Improved prediction of metastasis in tongue carcinomas, combining vascular and nuclear tumor parameters

Cancer

Volumn 92, Issue 7, 2001, Pages 1881-1887

  Hannen, Egied J M ^a,b   Van Der Laak, Jeroen A W M ^a   Manni, Johannes J ^b   Pahlplatz, Martin M M ^a   Freihofer, Hans Peter M ^a   Slootweg, Piet J ^c   Koole, Ronald ^c   De Wilde, Peter C M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Cell nucleus; Cell nucleus chromatin; Head and neck neoplasms; Logistic model; Neoplasm metastasis; Neoplasm staging; Neovascularization pathologic; Radical neck dissection; Tongue neoplasms

Indexed keywords

ANGIOGENESIS; ARTICLE; CHROMATIN CONDENSATION; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; METASTASIS; PREDICTION; PREVALENCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TONGUE CARCINOMA; TUMOR VOLUME; VASCULAR TUMOR;

CARCINOMA, SQUAMOUS CELL; CELL NUCLEUS; CHROMATIN; HUMANS; LOGISTIC MODELS; NEOPLASM METASTASIS; NEOVASCULARIZATION, PATHOLOGIC; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; TONGUE NEOPLASMS;

EID: 0035476277     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0142(20011001)92:7<1881::AID-CNCR1705>3.0.CO;2-M     Document Type: Article

References (57)

1. Critical determinants of cancer metastasis: Rationale for therapy
2. Prognosis in mouth cancer: Tumour factors
3. Proposal for modification of the TNM staging classification for cancer of the oral cavity
4. Analysis of prognostic factors in squamous cell carcinomas of the head and neck
5. Development of a new staging system for recurrent oral cavity and oropharyngeal squamous cell carcinoma
6. Prognostic significance of DNA ploidy in oral squamous cell carcinomas, A retrospective flow and image cytometric study with comparison of DNA ploidy in excisional biopsy specimens and resection specimens, primary, tumors, and lymph node metastases
7. Flow cytometric analysis of nuclear DNA content in tongue squamous cell carcinoma: Relation to cervical lymph node metastasis
8. The prognostic value of individual histologic grading parameters in small lingual squamous cell carcinomas. The importance of the pattern of invasion
9. Prediction of cervical lymph node metastasis in squamous cell carcinoma of the tongue/floor of mouth
10. Low p27 expression correlates with poor prognosis for patients with oral tongue squamous cell carcinoma
11. The prognostic value of spontaneous apoptosis, Bax, Bcl-2, and p53 in oral squamous cell carcinoma of the tongue
12. Distinct patterns of chromosomal alterations in high and low grade head and neck squamous cell carcinomas
13. Allelic loss at chromosomes 3p, 8p, 13q, and 17p associated with poor prognosis in head and neck cancer
14. Molecular genetics of head and neck cancer
15. Comparison of oral squamous cell carcinoma in younger and older patients in India
16. Prevalence of Epstein-Barr virus in oral squamous cell carcinoma
17. Tumor thickness predicts cervical metastasis in patients with stage I/II carcinoma of the tongue
18. Depth of invasion as a predictive factor for cervical lymph node metastasis in tongue carcinoma
19. Pattern of invasion and margin assessment in patients with oral tongue cancer
20. E-cadherin expression in head and neck squamous-cell carcinoma is associated with clinical outcome
21. The biology of tumor invasion, angiogenesis and lymph node metastasis
22. Molecular biology of cancer: Invasion and metastasis
23. Nuclear morphometry in squamous cell carcinoma (SCC) of the tongue
24. Mean nuclear area and chromosomal DNA content of squamous cell carcinomas of the oral cavity using computerized image analysis
25. An image analysis study on nuclear morphology in metastasized and non-metastasized squamous cell carcinomas of the tongue
26. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
27. The hallmarks of cancer
28. Tumoural vascularity as a prognostic factor in cancer patients: The evidence continues to grow
29. Improved survival for patients with clinically T1/T2, NO tongue tumors undergoing a prophylactic neck dissection
30. Supraomohyoid neck dissection with frozen section biopsy as a staging procedure in the clinically node-negative neck in carcinoma of the oral cavity
31. T1 and T2 squamous cell carcinoma of the oral tongue: Prognostic factors and the role of elective lymph node dissection
32. Frequency and therapeutic implications of "skip metastases" in the neck from squamous carcinoma of the oral tongue
33. Pitfalls in the treatment of delayed lymph-node metastases after control of small tongue carcinomas
34. Development of distant metastasis after treatment of advanced-stage head and neck cancer
35. Classification of neck dissection: Current concepts and future considerations
36. Quantification of tumour vascularity in squamous cell carcinoma of the head and neck using CARD amplification, a systematic sampling technique, and true colour image analysis
37. Hue-saturation-density (HSD) model for stain recognition in digital images from transmitted light microscopy
38. Characterization of chromatin distribution in cell nuclei
39. Chromatin texture measurement by Markovian analysis. Use of nuclear models to define and select texture features
40. Markovian analysis of cervical cell images
41. Texture analysis using gray level run lengths
42. Pathology of the NO neck
43. Management of the neck for squamous cell carcinoma
44. Predictive value of a single diagnostic test in unselected populations
45. Causes of oral tongue cancer treatment failures. Analysis of autopsy cases
46. The value of ultrasound with ultrasound-guided fine-needle aspiration biopsy compared to computed tomography in the detection of regional metastases in the clinically negative neck
47. Cancer metastasis
48. Supramolecular ordering of DNA in the cholesteric liquid crystalline phase: An ultrastructural study
49. The relationship of quantitative nuclear morphology to molecular genetic alterations in the adenoma-carcinoma sequence of the large bowel
50. Computer-assisted chromatin texture characterization of Feulgen-stained nuclei in a series of 331 transitional bladder cell carcinomas
51. DNA-cytometry of progressive and regressive cervical intraepithelial neoplasia
52. Tumor angiogenesis as a prognostic assay for invasive ductal breast carcinoma
53. Neoangiogenesis and squamous cell carcinoma of the tongue
54. Heterogeneity and reproducibility of microvessel counts in breast cancer
55. Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck
56. Evolving role of modifications in neck dissection for oral squamous carcinoma