Determination of zoledronic acid in human urine and blood plasma using liquid chromatography/electrospray mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 22, 2011, Pages 2073-2080

  Veldboer, Katrin ^a   Vielhaber, Torsten ^a   Ahrens, Helmut ^b   Hardes, Jendrik ^b   Streitbürger, Arne ^b   Karst, Uwe ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Bisphosphonates; Derivatisation; Deuterated internal standards; Electrospray mass spectrometry; Liquid chromatography; Zoledronic acid

Indexed keywords

BISPHOSPHONATES; DERIVATISATION; ELECTROSPRAY MASS SPECTROMETRY; INTERNAL STANDARDS; ZOLEDRONIC ACID;

DEUTERIUM; ISOMERS; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; PHOSPHORIC ACID;

BLOOD;

DEUTERIUM; DIAZOMETHANE; TRIMETHYLSILYL DERIVATIVE; TRIMETHYLSILYL DIAZOMETHANE; UNCLASSIFIED DRUG; ZOLEDRONIC ACID;

ARTICLE; BLOOD ANALYSIS; CALIBRATION; CONTROLLED STUDY; DERIVATIZATION; DRUG BLOOD LEVEL; DRUG URINE LEVEL; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; OSTEOPOROSIS; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SINGLE DRUG DOSE; URINALYSIS;

BONE DENSITY CONSERVATION AGENTS; CHROMATOGRAPHY, LIQUID; DIAZOMETHANE; DIPHOSPHONATES; FEMALE; HUMANS; IMIDAZOLES; LINEAR MODELS; OSTEOPOROSIS; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRIMETHYLSILYL COMPOUNDS;

EID: 79959883230     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.05.037     Document Type: Article

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