Brain arteriovenous malformations: From diagnosis to treatment

Journal of Neurosurgical Sciences

Volumn 55, Issue 1, 2011, Pages 39-56

  Buis, D R ^a   Van Den Berg, R ^b   Lagerwaard, F J ^a   Vandertop, W P ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Cardiovascular diseases; Intracranial arteriovenous malformations; Nervous system diseases; Neurosurgery; Vascular malformations

Indexed keywords

DOXYCYCLINE; MINOCYCLINE; PYRROLIDINE DITHIOCARBAMATE;

BRAIN ARTERIOVENOUS MALFORMATION; BRAIN HEMORRHAGE; CLINICAL FEATURE; ENDOVASCULAR SURGERY; FOLLOW UP; HUMAN; NEUROIMAGING; NEUROSURGERY; NONHUMAN; PRACTICE GUIDELINE; PREGNANCY; PREVALENCE; RADIATION DOSE FRACTIONATION; REVIEW; RISK ASSESSMENT; SEIZURE; STEREOTACTIC RADIOSURGERY; TREATMENT PLANNING;

HUMANS; INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; NEUROSURGICAL PROCEDURES; RADIOSURGERY; RISK FACTORS;

EID: 79959741860     PISSN: 00264881     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (234)

1. Tanaka R, Miyasaka Y, Fujii K, Kan S, Yagishita S. Vascular structure of arteriovenous malformations. J Clin Neurosci 2000;7:24-8.
2. Kim H, Marchuk DA, Pawlikowska L, Chen Y, Su H, Yang GY et al. Genetic considerations relevant to intracranial hemorrhage and brain arteriovenous malformations. Acta Neurochir Suppl 2008;105:199-206.
3. Mahmoud M, Allinson KR, Zhai Z, Oakenfull R, Ghandi P, Adams RH et al. Pathogenesis of arteriovenous malformations in the absence of endoglin. Circ Res 2010;106:1425-33.
4. Spetzler RF, Martin NA. A proposed grading system for arteriovenous malformations. J Neurosurg 1986;65:476-83. (Pubitemid 16000693)
5. Mullan S, Mojtahedi S, Johnson DL, Macdonald RL. Embryological basis of some aspects of cerebral vascular fistulas and malformations. J Neurosurg 1996;85:1-8. (Pubitemid 26195030)
6. Lasjaunias P. A revised concept of the congenital nature of cerebral arteriovenous malformations. Interv Neuroradiol 1997;3:275-81. (Pubitemid 28066991)
7. Bhattacharya JJ, Luo CB, Suh DC, Alvarez H, Rodesch G, Lasjaunias PL. Wyburn-Mason or Bonnet-Dechaume-Blanc as cerebrofacial arteriovenous metameric syndromes (CAMS): a new concept and a new classification. Interv Neuroradiol 2001;7:5-17.
8. Krings T, Ozanne A, Chng SM, Alvarez H, Rodesch G, Lasjaunias PL. Neurovascular phenotypes in hereditary haemorrhagic telangiectasia patients according to age. Review of 50 consecutive patients aged 1 day-60 years. Neuroradiology 2005;47:711-20. (Pubitemid 41554551)
9. van Beijnum J, van der Worp HB, Schippers HM, van Nieuwenhuizen O, Rappelle LJ, Rinkel GJ et al. Familial occurrence of brain arteriovenous malformations: a systematic review. J Neurol Neurosurg Psychiatry 2007;78:1213-7.
10. Pawlikowska L, Tran MN, Achrol AS, Ha C, Burchard E, Choudhry S et al. Polymorphisms in transforming growth factor-beta-related genes ALK1 and ENG are associated with sporadic brain arteriovenous malformations. Stroke 2005;36:2278-80.
11. Mahajan A, Manchandia T, Gould G, Bulsara K. De novo arteriovenous malformations, case report and review of the literature. Neurosurg Rev 2010;33:115-9.
12. Du R, Hashimoto T, Tihan T, Young WL, Perry V, Lawton MT. Growth and regression of arteriovenous malformations in a patient with hereditary hemorrhagic telangiectasia. Case report. J Neurosurg 2007;106:470-7. (Pubitemid 46354302)
13. Minakawa T, Tanaka R, Koike T, Takeuchi S, Sasaki O. Angiographic follow-up study of cerebral arteriovenous malformations with reference to their enlargement and regression. Neurosurgery 1989;24:68-74.
14. Kim H, Pawlikowska L, Chen Y, Su H, Yang GY, Young WL. Brain arteriovenous malformation biology relevant to hemorrhage and implication for therapeutic development. Stroke 2009:40(3 Suppl):S95-S97.
15. Park SO, Wankhede M, Lee YJ, Choi EJ, Fliess N, Choe SW et al. Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia. J Clin Invest 2009;119:3487-96.
16. Geibprasert S, Pongpech S, Jiarakongmun P, Shroff MM, Armstrong DC, Krings T. Radiologic Assessment of Brain Arteriovenous Malformations: What Clinicians Need to Knowl. Radiographics 2010;30:483-501.
17. Bruner JM, Tien RD, McLendon RE. Tumors of vascular origin. In: Bigner DD, McLendon RE, Bruner JM, editors. Russell & Rubinstein's pathology of tumors of the nervous system. 6th ed. London: Arnold; 1998 p. 239-93.
18. Gault J, Sarin H, Awadallah NA, Shenkar R, Awad IA. Pathobiology of human cerebrovascular malformations: basic mechanisms and clinical relevance. Neurosurgery 2004;55:1-16. (Pubitemid 38859066)
19. Isoda K, Fukuda H, Takamura N, Hamamoto Y. Arteriovenous malformation of the brain -histological study and micrometric measurement of abnormal vessels. Acta Pathol Jpn 1981;31:883-93.
20. Berenstein A, Lasjaunias P, TerBrugge KG. Cerebral vascular malformations: incidence, classification, angioarchitecture, and symptomatology of brain arteriovenous and venous malformations. In: Berenstein A, Lasjaunias P, TerBrugge KG, editors. Surgical Neuroangiography 2.2 Clinical and endovascular treatment aspect in adults. 2nd edition. Berlin: Springer Verlag; 2004. p. 609-94.
21. Brocheriou I, Capron F Malformations artérioveineuses intracrâniennes: aspects anatomo-pathologiques. J Neuroradiol 2004;31:359-61. (Pubitemid 39665175)
22. Matsubara S, Bourdeau A, TerBrugge KG, Wallace C, Letarte M. Analysis of endoglin expression in normal brain tissue and in cerebral arteriovenous malformations. Stroke 2000;31:2653-60.
23. Mandybur TI, Nazek M. Cerebral arteriovenous malformations. A detailed morphological and immunohistochemical study using actin. Arch Pathol Lab Med 1990;114:970-3.
