Do natural antibodies compensate for humoral immunosenescence in tropical pythons?

Functional Ecology

Volumn 25, Issue 4, 2011, Pages 813-817

  Ujvari, Beata ^a,b   Madsen, Thomas ^b,c,d  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF WOLLONGONG   (Australia)

^c LUND UNIVERSITY   (Sweden)

^d DEPARTMENT OF ZOOLOGY   (Hungary)

Author keywords

Ageing; Humoral immune response; Immunosenescence; KLH; Natural antibodies; Snake

Indexed keywords

AGING; AGING POPULATION; ANTIBODY; ANTIGEN; IMMUNE RESPONSE; IMMUNOCOMPETENCE; SENESCENCE; SNAKE; TROPICAL REGION;

LIASIS FUSCUS; PYTHONIDAE;

EID: 79959812419     PISSN: 02698463     EISSN: 13652435     Source Type: Journal    
DOI: 10.1111/j.1365-2435.2011.01860.x     Document Type: Article

References (55)

1. Arps, V., Sudowe, S. & Kölsch, E. (1998) Antigen dose-dependent difference in IgE antibody production are not due to polarization towards Th1 and Th2 cell subsets. European Journal of Immunology, 28, 681-686.
2. Attansio, R., Brasky, K.M., Robbins, S.H., Jayashankar, L., Nash, R.J. & Buttler, T.M. (2001) Age-related autoantibody production in a nonhuman primate model. Clinical and Experimental Immunology, 123, 361-365.
3. Austad, S.N. (1997) Why We Age. Wiley, New York.
4. Avrameas, S. (1991) Natural autoantibodies: from 'horror autotoxicus' to 'gnothi seauton'. Immunology Today, 12, 154-159.
5. Avrameas, S., Ternynck, T., Tsonis, I.A. & Lymberi, P. (2007) Naturally occurring B-cell autoreactivity: a critical overview. Journal of Autoimmunity, 29, 213-218.
6. Baker, N. & Ehrenstein, M.R. (2002) Cutting edge: selection of B lymphocytes subsets is regulated by natural IgM. Journal of Immunology, 169, 6686-6690.
7. Berghof, T.V.L., De Vries Reilingh, G., Nieuwland, M.G.B. & Parmentier, H.K. (2010) Effect of ageing and repeated intratracheal challenge on levels of cryptic and overt natural antibodies in poultry. Poultry Science, 89, 227-235.
8. Bergstra, T.J., Smeets, K., Nieuwland, M.G.B. & Parmentier, H.K. (2010) In vivo and vitro post translation polymorphism of chicken natural auto-antibodies. Developmental and Comparative Immunology, 34, 821-827.
9. Bruley-Rosset, M., Mouthon, L., Chanseaud, Y., Dhainaut, F., Lirochon, J. & Bourel, D. (2003) Polyreactive autoantibodies purified from human intravenous immunoglobulins prevent the development of experimental autoimmune diseases. Laboratory Investigation: Journal of Technical Methods and Pathology, 83, 1013-1023.
10. Cancro, M.P., Hao, Y., Scholz, J.L., Riley, R.L., Fracsa, D., Dunn-Walters, D.K. & Blomberg, B.B. (2009) B cells and ageing: molecules and mechanisms. Trends in Immunology, 30, 313-318.
11. Cheng, H.M. & Chamley, L. (2008) Cryptical natural autoantibodies and co-potentiators. Autoimmunity Reviews, 7, 431-434.
12. Cichon, M., Sendecka, J. & Gustavsson, L. (2003) Age-related decline in humoral immune function in collared flycatchers. Journal of Evolutionary Biology, 16, 1205-1210.
13. Cogger, H. (2000) Reptiles and Amphibians of Australia. Reed New Holland, Sydney.
14. Franceschi, C., Bonafè, M. & Velnsin, S. (2000) Human immunosenescence: the prevailing of innate immunity, the failing of clonotypic immunity, and the filling of immunological space. Vaccine, 18, 1717-1720.
15. Frasca, D., Landin, A.M., Lechner, S.C., Ryan, J.G., Schwartz, R., Riley, R.L. & Blomberg, B.B. (2008) Ageing down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig Class switch in human B cells. Journal of Immunology, 180, 5283-5290.
