ErbB2-associated changes in the lysosomal proteome

Proteomics

Volumn 11, Issue 14, 2011, Pages 2830-2838

  Nylandsted, Jesper ^a   Becker, Andrea C ^b   Bunkenborg, Jakob ^c   Andersen, Jens S ^c   Dengjel, Jörn ^b   Jäättelä, Marja ^a  

^a DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Cancer; Cell biology; ErbB2 oncogene; Immunoprecipitation; Lysosome; SILAC mass spectrometry

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; CATHEPSIN; CATHEPSIN D; CD63 ANTIGEN; CD9 ANTIGEN; CHARGED MULTIVESICULAR BODY PROTEIN 3; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FERRITIN; FLOTILLIN 1; FLOTILLIN 2; GAMMA GLUTAMYL HYDROLASE; GLUCOSYLCERAMIDASE; MYOFERLIN; MYOSIN; MYOSIN IB; MYOSIN ID; N ACETYL BETA GLUCOSAMINIDASE; NICASTRIN; PLAKOPHILIN 4; PROTEIN; PUTATIVE PHOSPHOLIPASE B LIKE 1; RAS RELATED PROTEIN RAB 22A; SYNTAXIN 12; SYNTAXIN 8; TRANSFERRIN RECEPTOR PROTEIN 1; TRANSMEMBRANE PROTEIN 192; TROPOMODULIN 3; UNCLASSIFIED DRUG; VESICLE ASSOCIATED MEMBRANE PROTEIN 7; VESICLE ASSOCIATED MEMBRANE PROTEIN 8; VESICLE TRANSPORT THROUGH INTERACTION WITH T SNARES HOMOLOH 1B;

ARTICLE; BREAST CARCINOMA; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; LYSOSOME; LYSOSOME MEMBRANE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS;

CELL LINE, TUMOR; HUMANS; IMMUNOMAGNETIC SEPARATION; INTRACELLULAR MEMBRANES; LYSOSOMES; PROTEOME; PROTEOMICS; RECEPTOR, ERBB-2; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 79959742220     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201000734     Document Type: Article

References (39)

