-
2
-
-
0037269847
-
Protein kinase CK2: Structure, regulation and role in cellular decisions of life and death
-
Litchfield DW. Protein kinase CK2: Structure, regulation and role in cellular decisions of life and death. Biochem J 2003; 369(Pt 1):1.
-
(2003)
Biochem J
, vol.369
, Issue.PART 1
, pp. 1
-
-
Litchfield, D.W.1
-
3
-
-
0036568813
-
Joining the cell survival squad: An emerging role for protein kinase CK2
-
Ahmed K, Gerber DA, Cochet C. Joining the cell survival squad: An emerging role for protein kinase CK2. Trends Cell Biol 2002;12:226.
-
(2002)
Trends Cell Biol
, vol.12
, pp. 226
-
-
Ahmed, K.1
Gerber, D.A.2
Cochet, C.3
-
4
-
-
0037334895
-
One-thousand-and-one substrates of protein kinase CK2?
-
Meggio F, Pinna LA. One-thousand-and-one substrates of protein kinase CK2? FASEB J 2003;17:349.
-
(2003)
FASEB J
, vol.17
, pp. 349
-
-
Meggio, F.1
Pinna, L.A.2
-
5
-
-
0028122060
-
Asymmetric expression of protein kinase CK2 subunits in human kidney tumors
-
Stalter G, Siemer S, Becht E, et al. Asymmetric expression of protein kinase CK2 subunits in human kidney tumors. Biochem Biophys Res Commun 1994;202:141.
-
(1994)
Biochem Biophys Res Commun
, vol.202
, pp. 141
-
-
Stalter, G.1
Siemer, S.2
Becht, E.3
-
7
-
-
0028226829
-
Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung
-
Daya-Makin M, Sanghera JS, Mogentale TL, et al. Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung. Cancer Res 1994;54:2262.
-
(1994)
Cancer Res
, vol.54
, pp. 2262
-
-
Daya-Makin, M.1
Sanghera, J.S.2
Mogentale, T.L.3
-
8
-
-
0034096356
-
Antisense oligonucleotides against protein kinase CK2-alpha inhibit growth of squamous cell carcinoma of the head and neck in vitro
-
Faust RA, Tawfic S, Davis AT, et al. Antisense oligonucleotides against protein kinase CK2-alpha inhibit growth of squamous cell carcinoma of the head and neck in vitro. Head Neck 2000;22:341.
-
(2000)
Head Neck
, vol.22
, pp. 341
-
-
Faust, R.A.1
Tawfic, S.2
Davis, A.T.3
-
9
-
-
0028115657
-
Nuclear casein kinase 2 (CK-2) activity in human normal, benign hyperplastic, and cancerous prostate
-
Yenice S, Davis AT, Goueli SA, et al. Nuclear casein kinase 2 (CK-2) activity in human normal, benign hyperplastic, and cancerous prostate. Prostate 1994;24:11.
-
(1994)
Prostate
, vol.24
, pp. 11
-
-
Yenice, S.1
Davis, A.T.2
Goueli, S.A.3
-
10
-
-
22344442950
-
Downregulation of CK2 induces apoptosis in cancer cells-a potential approach to cancer therapy
-
Wang G, Unger G, Ahmad KA, et al. Downregulation of CK2 induces apoptosis in cancer cells-a potential approach to cancer therapy. Mol Cell Biochem 2005;274:77.
-
(2005)
Mol Cell Biochem
, vol.274
, pp. 77
-
-
Wang, G.1
Unger, G.2
Ahmad, K.A.3
-
11
-
-
35349015771
-
Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level
-
Di Maira G, Brustolon F, Bertacchini J, et al. Pharmacological inhibition of protein kinase CK2 reverts the multidrug resistance phenotype of a CEM cell line characterized by high CK2 level. Oncogene 2007;26:6915.
-
(2007)
Oncogene
, vol.26
, pp. 6915
-
-
Di Maira, G.1
Brustolon, F.2
Bertacchini, J.3
-
12
-
-
0033553434
-
Inducible expression of protein kinase CK2 in mammalian cells. Evidence for functional specialization of CK2 isoforms
-
Vilk G, Saulnier RB, St Pierre R, et al. Inducible expression of protein kinase CK2 in mammalian cells. Evidence for functional specialization of CK2 isoforms. J Biol Chem 1999; 274:14406.
-
(1999)
J Biol Chem
, vol.274
, pp. 14406
-
-
Vilk, G.1
Saulnier, R.B.2
St Pierre, R.3
-
13
-
-
0035848716
-
A role for protein kinase CK2 in cell proliferation: Evidence using a kinaseinactive mutant of CK2 catalytic subunit alpha
-
Lebrin F, Chambaz EM, Bianchini L. A role for protein kinase CK2 in cell proliferation: Evidence using a kinaseinactive mutant of CK2 catalytic subunit alpha. Oncogene 2001;20:2010.
