-
1
-
-
75449094816
-
Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications
-
Fabbrini, E., Sullivan, S., Klein, S. Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology 2010, 51, 679-689.
-
(2010)
Hepatology
, vol.51
, pp. 679-689
-
-
Fabbrini, E.1
Sullivan, S.2
Klein, S.3
-
2
-
-
0036114844
-
Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy
-
Petersen, K. F., Oral, E. A., Dufour, S., Befroy, D. et al., Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J. Clin. Invest. 2002, 109, 1345-1350.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1345-1350
-
-
Petersen, K.F.1
Oral, E.A.2
Dufour, S.3
Befroy, D.4
-
3
-
-
14644435731
-
Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes
-
Petersen, K. F., Dufour, S., Befroy, D., Lehrke, M. et al., Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes. Diabetes 2005, 54, 603-608.
-
(2005)
Diabetes
, vol.54
, pp. 603-608
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Lehrke, M.4
-
4
-
-
15444364990
-
Acquired obesity is associated with increased liver fat, intra-abdominal fat, and insulin resistance in young adult monozygotic twins
-
Pietilainen, K. H., Rissanen, A., Kaprio, J., Makimattila, S. et al., Acquired obesity is associated with increased liver fat, intra-abdominal fat, and insulin resistance in young adult monozygotic twins. Am. J. Physiol. Endocrinol. Metab. 2005, 288, E768-E774.
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.288
-
-
Pietilainen, K.H.1
Rissanen, A.2
Kaprio, J.3
Makimattila, S.4
-
5
-
-
3543029821
-
Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease
-
Samuel, V. T., Liu, Z. X., Qu, X., Elder, B. D. et al., Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. J. Biol. Chem. 2004, 279, 32345-32353.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 32345-32353
-
-
Samuel, V.T.1
Liu, Z.X.2
Qu, X.3
Elder, B.D.4
-
6
-
-
33847404482
-
Inhibition of protein kinase C epsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease
-
Samuel, V. T., Liu, Z. X., Wang, A., Beddow, S. A. et al., Inhibition of protein kinase C epsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. J. Clin. Invest. 2007, 117, 739-745.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 739-745
-
-
Samuel, V.T.1
Liu, Z.X.2
Wang, A.3
Beddow, S.A.4
-
7
-
-
0030791050
-
Effect of conjugated linoleic acid on body composition in mice
-
Park, Y., Albright, K. J., Liu, W., Storkson, J. M. et al., Effect of conjugated linoleic acid on body composition in mice. Lipids 1997, 32, 853-858.
-
(1997)
Lipids
, vol.32
, pp. 853-858
-
-
Park, Y.1
Albright, K.J.2
Liu, W.3
Storkson, J.M.4
-
8
-
-
0033861304
-
Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice
-
Tsuboyama-Kasaoka, N., Takahashi, M., Tanemura, K., Kim, H. J. et al., Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice. Diabetes 2000, 49, 1534-1542.
-
(2000)
Diabetes
, vol.49
, pp. 1534-1542
-
-
Tsuboyama-Kasaoka, N.1
Takahashi, M.2
Tanemura, K.3
Kim, H.J.4
-
9
-
-
16244396154
-
Supplementation with conjugated linoleic acid for 24 months is well tolerated by and reduces body fat mass in healthy, overweight humans
-
Gaullier, J. M., Halse, J., Hoye, K., Kristiansen, K. et al., Supplementation with conjugated linoleic acid for 24 months is well tolerated by and reduces body fat mass in healthy, overweight humans. J. Nutr. 2005, 135, 778-784.
-
(2005)
J. Nutr.
, vol.135
, pp. 778-784
-
-
Gaullier, J.M.1
Halse, J.2
Hoye, K.3
Kristiansen, K.4
-
10
-
-
70349565003
-
Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus
-
Norris, L. E., Collene, A. L., Asp, M. L., Hsu, J. C. et al., Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus. Am. J. Clin. Nutr. 2009, 90, 468-476.
-
(2009)
Am. J. Clin. Nutr.
