Redox-dependent oligomerization through a leucine zipper motif is essential for MG53-mediated cell membrane repair

American Journal of Physiology - Cell Physiology

Volumn 301, Issue 1, 2011, Pages

  Hwang, Moonsun ^a   Ko, Jae kyun ^a   Weisleder, Noah ^a   Takeshima, Hiroshi ^b   Ma, Jianjie ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Cell membrane resealing; Mitsugumin 53; Plasma membrane repair; Redox state; TRIM72

Indexed keywords

ALANINE; ALKYLATING AGENT; CYSTEINE; GREEN FLUORESCENT PROTEIN; LEUCINE;

ARTICLE; BASIC LEUCINE ZIPPER MOTIF; CELL ACTIVITY; CELL ASSAY; CELL MEMBRANE ACTIVITY; CONTROLLED STUDY; CROSS LINKING; DIMERIZATION; EMBRYO; GENE MUTATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; HYPOTHESIS; IN VIVO STUDY; MOLECULAR INTERACTION; MUTANT; OLIGOMERIZATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN MODIFICATION;

ANIMALS; CARRIER PROTEINS; CAVEOLIN 3; CELL MEMBRANE; CELL NUCLEUS; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; LEUCINE ZIPPERS; MEMBRANE PROTEINS; MICE; MUSCLE PROTEINS; OXIDATION-REDUCTION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; REACTIVE OXYGEN SPECIES; RECOMBINANT FUSION PROTEINS;

ANIMALIA;

EID: 79959857021     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00382.2010     Document Type: Article

References (32)

