Health risk associated with dietary co-exposure to high levels of antimony and arsenic in the world's largest antimony mine area

Science of the Total Environment

Volumn 409, Issue 18, 2011, Pages 3344-3351

  Wu, Fengchang ^a   Fu, Zhiyou ^a   Liu, Bijun ^a   Mo, Changli ^a   Chen, Bin ^b   Corns, Warren ^b   Liao, Haiqing ^a  

^a CHINESE RESEARCH ACADEMY OF ENVIRONMENTAL SCIENCES   (China)

^b P S Analytical Ltd   (United Kingdom)

Author keywords

Antimony; Antimony mine area; Arsenic; Dietary exposure; Health risk

Indexed keywords

ADVERSE EFFECT; ANTIMONATE; COMBINED EFFECT; CRITICAL LEVEL; DIETARY EXPOSURE; DIETARY INTAKES; ESTIMATED DIETARY INTAKES; EXPOSURE CHARACTERISTICS; FOOD SAMPLES; GENOTOXIC; HUMAN EXPOSURES; HUMAN HAIR; HUMAN HEALTH; IN-VITRO; LEAFY VEGETABLES; LOCAL RESIDENTS; PILOT STUDIES; TOLERABLE DAILY INTAKE; XIKUANGSHAN;

ANTIMONY; ANTIMONY MINES; ARSENIC; CHEMICAL CONTAMINATION; HEALTH; HEALTH HAZARDS; POTABLE WATER; VEGETABLES;

HEALTH RISKS;

ANTIMONY; ARSENIC; DRINKING WATER;

ANTIMONY; ARSENIC; BIOACCUMULATION; GENOTOXICITY; HEALTH RISK; POLLUTION EXPOSURE;

ADULT; ANALYTIC METHOD; ARTICLE; CHINESE; CONTROLLED STUDY; CORN; DIETARY INTAKE; ENVIRONMENTAL EXPOSURE; FEMALE; FISH; FOOD CONTAMINATION; HAIR ANALYSIS; HEALTH HAZARD; HUMAN; MALE; MINING; PILOT STUDY; PRIORITY JOURNAL; QUALITY CONTROL; QUESTIONNAIRE; RICE; VEGETABLE;

ADULT; ANTIMONY; ARSENIC; CHILD; CHILD, PRESCHOOL; CHINA; DAIRY PRODUCTS; DIET; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FEMALE; FOOD ANALYSIS; FOOD CONTAMINATION; HAIR; HUMANS; INFANT; MALE; MEAT; MIDDLE AGED; MINING; RISK ASSESSMENT; VEGETABLES; WATER SUPPLY;

CHINA; HUNAN; XIKUANGSHAN;

EID: 79959727249     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2011.05.033     Document Type: Article

References (79)