24. WongJH, Awad IA, Kim JH. Ultrastructural pathological features of cerebrovascular malformations: a preliminary report. Neurosurgery 2000;46:1454-9. (Pubitemid 32037675)
25. Stapf C, Mast H, Sciacca RR, Berenstein A, Nelson PK, Gobin YP et al. The New York Islands AVM Study: design, study progress, and initial results. Stroke 2003;34:e29-e33.
26. Al-Shahi R, Bhattacharya JJ, Currie DG, Papanastassiou V, Ritchie V, Roberts RC et al. Prospective, population-based detection of intracranial vascular malformations in adults: the Scottish Intracranial Vascular Malformation Study (SIVMS). Stroke 2003;34:1163-9.
27. Hillman J. Population-based analysis of arteriovenous malformation treatment. J Neurosurg 2001;95:633-7. (Pubitemid 33031425)
28. Jessurun GA, Kamphuis DJ, van der Zande FH, Nossent JC. Cerebral arteriovenous malformations in The Netherlands Antilles. High prevalence of hereditary hemorrhagic telangiectasia-related single and multiple cerebral arteriovenous malformations. Clin Neurol Neurosurg 1993;95:193-8.
29. Gabriel RA, Kim H, Sidney S, McCulloch CE, Singh V, Johnston SC et al. Ten-year detection rate of brain arteriovenous malformations in a large, multiethnic, defined population. Stroke 2010;41:21-6.
30. Al-Shahi R, Fang JS, Lewis SC, Warlow CP. Prevalence of adults with brain arteriovenous malformations: a community based study in Scotland using capture-recapture analysis. J Neurol Neurosurg Psychiatry 2002;73:547-51. (Pubitemid 35246809)
31. Weber F, Knopf H. Incidental findings in magnetic resonance imaging of the brains of healthy young men. J Neurol Sci 2006;240:81-4. (Pubitemid 41814958)
32. Fults D, Kelly DL, Jr. Natural history of arteriovenous malformations of the brain: a clinical study. Neurosurgery 1984;15:658-62.
33. Hofmeister C, Stapf C, Hartmann A, Sciacca RR, Mansmann U, terBrugge K et al. Demographic, morphological, and clinical characteristics of 1289 patients with brain arteriovenous malformation. Stroke 2000;31:1307-10.
34. Kim H, McCulloch CE, Johnston SC, Lawton MT, Sidney S, Young WL. Comparison of 2 approaches for determining the natural history risk of brain arteriovenous malformation rupture. Am J Epidemiol 2010;171:1317-22.
35. Crawford PM, West CR, Chadwick DW, Shaw MD. Arteriovenous malformations of the brain: natural history in unoperated patients. J Neurol Neurosurg Psychiatry 1986;49:1-10. (Pubitemid 16155702)
36. Ondra SL, Troupp H, George ED, Schwab K. The natural history of symptomatic arteriovenous malformations of the brain: a 24-year follow-up assessment. J Neurosurg 1990;73:387-91. (Pubitemid 20260008)
37. Stapf C, Mohr JP, Choi JH, Hartmann A, Mast H. Invasive treatment of unruptured brain arteriovenous malformations is experimental therapy. Curr Opin Neurol 2006;19:63-8. (Pubitemid 43172707)
38. Papadias A, Taha A, Sgouros S, Walsh AR, Hockley AD. Incidence of vascular malformations in spontaneous intra-cerebral haemorrhage in children. Childs Nerv Syst 2007;23:881-6.
39. Stapf C, Labovitz DL, Sciacca RR, Mast H, Mohr JP, Sacco RL. Incidence of adult brain arteriovenous malformation hemorrhage in a prospective population-based stroke survey. Cerebrovasc Dis 2002;13:43-6. (Pubitemid 34124170)
40. Kumar R, Shukla D, Mahapatra AK. Spontaneous intracranial hemorrhage in children. Pediatr Neurosurg 2009;45:37-45.
41. ApSimon HT, Reef H, Phadke RV, Popovic EA. A population-based study of brain arteriovenous malformation: long-term treatment outcomes. Stroke 2002;33:2794-800. (Pubitemid 35462846)
42. Kim H, Sidney S, McCulloch CE, Poon KY, Singh V, Johnston SC et al. Racial/Ethnic differences in longitudinal risk of intracranial hemorrhage in brain arteriovenous malformation patients. Stroke 2007;38:2430-7. (Pubitemid 47329618)
43. Stapf C, Mast H, Sciacca RR, Choi JH, Khaw AV, Connolly ES et al. Predictors of hemorrhage in patients with untreated brain arteriovenous malformation. Neurology 2006;66:1350-5.
44. Karlsson B, Lindquist C, Johansson A, Steiner L. Annual risk for the first hemorrhage from untreated cerebral arteriovenous malformations. Minim Invasive Neurosurg 1997;40:40-6. (Pubitemid 27296955)
45. Kader A, Young WL, Pile-Spellman J, , Mast H, Sciacca RR, Mohr JP et al. The influence of hemodynamic and anatomic factors on hemorrhage from cerebral arteriovenous malformations. Neurosurgery 1994;34:801-7.
46. Fleetwood IG, Marcellus ML, Levy RP, Marks MP, Steinberg GK. Deep arteriovenous malformations of the basal ganglia and thalamus: natural history. J Neurosurg 2003,98:747-50. (Pubitemid 36401551)
47. Stefani MA, Porter PJ, TerBrugge KG, Montanera W, Willinsky RA, Wallace MC. Angioarchitectural factors present in brain arteriovenous malformations associated with hemorrhagic presentation. Stroke 2002;33:920-4. (Pubitemid 34293568)
48. Duong DH, Young WL, Vang MC, Sciacca RR, Mast H, Koennecke HC et al. Feeding artery pressure and venous drainage pattern are primary determinants of hemorrhage from cerebral arteriovenous malformations. Stroke 1998;29:1167-76.
49. Stapf C, Mohr JP, Pile-Spellman J, Sciacca RR, Hartmann A, Schumacher HC et al. Concurrent arterial aneurysms in brain arteriovenous malformations with haemorrhagic presentation. J Neurol Neurosurg Psychiatry 2002;73:294-8.
50. Mast H, Mohr JP, Osipov A, Pile-Spellman J, Marshall RS, Lazar RM et al. 'Steal' is an unestablished mechanism for the clinical presentation of cerebral arteriovenous malformations. Stroke 1995;26:1215-20.
51. Stapf C, Khaw AV, Sciacca RR, Hofmeister C, Schumacher HC, Pile-Spellman J et al. Effect of age on clinical and morphological characteristics in patients with brain arteriovenous malformation. Stroke 2003;34:2664-9. (Pubitemid 37392762)
52. Hoh BL, Chapman PH, Loeffler JS, Carter BS, Ogilvy CS. Results of multimodality treatment for 141 patients with brain arteriovenous malformations and seizures: factors associated with seizure incidence and seizure outcomes. Neurosurgery 2002;51:303-9.