1. Bansal D, Miyake K, Vogel SS, Groh S, Chen CC, Williamson R, McNeil PL, Campbell KP. Defective membrane repair in dysferlindeficient muscular dystrophy. Nature 423: 168-172, 2003.
2. Barbee KA. Mechanical cell injury. Ann NY Acad Sci 1066: 67-84, 2005.
3. Cai C, Masumiya H, Weisleder N, Matsuda N, Nishi M, Hwang M, Ko JK, Lin P, Thornton A, Zhao X, Pan Z, Komazaki S, Brotto M, Takeshima H, Ma J. MG53 nucleates assembly of cell membrane repair machinery. Nat Cell Biol 11: 56-64, 2009.
4. Cai C, Weisleder N, Ko JK, Komazaki S, Sunada Y, Nishi M, Takeshima H, Ma J. Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3, and dysferlin. J Biol Chem 284: 15894-15902, 2009.
5. Cao CM, Zhang Y, Weisleder N, Ferrante C, Wang X, Lv F, Song R, Hwang M, Jin L, Guo J, Peng W, Li G, Nishi M, Takeshima H, Ma J, Xiao RP. MG53 constitutes a primary determinant of cardiac ischemic preconditioning. Circulation 121: 2565-2574, 2010.
6. Diaz-Griffero F, Qin XR, Hayashi F, Kigawa T, Finzi A, Sarnak Z, Lienlaf M, Yokoyama S, Sodroski J. A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction. J Virol 83: 10737-10751, 2009.
7. Fridlyand LE, Philipson LH. Oxidative reactive species in cell injury: mechanisms in diabetes mellitus and therapeutic approaches. Ann NY Acad Sci 1066: 136-151, 2005.
8. Gack MU, Albrecht RA, Urano T, Inn KS, Huang IC, Carnero E, Farzan M, Inoue S, Jung JU, Garcia-Sastre A. Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I. Cell Host Microbe 5: 439-449, 2009.
9. Glover L, Brown RH Jr. Dysferlin in membrane trafficking and patch repair. Traffic 8: 785-794, 2007.
10. Han R, Campbell KP. Dysferlin and muscle membrane repair. Curr Opin Cell Biol 19: 409-416, 2007.
11. Herscovitch M, Comb W, Ennis T, Coleman K, Yong S, Armstead B, Kalaitzidis D, Chandani S, Gilmore TD. Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347. Biochem Biophys Res Commun 367: 103-108, 2008.
12. Humphries KM, Deal MS, Taylor SS. Enhanced dephosphorylation of cAMP-dependent protein kinase by oxidation and thiol modification. J Biol Chem 280: 2750-2758, 2005.
13. Javanbakht H, Diaz-Griffero F, Yuan W, Yeung DF, Li X, Song B, Sodroski J. The ability of multimerized cyclophilin A to restrict retrovirus infection. Virology 367: 19-29, 2007.
14. Ko JK, Ma J. A rapid and efficient PCR-based mutagenesis method applicable to cell physiology study. Am J Physiol Cell Physiol 288: C1273-C1278, 2005.
15. Lee CS, Yi JS, Jung SY, Kim BW, Lee NR, Choo HJ, Jang SY, Han J, Chi SG, Park M, Lee JH, Ko YG. TRIM72 negatively regulates myogenesis via targeting insulin receptor substrate-1. Cell Death Differ 17: 1254-1265, 2010.
16. Maillard PV, Ecco G, Ortiz M, Trono D. The specificity of TRIM5 alpha-mediated restriction is influenced by its coiled-coil domain. J Virol 84: 5790-5801, 2010.
17. McNeil PL, Kirchhausen T. An emergency response team for membrane repair. Nat Rev Mol Cell Biol 6: 499-505, 2005.
18. Meroni G, Diez-Roux G. TRIM/RBCC, a novel class of 'single protein RING finger' E3 ubiquitin ligases. Bioessays 27: 1147-1157, 2005.
19. Mische CC, Javanbakht H, Song B, Diaz-Griffero F, Stremlau M, Strack B, Si Z, Sodroski J. Retroviral restriction factor TRIM5alpha is a trimer. J Virol 79: 14446-14450, 2005.
20. Miyake K, McNeil PL. Mechanical injury and repair of cells. Crit Care Med 31: S496-S501, 2003.
21. Moylan JS, Reid MB. Oxidative stress, chronic disease, and muscle wasting. Muscle Nerve 35: 411-429, 2007.
22. Peng H, Begg GE, Schultz DC, Friedman JR, Jensen DE, Speicher DW, Rauscher FJ 3rd. Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein-protein interactions. J Mol Biol 295: 1139-1162, 2000.
23. Peng H, Feldman I, Rauscher FJ 3rd. Hetero-oligomerization among the TIF family of RBCC/TRIM domain-containing nuclear cofactors: a potential mechanism for regulating the switch between coactivation and corepression. J Mol Biol 320: 629-644, 2002.
24. Rando TA, Blau HM. Primary mouse myoblast purification, characterization, and transplantation for cell-mediated gene therapy. J Cell Biol 125: 1275-1287, 1994.
25. Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A. The tripartite motif family identifies cell compartments. EMBO J 20: 2140-2151, 2001.
26. Rhodes DA, Trowsdale J. TRIM21 is a trimeric protein that binds IgG Fc via the B30.2 domain. Mol Immunol 44: 2406-2414, 2007.
27. Sambrook J, Fritsch EF, Maniatis editors T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor, 1989.
28. Wang D, Buyon JP, Yang Z, Di Donato F, Miranda-Carus ME, Chan EK. Leucine zipper domain of 52 kDa SS-A/Ro promotes protein dimmer formation and inhibits in vitro transcription activity. Biochim Biophys Acta 1568: 155-161, 2001.
29. Wang X, Xie W, Zhang Y, Lin P, Han L, Han P, Wang Y, Chen Z, Ji G, Zheng M, Weisleder N, Xiao RP, Takeshima H, Ma J, Cheng H. Cardioprotection of ischemia/reperfusion injury by cholesteroldependent MG53-mediated membrane repair. Circ Res 107: 76 -83, 2010.
30. Weisleder N, Takeshima H, Ma J. Mitsugumin 53 (MG53) facilitates vesicle trafficking in striated muscle to contribute to cell membrane repair. Commun Integr Biol 2: 225-226, 2009.
31. Zhai L, Dietrich A, Skurat AV, Roach PJ. Structure-function analysis of GNIP, the glycogenin-interacting protein. Arch Biochem Biophys 421: 236-242, 2004.
32. Zhu H, Lin P, De G, Choi KH, Takeshima H, Weisleder N, Ma J. Polymerase transcriptase release factor (PTRF) anchors MG53 protein to cell injury site for initiation of membrane repair. J Biol Chem 286: 12820-12824, 2011.