, vol.90
, pp. 468-476
-
-
Norris, L.E.1
Collene, A.L.2
Asp, M.L.3
Hsu, J.C.4
-
11
-
-
0032955643
-
Evidence that the trans-10, cis-12 isomer of conjugated linoleic acid induces body composition changes in mice
-
Park, Y., Storkson, J. M., Albright, K. J., Liu, W., Pariza, M. W., Evidence that the trans-10, cis-12 isomer of conjugated linoleic acid induces body composition changes in mice. Lipids 1999, 34, 235-241.
-
(1999)
Lipids
, vol.34
, pp. 235-241
-
-
Park, Y.1
Storkson, J.M.2
Albright, K.J.3
Liu, W.4
Pariza, M.W.5
-
12
-
-
0034858073
-
Trans-10, cis-12, but not cis-9, trans-11, conjugated linoleic acid attenuates lipogenesis in primary cultures of stromal vascular cells from human adipose tissue
-
Brown, J. M., Halvorsen, Y. D., Lea-Currie, Y. R., Geigerman, C., McIntosh, M., Trans-10, cis-12, but not cis-9, trans-11, conjugated linoleic acid attenuates lipogenesis in primary cultures of stromal vascular cells from human adipose tissue. J. Nutr. 2001, 131, 2316-2321.
-
(2001)
J. Nutr.
, vol.131
, pp. 2316-2321
-
-
Brown, J.M.1
Halvorsen, Y.D.2
Lea-Currie, Y.R.3
Geigerman, C.4
McIntosh, M.5
-
13
-
-
0036739536
-
Dietary trans-10,cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse
-
Clement, L., Poirier, H., Niot, I., Bocher, V. et al., Dietary trans-10, cis-12 conjugated linoleic acid induces hyperinsulinemia and fatty liver in the mouse. J. Lipid Res. 2002, 43, 1400-1409.
-
(2002)
J. Lipid Res.
, vol.43
, pp. 1400-1409
-
-
Clement, L.1
Poirier, H.2
Niot, I.3
Bocher, V.4
-
14
-
-
0031056451
-
Conjugated linoleic acid modulates hepatic lipid composition in mice
-
Belury, M. A., Kempa-Steczko, A., Conjugated linoleic acid modulates hepatic lipid composition in mice. Lipids 1997, 32, 199-204.
-
(1997)
Lipids
, vol.32
, pp. 199-204
-
-
Belury, M.A.1
Kempa-Steczko, A.2
-
15
-
-
0037426318
-
Activity and mRNA levels of enzymes involved in hepatic fatty acid synthesis and oxidation in mice fed conjugated linoleic acid
-
Takahashi, Y., Kushiro, M. Shinohara, K., Ide, T., Activity and mRNA levels of enzymes involved in hepatic fatty acid synthesis and oxidation in mice fed conjugated linoleic acid. Biochim. Biophys. Acta 2003, 1631, 265-273.
-
(2003)
Biochim. Biophys. Acta
, vol.1631
, pp. 265-273
-
-
Takahashi, Y.1
Kushiro, M.2
Shinohara, K.3
Ide, T.4
-
16
-
-
34447499065
-
Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice
-
Liu, L. F., Purushotham, A., Wendel, A. A., Belury, M. A., Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice. Am. J. Physiol. Gastrointest. Liver Physiol. 2007, 292, G1671-G1682.
-
(2007)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.292
-
-
Liu, L.F.1
Purushotham, A.2
Wendel, A.A.3
Belury, M.A.4
-
17
-
-
12744262842
-
Interaction of fish oil and conjugated linoleic acid in affecting hepatic activity of lipogenic enzymes and gene expression in liver and adipose tissue
-
Ide, T., Interaction of fish oil and conjugated linoleic acid in affecting hepatic activity of lipogenic enzymes and gene expression in liver and adipose tissue. Diabetes 2005, 54, 412-423.
