메뉴 건너뛰기




Volumn 26, Issue 3, 2011, Pages 381-388

CK2 inhibitors enhance the radiosensitivity of human non-small cell lung cancer cells through inhibition of Stat3 activation

Author keywords

CK2; Irradiation; non small cell lung cancer; Stat3

Indexed keywords

4,5,6,7 TETRABROMO 1H BENZOTRIAZOLE; ANTINEOPLASTIC AGENT; CASEIN KINASE II; HEMATEIN; PROTEIN SERINE THREONINE KINASE INHIBITOR; RADIOSENSITIZING AGENT; RECOMBINANT EPIDERMAL GROWTH FACTOR; STAT3 PROTEIN; TETRABROMOCINNAMIC ACID; UNCLASSIFIED DRUG;

EID: 79960051228     PISSN: 10849785     EISSN: 15578852     Source Type: Journal    
DOI: 10.1089/cbr.2010.0917     Document Type: Article
Times cited : (23)

References (41)
  • 2
    • 0037269847 scopus 로고    scopus 로고
    • Protein kinase CK2: Structure, regulation and role in cellular decisions of life and death
    • Litchfield DW. Protein kinase CK2: Structure, regulation and role in cellular decisions of life and death. Biochem J 2003; 369(Pt 1):1.
    • (2003) Biochem J , vol.369 , Issue.PART 1 , pp. 1
    • Litchfield, D.W.1
  • 3
    • 0036568813 scopus 로고    scopus 로고
    • Joining the cell survival squad: An emerging role for protein kinase CK2
    • Ahmed K, Gerber DA, Cochet C. Joining the cell survival squad: An emerging role for protein kinase CK2. Trends Cell Biol 2002;12:226.
    • (2002) Trends Cell Biol , vol.12 , pp. 226
    • Ahmed, K.1    Gerber, D.A.2    Cochet, C.3
  • 4
    • 0037334895 scopus 로고    scopus 로고
    • One-thousand-and-one substrates of protein kinase CK2?
    • Meggio F, Pinna LA. One-thousand-and-one substrates of protein kinase CK2? FASEB J 2003;17:349.
    • (2003) FASEB J , vol.17 , pp. 349
    • Meggio, F.1    Pinna, L.A.2
  • 5
    • 0028122060 scopus 로고
    • Asymmetric expression of protein kinase CK2 subunits in human kidney tumors
    • Stalter G, Siemer S, Becht E, et al. Asymmetric expression of protein kinase CK2 subunits in human kidney tumors. Biochem Biophys Res Commun 1994;202:141.
    • (1994) Biochem Biophys Res Commun , vol.202 , pp. 141
    • Stalter, G.1    Siemer, S.2    Becht, E.3
  • 7
    • 0028226829 scopus 로고
    • Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung
    • Daya-Makin M, Sanghera JS, Mogentale TL, et al. Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung. Cancer Res 1994;54:2262.
    • (1994) Cancer Res , vol.54 , pp. 2262
    • Daya-Makin, M.1    Sanghera, J.S.2    Mogentale, T.L.3
  • 8
    • 0034096356 scopus 로고    scopus 로고
    • Antisense oligonucleotides against protein kinase CK2-alpha inhibit growth of squamous cell carcinoma of the head and neck in vitro
    • Faust RA, Tawfic S, Davis AT, et al. Antisense oligonucleotides against protein kinase CK2-alpha inhibit growth of squamous cell carcinoma of the head and neck in vitro. Head Neck 2000;22:341.
    • (2000) Head Neck , vol.22 , pp. 341
    • Faust, R.A.1    Tawfic, S.2    Davis, A.T.3
  • 9
    • 0028115657 scopus 로고
    • Nuclear casein kinase 2 (CK-2) activity in human normal, benign hyperplastic, and cancerous prostate
    • Yenice S, Davis AT, Goueli SA, et al. Nuclear casein kinase 2 (CK-2) activity in human normal, benign hyperplastic, and cancerous prostate. Prostate 1994;24:11.
    • (1994) Prostate , vol.24 , pp. 11
    • Yenice, S.1    Davis, A.T.2    Goueli, S.A.3
  • 10
    • 22344442950 scopus 로고    scopus 로고
    • Downregulation of CK2 induces apoptosis in cancer cells-a potential approach to cancer therapy
    • Wang G, Unger G, Ahmad KA, et al. Downregulation of CK2 induces apoptosis in cancer cells-a potential approach to cancer therapy. Mol Cell Biochem 2005;274:77.
    • (2005) Mol Cell Biochem , vol.274 , pp. 77
