A novel sterol 14α-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily

Journal of Biological Chemistry

Volumn 277, Issue 49, 2002, Pages 46959-46965

  Jackson, Colin J ^a   Lamb, David C ^a   Marczylo, Timothy H ^a   Warrilow, Andrew G S ^a   Manning, Nigel J ^b   Lowe, David J ^c   Kelly, Diane E ^a   Kelly, Steven L ^a  

^a ABERYSTWYTH UNIVERSITY   (United Kingdom)

^b SHEFFIELD CHILDREN S HOSPITAL   (United Kingdom)

^c JOHN INNES CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOSYNTHESIS; ESCHERICHIA COLI; GAS CHROMATOGRAPHY; GENES; MASS SPECTROMETRY;

STEROL BIOSYNTHESIS;

ENZYMES;

BACTERIAL ENZYME; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; FERREDOXIN; HYBRID PROTEIN; LANOSTEROL; OXIDOREDUCTASE; PROTEIN MCCYP51FX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STEROL 14ALPHA DEMETHYLASE; UNCLASSIFIED DRUG; CARBON MONOXIDE; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; LANOSTEROL 14 ALPHA-DEMETHYLASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVITY; ENZYME STRUCTURE; GAS CHROMATOGRAPHY; GENE SEQUENCE; MASS SPECTROMETRY; METHYLOCOCCUS CAPSULATUS; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PURIFICATION; SEQUENCE HOMOLOGY; STEROL SYNTHESIS; AMINO ACID SEQUENCE; CHEMISTRY; ELECTRON SPIN RESONANCE; ENZYME SPECIFICITY; ESCHERICHIA COLI; GEL CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; METHYLOCOCCUS CAPSULATUS; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; PROTEOBACTERIA;

AMINO ACID SEQUENCE; BASE SEQUENCE; CARBON MONOXIDE; CHROMATOGRAPHY, GEL; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; FERREDOXIN-NADP REDUCTASE; FERREDOXINS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; METHYLOCOCCUS CAPSULATUS; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 0037032543     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M203523200     Document Type: Article

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