Evaluation of platelet function on cord blood in 80 healthy term neonates using the Platelet Function Analyser (PFA-100): Shorter in vitro bleeding times in neonates than adults

European Journal of Pediatrics

Volumn 162, Issue 3, 2003, Pages 212-213

  Boudewijns, Michael ^a   Raes, Marc ^a   Peeters, Veerle ^a   Mewis, Alex ^a   Cartuyvels, Reinoud ^a   Magerman, Koen ^a   Rummens, Jean Luc ^a  

^a VIRGA JESSE HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADRENALIN; COLLAGEN;

ADULT; ANALYZER; ARTICLE; BLEEDING TIME; CONTROLLED STUDY; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; NEWBORN; NEWBORN SCREENING; NORMAL VALUE; PRIORITY JOURNAL; THROMBOCYTE FUNCTION;

EID: 0347926446     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00431-002-1093-7     Document Type: Article

References (6)

1. Borzini P, Lazzaro A, Mazzucco L, Papilli F (2000) The in-vitro bleeding time for the screening of platelet function in the newborn: assessment of a normal reference range. Eur J Pediatr 160: 199-200
2. Carcao MD, Blanchette VS, Dean JA, Kern MA, Stain AM, Sparling CR, Stephens D, Ryan G, Freedman J, Rand ML (1998) The Platelet Function Analyzer (PFA-100): a novel in-vitro system for evaluation of primary haemostasis in children. Br J Haematol 101: 70-73
3. Israels SJ, Cheang T, McMillan-Ward EM, Cheang M (2001) Evaluation of primary hemostasis in neonates with a new in vitro platelet function analyzer. J Pediatr 138: 116-119
4. Kühne T, Imbach P (1998) Neonatal platelet physiology and pathophysiology. Eur J Pediatr 157: 87-94
5. Mammen EF, Comp PC, Gosselin R, Greenberg C, Hoots WK, Kessler CM, Larkin EC, Liles D, Nugent DJ (1998) PFA-100 System: a new method for assessment of platelet dysfunction. Semin Thromb Hemost 24: 195-202
6. Roschitz B, Sudi K, Köstenberger M, Muntean W (2001) Shorter PFA-100 closure times in neonates than in adults: role of red cells, white cells, platelets and von Willebrand factor. Acta Paediatr 90: 664-670