53. Ghossoub M, Nataf F, Merienne L, Devaux B, Turak B, Roux FX. [Characteristics of headache associated with cerebral arteriovenous malformations]. Neurochirurgie 2001;47(2-3 Pt 2):177-83.
54. Choi JH, Mast H, Hartmann A, Marshall RS, Pile-Spellman J, Mohr JP et al. Clinical and morphological determinants of focal neurological deficits in patients with unruptured brain arteriovenous malformation. J Neurol Sci 2009;287:126-30.
55. Pollock BE, Flickinger JC, Lunsford LD, Bissonette DJ, Kondziolka D. Factors that predict the bleeding risk of cerebral arteriovenous malformations. Stroke 1996;27:1-6.
56. Brown RD, Jr., Wiebers DO, Forbes G, O'Fallon WM, Piepgras DG, Marsh WR et al. The natural history of unruptured intracranial arteriovenous malformations. J Neurosurg 1988;68:352-7. (Pubitemid 18067633)
57. Graf CJ, Perret GE, Tomer JC. Bleeding from cerebral arteriovenous malformations as part of their natural history. J Neurosurg 1983;58:331-7. (Pubitemid 13149533)
58. Mattle HP, Schroth G, Seiler RW. Dilemmas in the management of patients with arteriovenous malformations. J Neurol 2000;247:917-28. (Pubitemid 32042658)
59. Itoyama Y, Uemura S, Ushio Y, Kuratsu J, Nonaka N, Wada H et al. Natural course of unoperated intracranial arteriovenous malformations: study of 50 cases. J Neurosurg 1989;71:805-9. (Pubitemid 20008557)
60. Yamada S, Takagi Y, Nozaki K, Kikuta K, Hashimoto N. Risk factors for subsequent hemorrhage in patients with cerebral arteriovenous malformations. J Neurosurg 2007;107:965-72. (Pubitemid 350255210)
61. Hernesniemi JA, Dashti R, Juvela S, Vaart K, Niemela M, Laakso A. Natural history of brain arteriovenous malformations: a longterm follow-up study of risk of hemorrhage in 238 patients. Neurosurgery 2008;63.823-9.
62. Jayaraman MV, Marcellus ML, Do HM, Chang SD, Rosenberg JK, Steinberg GK et al. Hemorrhage rate in patients with Spetzler-Martin grades IV and V arteriovenous malformations: is treatment justified? Stroke 2007;38:325-9.
63. Stefani MA, Porter PJ, TerBrugge KG, Montanera W, Willinsky RA, Wallace MC. Large and deep brain arteriovenous malformations are associated with risk of future hemorrhage. Stroke 2002;33:1220-4. (Pubitemid 34517039)
64. Langer DJ, Lasner TM, Hurst RW, Flamm ES, Zager EL, King JT, Jr. Hypertension, small size, and deep venous drainage are associated with risk of hemorrhagic presentation of cerebral arteriovenous malformations. Neurosurgery 1998;42:481-6.
65. Achrol AS, Pawlikowska L, McCulloch CE, Poon KY, Ha C, Zaroff JG et al. Tumor necrosis factor-alpha-238G>A promoter polymorphism is associated with increased risk of new hemorrhage in the natural course of patients with brain arteriovenous malformations. Stroke 2006;37:231-4. (Pubitemid 43732078)
66. Pawlikowska L, Poon KY, Achrol AS, McCulloch CE, Ha C, Lum K et al. Apolipoprotein E epsilon 2 is associated with new hemorrhage risk in brain arteriovenous malformations. Neurosurgery 2006;58:838-43.
67. Brown RD, Jr. Simple risk predictions for arteriovenous malformation hemorrhage. Neurosurgery 2000;46:1024.
68. Kondziolka D, McLaughlin MR, Kestle JR. Simple risk predictions for arteriovenous malformation hemorrhage. Neurosurgery 1995;37:851-5.
69. Choi JH, Mast H, Sciacca RR, Hartmann A, Khaw AV, Mohr JP et al. Clinical outcome after first and recurrent hemorrhage in patients with untreated brain arteriovenous malformation. Stroke 2006;37:1243-7.
70. Cockroft KM. Unruptured cerebral arteriovenous malformations: to treat or not to treat. Stroke 2006;37:1148-9. (Pubitemid 43731844)
71. Halim AX, Johnston SC, Singh V, McCulloch CE, Bennett JP, Achrol AS et al. Longitudinal risk of intracranial hemorrhage in patients with arteriovenous malformation of the brain within a defined population. Stroke 2004;35:1697-702. (Pubitemid 38823650)
72. Hartmann A, Mast H, Mohr JP, Stapf C, Mohr JP. Morbidity of intracranial hemorrhage in patients with cerebral arteriovenous malformation. Stroke 1998;29:931-4. (Pubitemid 28228151)
73. Al-Shahi R, Stapf C. The prognosis and treatment of arteriovenous malformations of the brain. Pract Neurol 2005;5:194-205. (Pubitemid 41150369)
74. Cockroft KM. Unruptured brain arteriovenous malformations should be treated conservatively: no. Stroke 2007;38:3310-1.
75. Morgan M, Sekhon L, Rahman Z, Dandie G. Morbidity of intracranial hemorrhage in patients with cerebral arteriovenous malformation. Stroke 1998;29:2001-2. (Pubitemid 28400011)
76. Pavesi G, Rustemi O, Berlucchi S, Frigo AC, Gerunda V, Scienza R. Acute surgical removal of low-grade (Spetzler-Martin I-II) bleeding arteriovenous malformations. Surg Neurol 2009;72:662-7.
77. Miller CE, Quayyum Z, McNamee P, Al-Shahi Salman R, on behalf of the SIVMS Steering Committee. Economic burden of intracranial vascular malformations in adults: prospective population-based study. Stroke 2009;40:1973-9.
78. Buis DR, Berg Rvd, Lycklama G, van der Worp HB, Dirven CM, Vandertop WP. Spontaneous regression of brain arteriovenous malformations - a clinical study and a systematic review of the literature. J Neurol 2004;251:1375-82.
79. Tanabe S, Uede T, Nonaka T, Ohtaki M, Hashi K. Diagnosis of cerebral arteriovenous malformations with three-dimensional CT angiography. J Clin Neurosci 1998;5(Supplement 1):33-38.
80. Griffiths PD, Beveridge CJ, Gholkar A. Angiography in non-traumatic brain haematoma. An analysis of 100 cases. Acta Radiol 1997;38(5):797-802.