1. Abernathy C., Liu Y., Longfellow D., Aposhian H., Beck B., Fowler B., et al. Arsenic: health effects, mechanisms of actions, and research issues. Environ Health Perspect 1999, 107:593.
2. JECFA (Joint FAO WHO Expert Committee on Food Additives) Evaluation of certain food additives and contaminants. 33rd report, tech rep Ser 776 1989, World Health Organization, Geneva, Switzerland.
3. Ainsworth N., Cooke J., Johnson M. Distribution of antimony in contaminated grassland: 1-Vegetation and soils. Environ Pollut 1990, 65:65-77.
4. Ali M., Tarafdar S. Arsenic in drinking water and in scalp hair by EDXRF: a major recent health hazard in Bangladesh. J Radioanal Nucl Chem 2003, 256:297-305.
5. Amarasiriwardena D., Wu F. Antimony: emerging toxic contaminant in the environment. Microchem J 2011, 97:1-3.
6. Andreae M., Asmode J., Foster P., Van't dack L. Determination of antimony (III), antimony (V), and methylantimony species in natural waters by atomic absorption spectrometry with hydride generation. Anal Chem 1981, 53:1766-1771.
7. Ashley P., Graham B., Tighe M., Wolfenden B. Antimony and arsenic dispersion in the Macleay River catchment, New South Wales: a study of the environmental geochemical consequences. Aust J Earth Sci 2007, 54:83-103.
8. Baroni F., Boscagli A., Protano G., Riccobono F. Antimony accumulation in Achillea ageratum, Plantago lanceolata and Silene vulgaris growing in an old Sb-mining area. Environ Pollut 2000, 109:347-352.
9. Batzevich V.A. Hair trace element analysis in human ecology studies. Sci Total Environ 1995, 164:89-98.
10. BHS (Bureau of Hunan Statistics) Hunan statistical yearbook 2001-2007, (Changsha).
11. Brima E.I., Haris P.I., Jenkins R.O., Polya D.A., Gault A.G., Harrington C.F. Understanding arsenic metabolism through a comparative study of arsenic levels in the urine, hair and fingernails of healthy volunteers from three unexposed ethnic groups in the United Kingdom. Toxicol Appl Pharmacol 2006, 216:122-130.
12. Brown K., Ross G. Arsenic, drinking water, and health: a position paper of the American Council on Science and Health. Regul Toxicol Pharmacol 2002, 36:162-174.
13. Cheung Chung S.W., Kwong K.P., Yau J.C.W., Wong W.W.K. Dietary exposure to antimony, lead and mercury of secondary school students in Hong Kong. Food Addit Contam Part A 2008, 25:831-840.
14. Chinese Ministry of Health. Provisional regulation for defining the arsenic endemic area and for Clinical diagnosis. First national conference proceedings on endemic arsenic poisoning, Hohhot, 1994, pp. Inside back cover [Chinese].
15. Chittleborough G. A chemist's view of the analysis of human hair for trace elements. Sci Total Environ 1980, 14:53-75.
16. Chowdhury U., Biswas B., Chowdhury T., Samanta G., Mandal B., Basu G., et al. Groundwater arsenic contamination in Bangladesh and West Bengal, India. Environ Health Perspect 2000, 108:393-397.
17. EU (European Union) Council directive 76/464/EEC of 4 May 1976 on pollution caused by certain dangerous substances discharged into the aquatic environment of the Community. Official J L 1976, 129:23-29.
18. Dabeka R., McKenzie A., Lacroix G. Dietary intakes of lead, cadmium, arsenic and fluoride by Canadian adults: a 24-hour duplicate diet study. Food Addit Contam 1987, 4:89.
19. De Boeck M., Kirsch-Volders M., Lison D. Cobalt and antimony: genotoxicity and carcinogenicity. Mutat Res Fundam Mol Mech Mutagen 2003, 533:135-152.
20. Feng R., Wei C., Tu S., Wu F., Yang L. Antimony accumulation and antioxidative responses in four fern plants. Plant Soil 2009, 317:93-101.
21. Filella M., Belzile N., Lett M.-C. Antimony in the environment: a review focused on natural waters. III. Microbiota relevant interactions. Earth Sci Rev 2007, 80:195-217.
22. Filella M., Williams P.A., Belzile N. Antimony in the environment: knowns and unknowns. Environ Chem 2009, 6:95-105.
23. Frisbie S., Ortega R., Maynard D., Sarkar B. The concentrations of arsenic and other toxic elements in Bangladesh's drinking water. Environ Health Perspect 2002, 110:1147-1154.
24. FSANZ (Food Standards Australia New Zealand) The 20th Australian total diet survey-a total diet survey of pesticide residues and contaminants. Zealand FSAN 2003, Canberra (Ed.).
25. Fu Z., Wu F., Amarasiriwardena D., Mo C., Liu B., Zhu J., et al. Antimony, arsenic and mercury in the aquatic environment and fish in a large antimony mining area in Hunan, China. Sci Total Environ 2010, 408:3403-3410.
