Effects of food on a gastrically degraded drug: Azithromycin fast-dissolving gelatin capsules and HPMC capsules

Pharmaceutical Research

Volumn 28, Issue 7, 2011, Pages 1531-1539

  Curatolo, William ^a,c   Liu, Ping ^b   Johnson, Barbara A ^a   Hausberger, Angela ^a   Quan, Ernest ^a   Vendola, Thomas ^a   Vatsaraj, Neha ^a   Foulds, George ^a   Vincent, John ^b   Chandra, Richa ^b  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^b PFIZER INC   (United States)

^c Bayberry Institute   (United States)

Author keywords

azithromycin; capsules; des cladinose azithromycin; food effect; HPMC capsules

Indexed keywords

AZITHROMYCIN; CROSCARMELLOSE SODIUM; ENSURE; STARCH GLYCOLATE SODIUM;

AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG DEGRADATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG SOLUBILITY; DRUG STRUCTURE; FOOD DRUG INTERACTION; HUMAN; HUMAN EXPERIMENT; LIPID DIET; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; AZITHROMYCIN; BIOLOGICAL AVAILABILITY; CAPSULES; CROSS-OVER STUDIES; FOOD; GASTRIC ACID; GELATIN; HUMANS; HYDROGEN-ION CONCENTRATION; METHYLCELLULOSE; MOLECULAR STRUCTURE;

EID: 79959875536     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0386-9     Document Type: Article

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