81. Hino A, Fujimoto M, Yamaki T, Iwamoto Y, Katsumori T. Value of repeat angiography in patients with spontaneous subcortical hemorrhage. Stroke 1998;29(12):2517-2521. (Pubitemid 28544001)
82. Willinsky RA, Fitzgerald M, TerBrugge K, Montanera W, Wallace M. Delayed angiography in the investigation of intracerebral hematomas caused by small arteriovenous malformations. Neuroradiology 1993;35(4):307-311. (Pubitemid 23120655)
83. Osipov A, Koennecke H-C, Hartmann A et al. Seizures in cerebral arteriovenous aalformations: type, clinical course and medical management. Interventional Neuroradiology 1997;3:37-41.
84. Starke RM, Komotar RJ, Hwang BY et al. Treatment guidelines for cerebral arteriovenous malformation microsurgery. Br J Neurosurg 2009;23:376-86.
85. Yasargil MG. History. In: Yasargil MG, editor. Microneurosurgery IIIA. AVM of the Brain: History, Embryology, Pathological Considerations, Hemodynamics, Diagnostic Studies, Microsurgical Anatomy. 1 ed. Stuttgart New York: Thieme Verlag; 1987 p. 3-22.
86. Doby T. Cerebral angiography and Egas Moniz. AJR Am J Roentgenol 1992;159:364.
87. Forster DM, Steiner L, Hakanson S. Arteriovenous malformations of the brain. A long-term clinical study. J Neurosurg 1972;37:562-70.
88. Ligon BL. The mystery of angiography and the "unawarded" Nobel Prize: Egas Moniz and Hans Christian Jacobaeus. Neurosurgery 1998;43:602-11.
89. Reinacher PC, Stracke P, Reinges MH, Hans FJ, Krings T. Contrast-enhanced time-resolved 3-D MRA: applications in neurosurgery and interventional neuroradiology. Neuroradiology 2007;49 Suppl 1:S3-13.
90. Heros RC, Korosue K, Diebold PM. Surgical excision of cerebral arteriovenous malformations: late results. Neurosurgery 1990;26:570-7.
91. Lawton MT. Spetzler-Martin Grade III arteriovenous malformations: surgical results and a modification of the grading scale. Neurosurgery 2003;52:740-8.
92. Lawton MT, Kim H, McCulloch CE, Mikhak B, Young WL. A supplementary grading scale for selecting patients with brain arteriovenous malformations for surgery. Neurosurgery 2010;66:702-13.
93. Spetzler RF, Ponce FA. A 3-tier classification of cerebral arteriovenous malformations. J Neurosurg 2010; 1-8.
94. Morgan MK, Rochford AM, Tsahtsarlis A, Little N, Faulder KC. Surgical risks associated with the management of Grade I and II brain arteriovenous malformations. Neurosurgery 2004;54:832-7.
95. Hartmann A, Stapf C, Hofmeister C, Mohr JP, Sciacca RR, Stein BM et al. Determinants of neurological outcome after surgery for brain arteriovenous malformation. Stroke 2000;31:2361-4.
96. Davidson ASM, Morgan MK. How safe is arteriovenous malformation surgery? A prospective, observational study of surgery as first-line treatment for brain arteriovenous malformations. Neurosurgery 2010;66.
97. Han PP, Ponce FA, Spetzler RF. Intention-to-treat analysis of Spetzler-Martin grades IV and V arteriovenous malformations: natural history and treatment paradigm. J Neurosurg 2003,98:3-7.
98. Heros RC. Spetzler-Martin grades IV and V arteriovenous malformations. J Neurosurg 2003;98:1-2. (Pubitemid 36050439)
99. Klopfenstein JD, Spetzler RF. Cerebral arteriovenous malformations: when is surgery indicated? Acta Neurochir (Wien) 2005;147:693-5.
100. Spetzler RF, Martin NA. A proposed grading system for arteriovenous malformations. 1986. J Neurosurg 2008;108:186-93.
101. Spetzler RF. Arteriovenous malformation grading system. J Neurosurg 2008;108:185.
102. Zhao J, Yu T, Wang S, Zhao Y, Yang WY. Surgical treatment of giant intracranial arteriovenous malformations. Neurosurgery 2010;67:1359-70.
103. Bristol RE, Albuquerque FC, McDougall CG. The evolution of endovascular treatment for intracranial arteriovenous malformations. Neurosurg Focus 2006;20:E6.
104. Ayad M, Eskioglu E, Mericle RA. OnyxR: a unique neuroembolic agent. Expert Rev Med Devices 2006;3:705-15.
105. Loh Y, Duckwiler GR. A prospective, multicenter, randomized trial of the Onyx liquid embolic system and N-butyl cyanoacrylate embolization of cerebral arteriovenous malformations. J Neurosurg 2010;113:733-41.
106. Haw CS, TerBrugge K, Willinsky R, Tomlinson G. Complications of embolization of arteriovenous malformations of the brain. J Neurosurg 2006;104:226-32.
107. van Rooij WJ, Sluzewski M, Beute GN. Brain AVM Embolization with Onyx. AJNR Am J Neuroradiol 2007;28:172-7.
108. Katsaridis V, Papagiannaki C, Aimar E. Curative embolization of cerebral arteriovenous malformations (AVMs) with Onyx in 101 patients. Neuroradiology 2008;50:589-97.
109. Jayaraman MV, Marcellus ML, Hamilton S, Do HM, Campbell D, Chang SD et al. Neurologic complications of arteriovenous malformation embolization using liquid embolic agents. AJNR Am J Neuroradiol 2008;29:242-6. (Pubitemid 351287874)
110. Kim LJ, Albuquerque FC, Spetzler RF, McDougall CG. Postembolization neurological deficits in cerebral arteriovenous malformations: stratification by arteriovenous malformation grade. Neurosurgery 2006;59:53-9.
111. Ledezma CJ, Hoh BL, Carter BS, Pryor JC, Putman CM, Ogilvy CS. Complications of cerebral arteriovenous malformation embolization: multivariate analysis of predictive factors. Neurosurgery 2006;58:602-11.
112. Weber W, Kis B, Siekmann R, Jans P, Laumer R, Kuhne D. Preoperative embolization of intracranial arteriovenous malformations with Onyx. Neurosurgery 2007;61:244-52. (Pubitemid 47357292)
113. Fiorella D, Albuquerque FC, Woo HH, McDougall CG, Rasmussen PA. The role of neuroendovascular therapy for the treatment of brain arteriovenous malformations. Neurosurgery 2006;59(5 Suppl 3):S163-S177.
114. Vinuela F, Fox AJ, Pelz D, Debrun G. Angiographic follow-up of large cerebral AVMs incompletely embolized with isobutyl-2-cyanoacrylate. AJNR Am J Neuroradiol 1986;7(5):919-925. (Pubitemid 17172057)
115. Chang SD, Shuster DL, Steinberg GK, Levy RP, Frankel K. Stereotactic radiosurgery of arteriovenous malformations: pathologic changes in resected tissue. Clin Neuropathol 1997;16:111-6.
