The selection and characterization of antibodies to minichromosome maintenance proteins that highlight cervical dysplasia

Journal of Immunological Methods

Volumn 370, Issue 1-2, 2011, Pages 1-13

  Henderson, Dorian ^a   Hall, Laura ^a   Prpic, Nikki ^a   Hessling, Jan ^b   Parker, Margaret ^a   Sampson, Susan ^a   Simkins, Stephen ^a   Brough, George ^a   Dixon, Eric ^a   Lenz, Karen ^a   Knapp, Steve ^a   Murphy, Patricia ^a   Taylor, Adriann ^a   Fischer, Tim ^a   Malinowski, Douglas P ^a  

^a Becton Dickinson Diagnostic   (United States)

^b Carilion Spectrum   (United States)

Author keywords

Cervical cancer; Diagnostic epitopes; Immunocytochemistry; Minichromosome maintenance protein; Pap test; SurePath

Indexed keywords

AMINO ACID; ANTIBODY; EPITOPE; GREEN FLUORESCENT PROTEIN; MINICHROMOSOME MAINTENANCE PROTEIN; MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 3; MINICHROMOSOME MAINTENANCE PROTEIN 4; MINICHROMOSOME MAINTENANCE PROTEIN 5; MINICHROMOSOME MAINTENANCE PROTEIN 6; MINICHROMOSOME MAINTENANCE PROTEIN 7; MINICHROMOSOME MAINTENANCE PROTEIN 8; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY AFFINITY; ANTIBODY BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; EPITOPE MAPPING; HUMAN; HUMAN CELL; HUMAN TISSUE; HYBRIDOMA; IMMUNOASSAY; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE MICROARRAY; UTERINE CERVIX BIOPSY; UTERINE CERVIX CANCER; UTERINE CERVIX DYSPLASIA; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BIOPSY; BLOTTING, WESTERN; CELL CYCLE PROTEINS; DNA-BINDING PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; EPITOPES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; UTERINE CERVICAL DYSPLASIA;

EID: 79960072796     PISSN: 00221759     EISSN: 18727905     Source Type: Journal    
DOI: 10.1016/j.jim.2011.04.008     Document Type: Article

References (28)

