-
1
-
-
0036828056
-
Excipient-drug interactions in parenteral formulations
-
DOI 10.1002/jps.10154
-
M.J. Akers Excipient-drug interactions in parenteral formulations J. Pharm. Sci. 91 2002 2283 2300 (Pubitemid 35231192)
-
(2002)
Journal of Pharmaceutical Sciences
, vol.91
, Issue.11
, pp. 2283-2300
-
-
Akers, M.J.1
-
2
-
-
19444375866
-
Micelles of methoxy poly(ethylene oxide)-b-poly(ε-caprolactone) as vehicles for the solubilization and controlled delivery of cyclosporine A
-
DOI 10.1016/j.jconrel.2005.02.015, PII S0168365905000829
-
H.M. Aliabadi, A. Mahmud, A.D. Sharifabadi, and A. Lavasanifar Micelles of methoxy poly(ethylene oxide)-b-poly(epsilon-caprolactone) as vehicles for the solubilization and controlled delivery of cyclosporine A J. Control. Release 104 2005 301 311 (Pubitemid 40724931)
-
(2005)
Journal of Controlled Release
, vol.104
, Issue.2
, pp. 301-311
-
-
Aliabadi, H.M.1
Mahmud, A.2
Sharifabadi, A.D.3
Lavasanifar, A.4
-
3
-
-
0020055599
-
Inhibition of T-cell activity by cyclosporin A
-
DOI 10.1111/j.1365-3083.1982.tb00670.x
-
L. Andrus, and K.J. Lafferty Inhibition of T-cell activity by cyclosporin A Scand. J. Immunol. 15 1981 449 458 (Pubitemid 12124743)
-
(1982)
Scandinavian Journal of Immunology
, vol.15
, Issue.5
, pp. 449-458
-
-
Andrus, L.1
Lafferty, K.J.2
-
4
-
-
58149083377
-
Laser fabrication and spectroscopy of organic nanoparticles
-
T. Asahi, T. Sugiyama, and H. Masuhara Laser fabrication and spectroscopy of organic nanoparticles Acc. Chem. Res. 41 2008 1790 1798
-
(2008)
Acc. Chem. Res.
, vol.41
, pp. 1790-1798
-
-
Asahi, T.1
Sugiyama, T.2
Masuhara, H.3
-
5
-
-
0033178415
-
Lab-scale production unit design for nanosuspensions of sparingly soluble cytotoxic drugs
-
DOI 10.1016/S1461-5347(99)00177-7, PII S1461534799001777
-
B.H.L. Böhm, and R.H. Müller Lab-scale production unit design for nanosuspensions of sparingly soluble cytotoxic drugs Pharm. Sci. Technolo. Today 2 1999 336 339 (Pubitemid 29378538)
-
(1999)
Pharmaceutical Science and Technology Today
, vol.2
, Issue.8
, pp. 336-339
-
-
Bohm, B.H.L.1
Muller, R.H.2
-
6
-
-
0021685540
-
Cyclosporine: A new immunosuppressive agent for organ transplantation
-
D.J. Cohen, R. Loertscher, M.F. Rubin, N.L. Tilney, C.B. Carpenter, and T.B. Strom Cyclosporine: a new immunosuppressive agent for organ transplantation Ann. Intern. Med. 101 1984 667 682 (Pubitemid 15223313)
-
(1984)
Annals of Internal Medicine
, vol.101
, Issue.5
, pp. 667-682
-
-
Cohen, D.J.1
Loertscher, R.2
Rubin, M.F.3
-
7
-
-
0037074108
-
The mechanisms of drug release from solid dispersions in water-soluble polymers
-
DOI 10.1016/S0378-5173(01)00891-2, PII S0378517301008912
-
D.Q. Craig The mechanisms of drug release from solid dispersions in water-soluble polymers Int. J. Pharm. 231 2002 131 144 (Pubitemid 34033673)
-
(2002)
International Journal of Pharmaceutics
, vol.231
, Issue.2
, pp. 131-144
-
-
Craig, D.Q.M.1
-
8
-
-
3242673239
-
PH-sensitive nanoparticles for improving the oral bioavailability of cyclosporine a
-
DOI 10.1016/j.ijpharm.2004.05.006, PII S0378517304002893
-
J. Dai, T. Nagai, X. Wang, T. Zhang, M. Meng, and Q. Zhang pH-sensitive nanoparticles for improving the oral bioavailability of cyclosporine A Int. J. Pharm. 280 2004 229 240 (Pubitemid 38950919)