    • Wang, G.1    Unger, G.2    Ahmad, K.A.3
  • 11
    • 35349015771 scopus 로고    scopus 로고
    • Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level
    • Di Maira G, Brustolon F, Bertacchini J, et al. Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level. Oncogene 2007;26:6915.
    • (2007) Oncogene , vol.26 , pp. 6915
    • Di Maira, G.1    Brustolon, F.2    Bertacchini, J.3
  • 12
    • 0033553434 scopus 로고    scopus 로고
    • Inducible expression of protein kinase CK2 in mammalian cells. Evidence for functional specialization of CK2 isoforms
    • Vilk G, Saulnier RB, St Pierre R, et al. Inducible expression of protein kinase CK2 in mammalian cells. Evidence for functional specialization of CK2 isoforms. J Biol Chem 1999; 274:14406.
    • (1999) J Biol Chem , vol.274 , pp. 14406
    • Vilk, G.1    Saulnier, R.B.2    St Pierre, R.3
  • 13
    • 0035848716 scopus 로고    scopus 로고
    • A role for protein kinase CK2 in cell proliferation: Evidence using a kinaseinactive mutant of CK2 catalytic subunit alpha
    • Lebrin F, Chambaz EM, Bianchini L. A role for protein kinase CK2 in cell proliferation: Evidence using a kinaseinactive mutant of CK2 catalytic subunit alpha. Oncogene 2001;20:2010.
    • (2001) Oncogene , vol.20 , pp. 2010
    • Lebrin, F.1    Chambaz, E.M.2    Bianchini, L.3
  • 14
    • 9744244918 scopus 로고    scopus 로고
    • Optimization of protein kinase CK2 inhibitors derived from 4, 5, 6,7- tetrabromobenzimidazole
    • Pagano MA, Andrzejewska M, Ruzzene M, et al. Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7- tetrabromobenzimidazole. J Med Chem 2004;47:6239.
    • (2004) J Med Chem , vol.47 , pp. 6239
    • Pagano, M.A.1    Andrzejewska, M.2    Ruzzene, M.3
  • 15
    • 38349116517 scopus 로고    scopus 로고
    • Too much of a good thing: The role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2
    • Duncan JS, Litchfield DW. Too much of a good thing: The role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2. Biochim Biophys Acta 2008;1784:33.
    • (2008) Biochim Biophys Acta , vol.1784 , pp. 33
    • Duncan, J.S.1    Litchfield, D.W.2
  • 16
    • 34248634614 scopus 로고    scopus 로고
    • Protein kinase CK2: A newcomer in the druggable kinome
    • Pagano MA, Cesaro L, Meggio F, et al. Protein kinase CK2: A newcomer in the druggable kinome. Biochem Soc Trans 2006;34(Pt 6):1303.
    • (2006) Biochem Soc Trans , vol.34 , Issue.PART 6 , pp. 1303
    • Pagano, M.A.1    Cesaro, L.2    Meggio, F.3
  • 17
    • 33846334498 scopus 로고    scopus 로고
    • Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors
    • Pagano MA, Poletto G, Di Maira G, et al. Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors. Chembiochem 2007;8:129.
    • (2007) Chembiochem , vol.8 , pp. 129
    • Pagano, M.A.1    Poletto, G.2    Di Maira, G.3
  • 18
    • 28544438023 scopus 로고    scopus 로고
    • Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer
    • Haura EB, Zheng Z, Song L, et al. Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer. Clin Cancer Res 2005;11:8288.
    • (2005) Clin Cancer Res , vol.11 , pp. 8288
    • Haura, E.B.1    Zheng, Z.2    Song, L.3
  • 19
    • 0038505594 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor (EGFR) and downstreamactivated peptides in surgically excised non-small-cell lung cancer (NSCLC)
    • Mukohara T, Kudoh S, Yamauchi S, et al. Expression of epidermal growth factor receptor (EGFR) and downstreamactivated peptides in surgically excised non-small-cell lung cancer (NSCLC). Lung Cancer 2003;41:123.
    • (2003) Lung Cancer , vol.41 , pp. 123
    • Mukohara, T.1    Kudoh, S.2    Yamauchi, S.3
  • 20
    • 1842830790 scopus 로고    scopus 로고