1. Azimzadeh A., Van Regenmortel M.H. Antibody affinity measurements. J. Mol. Recognit. 1990, 3:108.
2. Badr R.E., Walts A.E., Chung F., Bose S. BD ProEx C: a sensitive and specific marker of HPV-associated squamous lesions of the cervix. Am. J. Surg. Pathol. 2008, 32:899.
3. Bosch F.X., de Sanjose S. Chapter 1: human papillomavirus and cervical cancer-burden and assessment of causality. J. Natl. Cancer Inst. Monogr. 2003, 3.
4. Brake T., Connor J.P., Petereit D.G., Lambert P.F. Comparative analysis of cervical cancer in women and in a human papillomavirus-transgenic mouse model: identification of minichromosome maintenance protein 7 as an informative biomarker for human cervical cancer. Cancer Res. 2003, 63:8173.
5. Castellsague X. Natural history and epidemiology of HPV infection and cervical cancer. Gynecol. Oncol. 2008, 110:S4.
6. Chen Y., Miller C., Mosher R., Zhao X., Deeds J., Morrissey M., Bryant B., Yang D., Meyer R., Cronin F., Gostout B.S., Smith-McCune K., Schlegel R. Identification of cervical cancer markers by cDNA and tissue microarrays. Cancer Res. 2003, 63:1927.
7. Conesa-Zamora P., Domenech-Peris A., Ortiz-Reina S., Orantes-Casado F.J., Acosta-Ortega J., Garcia-Solano J., Perez-Guillermo M. Immunohistochemical evaluation of ProEx C in human papillomavirus-induced lesions of the cervix. J. Clin. Pathol. 2009, 62:159.
8. Cox J.T., Schiffman M., Solomon D. Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 2 or 3 among women with cervical intraepithelial neoplasia grade 1 or negative colposcopy and directed biopsy. Am. J. Obstet. Gynecol. 2003, 188:1406.
9. Edwards B.K., Brown M.L., Wingo P.A., Howe H.L., Ward E., Ries L.A., Schrag D., Jamison P.M., Jemal A., Wu X.C., Friedman C., Harlan L., Warren J., Anderson R.N., Pickle L.W. Annual report to the nation on the status of cancer, 1975-2002, featuring population-based trends in cancer treatment. J. Natl. Cancer Inst. 2005, 97:1407.
10. Freeman A., Morris L.S., Mills A.D., Stoeber K., Laskey R.A., Williams G.H., Coleman N. Minichromosome maintenance proteins as biological markers of dysplasia and malignancy. Clin. Cancer Res. 1999, 5:2121.
11. Friguet B., Chaffotte A.F., Djavadi-Ohaniance L., Goldberg M.E. Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay. J. Immunol. Methods 1985, 77:305.
12. Kelly D., Kincaid E., Fansler Z., Rosenthal D.L., Clark D.P. Detection of cervical high-grade squamous intraepithelial lesions from cytologic samples using a novel immunocytochemical assay (ProEx C). Cancer 2006, 108:494.
13. Kilpatrick K.E., Wring S.A., Walker D.H., Macklin M.D., Payne J.A., Su J.L., Champion B.R., Caterson B., McIntyre G.D. Rapid development of affinity matured monoclonal antibodies using RIMMS. Hybridoma 1997, 16:381.
14. Kukimoto I., Aihara S., Yoshiike K., Kanda T. Human papillomavirus oncoprotein E6 binds to the C-terminal region of human minichromosome maintenance 7 protein. Biochem. Biophys. Res. Commun. 1998, 249:258.
15. Malinowski D.P. Molecular diagnostic assays for cervical neoplasia: emerging markers for the detection of high-grade cervical disease. Biotechniques 2005, 17. Suppl.
16. Malinowski D.P. Multiple biomarkers in molecular oncology. I. Molecular diagnostics applications in cervical cancer detection. Expert Rev. Mol. Diagn. 2007, 7:117.
17. Mukherjee G., Muralidhar B., Bafna U.D., Laskey R.A., Coleman N. MCM immunocytochemistry as a first line cervical screening test in developing countries: a prospective cohort study in a regional cancer centre in India. Br. J. Cancer 2007, 96:1107.
18. Phizicky E.M., Fields S. Protein-protein interactions: methods for detection and analysis. Microbiol. Rev. 1995, 59:94.
19. Pinto A.P., Schlecht N.F., Woo T.Y., Crum C.P., Cibas E.S. Biomarker (ProEx C, p16(INK4A), and MiB-1) distinction of high-grade squamous intraepithelial lesion from its mimics. Mod. Pathol. 2008, 21:1067.
20. Romanowski P., Madine M.A. Mechanisms restricting DNA replication to once per cell cycle: the role of Cdc6p and ORC. Trends Cell Biol. 1997, 7:9.
21. Schiffman M., Solomon D. Findings to date from the ASCUS-LSIL Triage Study (ALTS). Arch. Pathol. Lab. Med. 2003, 127:946.
22. Shi J., Liu H., Wilkerson M., Huang Y., Meschter S., Dupree W., Schuerch C., Lin F. Evaluation of p16INK4a, minichromosome maintenance protein 2, DNA topoisomerase IIalpha, ProEX C, and p16INK4a/ProEX C in cervical squamous intraepithelial lesions. Hum. Pathol. 2007, 38:1335.
23. Shroyer K.R., Homer P., Heinz D., Singh M. Validation of a novel immunocytochemical assay for topoisomerase II-alpha and minichromosome maintenance protein 2 expression in cervical cytology. Cancer 2006, 108:324.
24. Siddiqui M.T., Cohen C., Nassar A. Detecting high-grade cervical disease on ASC-H cytology: role of BD ProEx C and Digene Hybrid Capture II HPV DNA testing. Am. J. Clin. Pathol. 2008, 130:765.
25. Siddiqui M.T., Hornaman K., Cohen C., Nassar A. ProEx C immunocytochemistry and high-risk human papillomavirus DNA testing in papanicolaou tests with atypical squamous cell (ASC-US) cytology: correlation study with histologic biopsy. Arch. Pathol. Lab. Med. 2008, 132:1648.
26. Solomon D., Nayar R. The Bethesda System for Reporting Cervical Cytology 2004, Springer, New York, NY.
27. Tambouret R.H., Misdraji J., Wilbur D.C. Longitudinal clinical evaluation of a novel antibody cocktail for detection of high-grade squamous intraepithelial lesions on cervical cytology specimens. Arch. Pathol. Lab. Med. 2008, 132:918.
28. Williams G.H., Romanowski P., Morris L., Madine M., Mills A.D., Stoeber K., Marr J., Laskey R.A., Coleman N. Improved cervical smear assessment using antibodies against proteins that regulate DNA replication. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:14932.