메뉴 건너뛰기




Volumn 108, Issue 24, 2011, Pages 9887-9892

Drosophila homeodomain-interacting protein kinase inhibits the Skp1-Cul1-F-box E3 ligase complex to dually promote Wingless and Hedgehog signaling

Author keywords

Beta TrCP; Wnt

Indexed keywords

ARMADILLO DOMAIN PROTEIN; HOMEODOMAIN INTERACTING PROTEIN KINASE; HOMEODOMAIN PROTEIN; SKP1 CUL1 F BOX E3 LIGASE COMPLEX; SONIC HEDGEHOG PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; WNT1 PROTEIN;

EID: 79959993178     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1017548108     Document Type: Article
Times cited : (43)

References (28)
  • 1
    • 0031456158 scopus 로고    scopus 로고
    • Wnt signaling: A common theme in animal development
    • Cadigan KM, Nusse R (1997) Wnt signaling: A common theme in animal development. Genes Dev 11:3286-3305. (Pubitemid 28023954)
    • (1997) Genes and Development , vol.11 , Issue.24 , pp. 3286-3305
    • Cadigan, K.M.1    Nusse, R.2
  • 2
    • 77149174855 scopus 로고    scopus 로고
    • Wnt signaling from development to disease: Insights from model systems
    • Cadigan KM, Peifer M (2009) Wnt signaling from development to disease: Insights from model systems. Cold Spring Harb Perspect Biol 1:a002881.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Cadigan, K.M.1    Peifer, M.2
  • 3
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H (2006) Wnt/beta-catenin signaling in development and disease. Cell 127:469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 4
    • 18744400798 scopus 로고    scopus 로고
    • Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
    • DOI 10.1038/nsmb912
    • Daniels DL, Weis WI (2005) Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation. Nat Struct Mol Biol 12:364-371. (Pubitemid 43093092)
    • (2005) Nature Structural and Molecular Biology , vol.12 , Issue.4 , pp. 364-371
    • Daniels, D.L.1    Weis, W.I.2
  • 5
    • 73949093736 scopus 로고    scopus 로고
    • Regulation of Wnt/beta-catenin signaling by protein kinases
    • Verheyen EM, Gottardi CJ (2010) Regulation of Wnt/beta-catenin signaling by protein kinases. Dev Dyn 239:34-44.
    • (2010) Dev Dyn , vol.239 , pp. 34-44
    • Verheyen, E.M.1    Gottardi, C.J.2
  • 6
    • 33845351956 scopus 로고    scopus 로고
    • beta-Catenin destruction complex: Insights and questions from a structural perspective
    • DOI 10.1038/sj.onc.1210055, PII 1210055
    • Kimelman D, Xu W (2006) beta-catenin destruction complex: Insights and questions from a structural perspective. Oncogene 25:7482-7491. (Pubitemid 44885747)
    • (2006) Oncogene , vol.25 , Issue.57 , pp. 7482-7491
    • Kimelman, D.1    Xu, W.2
  • 7
    • 0029683606 scopus 로고    scopus 로고
    • The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
    • Yost C, et al. (1996) The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3. Genes Dev 10:1443-1454. (Pubitemid 26260702)
    • (1996) Genes and Development , vol.10 , Issue.12 , pp. 1443-1454
    • Yost, C.1    Torres, M.2    Miller, J.R.3    Huang, E.4    Kimelman, D.5    Moon, R.T.6
  • 8
    • 0037155691 scopus 로고    scopus 로고
    • Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
    • DOI 10.1016/S0092-8674(02)00685-2
    • Liu C, et al. (2002) Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 108:837-847. (Pubitemid 34327534)
    • (2002) Cell , vol.108 , Issue.6 , pp. 837-847
    • Liu, C.1    Li, Y.2    Semenov, M.3    Han, C.4    Baeg, G.-H.5    Tan, Y.6    Zhang, Z.7    Lin, X.8    He, X.9
  • 9
    • 0344442773 scopus 로고    scopus 로고
    • Crystal structure of a beta-catenin/Axin complex suggests a mechanism for the beta-catenin destruction complex
    • DOI 10.1101/gad.1142603
    • Xing Y, Clements WK, Kimelman D, Xu W (2003) Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex. Genes Dev 17:2753-2764. (Pubitemid 37463285)
    • (2003) Genes and Development , vol.17 , Issue.22 , pp. 2753-2764
    • Xing, Y.1    Clements, W.K.2    Kimelman, D.3    Xu, W.4
  • 10
    • 56849086074 scopus 로고    scopus 로고
    • APC is essential for targeting phosphorylated beta-catenin to the SCFbeta-TrCP ubiquitin ligase
    • Su Y, et al. (2008) APC is essential for targeting phosphorylated beta-catenin to the SCFbeta-TrCP ubiquitin ligase. Mol Cell 32:652-661.
    • (2008) Mol Cell , vol.32 , pp. 652-661
    • Su, Y.1
  • 11
    • 0034791090 scopus 로고    scopus 로고
    • Ubiquitin enters the new millennium
    • Pickart CM (2001) Ubiquitin enters the new millennium. Mol Cell 8:499-504.
    • (2001) Mol Cell , vol.8 , pp. 499-504
    • Pickart, C.M.1
  • 12
    • 77749341438 scopus 로고    scopus 로고
    • Ubiquitin ligase complexes: From substrate selectivity to conjugational specificity