16. Goidl, E.A., Thorbecke, G.J., Weksler, M.E. & Siskind, G.W. (1980) Production of auto-anti-idiotypic antibody during the normal immune response: changes in the auto-anti-idiotypic antibody response and the idiotypic repertoire associated with ageing. Proceedings of the National Academy of Science of the United States of America, 77, 6788-6792.
17. Haghighi, H.R., Gong, J., Gyles, C.L., Hayes, M.A., Zhou, H., Sanei, B., Chambers, J.R. & Shariff, S. (2006) Probiotics stimulate production of natural antibodies in chickens. Clinical and Vaccine Immunology, 13, 975-980.
18. Hardy, R.R. & Hayakawa, K.A. (1994) CD5 B cells, a fetal cell linage. Advances in Immunology, 55, 297-339.
19. Hayward, A.D., Wilson, A.J., Pilkington, J.G., Pemberton, J.M. & Kruuk, L.E.B. (2009) Ageing in a variable habitat: environmental stress affects senescence in parasite resistance in St Kilda Soay sheep. Proceedings of the Royal Society of London. Series B, 276, 3477-3485.
20. Heyman, B. (2000) Regulation of antibody responses via antibodies, complement, and Fc receptors. Annual Review Immunology, 18, 709-737.
21. Hornig, R. & Lutz, H.U. (2000) Band 3 protein clustering on human erythrocytes promotes binding of naturally occurring anti-ban 3 and anti-specterin antibodies. Experimental Gerontology, 35, 1025-1044.
22. Kachamakova, N.M., Irnazarow, I., Parmentier, H.K., Savelkoul, H.F.J., Pilarczyk, A. & Wiegertjes, G.F. (2006) Genetic differences in natural antibody levels in common carp (Cyprinus carpio L.). Fish & Shellfish Immunology, 21, 404-413.
23. Kantor, A.B. & Herzenberg, L.A. (1993) Origin of murine B cells lineages. Annual Review Immunology, 11, 501-538.
24. Kirkwood, T.B.L. & Austad, S.N. (2000) Why do we age?. Nature, 408, 233-238.
25. Krishnaraj, R. (1992) Immunosenescence of human NK cells: effects on tumor target recognition, lethal hit and interferon sensitivity. Immunology Letters, 34, 79-84.
26. Lanzavecchia, A. & Sallusto, F. (2007) Toll-like receptors and innate immunity in B-cell activation of antibody responses. Current Opinion in Immunology, 9, 268-274.
27. LeMaoult, J., Szabo, P. & Weksler, M.E. (1997) Effect of age on humoral immunity, selection of the B-cell repertoire and B-cell development. Immunological Reviews, 160, 115-126.
28. Ligthart, G.J., Schuit, H.R.E. & Hijmans, W. (1989) Natural killer cell function is not diminished in the healthy aged and is proportional to the number of NK cells in the peripheral blood. Immunology, 68, 396-402.
29. Lutz, H.U. (2007) Homeostatic roles of naturally occurring antibodies: an overview. Journal of Autoimmunity, 29, 287-294.
30. Lutz, H.U., Binder, C.J. & Kaveri, S.V. (2009) Natural occurring auto-antibodies in homeostasis and disease. Trends in Immunology, 30, 43-51.
31. Madsen, T. & Shine, R. (2000) Silver spoons and snake sizes: prey availability early in life influences long-term growth rates of free-ranging pythons. Journal of Animal Ecology, 69, 952-958.
32. Madsen, T., Ujvari, B., Nandakumar, K.S., Hasselquist, D. & Holmdahl, R. (2007) Do "infectious" prey select for high levels of natural antibodies in tropical pythons? Evolutionary Ecology, 21, 271-279.
33. Miller, R.A. (1996) The ageing immune system: primer and prospectus. Science, 273, 70-74.
34. Møller, A.P. & Haussy, C. (2007) Fitness consequences of variation in natural antibodies and complement in the Barn Swallow Hirundo rustica. Functional Ecology, 21, 363-371.
35. Nobrega, A., Haury, M., Gueret, R., Coutinho, A. & Weksler, M.E. (1996) The age-associated increase in autoreactive immunoglobulins reflects a quantitative increase in specificities detectable at lower concentration in young mice. Scandinavian Journal of Immunology, 44, 437-443.
