
    • 0034745984 scopus 로고    scopus 로고
    • Limitations of the histopathological diagnosis and prognostic assessment of hepatocellular carcinoma
    • Quaglia A, Bhattacharya S, Dhillon AP. Limitations of the histopathological diagnosis and prognostic assessment of hepatocellular carcinoma. Histopathology 2001;38:167-174.
    • (2001) Histopathology , vol.38 , pp. 167-174
    • Quaglia, A.1    Bhattacharya, S.2    Dhillon, A.P.3
  • 47
    • 79960095729 scopus 로고
    • Overall Evaluations of Carcinogenicity, France: IARC Scientific Publishers
    • Overall Evaluations of Carcinogenicity: An Updating of IARCMonographs., Lyon, France: IARC Scientific Publishers., 1987, 1-42.
    • (1987) An Updating of IARCMonographs., Lyon , pp. 1-42
  • 49
    • 0032922351 scopus 로고    scopus 로고
    • Intervention studies on cancer
    • Young KJ, Lee PN. Intervention studies on cancer. Eur J Cancer Prev 1999; 8: 91-103.
    • (1999) Eur J Cancer Prev , vol.8 , pp. 91-103
    • Young, K.J.1    Lee, P.N.2
  • 50
    • 44149108886 scopus 로고    scopus 로고
    • Emblica officinalis and hepatocarcinogenesis: A chemopreventive study in Wistar rats
    • Sarwat Sultana, Salahuddin Ahmed and Tamanna Jahangir., Emblica officinalis and hepatocarcinogenesis: A chemopreventive study in Wistar rats. J Ethnopharmacol 2008; 118: 1-6.
    • (2008) J Ethnopharmacol , vol.118 , pp. 1-6
    • Sultana, S.1    Ahmed, S.2    Jahangir, T.3
  • 51
    • 33744600902 scopus 로고
    • Skin cancer (what you need to know about), National cancer Institute, NIH Publication no
    • Skin cancer (what you need to know about). National Institutes of Health, National cancer Institute, NIH Publication no. 1993, 94-1563.
    • (1993) National Institutes of Health , pp. 94-1563
  • 52
    • 79960102304 scopus 로고    scopus 로고
    • Facts on Skin Cancer
    • Facts on Skin Cancer. American Cancer Society Publication 99-200. Rev. 8/95, no. 2049.
    • (2049) American Cancer Society Publication , vol.8 , Issue.95 , pp. 99-200
  • 53
    • 79960104494 scopus 로고    scopus 로고
    • Cancer Facts & Figure, 96-300, no. 5008-96,
    • Cancer Facts & Figure. American Cancer Society Publication 96-300, no. 5008-96, 1996, p. 17.
    • (1996) American Cancer Society Publication , pp. 17
  • 54
    • 0028284693 scopus 로고
    • Nonmelanoma skin cancer in the United States:Incidence
    • Miller DL, Weinstock MA. Nonmelanoma skin cancer in the United States:incidence. J Am Acad Dermatol 1994; 30: 774-778.
    • (1994) J Am Acad Dermatol , vol.30 , pp. 774-778
    • Miller, D.L.1    Weinstock, M.A.2
  • 56
    • 24944487293 scopus 로고    scopus 로고
    • Chemopreventive action of emblica officinalis on skin carcinogenesis in mice
    • Garima Sancheti, Archana Jindal, Rimpu Kumari, Goyal. Chemopreventive Action of Emblica Officinalis on Skin Carcinogenesis in mice. Asian Pacific J Cancer Prev 2005; 6: 197-201.
    • (2005) Asian Pacific J Cancer Prev , vol.6 , pp. 197-201
    • Sancheti, G.1    Jindal, A.2    Kumari, R.G.3
  • 57
    • 33846681883 scopus 로고    scopus 로고
    • Modulating effect of Phyllanthus fruit extract against lead genotoxicity in germ cells of mice
    • Madhavi D, Rudrama Devi K, Kesava Rao K, Reddy PP. Modulating effect of Phyllanthus fruit extract against lead genotoxicity in germ cells of mice. J Envi Biol 2007;28: 115-117.
    • (2007) J Envi Biol , vol.28 , pp. 115-117
    • Madhavi, D.1    Rudrama, D.K.2    Kesava, R.K.3    Reddy, P.P.4
  • 58
    • 10344263362 scopus 로고    scopus 로고
    • Protective effect of Emblica officinalis ethanolic extract against 7,12- dimethylbenz(a) anthracene (DMBA) inducedgenotoxicity in Swiss albino mice
    • Banu SM, Selvendiran K, Singh JP, Sakthisekaran D. Protective effect of Emblica officinalis ethanolic extract against 7,12- dimethylbenz(a) anthracene (DMBA) inducedgenotoxicity in Swiss albino mice. Hum Exp Toxicol.2004; 23: 527-31.
