Association of recurrent cerebral infarction with adenosine diphosphate- and collagen-induced platelet aggregation in patients treated with ticlopidine and/or aspirin

Journal of Stroke and Cerebrovascular Diseases

Volumn 20, Issue 4, 2011, Pages 319-323

  Abumiya, Takeo ^a   Houkin, Kiyohiro ^b  

^a Hokkaido Neurosurgical Memorial Hospital   (Japan)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Antiplatelet therapy; ischemic stroke; secondary prevention

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; COLLAGEN; TICLOPIDINE;

ADULT; AGED; ARTICLE; BRAIN INFARCTION; CARDIOVASCULAR DISEASE; COMPARATIVE STUDY; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; INCIDENCE; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE; OBESITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECURRENCE RISK; RECURRENT DISEASE; RISK FACTOR; SMOKING; THROMBOCYTE AGGREGATION;

ADENOSINE DIPHOSPHATE; AGED; ASPIRIN; CEREBRAL INFARCTION; CHI-SQUARE DISTRIBUTION; COLLAGEN; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; JAPAN; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; PILOT PROJECTS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET FUNCTION TESTS; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RECURRENCE; SECONDARY PREVENTION; TICLOPIDINE; TIME FACTORS; TREATMENT OUTCOME;

EID: 79960004400     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2010.01.013     Document Type: Article

References (26)

1. Antithrombotic Trialists' Collaboration Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients BMJ 324 2002 71 86
2. G. Krasopoulos, S.J. Brister, and W.S. Beattie Aspirin "resistance" and risk of cardiovascular morbidity: Systematic review and meta-analysis BMJ 336 2008 195 198 (Pubitemid 351212675)
3. A.Y. Gasparyan, T. Watson, and G.Y. Lip The role of aspirin in cardiovascular prevention: Implications of aspirin resistance J Am Coll Cardiol 51 2008 1829 1843 (Pubitemid 351615246)
4. P.J. Mason, A.K. Jacobs, and J.E. Freedman Aspirin resistance and atherothrombotic disease J Am Coll Cardiol 46 2005 986 993 (Pubitemid 41316504)
5. Y. Nagakawa, Y. Akedo, and H. Orimo Effect of the combination of antiplatelet agents in man: Combination of aspirin, trapidil, ticlopidine and dipyridamole Thromb Res 60 1990 469 475
6. R. Gan, R.A. Teleg, and L. Florento Effect of increasing doses of aspirin on platelet aggregation among stroke patients Cerebrovasc Dis 14 2002 252 255 (Pubitemid 36151426)
7. M. Cattaneo, B. Akkawat, and A. Lecchi Ticlopidine selectively inhibits human platelet responses to adenosine diphosphate Thromb Haemost 66 1991 694 699
8. O. Cuyun-Lira, M. Kaneko, and T. Takafuta Inhibitory effects of ticlopidine on platelet function as assessed by three different methods Eur J Pharm Sci 30 2007 21 25 (Pubitemid 44908923)
9. K. Moshfegh, M. Redondo, and F. Julmy Antiplatelet effects of clopidogrel compared with aspirin after myocardial infarction: Enhanced inhibitory effects of combination therapy J Am Coll Cardiol 36 2000 699 705
10. P.A. Gurbel, K.P. Bliden, and W. Samara Clopidogrel effect on platelet reactivity in patients with stent thrombosis: Results of the CREST Study J Am Coll Cardiol 46 2005 1827 1832 (Pubitemid 41579803)
11. P.A. Gurbel, K.P. Bliden, and K. Guyer Platelet reactivity in patients and recurrent events post-stenting: Results of the PREPARE POST-STENTING Study J Am Coll Cardiol 46 2005 1820 1826 (Pubitemid 41579802)
12. K.P. Bliden, J. DiChiara, and U.S. Tantry Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention: Is the current antiplatelet therapy adequate? J Am Coll Cardiol 49 2007 657 666 (Pubitemid 46205039)
13. S. Matetzky, B. Shenkman, and V. Guetta Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction Circulation 109 2004 3171 3175
14. T. Geisler, H. Langer, and M. Wydymus Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation Eur Heart J 27 2006 2420 2425 (Pubitemid 44522148)
15. T. Ohmori, Y. Yatomi, and T. Nonaka Aspirin resistance detected with aggregometry cannot be explained by cyclooxygenase activity: Involvement of other signaling pathway(s) in cardiovascular events of aspirin-treated patients J Thromb Haemost 4 2006 1271 1278
16. N. Kotzailias, K. Elwischger, and T. Sycha Clopidogrel-induced platelet inhibition cannot be detected by the platelet function analyzer-100 system in stroke patients J Stroke Cerebrovasc Dis 16 2007 199 202 (Pubitemid 47369190)
17. K. Grundmann, K. Jaschonek, and B. Kleine Aspirin non-responder status in patients with recurrent cerebral ischemic attacks J Neurol 250 2003 63 66 (Pubitemid 36206686)
18. F.M. Gengo, M. Rainka, and M. Robson Prevalence of platelet nonresponsiveness to aspirin in patients treated for secondary stroke prophylaxis and in patients with recurrent ischemic events J Clin Pharmacol 48 2008 335 343 (Pubitemid 351257777)
19. The Caerphilly and Speedwell Collaborative Group Caerphilly and Speedwell collaborative heart disease studies J Epidemiol Community Health 38 1984 259 262
20. P.C. Elwood, A. Beswick, and J. Pickering Platelet tests in the prediction of myocardial infarction and ischaemic stroke: Evidence from the Caerphilly Prospective Study Br J Haematol 113 2001 514 520 (Pubitemid 32523163)
21. D.S. Sharp, Y. Ben-Shlomo, and A.D. Beswick Platelet aggregation in whole blood is a paradoxical predictor of ischaemic stroke: Caerphilly Prospective Study revisited Platelets 16 2005 320 328 (Pubitemid 41491700)
22. F. von Lewinski, J. Riggert, and W. Paulus Towards a rationale of platelet aggregation monitoring in stroke prophylaxis? J Stroke Cerebrovasc Dis 18 2009 111 115
23. A.J. Grau, S. Reiners, and C. Lichy Platelet function under aspirin, clopidogrel, and both after ischemic stroke: A case-crossover study Stroke 34 2003 849 854 (Pubitemid 36402949)
24. P. Harrison, H. Segal, and K. Blasbery Screening for aspirin responsiveness after transient ischemic attack and stroke: Comparison of 2 point-of-care platelet function tests with optical aggregometry Stroke 36 2005 1001 1005 (Pubitemid 40629292)
25. N. Kotzailias, K. Elwischger, and T. Sycha Clopidogrel-induced platelet inhibition cannot be detected by the platelet function analyzer-100 system in stroke patients J Stroke Cerebrovasc Dis 16 2007 199 202 (Pubitemid 47369190)
26. V.L. Serebruany, A.I. Malinin, and W. Ziai Effects of clopidogrel and aspirin in combination versus aspirin alone on platelet activation and major receptor expression in patients after recent ischemic stroke: For the Plavix Use for Treatment of Stroke (PLUTO-Stroke) trial Stroke 36 2005 2289 2292 (Pubitemid 41429264)