Correlation between E-cadherin and CD44 adhesion molecules expression and cervical lymph node metastasis in oral tongue SCC: Predictive significance or not

Pathology Research and Practice

Volumn 207, Issue 7, 2011, Pages 448-451

  Mostaan, Leila Vazifeh ^a   Khorsandi, Mohammad Taghi ^b   Sharifian, Shahriar Mohammad Reza ^a   Shandiz, Fatemeh Homee ^a   Mirashrafi, Fatemeh ^b   Sabzari, Homa ^a   Badiee, Reza ^a   Borghei, Hasti ^b   Yazdani, Nasrin ^b  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

CD44; E cadherin; Lymph node metastasis; Squamous cell carcinoma; Tongue

Indexed keywords

CELL ADHESION MOLECULE; HERMES ANTIGEN; UVOMORULIN;

ADULT; AGED; ARTICLE; CANCER STAGING; CELL ACTIVITY; CELL FUNCTION; CERVICAL LYMPH NODE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SQUAMOUS CELL CARCINOMA; TONGUE CARCINOMA; TUMOR BIOPSY; TUMOR DIFFERENTIATION;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD44; CADHERINS; CARCINOMA, SQUAMOUS CELL; FEMALE; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MOUTH NEOPLASMS; NECK; NEOPLASM INVASIVENESS; PREDICTIVE VALUE OF TESTS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 79959742573     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2011.04.001     Document Type: Article

References (27)

1. Freitas M.D., Caballero T.G., Lopez J.A., et al. Reduced E-cadherin expression is an indicator of unfavourable prognosis in oral squamous cell carcinoma. Oral Oncol. 2006, 42:190-200.
2. González-Moles M.A., Bravo M., Ruiz-Ávila I., Esteban F., Bascones-Martínez A., González-Moles S. Adhesion molecule CD44 expression in non-tumour epithelium adjacent to tongue cancer. Oral Oncol. 2004, 40:281-286.
3. Guttman D., Stern Y., Shpitzer T., et al. Expression of MMP-1, TIMP-1, CD34 and factor-8 as prognostic markers for squamous cell carcinoma of the tongue. Oral Oncol. 2004, 40:798-803.
4. Hagen B.E.K., Simon J.R. Comparative study of the expression of p53, Ki67, E-cadherin and MMP-1 in verrucous hyperplasia and verrucous carcinoma of the oral cavity. Head Neck Pathol. 2007, 1:118-122.
5. Hannen E.J.M., Van der Laak J., Manni J., et al. Improved prediction of metastasis in tongue carcinoma, combining vascular and nuclear tumor parameters. Cancer 2001, 92:1881-1887.
6. Jarvinen A., Autio R., Kilpinen S. High-resolution copy number and gene expression microarray analyses of head and neck squamous cell carcinoma cell lines of tongue and larynx. Genes. Chromosomes Cancer 2008, 500-509.
7. Kosunen A., Pirinen R., Ropponen K., Pukkila M., Kellokoski J., Virtaniemi J., Sironen R., Juhola M., Kumpulainen E., Johansson R., Nuutinen J., Kosma V.-M. CD44 expression and its relationship with MMP-9, clinicopathological factors and survival in oral squamous cell carcinoma. Oral Oncol. 2007, 43:51-59.
8. Mattijssen V., Peters H.M., Schalkwijk l, et al. E-cadherin expression in head and neck squamous-cell carcinoma is associated with clinical outcome. Int. J. Cancer 1993, 4:580-585.
9. Sh. Nakayama, A. Sasaki, H. Mese, et al., Establishment of high and low metastasis cell lines derived from a human tongue squamous cell carcinoma, Invasion Metast. 18 (1998/1999) 219-228.
10. Okamoto M., Nishimine M., Kishi M., et al. prediction of delayed neck metastasis in patients with stage I/II squamous cell carcinoma of the tongue. J. Oral Pathol. Med. 2002, 31:227-233.
11. Olsen S.M., Moore E.J., Koch C.A., Kasperbauer J.L., Olsen K.D. Oral cavity and oropharynx squamous cell carcinoma with metastasis to the parotid lymph nodes. Oral Oncol. 2011, 47:142-144.
12. Kudo Y., Kitajiama Sh., Ogawa I., et al. Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous β-catenin. Clin. Cancer Res. 2004, 10:54-55.
13. Kurtz K.A., Hoffman H.T., Zimmerman M.B., et al. Decreased E-cadherin but not beta-catenin expression is associated with vascular invasion and decreased survival in head and neck squamous carcinomas. Otolaryngol. Head Neck Surg. 2006, 1:142-146.
14. Lyons A.J., Jones J. Cell adhesion molecules, the extracellular matrix and oral squamous carcinoma. Int. J. Oral Maxillofac. Surg. 2007, 36:671-679.
15. Massano J., Regateiro F., Januano G. Oral squamous cell carcinoma: review of prognostic and predictive factors. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2006, 102:67-76.
16. Dalchau R., Kirkley J., Fabre J.W. Monoclonal antibody to a human leukocyte-specific membrane glycoprotein probably homologous to the leukocyte-common (L-C) antigen of the rat. Eur. J. Immunol. 1980, 10:737-744.
17. Sato S., Miyauchi M., Takekoshi T., et al. Reduced expression of CD44 variant 9 is related to lymph node metastasis and poor survival in squamous cell carcinoma of tongue. Oral Oncol. 2000, 36:545-549.
18. Takamune Y., Ikebe T., Nagano O., Nakayama H., Ota K., Obayashi T., Saya H., Shinohara M. ADAM-17 associated with CD44 cleavage and metastasis in oral squamous cell carcinoma. Virchows Arch. 2007, 450:169-177.
19. Pyo S.W., Hashimoto M., Kim Y.S., et al. Expression of E-cadherin, P-cadherin and N-cadherin in oral squamous cell carcinoma: correlation with clinicopathologic features and patients outcome. J. Cranio. Maxillofac. Surg. 2007, 35:1-9.
20. Sakaki T., Tamura I., Kadota H., Kakudo K. Changing expression of E- and P-cadherin during rat tongue carcinogenesis induced by 4-nitroquinoline1-oxide. J. Oral Pathol. Med. 2003, 32:530-537.
21. Siebers T.J.H., Merkx M.A.W., Slootweg P.J., et al. No high-risk HPV detected in SCC of the oral tongue in the absolute absence of tobacco and alcohol - a case study of seven patients. Oral Maxillofac. Surg. 2008, 12:185-188.
22. Stoll C., Baretton G., Soost F. Prognostic importance of the expression of CD44 splice variants in oral squamous cell carcinoma. Oral Oncol. 1999, 35:484-489.
23. Syrjanen S. Human papillomavirus (HPV) in head and neck cancer. J. Clin. Virol. 2005, 32S:59-61.
24. Tracey A.M., Harrison G., Mansel R.E. The role of the CD44/ezrin complex in cancer metastasis. Crit. Rev. Oncol./Hematol. 2003, 46:165-186.
25. Tsantoulis P.K., Kastrinakis N.G., Tourvas A.D., et al. Advances in the biology of oral cancer. Oral Oncol. 2007, 43:523-534.
26. Veness M.J. Tongue cancer in younger patients. Austr. Radiol. 1999, 43:76-81.
27. Wang X., Zhang J., Fan M., et al. The expression of E-cadherin at the invasive tumor front of oral squamous cell carcinoma: immunohistochemical and RT-PCR analysis with clinicopathological correlation. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2009, 107:547-554.