Growth factor release in extra- and intramedullary osteosynthesis following tibial fracture

Injury

Volumn 42, Issue 8, 2011, Pages 772-777

  Sarahrudi, K ^a   Thomas, A ^a   Heinz, T ^a   Krumbock A ^a   Vecsei V ^a   Aharinejad, S ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Intramedullary fixation; M CSF; Plate fixation; TGF 1; Tibia fracture; VEGF

Indexed keywords

COLONY STIMULATING FACTOR 1; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN;

ADULT; AGED; ARTICLE; CLINICAL EXAMINATION; CONTROLLED STUDY; FEMALE; FRACTURE HEALING; HUMAN; INTERMETHOD COMPARISON; INTRAMEDULLARY NAILING; MAJOR CLINICAL STUDY; MALE; OPEN REDUCTION; OSTEOSYNTHESIS; PLATE FIXATION; PRIORITY JOURNAL; RADIODIAGNOSIS; TIBIA FRACTURE;

ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; BONE PLATES; FEMALE; FRACTURE FIXATION, INTERNAL; FRACTURE FIXATION, INTRAMEDULLARY; FRACTURE HEALING; HUMANS; MACROPHAGE COLONY-STIMULATING FACTOR; MALE; MIDDLE AGED; TIBIAL FRACTURES; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA1; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A; YOUNG ADULT;

EID: 79960026105     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/j.injury.2010.11.021     Document Type: Article

References (53)