116. Schneider BF, Eberhard DA, Steiner LE. Histopathology of arteriovenous malformations after gamma knife radiosurgery. J Neurosurg 1997;87:352-7. (Pubitemid 27362565)
117. Steinberg GK, Chang SD, Levy RP, Marks MP, Frankel K, Marcellus M. Surgical resection of large incompletely treated intracranial arteriovenous malformations following stereotactic radiosurgery. J Neurosurg 1996;84:920-8. (Pubitemid 26159106)
118. Shin M, Maruyama K, Kurita H, Kawamoto S, Tago M, Terahara A et al. Analysis of nidus obliteration rates after gamma knife surgery for arteriovenous malformations based on long-term follow-up data: the University of Tokyo experience. J Neurosurg 2004;101:18-24. (Pubitemid 38808455)
119. Zabel-du Bois A, Milker-Zabel S, Huber P, Schlegel W, Debus J. Risk of hemorrhage and obliteration rates of LINAC-based radiosurgery for cerebral arteriovenous malformations treated after prior partial embolization. Int J Radiat Oncol Biol Phys 2007;68:999-1003. (Pubitemid 47048562)
120. Zabel A, Milker-Zabel S, Huber P, Schulz-Ertner D, Schlegel W, Debus J. Treatment outcome after linac-based radiosurgery in cerebral arteriovenous malformations: retrospective analysis of factors affecting obliteration. Radiother Oncol 2005;77:105-10. (Pubitemid 41503398)
121. Pollock BE, Gorman DA, Coffey RJ. Patient outcomes after arteriovenous malformation radiosurgical management: results based on a 5- to 14-year follow-up study. Neurosurgery 2003;52:1291-6.
122. Raza SM, Jabbour S, Thai QA et al. Repeat stereotactic radiosurgery for high-grade and large intracranial arteriovenous malformations. Surg Neurol 2007;68:24-34.
123. Liscak R, Vladyka V, Simonová G, Urgosík D, Novotný J Jr, Janousková L et al. Arteriovenous malformations after Leksell gamma knife radiosurgery: rate of obliteration and complications. Neurosurgery 2007;60:1005-14.
124. Han JH, Kim DG, Chung HT, Park CK, Paek SH, Kim JE et al. Clinical and neuroimaging outcome of cerebral arteriovenous malformations after Gamma Knife surgery: analysis of the radiation injury rate depending on the arteriovenous malformation volume. J Neurosurg 2008;109:191-8.
125. Blanchard N, Bernier V, Anxionnat R et al. [Radiosurgery of cerebral arteriovenous malformations: a prescription algorithm]. Cancer Radiother 2009;13:1-10.
126. Ganz JC, Reda WA, Abdelkarim K, Hafez A. A simple method for predicting imaging-based complications following gamma knife surgery for cerebral arteriovenous malformations. J Neurosurg 2005; 102 Suppl:4-7.
127. Friedman WA, Bova FJ, Bollampally S, Bradshaw P. Analysis of factors predictive of success or complications in arteriovenous malformation radiosurgery. Neurosurgery 2003;52:296-307.
128. Izawa M, Hayashi M, Chernov M, Iseki H, Hori T, Takakura K et al. Long-term complications after gamma knife surgery for arteriovenous malformations. J Neurosurg 2005;102 Suppl:34-37.
129. Yamamoto M, Jimbo M, Hara M, Saito I, Mori K. Gamma knife radiosurgery for arteriovenous malformations: long-term follow-up results focusing on complications occurring more than 5 years after irradiation. Neurosurgery 1996;38:906-14.
130. Pollock BE, Brown RD, Jr. Management of cysts arising after radiosurgery to treat intracranial arteriovenous malformations. Neurosurgery 2001;49:259-64.
131. Edmister WB, Lane JI, Gilbertson JR, Brown RD, Pollock BE. Tumefactive cysts: a delayed complication following radiosurgery for cerebral arterial venous malformations. AJNR Am J Neuroradiol 2005;26:1152-7.
132. Schlienger M, Nataf F, Lefkopoulos D, Mammar H, Missir O, Meder JF et al. Repeat linear accelerator radiosurgery for cerebral arteriovenous malformations. Int J Radiat Oncol Biol Phys 2003;56:529-36.
133. Pollock BE, Flickinger JC. A proposed radiosurgery-based grading system for arteriovenous malformations. J Neurosurg 2002;96:79-85.
134. Pollock BE, Flickinger JC. Modification of the radiosurgery-based arteriovenous malformation grading system. Neurosurgery 2008;63:239-43.
135. Kwon Y, Jeon SR, Kim JH, Lee JK, Ra DS, Lee DJ et al. Analysis of the causes of treatment failure in gamma knife radiosurgery for intracranial arteriovenous malformations. J Neurosurg 2000;93 Suppl 3:104-6.
136. Pollock BE, Kondziolka D, Lunsford LD, Bissonette D, Flickinger JC. Repeat stereotactic radiosurgery of arteriovenous malformations: factors associated with incomplete obliteration. Neurosurgery 1996;38:318-24.
137. Flickinger JC, Pollock BE, Kondziolka D, Lunsford LD. A dose-response analysis of arteriovenous malformation obliteration after radiosurgery. Int J Radiat Oncol Biol Phys 1996;36.873-9.
138. Flickinger JC, Kondziolka D, Maitz AH, Lunsford LD. An analysis of the dose-response for arteriovenous malformation radiosurgery and other factors affecting obliteration. Radiother Oncol 2002;63:347-54.
139. Zipfel GJ, Bradshaw P, Bova FJ, Friedman WA. Do the morphological characteristics of arteriovenous malformations affect the results of radiosurgery? J Neurosurg 2004;101:393-401.
140. Buis DR, Lagerwaard FJ, Barkhof F, Dirven CM, Lycklama GJ, Meijer OW et al. Stereotactic radiosurgery for brain AVMs: role of interobserver variation in target definition on digital subtraction angiography. Int J Radiat Oncol Biol Phys 2005,62:246-52.
141. Buis DR, Lagerwaard FJ, Dirven CM, Barkhof F, Knol DL, van den Berg R et al. Delineation of brain AVMs on MR-Angiography for the purpose of stereotactic radiosurgery. Int J Radiat Oncol Biol Phys 2007;67:308-16.
142. Bova FJ, Friedman WA. Stereotactic angiography: an inadequate database for radiosurgery? Int J Radiat Oncol Biol Phys 1991;20:891-5.
