The absence of an effect of food on the bioavailability of azithromycin administered as tablets, sachet or suspension

Journal of Antimicrobial Chemotherapy

Volumn 37, Issue SUPPL. C, 1996, Pages 37-44

  Foulds, G ^a   Luke, D R ^a   Teng, R ^a   Willavize, S A ^a   Friedman, H ^a   Curatolo, W J ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN; MACROLIDE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; FOOD INTAKE; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; RANDOMIZED CONTROLLED TRIAL;

EID: 0029809636     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/37.suppl_c.37     Document Type: Article

References (15)

1. Anthone, G. J., Wang, B. H., Zinner, M. J. & Yeo, C. J. (1992). Site-specific variations in basal and meal-stimulated intestinal absorption. Journal of Surgical Research 52, 454-8.
2. Bergan, T., Jorgansen, N. P., Olszewski, W. & Zhang, Y. (1992). Azithromycin pharmacokinetics and penetration to lymph. Scandinavian Journal of Infectious Diseases Suppl. 83, 15-21.
3. Bright, G. M., Nagel, A. A., Bordner, J., Desai, K. A., Dibrino, J. N., Nowakowska, J. et al. (1988). Synthesis, in vitro and in vivo activity of novel 9-deoxo-9a-AZA-9a-homoerythromycin A derivatives: a new class of macrolide antibiotics, the azalides. Journal of Antibiotics 41, 1029-47.
4. Chu, S.-Y., Park, Y., Locke, C., Wilson, D. S. & Cavanaugh, J. C. (1992). Drug-food interaction potential of clarithromycin, a new macrolide antimicrobial. Journal of Clinical Pharmacology 32, 32-6.
5. Coyne, T. C., Shum, S., Chun, A. H., Jeansonne, L. & Shirkey, H. C. (1978). Bioavailability of erythromycin ethylsuccinate in pediatric patients. Journal of Clinical Pharmacology 18, 194-202.
6. Edelbroek, M. A. L., Horowitz, M., Wishart, J. M. & Akkermans, L. M. (1993). Effects of erythromycin on gastric emptying, alcohol absorption and small intestinal transit in normal subjects. Journal of Nuclear Medicine 34, 582-8.
7. Foulds, G. & Johnson, R. B. (1993). Selection of dose regimens of azithromycin. Journal of Antimicrobial Chemotherapy 31, Suppl. E, 39-50.
8. Foulds, G., Shepard, R. M. & Johnson, R. B. (1990). The pharmacokinetics of azithromycin in human serum and tissues. Journal of Antimicrobial Chemotherapy 25, Suppl. A, 73-82.
9. Gardner, M. J. & Ronfeld, R. A. (1992). Interpretation/characterization of the pharmacokinetics of azithromycin in man. In Program and Abstracts of the Eighth Mediterranean Congress of Chemotherapy, Athens, 1992. Abstract 407, p. 302. Mediterranean Society of Chemotherapy.
10. Go, Y. L., Hoffman, A. F. & Summerskill, W. H. (1970). Pancreozymin bioassay in man based on pancreatic enzyme secretion: potency of specific amino acids and other digestive products. Journal of Clinical Investigation 49, 1558-64.
11. Gustavson, L. E., Chu, S.-Y., Locke, C. F. & Craft, J. C. (1994). Pharmacokinetic profile of clarithromycin in children: an overview. In Abstracts and Proceedings of the Second International Conference on Macrolides, Azalides and Streptogrammins, Venice, 1994. Abstract 204. Wallace Communications, Atlanta, GA.
12. Physicians Desk Reference (1995). Zithromax, pp. 1881-3. Medical Economics Data Production Company, Montvale, NJ.
13. Retsema, J., Girard, A., Shelkly, W., Manousos, M., Anderson, M., Bright, G. et al. (1987). Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against Gram-negative organisms. Antimicrobial Agents and Chemotherapy 31, 1939-47.
14. Shepard, R. M., Duthu, G. S., Ferraina, R. A. & Mullins, M. A. (1991). High-performance liquid Chromatographic assay with electrochemical detection of azithromycin in serum and tissues. Journal of Chemotherapy 565, 321-37.
15. Welling, P. G. & Tse, F. L. (1982). The influence of food on the absorption of antimicrobial agents. Journal of Antimicrobial Chemotherapy 9, 7-27.