26. Fu Z., Wu F., Mo C., Liu B., Zhu J., Deng Q., et al. Bioaccumulation of antimony, arsenic, and mercury in the vicinities of a large antimony mine, China. Microchem J 2011, 97:12-19.
27. GB5749-2006 (China drinking water standard) Standard for drinking water quality 2007, Standard Publishing House of China, Beijing, [Chinese].
28. Gebel T. Suppression of arsenic-induced chromosome mutagenicity by antimony. Mutat Res Genet Toxicol Environ Mutagen 1998, 412:213-218.
29. Gebel T., Christensen S., Dunkelberg H. Comparative and environmental genotoxicity of antimony and arsenic. Anticancer Res 1997, 17:2603-2607.
30. Gebel T., Claussen K., Dunkelberg H. Human biomonitoring of antimony. Int Arch Occup Environ Health 1998, 71:221-224.
31. Gebel T., Suchenwirth R., Bolten C., Dunkelberg H. Human biomonitoring of arsenic and antimony in case of an elevated geogenic exposure. Environ Health Perspect 1998, 106:33-39.
32. Girgis N., Khayyal M., McConnell E., Norton J. Penicillamine as an adjuvant to antimonial therapy, effect on electrocardiographic changes in dogs. East Afr Med J 1970, 47:576.
33. Groth D., Stettler L., Burg J., Busey W., Grant G., Wong L. Carcinogenic effects of antimony trioxide and antimony ore concentrate in rats. J Toxicol Environ Health 1986, 18:607-626.
34. He M. Distribution and phytoavailability of antimony at an antimony mining and smelting area, Hunan, China. Environ Geochem Health 2007, 29:209-219.
35. He M., Ji H., Zhao C., Xie J., Wu X., Li Z. Preliminary study of heavy metal pollution in soil and plant near antimony mine area. J Beijing Norm Univ Nat Sci Ed 2002, 38:417-420. [Chinese].
36. Herrman J.L., Younes M. Background to the ADI/TDI/PTWI. Regul Toxicol Pharmacol 1999, 30:S109-S113.
37. Hindmarsh J., McCurdy R., Savory J. Clinical and environmental aspects of arsenic toxicity. Crit Rev Clin Lab Sci 1986, 23:315-347.
38. Hinwood A., Sim M., Jolley D., De Klerk N., Bastone E., Gerostamoulos J., et al. Hair and toenail arsenic concentrations of residents living in areas with high environmental arsenic concentrations. Environ Health Perspect 2003, 111:187.
39. IARC (International Agency for Research on Cancer) Antimony trioxide and antimony trisulfide-summaries & evaluation Available, [accessed 15 December 2010]. http://www.inchem.org/documents/iarc/vol47/47-1.html.
40. Jones R. Survey of antimony workers: mortality 1961-1992. Br Med J 1994, 51:772.
41. Krachler M., Zheng J., Koerner R., Zdanowicz C., Fisher D., Shotyk W. Increasing atmospheric antimony contamination in the northern hemisphere: snow and ice evidence from Devon Island, Arctic Canada. J Environ Monitor 2005, 7:1169-1176.
42. Kuroda K., Endo G., Okamoto A., Yoo Y., Horiguchi S. Genotoxicity of beryllium, gallium and antimony in short-term assays. Mutat Res 1991, 264:163.
43. Leblanc J., Guerin T., Noel L., Calamassi-Tran G., volatier J., Verger P. Dietary exposure estimates of 18 elements from the 1st French Total Diet Study. Food Addit Contam Part A 2005, 22:624-641.
44. Lin K., Xu X., Pual A., Xiang Y., Jin X. Relationship between As contents of farmers' hair and of environment in As polluted area. China Environ Sci 2001, 21:440-444. [Chinese].
45. Liu B., Wu F., Deng Q., Mo C., Zhu J., Zeng L., et al. Pollution characteristics of antimony, arsenic and mercury in human hair at Xikuangshan antimony mining area and Guiyang city, China. Environ Sci 2009, 3:907-912. [Chinese].
46. Liu F., Le X., McKnight-Whitford A., Xia Y., Wu F., Elswick E., et al. Antimony speciation and contamination of waters in the Xikuangshan antimony mining and smelting area, China. Environ Geochem Health 2010, 1-13.
47. Mohri T., Hisanaga A., Ishinishi N. Arsenic intake and excretion by Japanese adults: a 7-day duplicate diet study. Food Chem Toxicol 1990, 28:521-529.
48. Pan T., Lin T., Tseng C., Yang M., Huang C. Trace elements in hair of blackfoot disease. Biol Trace Elem Res 1993, 39:117-128.
49. Parris G., Brinckman F. Reactions which relate to environmental mobility of arsenic and antimony. II. Oxidation of trimethylarsine and trimethylstibine. Environ Sci Technol 1976, 10:1128-1134.
50. Poon R., Chu I., Lecavalier P., Valli V., Foster W., Gupta S., et al. Effects of antimony on rats following 90-day exposure via drinking water. Food Chem Toxicol 1998, 36:21-35.
51. Qi C., Wu F., Deng Q., Liu G., Mo C., Liu B., et al. Distribution and accumulation of antimony in plants in the super-large Sb deposit areas, China. Microchem J 2011, 97:44-51.
52. Qi W., Cao J. Background concentration of antimony in Chinese soils. Soil Bull 1991, 22:209-210. [in Chinese].