143. Maitz AH, Niranjan A, Jungreis CA, Kondziolka D, Flickinger JC, Lunsford LD. Tube angulation improves angiographic targeting of arteriovenous malformations during stereotactic radiosurgery. Comput Aided Surg 2001;6:225-9.
144. Andrade-Souza YM, Ramani M, Scora D, Tsao MN, TerBrugge K, Schwartz ML. Embolization before radiosurgery reduces the obliteration rate of arteriovenous malformations. Neurosurgery 2007;60:443-51.
145. Pollock BE, Kline RW, Stafford SL, Foote RL, Schomberg PJ. The rationale and technique of staged-volume arteriovenous malformation radiosurgery. Int J Radiat Oncol Biol Phys 2000;48:817-24.
146. Jones J, Jang S, Getch CC, Kepka AG, Marymont MH. Advances in the radiosurgical treatment of large inoperable arteriovenous malformations. Neurosurg Focus 2007;23:E6.
147. Friedman WA, Bova FJ, Mendenhall WM. Linear accelerator radiosurgery for arteriovenous malformations: the relationship of size to outcome. J Neurosurg 1995;82:180-9.
148. Flickinger JC, Schell MC, Larson DA. Estimation of complications for linear accelerator radiosurgery with the integrated logistic formula. Int J Radiat Oncol Biol Phys 1990;19:143-8.
149. Sirin S, Kondziolka D, Niranjan A, Flickinger JC, Maitz AH, Lunsford LD. Prospective staged volume radiosurgery for large arteriovenous malformations: indications and outcomes in otherwise untreatable patients. Neurosurgery 2006;58:17-27.
150. Xiao F, Gorgulho AA, Lin CS, Chen CH, Agazaryan N, Vinuela F et al. Treatment of giant cerebral arteriovenous malformation: hypofractionated stereotactic radiation as the first stage. Neurosurgery 2010;67:1253-9.
151. Zabel-du Bois A, Milker-Zabel S, Huber P, Schlegel W, Debus J. Linac-based radiosurgery or hypofractionated stereotactic radiotherapy in the treatment of large cerebral arteriovenous malformations. Int J Radiat Oncol Biol Phys 2006;64:1049-54.
152. Brenner DJ, Martel MK, Hall EJ. Fractionated regimens for stereotactic radiotherapy of recurrent tumors in the brain. Int J Radiat Oncol Biol Phys 1991;21:819-24.
153. Aoyama H, Shirato H, Nishioka T, Kagei K, Onimaru R, Suzuki K et al. Treatment outcome of single or hypofractionated single-isocentric stereotactic irradiation (STI) using a linear accelerator for intracranial arteriovenous malformation. Radiother Oncol 2001;59:323-8.
154. Chang TC, Shirato H, Aoyama H, Ushikoshi S, Kato N, Kuroda S et al. Stereotactic irradiation for intracranial arteriovenous malformation using stereotactic radiosurgery or hypofractionated stereotactic radiotherapy. Int J Radiat Oncol Biol Phys 2004;60:861-70.
155. Lindvall P, Bergström P, Löfroth PO, Hariz MI, Henriksson R, Jonasson P et al. Hypofractionated conformal stereotactic radiotherapy for arteriovenous malformations. Neurosurgery 2003:53:1036-42.
156. Nakstad PH, Nornes H. Superselective angiography, embolisation and surgery in treatment of arteriovenous malformations of the brain. Neuroradiology 1994;36:410-3.
157. Spetzler RF, Martin NA, Carter LP, Flom RA, Raudzens PA, Wilkinson E. Surgical management of large AVM's by staged embolization and operative excision. J Neurosurg 1987;67:17-28.
158. Uno M, Satoh K, Matsubara S, Satomi J, Nakajima N, Nagahiro S. Does multimodaliry therapy of arteriovenous malformations improve patient outcome? Neurol Res 2004;26:50-4.
159. Zhao J, Wang S, Li J, Qi W, Sui D, Zhao Y. Clinical characteristics and surgical results of patients with cerebral arteriovenous malformations. Surg Neurol 2005;63:156-61.
160. Bollet MA, Anxionnat R, Buchheit I, Bey P, Cordebar A, Jay N et al. Efficacy and morbidity of arc-therapy radiosurgery for cerebral arteriovenous malformations: a comparison with the natural history. Int J Radiat Oncol Biol Phys 2004;58:1353-63.
161. Viñuela F, Dion JE, Duckwiler G, Martin NA, Lylyk P, Fox A et al. Combined endovascular embolization and surgery in the management of cerebral arteriovenous malformations: experience with 101 cases. J Neurosurg 1991;75:856-64.
162. Chang SD, Marcellus ML, Marks MP, Levy RP, Do HM, Steinberg GK. Multimodality treatment of giant intracranial arteriovenous malformations. Neurosurgery 2003;531-11.
163. Smith KA, Shetter A, Speiser B, Spetzler RF. Angiographic follow-up in 37
164. Miyamoto S, Hashimoto N, Nagata I, Nozaki K, Morimoto M, Taki W et al. Posttreatment sequelae of palliatively treated cerebral arteriovenous malformations. Neurosurgery 2000;46:589-94.
165. Heros RC. Re: Multimodality treatment of posterior fossa arteriovenous malformations. J Neurosurg 2008;108:1148-51.
166. Kelly ME, Guzman R, Sinclair J, Bell-Stephens TE, Bower R, Hamilton S et al. Multimodality treatment of posterior fossa arteriovenous malformations. J Neurosurg 2008;108:1152-61.
167. Wedderburn CJ, van BJ, Bhattacharya JJ, Counsell CE, Papanastassiou V, Ritchie V et al. Outcome after interventional or conservative management of unruptured brain arteriovenous malformations: a prospective, population-based cohort study. Lancet Neurol 2008;7:223-30.
168. Brown RD, Jr. Unruptured brain AVMs: to treat or not to treat. Lancet Neurol 2008;7:195-6.
169. Ross J, Al-Shahi SR. Interventions for treating brain arteriovenous malformations in adults. Cochrane Database Syst Rev 2010;CD003436.
170. Mohr JP. A randomized trial of unruptured brain arteriovenous malformations (ARUBA). Acta Neurochir Suppl 2008;103:3-4.
171. Stapf C. The rationale behind "A Randomized Trial of Unruptured Brain AVMs" (ARUBA). Acta Neurochir Suppl 2010;107:83-5.
172. Murphy PA, Lam MTY, Wu X, Kim TN, Vartanian SM, Bollen AW et al. Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice. Proc Natl Acad Sci U S A 2008;105:10901-6.
173. Fee D, Grzybicki D, Dobbs M et al. Interleukin 6 promotes vasculogenesis of murine brain microvessel endothelial cells. Cytokine 2000;12:655-65.
174. Yao JS, Zhai W, Young WL, Yang GY. Interleukin-6 triggers human cerebral endothelial cells proliferation and migration: the role for KDR and MMP-9. Biochem Biophys Res Commun 2006;342:1396-404.
