The Shaggy Inc Cap medicinal mushroom, Coprinus comatus (O.F.Mull.: Fr.) Pers. (Agaricomycetideae) substances interfere with H2o2 induction of the NF-κB pathway through inhibition of IκBα phosphorylation in MCF7 breast cancer cells

International Journal of Medicinal Mushrooms

Volumn 13, Issue 1, 2011, Pages 19-25

  Asatiani, Mikheil D ^a,b   Wasser, Solomon P ^a,c   Nevo, Eviatar ^a   Ruimi, Nili ^d   Mahajna, Jamal ^d   Reznick, Abraham Z ^b  

^a UNIVERSITY OF HAIFA   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c M G KHOLODNY INSTITUTE OF BOTANY   (Ukraine)

^d MIGAL GALILEE TECHNOLOGY CENTER   (Israel)

Author keywords

Coprinus comatus substances; I B phosphorylation; IKK complex; Medicinal mushrooms; NF B activation pathway

Indexed keywords

ACETIC ACID ETHYL ESTER; COPRINUS COMATUS EXTRACT; CURCUMIN; FUNGAL EXTRACT; HYDROGEN PEROXIDE; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; COPRINUS COMATUS; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; IC 50; INHIBITION KINETICS; MEDICINAL SPECIES; MUSHROOM; PROTEIN PHOSPHORYLATION;

ACETATES; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; COMPLEX MIXTURES; COPRINUS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; HYDROGEN PEROXIDE; I-KAPPA B KINASE; I-KAPPA B PROTEINS; INHIBITORY CONCENTRATION 50; NF-KAPPA B; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TIME FACTORS;

BASIDIOMYCOTA; COPRINUS COMATUS;

EID: 79960038867     PISSN: 15219437     EISSN: 19404344     Source Type: Journal    
DOI: 10.1615/IntJMedMushr.v13.i1.30     Document Type: Article

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