Protective effects of COX-2 inhibitor on titanium-particle-induced inflammatory osteolysis via the down-regulation of RANK/RANKL

Acta Biomaterialia

Volumn 7, Issue 8, 2011, Pages 3216-3221

  Geng, Dechun ^a   Mao, Haiqing ^a   Wang, Junhua ^a   Zhu, Xuesong ^a   Huang, Chen ^a   Chen, Liang ^a   Yang, Huilin ^a   Xu, Yaozeng ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

Cyclooxygenase 2; Dynastat; Osteoclastogenesis; Wear particle

Indexed keywords

ARTHROPLASTY; GENE EXPRESSION; MAMMALS; PHOSPHATASES; TISSUE; TITANIUM;

CYCLO-OXYGENASE-2 INHIBITOR; CYCLOOXYGENASE 2; DOWN-REGULATION; DYNASTAT; OSTEOCLASTOGENESIS; OSTEOLYSIS; PROTECTIVE EFFECTS; RANK/RANKL; TITANIUM PARTICLES; WEAR PARTICLES;

HISTOLOGY;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; OSTEOCLAST DIFFERENTIATION FACTOR; PARECOXIB; PROSTAGLANDIN E2; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TITANIUM; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALVARIA; CELL STRAIN 3T3; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

MURINAE; MUS;

EID: 79959850860     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2011.05.007     Document Type: Article

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