1. Luzio, J. P., Pryor, P. R., Bright, N. A., Lysosomes: fusion and function. Nat. Rev. Mol. Cell Biol. 2007, 8, 622-632.
2. Saftig, P., Klumperman, J., Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat. Rev. Mol. Cell Biol. 2009, 10, 623-635.
3. Kirkegaard, T., Jaattela, M., Lysosomal involvement in cell death and cancer. Biochim. Biophys. Acta 2009, 1793, 746-754.
4. Groth-Pedersen, L., Jaattela, M., Combating apoptosis and multidrug resistant cancers by targeting lysosomes. Cancer Lett. 2010 [Epub ahead of print].
5. Braulke, T., Bonifacino, J. S., Sorting of lysosomal proteins. Biochim. Biophys. Acta 2009, 1793, 605-614.
6. Pryor, P. R., Luzio, J. P., Delivery of endocytosed membrane proteins to the lysosome. Biochim. Biophys. Acta 2009, 1793, 615-624.
7. Hernandez, A., Serrano, G., Herrera-Palau, R., Perez-Castineira, J. R., Serrano, A., Intraorganellar acidification by V-ATPases: a target in cell proliferation and cancer therapy. Recent Pat. Anticancer Drug Discov. 2010, 5, 88-98.
8. Beyenbach, K. W., Wieczorek, H., The V-type H+ ATPase: molecular structure and function, physiological roles and regulation. J. Exp. Biol. 2006, 209, 577-589.
9. Vellodi, A., Lysosomal storage disorders. Br. J. Haematol. 2005, 128, 413-431.
10. Ballabio, A., Gieselmann, V., Lysosomal disorders: from storage to cellular damage. Biochim. Biophys. Acta 2009, 1793, 684-696.
11. Joyce, J. A., Baruch, A., Chehade, K., Meyer-Morse, N. et al., Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis. Cancer Cell 2004, 5, 443-453.
12. Fehrenbacher, N., Jaattela, M., Lysosomes as targets for cancer therapy. Cancer Res. 2005, 65, 2993-2995.
13. Mohamed, M. M., Sloane, B. F., Cysteine cathepsins: multifunctional enzymes in cancer. Nat. Rev. Cancer 2006, 6, 764-775.
14. Zimmermann, A. C., Zarei, M., Eiselein, S., Dengjel, J., Quantitative proteomics for the analysis of spatio-temporal protein dynamics during autophagy. Autophagy 2010, 6, 1009-1016.
15. Muller, M., Baudhuin, P., de, D. C., Lysosomes in Tetrahymena pyriformis. I. Some properties and lysosomal localization of acid hydrolases. J. Cell Physiol. 1966, 68, 165-175.
16. Fehrenbacher, N., Bastholm, L., Kirkegaard-Sorensen, T., Rafn, B. et al., Sensitization to the lysosomal cell death pathway by oncogene-induced down-regulation of lysosome-associated membrane proteins 1 and 2. Cancer Res. 2008, 68, 6623-6633.
17. Diettrich, O., Mills, K., Johnson, A. W., Hasilik, A., Winchester, B. G., Application of magnetic chromatography to the isolation of lysosomes from fibroblasts of patients with lysosomal storage disorders. FEBS Lett. 1998, 441, 369-372.
18. Nishi, T., Forgac, M., The vacuolar (H+)-ATPases - nature's most versatile proton pumps. Nat. Rev. Mol. Cell Biol. 2002, 3, 94-103.
19. Egeblad, M., Mortensen, O. H., Jaattela, M., Truncated ErbB2 receptor enhances ErbB1 signaling and induces reversible, ERK-independent loss of epithelial morphology. Int. J. Cancer 2001, 94, 185-191.
20. Nylandsted, J., Gyrd-Hansen, M., Danielewicz, A., Fehrenbacher, N. et al., Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization. J. Exp. Med. 2004, 200, 425-435.
21. Cox, J., Mann, M., MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat. Biotechnol. 2008, 26, 1367-1372.
22. Storey, J. D., Tibshirani, R., Statistical significance for genomewide studies. Proc. Natl. Acad. Sci. USA 2003, 100, 9440-9445.
23. Ong, S. E., Mann, M., A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC). Nat. Protoc. 2006, 1, 2650-2660.
24. Dengjel, J., Kratchmarova, I., Blagoev, B., Mapping protein-protein interactions by quantitative proteomics. Methods Mol. Biol. 2010, 658, 267-278.
25. Schroder, B., Wrocklage, C., Pan, C., Jager, R. et al., Integral and associated lysosomal membrane proteins. Traffic 2007, 8, 1676-1686.
26. Lubke, T., Lobel, P., Sleat, D. E., Proteomics of the lysosome. Biochim. Biophys. Acta 2009, 1793, 625-635.
27. Casey, T. M., Meade, J. L., Hewitt, E. W., Organelle proteomics: identification of the exocytic machinery associated with the natural killer cell secretory lysosome. Mol. Cell. Proteomics 2007, 6, 767-780.
28. Schroder, B. A., Wrocklage, C., Hasilik, A., Saftig, P., The proteome of lysosomes. Proteomics 2010, 10, 4053-4076.
29. Lata, S., Schoehn, G., Solomons, J., Pires, R. et al., Structure and function of ESCRT-III. Biochem. Soc. Trans. 2009, 37, 156-160.
30. Kashiwaya, K., Hosokawa, M., Eguchi, H., Ohigashi, H. et al., Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis. Cancer Sci. 2009, 100, 457-464.
31. Boonen, M., Hamer, I., Boussac, M., Delsaute, A. F. et al., Intracellular localization of p40, a protein identified in a preparation of lysosomal membranes. Biochem. J. 2006, 395, 39-47.
32. Boonen, M., Rezende de, C. R., Cuvelier, G., Hamer, I., Jadot, M., A dileucine signal situated in the C-terminal tail of the lysosomal membrane protein p40 is responsible for its targeting to lysosomes. Biochem. J. 2008, 414, 431-440.
33. Margalit, A., Brachner, A., Gotzmann, J., Foisner, R., Gruenbaum, Y., Barrier-to-autointegration factor - a BAFfling little protein. Trends Cell Biol. 2007, 17, 202-208.
34. Haraguchi, T., Koujin, T., Osakada, H., Kojidani, T. et al., Nuclear localization of barrier-to-autointegration factor is correlated with progression of S phase in human cells. J. Cell Sci. 2007, 120, 1967-1977.
35. Ross, J. S., Fletcher, J. A., The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Oncologist 1998, 3, 237-252.
36. Cardoso, C. M., Groth-Pedersen, L., Hoyer-Hansen, M., Kirkegaard, T. et al., Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells. PLoS One 2009, 4, e4424.
37. Shankar, J., Messenberg, A., Chan, J., Underhill, T. M. et al., Pseudopodial actin dynamics control epithelial-mesenchymal transition in metastatic cancer cells. Cancer Res. 2010, 70, 3780-3790.
38. Radford, K. J., Mallesch, J., Hersey, P., Suppression of human melanoma cell growth and metastasis by the melanoma-associated antigen CD63 (ME491). Int. J. Cancer 1995, 62, 631-635.
39. Lawson, D. M., Artymiuk, P. J., Yewdall, S. J., Smith, J. M. et al., Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts. Nature 1991, 349, 541-544.