-
(2004)
International Journal of Pharmaceutics
, vol.280
, Issue.1-2
, pp. 229-240
-
-
Dai, J.1
Nagai, T.2
Wang, X.3
Zhang, T.4
Meng, M.5
Zhang, Q.6
-
9
-
-
0035238531
-
Cyclosporin: An updated review of the pharmacokinetic properties, clinical efficacy and tolerability of a microemulsion-based formulation (neoral)1 in organ transplantation
-
C.J. Dunn, A.J. Wagstaff, C.M. Perry, G.L. Plosker, and K.L. Goa Cyclosporin: an updated review of the pharmacokinetic properties, clinical efficacy and tolerability of a microemulsion-based formulation (neoral)1 in organ transplantation Drugs 61 2001 1957 2016
-
(2001)
Drugs
, vol.61
, pp. 1957-2016
-
-
Dunn, C.J.1
Wagstaff, A.J.2
Perry, C.M.3
Plosker, G.L.4
Goa, K.L.5
-
10
-
-
0037027833
-
Positively charged nanoparticles for improving the oral bioavailability of cyclosporin-A
-
DOI 10.1016/S0378-5173(02)00461-1, PII S0378517302004611
-
M.H. El-Shabouri Positively charged nanoparticles for improving the oral bioavailability of cyclosporin-A Int. J. Pharm. 249 2002 101 108 (Pubitemid 35333436)
-
(2002)
International Journal of Pharmaceutics
, vol.249
, Issue.1-2
, pp. 101-108
-
-
El-Shabouri, M.H.1
-
11
-
-
0034880214
-
Cremophor EL: The drawbacks and advantages of vehicle selection for drug formulation
-
DOI 10.1016/S0959-8049(01)00171-X, PII S095980490100171X
-
H. Gelderblom, J. Verweij, K. Nooter, and A. Sparreboom Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation Eur. J. Cancer 37 2001 1590 1598 (Pubitemid 32778603)
-
(2001)
European Journal of Cancer
, vol.37
, Issue.13
, pp. 1590-1598
-
-
Gelderblom, H.1
Verweij, J.2
Nooter, K.3
Sparreboom, A.4
-
12
-
-
0024596954
-
The effect of particle size distribution on dissolution rate and oral absorption
-
DOI 10.1016/0378-5173(89)90069-0
-
R.J. Hintz, and K.C. Johnson The effect of particle size distribution on dissolution rate and oral absorption Int. J. Pharm. 51 1989 9 17 (Pubitemid 19087827)
-
(1989)
International Journal of Pharmaceutics
, vol.51
, Issue.1
, pp. 9-17
-
-
Hintz, R.J.1
Johnson, K.C.2
-
13
-
-
0043023459
-
Nanoparticle formation of poorly water-soluble drugs from ternary ground mixtures with PVP and SDS
-
DOI 10.1248/cpb.51.171
-
K. Itoh, A. Pongpeerapat, Y. Tozuka, T. Oguchi, and K. Yamamoto Nanoparticle formation of poorly water-soluble drugs from ternary ground mixtures with PVP and SDS Chem. Pharm. Bull. (Tokyo) 51 2003 171 174 (Pubitemid 41701987)
-
(2003)
Chemical and Pharmaceutical Bulletin
, vol.51
, Issue.2
, pp. 171-174
-
-
Itoh, K.1
Pongpeerapat, A.2
Tozuka, Y.3
Oguchi, T.4
Yamamoto, K.5
-
14
-
-
77951259002
-
Particle size analysis of nanocrystals: Improved analysis method
-
C.M. Keck Particle size analysis of nanocrystals: improved analysis method Int. J. Pharm. 390 2010 3 12
-
(2010)
Int. J. Pharm.
, vol.390
, pp. 3-12
-
-
Keck, C.M.1
-
15
-
-
5344234787
-
The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs
-
DOI 10.1016/j.ijpharm.2004.07.019, PII S0378517304004582
-
J.E. Kipp The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs Int. J. Pharm. 284 2004 109 122 (Pubitemid 39349144)
-
(2004)
International Journal of Pharmaceutics
, vol.284
, Issue.1-2
, pp. 109-122
-
-
Kipp, J.E.1
-
16
-
-
4344645978
-
Can the pharmaceutical industry reduce attrition rates?