-
(2005)
Diabetes
, vol.54
, pp. 412-423
-
-
Ide, T.1
-
18
-
-
1842530442
-
Hepatic steatosis is not due to impaired fatty acid oxidation capacities in C57BL/6J mice fed the conjugated trans-10,cis-12-isomer of linoleic acid
-
Degrace, P., Demizieux, L., Gresti, J., Chardigny, J. M. et al., Hepatic steatosis is not due to impaired fatty acid oxidation capacities in C57BL/6J mice fed the conjugated trans-10, cis-12-isomer of linoleic acid. J. Nutr. 2004, 134, 861-867.
-
(2004)
J. Nutr.
, vol.134
, pp. 861-867
-
-
Degrace, P.1
Demizieux, L.2
Gresti, J.3
Chardigny, J.M.4
-
19
-
-
70449158340
-
A simple method for the isolation and purification of total lipides from animal tissues
-
Folch, J., Lees, M., Sloan Stanley, G. H. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 1957, 226, 497-509.
-
(1957)
J. Biol. Chem.
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloan Stanley, G.H.3
-
20
-
-
0344110544
-
Determination of the molecular species composition of diacylglycerols in human adipose tissue by solid-phase extraction and gas chromatography on a polar phase
-
Pacheco, Y. M., Perez-Camino, M. C., Cert, A., Montero, E., Ruiz-Gutierrez, V., Determination of the molecular species composition of diacylglycerols in human adipose tissue by solid-phase extraction and gas chromatography on a polar phase. J. Chromatogr. B Biomed. Sci. Appl. 1998, 714, 127-132.
-
(1998)
J. Chromatogr. B Biomed. Sci. Appl.
, vol.714
, pp. 127-132
-
-
Pacheco, Y.M.1
Perez-Camino, M.C.2
Cert, A.3
Montero, E.4
Ruiz-Gutierrez, V.5
-
21
-
-
0036785633
-
Free fatty acid-induced hepatic insulin resistance: a potential role for protein kinase C-delta
-
Lam, T. K., Yoshii, H., Haber, C. A., Bogdanovic, E. et al., Free fatty acid-induced hepatic insulin resistance: a potential role for protein kinase C-delta. Am. J. Physiol. Endocrinol. Metab. 2002, 283, E682-E691.
-
(2002)
Am. J. Physiol. Endocrinol. Metab.
, vol.283
-
-
Lam, T.K.1
Yoshii, H.2
Haber, C.A.3
Bogdanovic, E.4
-
22
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak, K. J., Schmittgen, T. D., Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25, 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
23
-
-
0141446024
-
Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
-
Gavrilova, O., Haluzik, M., Matsusue, K., Cutson, J. J. et al., Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J. Biol. Chem. 2003, 278, 34268-34276.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34268-34276
-
-
Gavrilova, O.1
Haluzik, M.2
Matsusue, K.3
Cutson, J.J.4
-
24
-
-
0029797604
-
Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a
-
Shimano, H., Horton, J. D., Hammer, R. E., Shimomura, I. et al., Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. J. Clin. Invest. 1996, 98, 1575-1584.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1575-1584
-
-
Shimano, H.1
Horton, J.D.2
Hammer, R.E.3
Shimomura, I.4
-
25
-
-
0037977719
-
Increasing the amount of fat in a conjugated linoleic acid-supplemented diet reduces lipodystrophy in mice
-
Tsuboyama-Kasaoka, N., Miyazaki, H., Kasaoka, S., Ezaki, O., Increasing the amount of fat in a conjugated linoleic acid-supplemented diet reduces lipodystrophy in mice. J. Nutr. 2003, 133, 1793-1799.
-
(2003)
J. Nutr.
, vol.133
, pp. 1793-1799
-
-
Tsuboyama-Kasaoka, N.1
Miyazaki, H.2
Kasaoka, S.3
Ezaki, O.4
-
26
-
-
38049120884
-
Conjugated linoleic acid fails to worsen insulin resistance but induces hepatic steatosis in the presence of leptin in ob/ob mice
-
Wendel, A. A., Purushotham, A., Liu, L. F., Belury, M. A., Conjugated linoleic acid fails to worsen insulin resistance but induces hepatic steatosis in the presence of leptin in ob/ob mice. J. Lipid Res. 2008, 49, 98-106.