53. Rahman L., Corns W.T., Bryce D.W., Stockwell P.B. Determination of mercury, selenium, bismuth, arsenic and antimony in human hair by microwave digestion atomic fluorescence spectrometry. Talanta 2000, 52:833-843.
54. Roychowdhury T., Tokunaga H., Ando M. Survey of arsenic and other heavy metals in food composites and drinking water and estimation of dietary intake by the villagers from an arsenic-affected area of West Bengal, India. Sci Total Environ 2003, 308:15-35.
55. SAC (Standardization Administration of the People's Republic of China) Maximum levels of contaminants in foods; GB 2762-2005 2005, [in Chinese].
56. Schnorr T., Steenland K., Thun M., Rinsky R. Mortality in a cohort of antimony smelter workers. Am J Ind Med 2007, 27:759-770.
57. Schoof R., Yost L., Crecelius E., Irgolic K., Goessler W., Guo H.R., et al. Dietary arsenic intake in Taiwanese districts with elevated arsenic in drinking water. Hum Ecol Risk Assess 1998, 4:117-135.
58. Shotyk W., Cheburkin A., Appleby P., Fankhauser A., Kramers J. Two thousand years of atmospheric arsenic, antimony, and lead deposition recorded in an ombrotrophic peat bog profile, Jura Mountains, Switzerland. Earth Planet Sci Lett 1996, 145:1-7.
59. Shotyk W., Krachler M., Chen B. Antimony: global environmental contaminant. J Environ Monit 2005, 7:1135-1136.
60. Shu C. Survey of occupational hazards of population in antimony smelter. Chin Med Fact Mine 2006, 19:282-284. [in Chinese].
61. Tao S., Bolger P. Dietary arsenic intakes in the United States: FDA total diet study, September 1991-December 1996. Food Addit Contam Part A 1999, 16:465-472.
62. Telford K., Maher W., Krikowa F., Foster S., Ellwood M.J., Ashley P.M., et al. Bioaccumulation of antimony and arsenic in a highly contaminated stream adjacent to the Hillgrove Mine, NSW, Australia. Environ Chem 2009, 6:133-143.
63. The Minerals and Metals Sector NRC Antimony. Canadian minerals yearbook 2007.
64. USEPA Water related fate of the 129 priority pollutants, vol. 1 1979, USEPA, Washington, DC, USA.
65. USEPA Special report on ingested inorganic arsenic. Skin cancer, nutritional essentiality (EPA/625/3-87/013) 1988.
66. USEPA Antimony (CASRN 7440-36-0). Integrated risk information system 1991.
67. USGS (U.S.Geological Survey) Mineral commodity summaries; antimony Available, [accessed 15 December 2010]. http://minerals.usgs.gov/minerals/pubs/mcs/.
68. Violante N., Senofonte O., Marsili G., Meli P., Soggiu M.E., Caroli S. Human hair as a marker of pollution by chemical elements emitted by a thermoelectric power plant. Microchem J 2000, 67:397-405.
69. WHO Guidelines for drinking-water quality, third edition, incorporating first and second addenda 2008, World Health Organization, Geneva.
70. Wilson S.C., Lockwood P.V., Ashley P.M., Tighe M. The chemistry and behaviour of antimony in the soil environment with comparisons to arsenic: a critical review. Environ Pollut 2009, 158:1169-1181.
71. Wu F., Zheng J., Pan X., Li W., Deng Q., Mo C., et al. Prospect on biogeochemical cycle and environmental effect of antimony. Adv Earth Sci 2008, 23:350-356. [in Chinese].
72. Yang L., Hou S., Tan J., Lu Y., Wang W., Zhu W., et al. Chinese hair As content background and its regional distribution. Acta Geogr Sin 1996, 51:135-141. [in Chinese].
73. Yang X., Li Y., Ma G., Hu X., Wang J., Cui Z., et al. Study on weight and height of the Chinese people and the differences between 1992 and 2002. Chin J Epidemiol 2005, 26:489-493. [in Chinese].
74. Yost L., Schoof R., Aucoin R. Intake of inorganic arsenic in the North American diet. Hum Ecol Risk Assess 1998, 4:137-152.
75. Ysart G., Miller P., Crews H., Robb P., Baxter M., De L., et al. Dietary exposure estimates of 30 elements from the UK Total Diet Study. Food Addit Contam Part A 1999, 16:391-403.
76. Zhao W., Zhang J. With arsenic contamination of drinking well water by arsenic poisoning caused by the investigation report. Pract Prev Med 1997, 4:36. [in Chinese].
77. Zheng J., Ohata M., Furuta N. Studies on the speciation of inorganic and organic antimony compounds in airborne particulate matter by HPLC-ICP-MS. Analyst 2000, 125:1025-1028.
78. Zhou D., Li S., Deng Q., Xie S., Yuan M. Report of human dermatitis in an antimony smelter. Health Res 1982, 13:55-59. [in Chinese].
79. Zhu J., Wu F., Deng Q., Shao s., Mo C., Pan X., et al. Environmental characteristics of water near the Xikuangshan antimony mine, Hunan Province. Acta Sci Circumst 2009, 29:655-661. [in Chinese].