Effect of ampicillin on bleeding time in very low birth-weight neonates during the first week after birth

Journal of Perinatology

Volumn 31, Issue 7, 2011, Pages 477-480

  Sheffield, M J ^a   Lambert, D K ^a   Baer, V L ^a   Henry, E ^b   Butler, A ^c   Snow, G L ^c   Christensen, R D ^a  

^a McKay Dee Hospital Center   (United States)

^b Institute for Healthcare Delivery Research   (United States)

^c LDS HOSPITAL   (United States)

Author keywords

ampicillin; bleeding time; PFA 100; platelet function; platelet plug

Indexed keywords

AMPICILLIN;

ARTICLE; BLEEDING TIME; BLOOD CULTURE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DRUG EFFECT; DRUG WITHDRAWAL; FEMALE; GESTATIONAL AGE; HUMAN; HUMAN CELL; LONG TERM CARE; MALE; NEWBORN; PROSPECTIVE STUDY; SHORT COURSE THERAPY; SIDE EFFECT; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; VERY LOW BIRTH WEIGHT;

AMPICILLIN; ANTI-BACTERIAL AGENTS; BLEEDING TIME; BLOOD PLATELETS; COHORT STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, VERY LOW BIRTH WEIGHT; INTENSIVE CARE UNITS, NEONATAL; MALE; PROSPECTIVE STUDIES; REFERENCE VALUES; RISK ASSESSMENT; TERM BIRTH; TIME FACTORS; TREATMENT OUTCOME;

EID: 79959848270     PISSN: 07438346     EISSN: 14765543     Source Type: Journal    
DOI: 10.1038/jp.2010.154     Document Type: Article

References (22)

1. Andrew M, Castle V, Mitchell L, Paes B. Modified bleeding time in the infant. Am J Hematol 1989; 30: 190-191. (Pubitemid 19059823)
2. Borzini P, Laxxaro A, Mazzucco L, Papili F. The in-vitro bleeding time for the screening of platelet function in the newborn: assessment of a normal reference range. Eur J Pediatr 2001; 160: 199-200. (Pubitemid 32206355)
3. Del Vecchio A, Latini G, Henry E, Christensen RD. Template bleeding times of 240 neonates born at 24 to 41weeks gestation. J Perinatol 2008; 28: 427-431. (Pubitemid 351780937)
4. Del Vecchio A. Use of the bleeding time in the neonatal intensive care unit. Acta Paediatr Suppl 2002; 91: 82-86. (Pubitemid 35347065)
5. Sheffield MJ, Lambert DK, Henry E, Christensen RD. Effect of ampicillin on the bleeding time of neonatal intensive care unit patients. J Perinatol 2010; 30: 527-530.
6. Burroughs SF, Johnson GJ. Beta-lactam antibiotic-induced platelet dysfunction: evidence for irreversible inhibition of platelet activation in vitro and in vivo after prolonged exposure to penicillin. Blood 1990; 75: 1473-1480. (Pubitemid 20114887)
7. Brown III CH, Bradshaw MJ, Natelson EA, Alfrey Jr CP, Williams Jr TW. Defective platelet function following the administration of penicillin compounds. Blood 1976; 47: 949-956.
8. Burroughs SF, Johnson GJ. Beta-lactam antibiotics inhibit agonist-stimulated platelet calcium influx. Thromb Haemost 1993; 69: 503-508. (Pubitemid 23146448)
9. Sheffield MS, Schmutz N, Lambert DK, Henry E, Christensen RD. Ibuprofen lysine administration to neonates with a patent ductus arteriosus: effect on platelet plug formation assessed by in vivo and in vitro measurements. J Perinatol 2009; 29: 39-43.
10. Israels SJ, Cheang T, McMillan-Ward EM, Cheang M. Evaluation of primary hemostasis in neonates with a new in vitro platelet function analyzer. J Pediatr 2001; 138: 116-119. (Pubitemid 32097153)
11. Boudewijns M, Raes M, Peeters V, Mewis A, Cartuvvels R, Magerman K et al. Evaluation of platelet function on cord blood in 80 healthy term neonates using the Platelet Function Analyser (PFA-100); shorter in vitro bleeding times in neonates than adults. Eur J Pediatr 2003; 162: 212-213. (Pubitemid 36337695)
12. Shah U, Ma AD. Tests of platelet function. Curr Opin Hematol 2007; 14: 432-437. (Pubitemid 47457632)
13. Roschitz B, Sudi K, Köstenberger M, Muntean W. Shorter PFA-100 closure times in neonates than in adults: role of red cells, white cells, platelets and von Willebrand factor. Acta Paediatr 2001; 90: 664-670. (Pubitemid 32595871)
14. Kim IS, Jeong YH, Kang MK, Koh JS, Park Y, Hwang SJ et al. Correlation of high post-treatment platelet reactivity assessed by light transmittance aggregometry and the VerifyNow P2Y(12) assay. J Thromb Thrombolysis 2010; 30(4): 486-495.
15. Morel-Kopp MC, Aboud M, Tan CW, Kulathilake C, Ward C. Whole blood impedance aggregometry detects heparin-induced thrombocytopenia antibodies. Thromb Res 2010; 125: e234-e239.
16. Hanke AA, Dellweg C, Kienbaum P, Weber CF, Görlinger K, Rahe-Meyer N. Effects of desmopressin on platelet function under conditions of hypothermia and acidosis: an in vitro study using multiple electrode aggregometry*. Anaesthesia 2010; 65(7): 688-691.
17. Sharma P, Saxena R. A novel thromboelastographic score to identify overt disseminated intravascular coagulation resulting in a hypocoagulable state. Am J Clin Pathol 2010; 134: 97-102.
18. Bidet A, Jais C, Puymirat E, Coste P, Nurden A, Jakubowski J et al. VerifyNow and VASP phosphorylation assays give similar results for patients receiving clopidogrel, but they do not always correlate with platelet aggregation. Platelets 2010; 21: 94-100.
19. Gasparyan AY. Aspirin and clopidogrel resistance: methodological challenges and opportunities. Vasc Health Risk Manag 2010; 6: 109-112.
20. Chirico G, Barbieri F, Chirico C. Antibiotics for the newborn. J Matern Fetal Neonatal Med 2009; 22(Suppl 3): 46-49.
21. Penning-van Beest FJ, Koerselman J, Herings RM. Risk of major bleeding during concomitant use of antibiotic drugs and coumarin anticoagulants. J Thromb Haemost 2008; 6: 284-290.
22. Ferreiro JL, Sibbing D, Angiolillo DJ. Platelet function testing and risk of bleeding complications. Thromb Haemost 2010; 103: 1128-1135.