The Role of the N-Terminal Domain in the Regulation of the "Constitutively Active" Conformation of Protein Kinase CK2α: Insight from a Molecular Dynamics Investigation

ChemMedChem

Volumn 6, Issue 7, 2011, Pages 1207-1216

  Cristiani, Andrea ^a,b   Costa, Giorgio ^b   Cozza, Giorgio ^b   Meggio, Flavio ^b   Scapozza, Leonardo ^a   Moro, Stefano ^b  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

Constitutive activation; Molecular dynamics; N terminal domain; Protein kinase ck2

Indexed keywords

ALANINE; ARGININE; ASPARAGINE; CASEIN KINASE 2ALPHA; CASEIN KINASE II; GLUTAMIC ACID; HISTIDINE; MUTANT PROTEIN; SERINE; TYROSINE; UNCLASSIFIED DRUG; VALINE;

AMINO TERMINAL SEQUENCE; ARTICLE; DELETION MUTANT; ENZYME ACTIVITY; HUMAN; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION;

AMINO ACID SEQUENCE; CASEIN KINASE II; GENE DELETION; HUMANS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, TERTIARY;

EID: 79959694816     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100046     Document Type: Article

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