    • (2004) Hum Exp Toxicol , vol.23 , pp. 527-531
    • Banu, S.M.1    Selvendiran, K.2    Singh, J.P.3    Sakthisekaran, D.4
  • 59
    • 0030657924 scopus 로고    scopus 로고
    • Dietary chemoprevention of clastogenic effects of 3,4-benzo(a)pyrene by Emblica officinalis Gaertn. fruit extract
    • Nandi P, Talukder G, Sharma A. Dietary chemoprevention of clastogenic effects of 3,4-benzo(a)pyrene by Emblica officinalis Gaertn. fruit extract. Br J Cancer 1997; 76: 1279-1283.
    • (1997) Br J Cancer , vol.76 , pp. 1279-1283
    • Nandi, P.1    Talukder, G.2    Sharma, A.3
  • 60
    • 0024624316 scopus 로고
    • Effect of Emblica officinalis Gaertn. (Indian gooseberry) fruit extract on sodium azide and 4-nitro-ophenylenediamine induced mutagenesis in Salmonella typhimurium
    • Grover IS, Kaur S. Effect of Emblica officinalis Gaertn. (Indian gooseberry) fruit extract on sodium azide and 4-nitro-ophenylenediamine induced mutagenesis in Salmonella typhimurium. Indian J Exp Biol 1989; 27: 207-9.
    • (1989) Indian J Exp Biol , vol.27 , pp. 207-209
    • Grover, I.S.1    Kaur, S.2
  • 61
    • 31344479765 scopus 로고    scopus 로고
    • Chemopreventive potential of Triphala (a composite Indian drug) on benzo(a)pyrene induced forestomach tumorigenesis in murine tumor model system
    • Deep G, Dhiman M, Rao AR, Kale RK. Chemopreventive potential of Triphala (a composite Indian drug) on benzo(a)pyrene induced forestomach tumorigenesis in murine tumor model system. J Exp Clin Cancer Res 2005; 24: 555-563.
    • (2005) J Exp Clin Cancer Res , vol.24 , pp. 555-563
    • Deep, G.1    Dhiman, M.2    Rao, A.R.3    Kale, R.K.4
  • 62
    • 79960077531 scopus 로고    scopus 로고
    • The in vitro cytotoxic and apoptotic activity of Triphala - an Indian herbal drug
    • Kaur S, Michael H, Arora S, Harkonen PL, Kumar S. The in vitro cytotoxic and apoptotic activity of Triphala - an Indian herbal drug. J Ethnopharmacol 2005; 81: 327-336.
    • (2005) J Ethnopharmacol , vol.81 , pp. 327-336
    • Kaur, S.1    Michael, H.2    Arora, S.3    Harkonen, P.L.4    Kumar, S.5
  • 63
    • 0036125572 scopus 로고    scopus 로고
    • The in vitro antimutagenic activity of Triphala - an Indian herbal drug
    • Kaur S, Arora S, Kaur K, Kumar S. The in vitro antimutagenic activity of Triphala - an Indian herbal drug. Food Chem Toxicol 2002; 40: 527-534.
    • (2002) Food Chem Toxicol , vol.40 , pp. 527-534
    • Kaur, S.1    Arora, S.2    Kaur, K.3    Kumar, S.4
  • 65
    • 0033900411 scopus 로고    scopus 로고
    • In vitro inhibition of carcinogen-induced mutagenicity by Cassia occidentalis and Emblica officinalis
    • Sharma N, Trikha P, Athar M, Raisuddin S. In vitro inhibition of carcinogen-induced mutagenicity by Cassia occidentalis and Emblica officinalis. Drug Chem Toxicol 2000; 23: 477-484.
    • (2000) Drug Chem Toxicol , vol.23 , pp. 477-484
    • Sharma, N.1    Trikha, P.2    Athar, M.3    Raisuddin, S.4
  • 66
    • 0032987463 scopus 로고    scopus 로고
    • Adaptogenic properties of six Rasayana herbs used in Ayurvedic medicine
    • Rege NN, Thatte UM, Dahanukar SA. Adaptogenic properties of six Rasayana herbs used in Ayurvedic medicine. Phytother Res 1999; 13: 275-291.
    • (1999) Phytother Res , vol.13 , pp. 275-291
    • Rege, N.N.1    Thatte, U.M.2    Dahanukar, S.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.