36. Notkins, A.B. (2004) Polyreactivity of antibody molecules. Trends in Immunology, 25, 174-179.
37. Ochsenbein, A.F. & Zinkernagel, R.M. (2000) Natural antibodies and complement link innate and acquired immunity. Immunology Today, 21, 624-630.
38. Ochsenbein, A.F., Fehr, T., Lutz, C., Suter, M., Brombacher, F., Hengartner, H. & Zinkernagel, R.M. (1999) Control of early viral and bacterial distribution and disease by natural antibodies. Science, 286, 2156-2159.
39. Palacio, M.G., Cunnick, J.E., Winkler, D.W. & Vleck, C.M. (2007) Immunosenescence in some but not all immune components in a free-living vertebrate, the tree swallow. Proceeding of the Royal Society B, 274, 951-957.
40. Parmentier, H.K., De Vries Reilingh, G. & Lammers, A. (2008) Decreased specific antibody responses to α-Gal-conjugated antigen in animals with preexisting high levels of natural antibodies binding α-Gal residues. Poultry Science, 87, 918-926.
41. Parmentier, H.K., Lammers, A., Hoekman, J.J., De Vries Reilingh, G., Zaanen, I.T.A. & Savelkoul, H.F.J. (2004) Different levels of natural antibodies in chickens divergently selected for specific antibody response. Developmental and Comparative Immunology, 28, 39-49.
42. Pawelec, G., Larbi, A. & Derhovanessian, E. (2010) Senescence of the human immune system. Journal of Comparative Pathology, 142, S39-S44.
43. Pelletier, F., Page, K.A., Ostiguy, T. & Festa-Bianchet, M. (2005) Fecal counts of lungworm larvae and reproductive effort in bighorn sheep, Ovis canadensis. Oikos, 110, 473-480.
44. Peng, Y., Kowalewski, R., Kim, S. & Elkon, K.B. (2005) The role of IgM antibodies in the recognition and clearance of apoptotic cells. Molecular Immunology, 42, 781-787.
45. Prokesova, L., Tuckova, L., Cukrowska, B., Tlaskalova-Hogenova, H. & Barot-Ciobaru, R. (1996) Occurence and specificity of human natural and in vitro induced antibodies to Nocardia opaca anigens. International Journal of Immunopharmacology, 18, 661-668.
46. Saino, N., Ferrari, R.P., Romano, M., Rubolini, D. & Møller, A.P. (2003) Humoral immune response in relation to senescence, sex and sexual ornamentation in the barn swallow (Hirundo rustica). Journal of Evolutionary Biology, 16, 1127-1134.
47. Schwanz, L., Warner, D.A., McGaugh, S., Di Terlizzi, R. & Bronikowski, A. (2011) State-dependent physiological maintenance in a long-lived ectotherm, the painted turtle (Chrysemys picta). Journal of Experimental Biology, 214, 88-97.
48. Shanley, D.P., Aw, D., Nancy, R., Manley, N.R. & Palmer, D.B. (2009) An evolutionary perspective on the mechanisms of immunosenescence. Trends in Immunology, 30, 374-381.
49. Sinyakov, M.S. & Avtalion, R.R. (2009) Vaccines and natural antibodies: a link to be considered. Vaccine, 27, 1985-1986.
50. Star, L., Frankena, K., Kemp, B., Nieuwland, M.G.B. & Parmentier, H.K. (2007) Innate immune competence and survival in pure bred layer lines. Poultry Science, 86, 1090-1099.
51. Tonegawa, S. (1983) Somatic generation of somatic antibody diversity. Nature, 302, 575-581.
52. Ujvari, B. & Madsen, T. (2006) Age, parasites and condition affect humoral immune response in tropical pythons. Behavioral Ecology, 17, 20-24.
53. Weklser, M.E. (2000) Changes in the B-cell repertoire with age. Vaccine, 18, 1624-1628.
54. Zharahary, D., Segev, Y. & Gershon, H. (1977) The affinity and spectrum of cross reactivity of antibody production in senescent mice: the IgM response. Mechanisms of Ageing and Development, 6, 385-392.
55. - phenotypes. Clinical and Experimental Immunology, 137, 88-100.