175. Wei LH, Kuo ML, Chen CA,, Chou CH, Lai KB, Lee CN et al. Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway. Oncogene 2003;22:1517-27.
176. Cohen T, Nahari D, Cerem LW, Neufeld G, Levi BZ. Interleukin 6 induces the expression of vascular endothelial growth factor. J Biol Chem 1996;271:736-41.
177. Pawlikowska L, Tran MN, Achrol AS, McCulloch CE, Ha C, Lind DL et al. Polymorphisms in genes involved in inflammatory and angiogenic pathways and the risk of hemorrhagic presentation of brain arteriovenous malformations. Stroke 2004;35:2294-300.
178. Chen Y, Pawlikowska L, Yao JS, Shen F, Zhai W, Achrol AS et al. Interleukin-6 involvement in brain arteriovenous malformations. Ann Neurol 2006;59:72-80.
179. Hayashi T, Noshita N, Sugawara T, Chan PH. Temporal profile of angiogenesis and expression of related genes in the brain after ischemia. J Cereb Blood Flow Metab 2003;23:166-80.
180. Zhang ZG, Zhang L, Jiang Q, Zhang R, Davies K, Powers C et al. VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain. J Clin Invest 2000;106:829-38.
181. Hashimoto T, Emala CW, Joshi S et al. Abnormal pattern of Tie-2 and vascular endothelial growth factor receptor expression in human cerebral arteriovenous malformations. Neurosurgery 2000;47:910-8.
182. Lee CZ, Xue Z, Zhu Y, Yang GY, Young WL. Matrix metalloproteinase-9 inhibition attenuates vascular endothelial growth factor-induced intracerebral hemorrhage. Stroke 2007;38:2563-68.
183. Yang GY, Xu B, Hashimoto T, Huey M, Chaly T Jr, Wen R et al. Induction of focal angiogenesis through adenoviral vector mediated vascular endothelial cell growth factor gene transfer in the mature mouse brain. Angiogenesis 2003;6:151-8.
184. Asahi M, Wang X, Mori T, Sumii T, Jung JC, Moskowitz MA et al. Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci 2001;21:7724-32.
185. Hamann GF, Okada Y, del Zoppo GJ. Hemorrhagic transformation and microvascular integrity during focal cerebral ischemia/ reperfusion. J Cereb Blood Flow Metab 1996;16:1373-8.
186. Montaner J, Alvarez-Sabín J, Molina CA, Anglés A, Abilleira S, Arenillas J et al. Matrix metalloproteinase expression is related to hemorrhagic transformation after cardioembolic stroke. Stroke 2001;32:2762-7.
187. Hashimoto T, Matsumoto MM, Li JF, Lawton MT, Young WL. Suppression of MMP-9 by doxycycline in brain arteriovenous malformations. BMC Neurol 2005;5:1.
188. Lang CT, King JC. Maternal mortality in the United States. Best Pract Res Clin Obstet Gynaecol 2008;22:517-31.
189. Sharshar T, Lamy C, Mas JL. Incidence and causes of strokes associated with pregnancy and Puerperium. A study in public hospitals of Ile de France. Stroke in Pregnancy Study Group. Stroke 1995;26:930-6.
190. Liang CC, Chang SD, Lai SL, Hsieh CC, Chueh HY, Lee TH. Stroke complicating pregnancy and the Puerperium. Eur J Neurol 2006;13:1256-60.
191. Davie CA, O'Brien P. Stroke and pregnancy. J Neurol Neurosurg Psychiatry 2008;79:240-5.
192. Finnerty JJ, Chisholm CA, Chappie H, Login IS, Pinkerton JV. Cerebral arteriovenous malformation in pregnancy: Presentation and neurologic, obstetric, and ethical significance, . Am J Obstet Gynecol 1999;181:296-303.
193. Horton JC, Chambers WA, Lyons SL, Adams RD, Kjellberg RN. Pregnancy and the risk of hemorrhage from cerebral arteriovenous malformations. Neurosurgery 1990;27:867-71.
194. Robinson JL, Hall CS, Sedzimir CB. Arteriovenous malformations, aneurysms, and pregnancy. J Neurosurg 1974;41:63-70.
195. Trivedi RA, Kirkpatrick PJ. Arteriovenous malformations of the cerebral circulation that rupture in pregnancy. J Obstet Gynaecol 2003;23:484-9.
196. Dias MS, Sekhar LN. Intracranial hemorrhage from aneurysms and arteriovenous malformations during pregnancy and the Puerperium. Neurosurgery 1990;27:855-65.
197. Lanzino G, Jensen ME, Cappelletto B, Kassell NF. Arteriovenous malformations that rapture during pregnancy: a management dilemma. Acta Neurochir (Wien) 1994;126:102-6.
198. Dias MS. Neurovascular emergencies in pregnancy. Clin Obstet Gynecol 1994;37:337-54.
199. Forster DM, Kunkler IH, Hartland P. Risk of cerebral bleeding from arteriovenous malformations in pregnancy: the Sheffield experience. Stereotact Funct Neurosurg 1993;61 Suppl 1:20-2.
200. Ng J, Kitchen N. Neurosurgery and pregnancy. J Neurol Neurosurg Psychiatry 2008;79:745-52.
201. Wiebers DO. Subarachnoid hemorrhage in pregnancy. Semin Neurol 1988;8:226-9.
202. Perquin DA, Kloet A, Tans JT, Witte GN, Dorr PJ. [Intracranial arteriovenous malformations in pregnant women]. Ned Tijdschr Geneeskd 1999;143:497-500.
203. The Arteriovenous Malformation Study Group. Arteriovenous malformations of the brain in adults. N Engl J Med 1999;340:1812-8.
204. Lasjaunias P, Hui F, Zerah M, Garcia-Monaco R, Malherbe V, Rodesch G et al. Cerebral arteriovenous malformations in children. Management of 179 consecutive cases and review of the literature. Childs Nerv Syst 1995;11:66-79.
205. Rodesch G, Malherbe V, Alvarez H, Zerah M, Devictor D, Lasjaunias P. Nongalenic cerebral arteriovenous malformations in neonates and infants. Review of 26 consecutive cases (1982-1992). Childs Nerv Syst 1995;11:231-41.