-
(2008)
J. Lipid Res.
, vol.49
, pp. 98-106
-
-
Wendel, A.A.1
Purushotham, A.2
Liu, L.F.3
Belury, M.A.4
-
27
-
-
4043101702
-
Separate contribution of diabetes, total fat mass, and fat topography to glucose production, gluconeogenesis, and glycogenolysis
-
Gastaldelli, A., Miyazaki, Y., Pettiti, M. Buzzigoli, E. et al., Separate contribution of diabetes, total fat mass, and fat topography to glucose production, gluconeogenesis, and glycogenolysis. J. Clin. Endocrinol. Metab. 2004, 89, 3914-3921.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 3914-3921
-
-
Gastaldelli, A.1
Miyazaki, Y.2
Pettiti, M.3
Buzzigoli, E.4
-
28
-
-
67749142348
-
Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 diabetes
-
Samuel, V. T., Beddow, S. A., Iwasaki, T., Zhang, X. M. et al., Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 diabetes. Proc. Natl. Acad. Sci. USA 2009, 106, 12121-12126.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12121-12126
-
-
Samuel, V.T.1
Beddow, S.A.2
Iwasaki, T.3
Zhang, X.M.4
-
29
-
-
0023834876
-
Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity
-
Takayama, S., White, M. F., Kahn, C. R., Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity. J. Biol. Chem. 1988, 263, 3440-3447.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 3440-3447
-
-
Takayama, S.1
White, M.F.2
Kahn, C.R.3
-
30
-
-
0033517284
-
Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy
-
Shimomura, I., Hammer, R. E. Ikemoto, S. Brown, M. S. Goldstein, J. L., Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. Nature 1999, 401, 73-76.
-
(1999)
Nature
, vol.401
, pp. 73-76
-
-
Shimomura, I.1
Hammer, R.E.2
Ikemoto, S.3
Brown, M.S.4
Goldstein, J.L.5
-
31
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi, T., Kamon, J., Waki, H., Terauchi, Y. et al., The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat. Med. 2001, 7, 941-946.
-
(2001)
Nat. Med.
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Terauchi, Y.4
-
32
-
-
70349238777
-
Adipokines in liver diseases
-
Marra, F., Bertolani, C. Adipokines in liver diseases. Hepatology 2009, 50, 957-969.
-
(2009)
Hepatology
, vol.50
, pp. 957-969
-
-
Marra, F.1
Bertolani, C.2
-
33
-
-
42949100989
-
The trans-10, cis-12 isomer of conjugated linoleic acid decreases adiponectin assembly by PPARgamma-dependent and PPARgamma-independent mechanisms
-
Miller, J. R., Siripurkpong, P., Hawes, J., Majdalawieh, A. et al., The trans-10, cis-12 isomer of conjugated linoleic acid decreases adiponectin assembly by PPARgamma-dependent and PPARgamma-independent mechanisms. J. Lipid Res. 2008, 49, 550-562.
-
(2008)
J. Lipid Res.
, vol.49
, pp. 550-562
-
-
Miller, J.R.1
Siripurkpong, P.2
Hawes, J.3
Majdalawieh, A.4
-
34
-
-
33748291462
-
Nutritional supplementation with trans-10, cis-12-conjugated linoleic acid induces inflammation of white adipose tissue
-
Poirier, H., Shapiro, J. S., Kim, R. J., Lazar, M. A., Nutritional supplementation with trans-10, cis-12-conjugated linoleic acid induces inflammation of white adipose tissue. Diabetes 2006, 55, 1634-1641.
-
(2006)
Diabetes
, vol.55
, pp. 1634-1641
-
-
Poirier, H.1
Shapiro, J.S.2
Kim, R.J.3
Lazar, M.A.4
-
35
-
-
33846877211
-
Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice
-
Purushotham, A., Wendel, A. A., Liu, L. F., Belury, M. A., Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice. J. Lipid Res. 2007, 48, 444-452.
-
(2007)
J. Lipid Res.
, vol.48
, pp. 444-452
-
-
Purushotham, A.1
Wendel, A.A.2
Liu, L.F.3
Belury, M.A.4
|