    • STAT3 and MAPK in human lung cancer tissues and suppression of oncogenic growth by JAB and dominant negative STAT3
    • Seki Y, Suzuki N, Imaizumi M, et al. STAT3 and MAPK in human lung cancer tissues and suppression of oncogenic growth by JAB and dominant negative STAT3. Int J Oncol 2004;24:931.
    • (2004) Int J Oncol , vol.24 , pp. 931
    • Seki, Y.1    Suzuki, N.2    Imaizumi, M.3
  • 21
    • 33645506849 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor
    • Alvarez JV, Greulich H, Sellers WR, et al. Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor. Cancer Res 2006;66: 3162.
    • (2006) Cancer Res , vol.66 , pp. 3162
    • Alvarez, J.V.1    Greulich, H.2    Sellers, W.R.3
  • 22
    • 33746238953 scopus 로고    scopus 로고
    • Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion
    • Yeh HH, Lai WW, Chen HH, et al. Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion. Oncogene 2006;25:4300.
    • (2006) Oncogene , vol.25 , pp. 4300
    • Yeh, H.H.1    Lai, W.W.2    Chen, H.H.3
  • 23
    • 36849012237 scopus 로고    scopus 로고
    • Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas
    • Gao SP, Mark KG, Leslie K, et al. Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas. J Clin Invest 2007; 117:3846.
    • (2007) J Clin Invest , vol.117 , pp. 3846
    • Gao, S.P.1    Mark, K.G.2    Leslie, K.3
  • 24
    • 33748163052 scopus 로고    scopus 로고
    • Multiple myeloma cell survival relies on high activity of protein kinase CK2
    • Piazza FA, Ruzzene M, Gurrieri C, et al. Multiple myeloma cell survival relies on high activity of protein kinase CK2. Blood 2006;108:1698.
    • (2006) Blood , vol.108 , pp. 1698
    • Piazza, F.A.1    Ruzzene, M.2    Gurrieri, C.3
  • 26
    • 14844353135 scopus 로고    scopus 로고
    • Radiation sensitizers: A selective review of molecules targeting DNA and non-DNA targets
    • Kvols LK. Radiation sensitizers: A selective review of molecules targeting DNA and non-DNA targets. J Nucl Med 2005;46 Suppl 1:187S.
    • (2005) J Nucl Med , vol.46 , Issue.SUPPL. 1
    • Kvols, L.K.1
  • 27
    • 0028196623 scopus 로고
    • In vitro studies of taxol as a radiation sensitizer in human tumor cells
    • Liebmann J, Cook JA, Fisher J, et al. In vitro studies of taxol as a radiation sensitizer in human tumor cells. J Natl Cancer Inst 1994;86:441.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 441
    • Liebmann, J.1    Cook, J.A.2    Fisher, J.3
  • 28
    • 0034764116 scopus 로고    scopus 로고
    • Mechanism of the radiosensitization induced by vinorelbine in human non-small cell lung cancer cells
    • Fukuoka K, Arioka H, Iwamoto Y, et al. Mechanism of the radiosensitization induced by vinorelbine in human non-small cell lung cancer cells. Lung Cancer 2001; 34:451.
    • (2001) Lung Cancer , vol.34 , pp. 451
    • Fukuoka, K.1    Arioka, H.2    Iwamoto, Y.3
  • 29
    • 0030292721 scopus 로고    scopus 로고
    • Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
    • Fukada T, Hibi M, Yamanaka Y, et al. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis. Immunity 1996;5:449.
    • (1996) Immunity , vol.5 , pp. 449
    • Fukada, T.1    Hibi, M.2    Yamanaka, Y.3
  • 30
    • 33845228341 scopus 로고    scopus 로고
    • Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of Survivin following irradiation
    • Kim KW, Mutter RW, Cao C, et al. Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of Survivin following irradiation. Mol Cancer Ther 2006;5:2659.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2659
    • Kim, K.W.1    Mutter, R.W.2    Cao, C.3
  • 31
    • 55049125447 scopus 로고    scopus 로고
    • SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage
    • Sitko JC, Yeh B, Kim M, et al. SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage. Cell Signal 2008;20:2221.
    • (2008) Cell Signal , vol.20 , pp. 2221
    • Sitko, J.C.1    Yeh, B.2    Kim, M.3
  • 32
    • 33750827521 scopus 로고    scopus 로고
    • Cutting edge: Inherent and acquired resistance to radiation-induced apoptosis in B cells: A pivotal role for STAT3
    • Otero DC, Poli V, David M, et al. Cutting edge: Inherent and acquired resistance to radiation-induced apoptosis in B cells: a pivotal role for STAT3. J Immunol 2006;177:6593.
    • (2006) J Immunol , vol.177 , pp. 6593
    • Otero, D.C.1    Poli, V.2    David, M.3
  • 33
    • 20544470394 scopus 로고    scopus 로고
    • Inhibition of STAT3 activity with STAT3 antisense oligonucleotide (STAT3-ASO) enhances radiation-induced apoptosis in DU145 prostate cancer cells
    • Calvin DP, Nam S, Buettner R, et al. Inhibition of STAT3 activity with STAT3 antisense oligonucleotide (STAT3-ASO) enhances radiation-induced apoptosis in DU145 prostate cancer cells. Int J Radiat Oncol Biol Phys 2003;57:S297.
    • (2003) Int J Radiat Oncol Biol Phys , vol.57
    • Calvin, D.P.1    Nam, S.2    Buettner, R.3
  • 34
    • 0028352112 scopus 로고
    • Casein kinase II is required for transition of G0/G1, early G1, and G1/S phases of the cell cycle
    • Pepperkok R, Lorenz P, Ansorge W, et al. Casein kinase II is required for transition of G0/G1, early G1, and G1/S phases of the cell cycle. J Biol Chem 1994;269:6986.
    • (1994) J Biol Chem , vol.269 , pp. 6986
    • Pepperkok, R.1    Lorenz, P.2    Ansorge, W.3
  • 35
    • 67649289884 scopus 로고    scopus 로고
    • Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library
    • Hung MS, Xu Z, Lin YC, et al. Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library. BMC Cancer 2009;9:135.
    • (2009) BMC Cancer , vol.9 , pp. 135
    • Hung, M.S.1    Xu, Z.2    Lin, Y.C.3
  • 36
    • 4143066760 scopus 로고    scopus 로고
    • Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
    • Sordella R, Bell DW, Haber DA, et al. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 2004;305:1163.
    • (2004) Science , vol.305 , pp. 1163
    • Sordella, R.1    Bell, D.W.2    Haber, D.A.3
  • 37
    • 33644507072 scopus 로고    scopus 로고
    • Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells
    • Sato M, Vaughan MB, Girard L, et al. Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells. Cancer Res 2006;66:2116.
    • (2006) Cancer Res , vol.66 , pp. 2116
    • Sato, M.1    Vaughan, M.B.2    Girard, L.3
  • 39
    • 0035955722 scopus 로고    scopus 로고
    • UV Induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal Cl 41 cells through hydrogen peroxide
    • Huang C, Li J, Ding M, et al. UV Induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal Cl 41 cells through hydrogen peroxide. J Biol Chem 2001;276:40234.
    • (2001) J Biol Chem , vol.276 , pp. 40234
    • Huang, C.1    Li, J.2    Ding, M.3
  • 40
    • 0035872199 scopus 로고    scopus 로고
    • Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
    • Brognard J, Clark AS, Ni Y, et al. Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res 2001;61:3986.
    • (2001) Cancer Res , vol.61 , pp. 3986
    • Brognard, J.1    Clark, A.S.2    Ni, Y.3
  • 41
    • 33847361829 scopus 로고    scopus 로고
    • Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia
    • Kim JS, Eom JI, Cheong JW, et al. Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia. Clin Cancer Res 2007;13:1019.
    • (2007) Clin Cancer Res , vol.13 , pp. 1019
    • Kim, J.S.1    Eom, J.I.2    Cheong, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.