206. Sheikh BY, Hassounah M, Al-Moutare K, Ammar A, Enazi A. Childhood intracranial arteriovenous malformation in Saudi Arabia. Childs Nerv Syst 1999;15:262-6. (Pubitemid 29260600)
207. Nicolato A, Lupidi F, Sandri MF, Foroni R, Zampieri P, Mazza C et al. Gamma knife radiosurgery for cerebral arteriovenous malformations in children/adolescents and adults. Part I: Differences in epidemiologic, morphologic, and clinical characteristics, permanent complications, and bleeding in the latency period. Int J Radiat Oncol Biol Phys 2006;64:904-13. (Pubitemid 43183592)
208. Iizuka Y, Rodesch G, Garcia-Monaco R, Alvarez H, Burrows P, Hui F et al. Multiple cerebral arteriovenous shunts in children: report of 13 cases. Childs Nerv Syst 1992;8:437-44. (Pubitemid 23021841)
209. Lasjaunias P, TerBrugge KG, Berenstein A. Cerebral arteriovenous malformations. In: Lasjaunias P, TerBrugge KG, Berenstein A, editors. Surgical neuroangiography 3: Clinical and interventional aspects in children. 2nd edition. Berlin: Springer; 2006 p. 291-358.
210. Garcia-Monaco R, Rodesch G, TerBrugge K, Burrows P, Lasjaunias P. Multifocal dural arteriovenous shunts in children. Childs Nerv Syst 1991;7:425-31.
211. Halim AX, Singh V, Johnston SC, Higashida RT, Dowd CF, Halbach W et al. Characteristics of brain arteriovenous malformations with coexisting aneurysms: a comparison of two referral centers. Stroke 2002;33:675-9.
212. Kim EJ, Halim AX, Dowd CF, Lawton MT, Singh V, Bennett J et al. The relationship of coexisting extranidal aneurysms to intracranial hemorrhage in patients harboring brain arteriovenous malformations. Neurosurgery 2004;54:1349-57.
213. Lasjaunias P, Piske R, TerBrugge K, Willinsky R. Cerebral arteriovenous malformations (C. AVM) and associated arterial aneurysms (AA). Analysis of 101 C. AVM cases, with 37 AA in 23 patients. Acta Neurochir (Wien) 1988,91:29-36.
214. Celli P, Ferrante L, Palma L, Cavedon G. Cerebral arteriovenous malformations in children. Clinical features and outcome of treatment in children and in adults. Surg Neurol 1984;22:43-9.
215. Di Rocco, Tamburrini G, Rollo M. Cerebral arteriovenous malformations in children. Acta Neurochir (Wien) 2000;142:145-56.
216. 253- Kondziolka D, Humphreys RP, Hoffman HJ, Hendrick EB, Drake JM. Arteriovenous malformations of the brain in children: a forty year experience. Can J Neurol Sci 1992;19:40-5.
217. Mori K, Murata T, Hashimoto N, Handa H. Clinical analysis of arteriovenous malformations in children. Childs Brain 1980,6:13-25.
218. Fullerton HJ, Achrol AS, Johnston SC, McCulloch CE, Higashida RT, Lawton MT et al. Long-term hemorrhage risk in children versus adults with brain arteriovenous malformations. Stroke 2005;36:2099-104. (Pubitemid 41429227)
219. Sanchez-Mejia RO, Chennupati SK, Gupta N, Fullerton H, Young WL, Lawton MT. Superior outcomes in children compared with adults after microsurgical resection of brain arteriovenous malformations. J Neurosurg 2006;105(2 Suppl):82-7. (Pubitemid 44954777)
220. Klimo P, Jr., Rao G, Brockmeyer D. Pediatric arteriovenous malformations: a 15-year experience with an emphasis on residual and recurrent lesions. Childs Nerv Syst 2007;23:31-7. (Pubitemid 46138485)
221. Nicolato A, Lupidi F, Sandri MF, Foroni R, Zampieri P, Mazza C et al. Gamma Knife radiosurgery for cerebral arteriovenous malformations in children/adolescents and adults. Part II: Differences in obliteration rates, treatment-obliteration intervals, and prognostic factors. Int J Radiat Oncol Biol Phys 2006;64:914-21. (Pubitemid 43183593)
222. Rodriguez-Arias C, Martinez R, Rey G, Bravo G. Recurrence in a different location of a cerebral arteriovenous malformation in a child after radiosurgery. Childs Nerv Syst 2000;16:363-5. (Pubitemid 30418389)
223. Gabriel EM, Sampson JH, Wilkins RH. Recurrence of a cerebral arteriovenous malformation after surgical excision. J Neurosurg 1996;84.879-82.
224. Freudenstein D, Duffner F, Ernemann U, Rachinger J, Grote E. Recurrence of a cerebral arteriovenous malformation after surgical excision. Cerebrovasc Dis 2001;11:59-64. (Pubitemid 32098429)
225. Patil AA. Angiographic disappearance and reappearance of an arteriovenous malformation of the cerebellum and brain stem, and its surgical excision. A case report. Acta Neurochir (Wien) 1982;62:247-52. (Pubitemid 12057446)
226. Hashimoto N, Nozaki K. Do cerebral arteriovenous malformations recur after angiographically confirmed total extirpation? Crit Rev Neurosurg 1999:9:141-6.
227. Andaluz N, Myseros JS, Sathi S, Crone KR, Tew JM. Recurrence of cerebral arteriovenous malformations in children: Report of two cases and review of the literature. Surg Neurol 2004;62:324-30.
228. Park YS, Kwon JT. Recurrent cerebral arteriovenous malformation in a child : case report and review of the literature. J Korean Neurosurg Soc 2009;45:401-4.
229. Prat R, Galeano I, Conde R, Simal JA, Crdenas E. Surgical removal after first bleeding of an arteriovenous malformation previously obliterated with radiosurgery: case report. Surg Neurol 2009;71:211-4.
230. Matsumoto H, Takeda T, Kohno K, Yamaguchi Y, Kohno K, Takechi A et al. Delayed hemorrhage from completely obliterated arteriovenous malformation after gamma knife radiosurgery. Neurol Med Chir (Tokyo) 2006;46:186-90.
231. Shin M, Kawahara N, Maruyama K, Tago M, Ueki K, Kirino T. Risk of hemorrhage from an arteriovenous malformation confirmed to have been obliterated on angiography after stereotactic radiosurgery. J Neurosurg 2005;102:842-6. (Pubitemid 43194003)
232. Lindqvist M, Karlsson B, Guo WY, Kihlstrom L, Lippitz B, Yamamoto M. Angiographic long-term follow-up data for arteriovenous malformations previously proven to be obliterated after gamma knife radiosurgery. Neurosurgery 2000;46:803-8.
233. Abu-Salma Z, Nataf F, Ghossoub M, Schlienger M, Meder JF, Houdart E et al. The protective status of subtotal obliteration of arteriovenous malformations after radiosurgery: significance and risk of hemorrhage. Neurosurgery 2009,65:709-17.
234. Yen CP, Varady P, Sheehan J, Steiner M, Steiner L. Subtotal obliteration of cerebral arteriovenous malformations after gamma knife surgery. J Neurosurg 2007;106:361-9. (Pubitemid 46354287)