Efficacy of pharmacological estrogen receptor antagonists in blocking activation of zebrafish estrogen receptors

General and Comparative Endocrinology

Volumn 173, Issue 1, 2011, Pages 183-189

  Notch, Emily G ^a,b   Mayer, Gregory D ^c  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MAINE   (United States)

^c TEXAS TECH UNIVERSITY   (United States)

Author keywords

17 Ethinylestradiol; Estrogen receptor; ICI 182, 780; MPP dihydrochloride; PHTPP; Zebrafish

Indexed keywords

COMPLEMENTARY DNA; ESTRADIOL; ESTROGEN RECEPTOR 2A; ESTROGEN RECEPTOR 2B; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ETHINYLESTRADIOL; FULVESTRANT; ISOPROTEIN; LUCIFERASE; METHYL PIPERIDINO PYRAZOLE; PYRAZOLO[1,5 A]PYRIMIDINE DERIVATIVE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; STEROID HORMONE RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVITY; ESTROGEN RECEPTOR 2A GENE; ESTROGEN RECEPTOR 2B GENE; ESTROGEN RECEPTOR ALPHA GENE; GENETIC TRANSFECTION; LIGAND BINDING; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR GENE; ZEBRA FISH;

EID: 79959917205     PISSN: 00166480     EISSN: 10956840     Source Type: Journal    
DOI: 10.1016/j.ygcen.2011.05.008     Document Type: Article

References (29)