1. P. Augat, J. Merk, and S. Wolf Mechanical stimulation by external application of cyclic tensile strains does not effectively enhance bone healing J Orthop Trauma 15 1 2001 54 60 (Pubitemid 33602166)
2. A. Bailon-Plaza, and M.C. van der Meulen Beneficial effects of moderate, early loading and adverse effects of delayed or excessive loading on bone healing J Biomech 36 2003 1069 1077 (Pubitemid 36794102)
3. G.L. Barnes, L.C. Kostenuik, L.C. Gerstenfeld, and T.A. Einhorn Growth factor regulation of fracture repair J Bone Miner Res 14 1999 1805 1815 (Pubitemid 29521774)
4. D.C. Bauer, C. Rosen, J. Cauley, and S.R. Cummings Low serum IGF-1 but not IGFBP-3 predicts hip and spine fracture: the study of osteoporotic fracture Bone 23 1998 561
5. L. Beck, E. Amento, Y. Xu, L. Deguzman, W. Lee, T. Nguyen, and N. Gillet TGF-beta1 induces bone closure of skull defects - temporal dynamics of bone formation in defects exposed to rhTGF-beta1 J Bone Miner Res 8 1993 753 761 (Pubitemid 23157800)
6. N.T. Bennett, and G.S. Schultz Growth factors and wound healing. Part II. Role in normal and chronic wound healing Am J Surg 166 1993 74 81 (Pubitemid 23281429)
7. L.B. Bone, and K.D. Johnson Treatment of tibial fractures by reaming and intramedullary nailing J Bone Joint Surg Am 68 1986 877 887 (Pubitemid 16074363)
8. I. Blumenfeld, S. Srouji, Y. Lanir, D. Laufer, and E. Livne Enhancement of bone defect healing in old rat by TGF-beta and IGF-1 Exp Gerontol 37 2002 553 565 (Pubitemid 34119160)
9. M.P. Bostorm, J.M. Lane, and W.S. Berberia Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing J Orthop Res 13 1995 357 367
10. M. Brookes, A.C. Elkin, R.G. Harrison, and C.B. Heald A new concept of capillary circulation in bone cortex Lancet 1 1961 1078 1081
11. M.W. Chapman The effect of reamed and nonreamed intramedullary nailing on fracture healing Clin Orthop 355 Suppl. 1998 S230 S238
12. E.Y. Chao, N. Inoue, and J.J. Elias Enhancement of fracture healing by mechanical and surgical intervention Clin Orthop 355 Suppl. 1998 S163 S178
13. L. Claes, K. Eckert-Hubner, and P. Augat The effect of mechanical stability on local vascularization and tissue differentiation in callus healing J Orthop Res 20 2002 1099 1105
14. L. Claes, S. Wolf, and P. Augat Mechanical modification of callus healing Chirurgia 71 9 2000 989 994
15. L.E. Claes, and C.A. Heigele Magnitudes of local stress and strain along bony surfaces predict the course and type of fracture healing J Biomech 32 1999 255 266 (Pubitemid 29125449)
16. M.M. Deckers, R.L. van Bezooijen, and G. van der Horst Bone morphogenetic proteins stimulate angiogenesis through osteoblast-derived vascular endothelial growth factor A Endocrinology 143 2002 1545 1553 (Pubitemid 34274386)
17. H. Eckardt, M. Ding, M. Lind, E.S. Hansen, K.S. Christensen, and I. Hvid Recombinant human vascular endothelial growth factor enhances bone healing in an experimental nonunion model J Bone Joint Surg Br 87-B 2005 1434 1438 (Pubitemid 41511813)
18. J.P. Frolke, F.C. Bakker, P. Patka, and H.J. Haarman Reaming debris in osteotomized sheep tibiae J Trauma 50 2001 65 69
19. J.P. Frolke, J.K. Nulend, C.M. Semeins, F.C. Bakker, P. Patka, and H.J. Haarman Viable osteoblastic potential of cortical reamings from intramedullary nailing J Orthop Res 22 2004 1271 1275 (Pubitemid 39317918)
20. D. Gazit, M. Karmish, L. Holzman, and I. Bab Regenerating marrow induces systemic increase in osteo- and chondrogenesis Endocrinology 83-A 1990 151 158
21. P.V. Giannoudis, A.J. Furlong, D.A. MacDonald, and R.M. Smith Reamed against unreamed nailing of the femoral diaphysis: a retrospective study of healing time Injury 28 1997 15 18 (Pubitemid 27242872)
22. P.V. Giannoudis, I. Pountos, J. Morley, S. Perry, H.I. Tarkin, and H.C. Pape Growth factor release following femoral nailing Bone 42 2008 751 757
23. A.E. Goodship, J.L. Cunningham, and J. Kenwright Strain rate and timing of stimulation in mechanical modulation of fracture healing Clin Orthop 355 Suppl. 1998 S105 S115
24. M. Jagodzinski, and C. Krettek Effect of mechanical stability on fracture healing - an update Injury 38 Suppl. 1 2007 S3 S10
25. C.P. Kiristy, A.B. Lynch, and S.E. Lynch Role of growth factors in cutaneous wound healing: a review Crit Rev Oral Biol Med 4 1993 729 760
26. P. Klein, H. Schell, and F. Streitparth The initial phase of fracture healing is specifically sensitive to mechanical conditions J Orthop Res 21 2003 662 669 (Pubitemid 36758210)
27. J. Kleinheinz, H.P. Wiesmann, U. Stratmann, and U. Joos Evaluating angiogenesis and osteogenesis modified by vascular endothelial growth factor (VEGF) Mund Kiefer Gesichtschir 6 2002 175 182