-
(2001)
Oncogene
, vol.20
, pp. 2010
-
-
Lebrin, F.1
Chambaz, E.M.2
Bianchini, L.3
-
14
-
-
9744244918
-
Optimization of protein kinase CK2 inhibitors derived from 4, 5, 6,7- tetrabromobenzimidazole
-
Pagano MA, Andrzejewska M, Ruzzene M, et al. Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7- tetrabromobenzimidazole. J Med Chem 2004;47:6239.
-
(2004)
J Med Chem
, vol.47
, pp. 6239
-
-
Pagano, M.A.1
Andrzejewska, M.2
Ruzzene, M.3
-
15
-
-
38349116517
-
Too much of a good thing: The role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2
-
Duncan JS, Litchfield DW. Too much of a good thing: The role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2. Biochim Biophys Acta 2008;1784:33.
-
(2008)
Biochim Biophys Acta
, vol.1784
, pp. 33
-
-
Duncan, J.S.1
Litchfield, D.W.2
-
16
-
-
34248634614
-
Protein kinase CK2: A newcomer in the druggable kinome
-
Pagano MA, Cesaro L, Meggio F, et al. Protein kinase CK2: A newcomer in the druggable kinome. Biochem Soc Trans 2006;34(Pt 6):1303.
-
(2006)
Biochem Soc Trans
, vol.34
, Issue.PART 6
, pp. 1303
-
-
Pagano, M.A.1
Cesaro, L.2
Meggio, F.3
-
17
-
-
33846334498
-
Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors
-
Pagano MA, Poletto G, Di Maira G, et al. Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors. Chembiochem 2007;8:129.
-
(2007)
Chembiochem
, vol.8
, pp. 129
-
-
Pagano, M.A.1
Poletto, G.2
Di Maira, G.3
-
18
-
-
28544438023
-
Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer
-
Haura EB, Zheng Z, Song L, et al. Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer. Clin Cancer Res 2005;11:8288.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8288
-
-
Haura, E.B.1
Zheng, Z.2
Song, L.3
-
19
-
-
0038505594
-
Expression of epidermal growth factor receptor (EGFR) and downstreamactivated peptides in surgically excised non-small-cell lung cancer (NSCLC)
-
Mukohara T, Kudoh S, Yamauchi S, et al. Expression of epidermal growth factor receptor (EGFR) and downstreamactivated peptides in surgically excised non-small-cell lung cancer (NSCLC). Lung Cancer 2003;41:123.
-
(2003)
Lung Cancer
, vol.41
, pp. 123
-
-
Mukohara, T.1
Kudoh, S.2
Yamauchi, S.3
-
20
-
-
1842830790
-
STAT3 and MAPK in human lung cancer tissues and suppression of oncogenic growth by JAB and dominant negative STAT3
-
Seki Y, Suzuki N, Imaizumi M, et al. STAT3 and MAPK in human lung cancer tissues and suppression of oncogenic growth by JAB and dominant negative STAT3. Int J Oncol 2004;24:931.
-
(2004)
Int J Oncol
, vol.24
, pp. 931
-
-
Seki, Y.1
Suzuki, N.2
Imaizumi, M.3
-
21
-
-
33645506849
-
Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor
-
Alvarez JV, Greulich H, Sellers WR, et al. Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor. Cancer Res 2006;66: 3162.
-
(2006)
Cancer Res
, vol.66
, pp. 3162
-
-
Alvarez, J.V.1
Greulich, H.2
Sellers, W.R.3
-
22
-
-
33746238953
-
Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion
-
Yeh HH, Lai WW, Chen HH, et al. Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion. Oncogene 2006;25:4300.
-
(2006)
Oncogene
, vol.25
, pp. 4300
-
-
Yeh, H.H.1
Lai, W.W.2
Chen, H.H.3
-
23
-
-
36849012237
-
Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas
-
Gao SP, Mark KG, Leslie K, et al. Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas. J Clin Invest 2007; 117:3846.
-
(2007)
J Clin Invest
, vol.117
, pp. 3846
-
-
Gao, S.P.1
Mark, K.G.2
Leslie, K.3
-
24
-
-
33748163052
-
Multiple myeloma cell survival relies on high activity of protein kinase CK2
-
Piazza FA, Ruzzene M, Gurrieri C, et al. Multiple myeloma cell survival relies on high activity of protein kinase CK2. Blood 2006;108:1698.
-
(2006)
Blood
, vol.108
, pp. 1698
-
-
Piazza, F.A.1
Ruzzene, M.2
Gurrieri, C.3
-
26
-
-
14844353135
-
Radiation sensitizers: A selective review of molecules targeting DNA and non-DNA targets
-
Kvols LK. Radiation sensitizers: A selective review of molecules targeting DNA and non-DNA targets. J Nucl Med 2005;46 Suppl 1:187S.