    • Nagy V, Dikic I (2010) Ubiquitin ligase complexes: From substrate selectivity to conjugational specificity. Biol Chem 391:163-169.
    • (2010) Biol Chem , vol.391 , pp. 163-169
    • Nagy, V.1    Dikic, I.2
  • 13
    • 0032576777 scopus 로고    scopus 로고
    • Regulation of the Hedgehog and Wingless signalling pathways by the F- box/WD40-repeat protein Slimb
    • DOI 10.1038/35154
    • Jiang J, Struhl G (1998) Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb. Nature 391:493-496. (Pubitemid 28086550)
    • (1998) Nature , vol.391 , Issue.6666 , pp. 493-496
    • Jiang, J.1    Struhl, G.2
  • 16
    • 33745809820 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells
    • DOI 10.1074/jbc.M600831200
    • Yang J, et al. (2006) Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells. J Biol Chem 281:17751-17757. (Pubitemid 44035574)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.26 , pp. 17751-17757
    • Yang, J.1    Zhang, W.2    Evans, P.M.3    Chen, X.4    He, X.5    Liu, C.6
  • 18
    • 62349124503 scopus 로고    scopus 로고
    • Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of beta-catenin/Arm and stimulation of target gene expression
    • Lee W, Swarup S, Chen J, Ishitani T, Verheyen EM (2009) Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of beta-catenin/Arm and stimulation of target gene expression. Development 136:241-251.
    • (2009) Development , vol.136 , pp. 241-251
    • Lee, W.1    Swarup, S.2    Chen, J.3    Ishitani, T.4    Verheyen, E.M.5
  • 19
    • 0028345607 scopus 로고
    • The wingless signalling pathway and the patterning of the wing margin in Drosophila
    • Couso JP, Bishop SA, Martinez Arias A (1994) The wingless signalling pathway and the patterning of the wing margin in Drosophila. Development 120:621-636. (Pubitemid 24071204)
    • (1994) Development , vol.120 , Issue.3 , pp. 621-636
    • Couso, J.P.1    Bishop, S.A.2    Martinez, A.A.3
  • 22
    • 0033529667 scopus 로고    scopus 로고
    • Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression
    • Chen CH, et al. (1999) Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression. Cell 98:305-316.
    • (1999) Cell , vol.98 , pp. 305-316
    • Chen, C.H.1
  • 23
    • 0029027783 scopus 로고
    • Analysis of cubitus interruptus regulation in Drosophila embryos and imaginal disks
    • Schwartz C, Locke J, Nishida C, Kornberg TB (1995) Analysis of cubitus interruptus regulation in Drosophila embryos and imaginal disks. Development 121:1625-1635.
    • (1995) Development , vol.121 , pp. 1625-1635
    • Schwartz, C.1    Locke, J.2    Nishida, C.3    Kornberg, T.B.4
  • 24
    • 0031587830 scopus 로고    scopus 로고
    • Proteolysis that is inhibited by hedgehog targets cubitus interruptus protein to the nucleus and converts it to a repressor
    • Aza-Blanc P, Ramírez-Weber FA, Laget MP, Schwartz C, Kornberg TB (1997) Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor. Cell 89:1043-1053. (Pubitemid 127678738)
    • (1997) Cell , vol.89 , Issue.7 , pp. 1043-1053
    • Aza-Blanc, P.1    Ramirez-, W.F.-A.2    Laget, M.-P.3    Schwartz, C.4    Kornberg, T.B.5
  • 25
    • 0027788042 scopus 로고
    • The TGF beta homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina
    • Heberlein U, Wolff T, Rubin GM (1993) The TGF beta homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina. Cell 75:913-926.
    • (1993) Cell , vol.75 , pp. 913-926
    • Heberlein, U.1    Wolff, T.2    Rubin, G.M.3
  • 26
    • 0037155737 scopus 로고    scopus 로고
    • Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1
    • DOI 10.1016/S0092-8674(02)00664-5
    • Price MA, Kalderon D (2002) Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1. Cell 108:823-835. (Pubitemid 34327533)
    • (2002) Cell , vol.108 , Issue.6 , pp. 823-835
    • Price, M.A.1    Kalderon, D.2
  • 27
    • 0037041470 scopus 로고    scopus 로고
    • Shaggy/GSK3 antagonizes hedgehog signalling by regulating Cubitus interruptus
    • DOI 10.1038/nature733
    • Jia J, et al. (2002) Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus. Nature 416:548-552. (Pubitemid 34288858)
    • (2002) Nature , vol.416 , Issue.6880 , pp. 548-552
    • Jia, J.1    Amanai, K.2    Wang, G.3    Tang, J.4    Wang, B.5    Jiang, J.6
  • 28
    • 77957876629 scopus 로고    scopus 로고
    • Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification
    • Hikasa H, et al. (2010) Regulation of TCF3 by Wnt-dependent phosphorylation during vertebrate axis specification. Dev Cell 19:521-532.
    • (2010) Dev Cell , vol.19 , pp. 521-532
    • Hikasa, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.