28. Y.Y. Kong, H. Yoshida, and I. Sarosi OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis Nature 397 6717 (January 28) 1999 315 323
29. A.X. Le, T. Miclau, and D. Hu Molecular aspects of healing in stabilized and non-stabilized fractures J Orthop Res 19 2001 78 84 (Pubitemid 32288639)
30. M. Lind, B. Schumaker, K. Sobale, J. Keller, F. Melsen, and C. Bunger Transforming growth factor beta-1 enhances fracture healing in rabbit tibiae Acta Orthop Scand 64 1993 553 556 (Pubitemid 23329864)
31. M.H. Malik, P. Harwood, P. Diggle, and S.A. Khan Factors affecting rates of infection and nonunion in intramedullary nailing J Bone Joint Surg Br 86 2004 556 560 (Pubitemid 38660061)
32. H. Mark, A. Nilsson, and U. Nannmark Effects of fracture fixation stability on ossification in healing fractures Clin Orthop 419 2004 245 250 (Pubitemid 38269701)
33. S.C. Marks The structural basis for bone cell biology Acta Med Dent Helv 2 1997 141 157 (Pubitemid 127080275)
34. P. Martin, J. Hopkinson-Woolley, and J. McCluskey Growth factors and cutaneous wound repair Prog Growth Factor Res 4 1992 25 44
35. T. Miclau, C. Lu, and Z. Thompson The effect of varying time to stabilization on fracture repair Trans Orthop Res Soc 29 2004 0483
36. C.A. Mueller, P.H. Morakis, P. Strohm, and U. Pfister Intramedullary nailing of the tibia: current status of primary undreamed intramedullary nailing. Part 2. Results for open fractures Injury 3 Suppl. 1999 44 54
37. C.A. Mueller, P. Strohm, P.H. Morakis, and U. Pfister Intramedullary nailing of the tibia: current status of primary unreamed nailing. Part 1. Results of closed fractures Injury 3 Suppl. 1999 37 43
38. M.E. Muller Classification and international AO-documentation of femur fractures Unfallheilkunde 83 1980 251 259 (Pubitemid 10100480)
39. P.A. Reynders, and P.L.O. Broos Healing of closed femoral shaft fractures treated with the AO unreamed femoral nail. A comparative study with the AO reamed femoral nail Injury 31 2000 367 371 (Pubitemid 30206986)
40. F.W. Rhinelander Tibial blood supply in relation to fracture healing Clin Orthop Relat Res 105 1974 34 81
41. K. Sarahrudi, M. Mousavi, A. Thomas, S. Eipeldauer, V. Vécsei, P. Pietschmann, and S. Aharinejad Elevated levels of macrophage colony-stimulating factor (M-CSF) in human fracture healing J Orthop Res 28 2010 671 676
42. K. Sarahrudi, A. Thomas, T. Braunsteiner, H. Wolf, V. Vécsei, and S. Aharinejad VEGF serum concentrations in patients with long bone fractures; a comparison between impaired and normal fracture healing J Orthop Res 27 2009 1293 1297
43. E.R. Stanley, K.L. Berg, D.B. Einstein, P.S. Lee, and Y.G. Yeung The biology and action of colony-stimulating facor-1 Stem Cells Suppl. 1 1994 15 24
44. J. Street, M. Bao, and L. deGuzman Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover Proc Natl Acad Sci U S A 99 2002 9656 9661 (Pubitemid 34831103)
45. P. Tornetta, and D. Tiburzi Reamed versus nonreamed anterograde femoral nailing J Orthop Trauma 14 2000 15 19
46. A. Trias, and A. Fery Cortical circulation of long bones J Bone Joint Surg Am 61-A 1979 1052 1059 (Pubitemid 10250148)
47. M. Wagner, A. Frenk, and R. Frigg New concepts for bone fracture treatment and the locking compression plate Surg Technol Int 12 2004 271 277
48. A.L. Wallace, E.R. Draper, and R.K. Strachan The vascular response to fracture micromovement Clin Orthop 301 1994 281 290 (Pubitemid 24119287)
49. E.C. Weir, G.Q. Yao, Chen, Yan, Insogna, and L. Karl Colony-stimulating factors and bone E. Canalis, Skeletal growth factors 2000 Lippincott Williams & Wilkins Philadelphia 385 409
50. S. Wenisch, K. Trinkaus, A. Hild, D. Hose, K. Herde, C. Heiss, O. Kilian, V. Alt, and R. Schnettler Human reaming debris: a source of multipotent stem cells Bone 36 2005 74 83 (Pubitemid 40128277)
51. B. Wildemann, G. Schmidmaier, S. Ordel, R. Stange, N.P. Haas, and M. Raschke Cell proliferation and differentiation during fracture healing are influenced by locally applied IGF-I and TGF-beta1: comparison of two proliferation markers, PCNA and BrdU J Biomed Mater Res B: Appl Biomater 65 2003 150 156 (Pubitemid 37521387)
52. Y. Yoshimura, S. Nomura, S. Kawasaki, T. Tsutsumimoto, T. Shimizu, and K. Takaoka Colocalization of noggin and bone morphogenetic protein-4 during fracture healing J Bone Miner Res 16 2001 876 884 (Pubitemid 32332297)
53. G. Zimmermann, P. Henle, M. Küsswetter, A. Moghaddam, A. Wentzensen, W. Richter, and S. Weiss TGF-β1 as marker of delayed fracture healing Bone 36 2005 779 785 (Pubitemid 40616012)