-
(2005)
J Nucl Med
, vol.46
, Issue.SUPPL. 1
-
-
Kvols, L.K.1
-
27
-
-
0028196623
-
In vitro studies of taxol as a radiation sensitizer in human tumor cells
-
Liebmann J, Cook JA, Fisher J, et al. In vitro studies of taxol as a radiation sensitizer in human tumor cells. J Natl Cancer Inst 1994;86:441.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 441
-
-
Liebmann, J.1
Cook, J.A.2
Fisher, J.3
-
28
-
-
0034764116
-
Mechanism of the radiosensitization induced by vinorelbine in human non-small cell lung cancer cells
-
Fukuoka K, Arioka H, Iwamoto Y, et al. Mechanism of the radiosensitization induced by vinorelbine in human non-small cell lung cancer cells. Lung Cancer 2001; 34:451.
-
(2001)
Lung Cancer
, vol.34
, pp. 451
-
-
Fukuoka, K.1
Arioka, H.2
Iwamoto, Y.3
-
29
-
-
0030292721
-
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
-
Fukada T, Hibi M, Yamanaka Y, et al. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis. Immunity 1996;5:449.
-
(1996)
Immunity
, vol.5
, pp. 449
-
-
Fukada, T.1
Hibi, M.2
Yamanaka, Y.3
-
30
-
-
33845228341
-
Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of Survivin following irradiation
-
Kim KW, Mutter RW, Cao C, et al. Inhibition of signal transducer and activator of transcription 3 activity results in down-regulation of Survivin following irradiation. Mol Cancer Ther 2006;5:2659.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2659
-
-
Kim, K.W.1
Mutter, R.W.2
Cao, C.3
-
31
-
-
55049125447
-
SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage
-
Sitko JC, Yeh B, Kim M, et al. SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage. Cell Signal 2008;20:2221.
-
(2008)
Cell Signal
, vol.20
, pp. 2221
-
-
Sitko, J.C.1
Yeh, B.2
Kim, M.3
-
32
-
-
33750827521
-
Cutting edge: Inherent and acquired resistance to radiation-induced apoptosis in B cells: A pivotal role for STAT3
-
Otero DC, Poli V, David M, et al. Cutting edge: Inherent and acquired resistance to radiation-induced apoptosis in B cells: a pivotal role for STAT3. J Immunol 2006;177:6593.
-
(2006)
J Immunol
, vol.177
, pp. 6593
-
-
Otero, D.C.1
Poli, V.2
David, M.3
-
33
-
-
20544470394
-
Inhibition of STAT3 activity with STAT3 antisense oligonucleotide (STAT3-ASO) enhances radiation-induced apoptosis in DU145 prostate cancer cells
-
Calvin DP, Nam S, Buettner R, et al. Inhibition of STAT3 activity with STAT3 antisense oligonucleotide (STAT3-ASO) enhances radiation-induced apoptosis in DU145 prostate cancer cells. Int J Radiat Oncol Biol Phys 2003;57:S297.
-
(2003)
Int J Radiat Oncol Biol Phys
, vol.57
-
-
Calvin, D.P.1
Nam, S.2
Buettner, R.3
-
34
-
-
0028352112
-
Casein kinase II is required for transition of G0/G1, early G1, and G1/S phases of the cell cycle
-
Pepperkok R, Lorenz P, Ansorge W, et al. Casein kinase II is required for transition of G0/G1, early G1, and G1/S phases of the cell cycle. J Biol Chem 1994;269:6986.
-
(1994)
J Biol Chem
, vol.269
, pp. 6986
-
-
Pepperkok, R.1
Lorenz, P.2
Ansorge, W.3
-
35
-
-
67649289884
-
Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library
-
Hung MS, Xu Z, Lin YC, et al. Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library. BMC Cancer 2009;9:135.
-
(2009)
BMC Cancer
, vol.9
, pp. 135
-
-
Hung, M.S.1
Xu, Z.2
Lin, Y.C.3
-
36
-
-
4143066760
-
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
-
Sordella R, Bell DW, Haber DA, et al. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 2004;305:1163.
-
(2004)
Science
, vol.305
, pp. 1163
-
-
Sordella, R.1
Bell, D.W.2
Haber, D.A.3
-
37
-
-
33644507072
-
Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells
-
Sato M, Vaughan MB, Girard L, et al. Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells. Cancer Res 2006;66:2116.
-
(2006)
Cancer Res
, vol.66
, pp. 2116
-
-
Sato, M.1
Vaughan, M.B.2
Girard, L.3
-
39
-
-
0035955722
-
UV Induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal Cl 41 cells through hydrogen peroxide
-
Huang C, Li J, Ding M, et al. UV Induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal Cl 41 cells through hydrogen peroxide. J Biol Chem 2001;276:40234.
-
(2001)
J Biol Chem
, vol.276
, pp. 40234
-
-
Huang, C.1
Li, J.2
Ding, M.3
-
40
-
-
0035872199
-
Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation
-
Brognard J, Clark AS, Ni Y, et al. Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res 2001;61:3986.
-
(2001)
Cancer Res
, vol.61
, pp. 3986
-
-
Brognard, J.1
Clark, A.S.2
Ni, Y.3
-
41
-
-
33847361829
-
Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia
-
Kim JS, Eom JI, Cheong JW, et al. Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia. Clin Cancer Res 2007;13:1019.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1019
-
-
Kim, J.S.1
Eom, J.I.2
Cheong, J.W.3
|