1. Bardet P.L., Horard B., Robinson-Rechavi M., Laudet V., Vanacker J.M. Characterization of oestrogen receptors in zebrafish (Danio rerio). J. Mol. Endocrinol. 2002, 28:153-163.
2. Barkhem T., Carlsson B., Nilsson Y., Enmark E., Gustafsson J.A., Nilsson S. Differential response of estrogen receptor alpha and estrogen receptor beta to partial estrogen agonists/antagonists. Mol. Pharmacol. 1998, 54:105-112.
3. Compton D.R., Sheng S.B., Carlson K.E., Rebacz N.A., Lee I.Y., Katzenellenbogen B.S., Katzenellenbogen J.A. Pyrazolo[15-a]pyrimidines: Estrogen receptor ligands possessing estrogen receptor beta antagonist activity. J. Med. Chem. 2004, 47:5872-5893.
4. Dang Z. Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications. Toxicol. Lett. 2010, 192:298-315.
5. Davis L.K., Katsu Y., Iguchi T., Lerner D.T., Hirano T., Grau E.G. Transcriptional activity and biological effects of mammalian estrogen receptor ligands on three hepatic estrogen receptors in Mozambique tilapia. J. Steroid Biochem. Mol. Biol. 2010, 122:272-278.
6. Denny J.S., Tapper M.A., Schmieder P.K., Hornung M.W., Jensen K.M., Ankley G.T., Henry T.R. Comparison of relative binding affinities of endocrine active compounds to fathead minnow and rainbow trout estrogen receptors. Environ. Toxicol. Chem. 2005, 24:2948-2953.
7. Evans R.M. The steroid and thyroid-hormone receptor superfamily. Science 1988, 240:889-895.
8. Filby A.L., Thorpe K.L., Tyler C.R. Multiple molecular effect pathways of an environmental oestrogen in fish. J. Mol. Endocrinol. 2006, 37:121-134.
9. Filby A.L., Tyler C.R. Molecular characterization of estrogen receptors 1, 2a and 2b and their tissue and ontogenic expression profiles in fathead minnow (Pimephales promelas). Biol. Reprod. 2005, 73:648-662.
10. Gutendorf B., Westendorf J. Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural synthetic estrogens, phytoestrogens and xenoestrogens. Toxicology 2001, 166:79-89.
11. Hall J.M., McDonnell D.P. The estrogen receptor beta-isoform (ER beta) of the human estrogen receptor modulates ER alpha transcriptional activity and is a key regulator of the cellular response to estrogens and antiestrogens. Endocrinology 1999, 140:5566-5578.
12. Hawkins M.B., Thomas P. The unusual binding properties of the third distinct teleost estrogen receptor subtype ER beta a are accompanied by highly conserved amino acid changes in the ligand binding domain. Endocrinology 2004, 145:2968-2977.
13. Hawkins M.B., Thornton J.W., Crews D., Skipper J.K., Dotte A., Thomas P. Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:10751-10756.
14. Hermenegildo C., Cano A. Pure anti-oestrogens. Human Reprod. Update 2000, 6:237-243.
15. Hornung M.W., Ankley G.T., Schmieder P.K. Induction of an estrogen-responsive reporter gene in rainbow trout hepatoma cells (RTH 149) at 11 or 18°C. Environ. Toxicol. Chem. 2003, 22:866-871.
16. Katsu Y., Lange A., Urushitani H., Ichikawa R., Paull G.C., Cahill L.L., Jobling S., Tyler C.R., Iguchi T. Functional associations between two estrogen receptors, environmental estrogens, and sexual disruption in the roach (Rutilus rutilus). Environ. Sci. Technol. 2007, 41:3368-3374.
17. B.S. Katzenellenbogen, J. Sun, W.R. Harrington, D.M. Kraichely, D. Ganessunker, J.A. Katzenellenbogen, Structure-function relationships in estrogen receptors and the characterization of novel selective estrogen receptor modulators with unique pharmacological profiles, in: M. Anthony, B.K. Dunn, S. Sherman (Eds.), Selective Estrogen Receptor Modulators, vol. 949, Annals New York Academy of Sciences, 2001, pp. 6-15.
18. Leanos-Castaneda O., Van der Kraak G. Functional characterization of estrogen receptor subtypes, ER alpha and ER beta, mediating vitellogenin production in the liver of rainbow trout. Toxicol. Appl. Pharmacol. 2007, 224:116-125.
19. Legler J., Zeinstra L.M., Schuitemaker F., Lanser P.H., Bogerd J., Brouwer A., Vethaak A.D., De Voogt P., Murk A.J., van der Burg B. Comparison of in vivo and in vitro reporter gene assays for short-term screening of estrogenic activity. Environ. Sci. Technol. 2002, 36:4410-4415.
20. Menuet A., Pellegrini E., Anglade I., Blaise O., Laudet V., Kah O., Pakdel F. Molecular characterization of three estrogen receptor forms in zebrafish: binding characteristics, transactivation properties, and tissue distributions. Biol. Reprod. 2002, 66:1881-1892.
21. Moggs J.G., Orphanides G. Estrogen receptors: orchestrators of pleiotropic cellular responses. EMBO Rep. 2001, 2:775-781.
22. Moore J.T., McKee D.D., Slentz-Kesler K., Moore L.B., Jones S.A., Horne E.L., Su J.L., Kliewer S.A., Lehmann J.M., Willson T.M. Cloning and characterization of human estrogen receptor beta isoforms. Biochem. Biophys. Res. Commun. 1998, 247:75-78.
23. Nelson E.R., Habibi H.R. Functional significance of nuclear estrogen receptor subtypes in the liver of goldfish. Endocrinology 2010, 151:1668-1676.
24. Pinto P.I.S., Singh P.B., Condeca J.B., Teodosio H.R., Power D.M., Canario A.V.M. ICI 182, 780 has agonistic effects and synergizes with estradiol-17 beta in fish liver, but not in testis. Reprod. Biol. Endocrinol. 2006, 4. 10.1186/1477-7827-4-67.
25. Routledge E.J., White R., Parker M.G., Sumpter J.P. Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ER beta. J. Biol. Chem. 2000, 275:35986-35993.
26. Sabo-Attwood T., Blum J.L., Kroll K.J., Patel V., Birkhoiz D., Szabo N.J., Fisher S.Z., McKenna R., Campbell-Thompson M., Denslow N.D. Distinct expression and activity profiles of largemouth bass (Micropterus salmoides) estrogen receptors in response to estradiol and nonylphenol. J. Mol. Endocrinol. 2007, 39:223-237.
27. Sassi-Messai S., Gibert Y., Bernard L., Nishio S., Ferri Lagneau K., Molina J., Andersson-Lendahl M., Benoit G., Balaguer P., Laudet V. The phytoestrogen genistein affects zebrafish development through two different pathways. PLoS ONE 2009, 4:e4935.
28. Sun J., Huang Y.R., Harrington W.R., Sheng S.B., Katzenellenbogen J.A., Katzenellenbogen B.S. Antagonists selective for estrogen receptor alpha. Endocrinology 2002, 143:941-947.
29. Wjayaratne A., Nagel S., Paige L., Christensen D., Norris J., Fowlkes D., McDonnell D. Comparative analyses of mechanistic differences among antiestrogens. Endocrinology 1999, 140:5828-5840.