-
I. Kola, and J. Landis Can the pharmaceutical industry reduce attrition rates? Nat. Rev. Drug. Discov. 3 2004 711 715 (Pubitemid 39173511)
-
(2004)
Nature Reviews Drug Discovery
, vol.3
, Issue.8
, pp. 711-715
-
-
Kola, I.1
Landis, J.2
-
17
-
-
0027243792
-
Improved oral absorption of a poorly water-soluble drug, HO-221, by wet-bead milling producing particles in submicron region
-
N. Kondo, T. Iwao, H. Masuda, K. Yamanouchi, Y. Ishihara, N. Yamada, T. Haga, Y. Ogawa, and K. Yokoyama Improved oral absorption of a poorly water-soluble drug HO-221, by wet-bead milling producing particles in submicron region Chem. Pharm. Bull. (Tokyo) 41 1993 737 740 (Pubitemid 23166149)
-
(1993)
Chemical and Pharmaceutical Bulletin
, vol.41
, Issue.4
, pp. 737-740
-
-
Kondo, N.1
Iwao, T.2
Masuda, H.3
Yamanouchi, K.4
Ishihara, Y.5
Yamada, N.6
Haga, T.7
Ogawa, Y.8
Yokoyama, K.9
-
18
-
-
0034461768
-
Drug-like properties and the causes of poor solubility and poor permeability
-
DOI 10.1016/S1056-8719(00)00107-6, PII S1056871900001076
-
C.A. Lipinski Drug-like properties and the causes of poor solubility and poor permeability J. Pharmacol. Toxicol. Methods 44 2000 235 249 (Pubitemid 32239479)
-
(2000)
Journal of Pharmacological and Toxicological Methods
, vol.44
, Issue.1
, pp. 235-249
-
-
Lipinski, C.A.1
-
19
-
-
0022549228
-
Differential effect of cyclosporin A on activation signaling in human T cell lines
-
B. Manger, K.J. Hardy, A. Weiss, and J.D. Stobo Differential effect of cyclosporin A on activation signaling in human T cell lines J. Clin. Invest. 77 1986 1501 1506 (Pubitemid 16047094)
-
(1986)
Journal of Clinical Investigation
, vol.77
, Issue.5
, pp. 1501-1506
-
-
Manger, B.1
Hardy, K.J.2
Weiss, A.3
Stobo, J.D.4
-
20
-
-
0035946615
-
Solid lipid nanoparticles: Production, characterization and applications
-
DOI 10.1016/S0169-409X(01)00105-3, PII S0169409X01001053
-
W. Mehnert, and K. Mäder Solid lipid nanoparticles: production, characterization and applications Adv. Drug. Deliv. Rev. 47 2001 165 196 (Pubitemid 32324113)
-
(2001)
Advanced Drug Delivery Reviews
, vol.47
, Issue.2-3
, pp. 165-196
-
-
Mehnert, W.1
Mader, K.2
-
22
-
-
0032936547
-
Solubility and mass and nuclear magnetic resonance spectroscopic studies on interaction of cyclosporin A with dimethyl-α- and -β-cyclodextrins in aqueous solution
-
DOI 10.1021/js980284+
-
K. Miyake, F. Hirayama, and K. Uekama Solubility and mass and nuclear magnetic resonance spectroscopic studies on interaction of cyclosporin A with dimethyl-alpha- and -beta-cyclodextrins in aqueous solution J. Pharm. Sci. 88 1999 39 45 (Pubitemid 29037366)
-
(1999)
Journal of Pharmaceutical Sciences
, vol.88
, Issue.1
, pp. 39-45
-
-
Miyake, K.1
Hirayama, F.2
Uekama, K.3
-
23
-
-
0028329964
-
Improved dose linearity of cyclosporine pharmacokinetics from a microemulsion formulation
-
DOI 10.1023/A:1018923912135
-
E.A. Mueller, J.M. Kovarik, J.B. van Bree, W. Tetzloff, J. Grevel, and K. Kutz Improved dose linearity of cyclosporine pharmacokinetics from a microemulsion formulation Pharm. Res. 11 1994 301 304 (Pubitemid 24076228)
-
(1994)
Pharmaceutical Research
, vol.11
, Issue.2
, pp. 301-304
-
-
Mueller, E.A.1
Kovarik, J.M.2
Van Bree, J.B.3
Tetzloff, W.4
Grevel, J.5
Kutz, K.6
-
24
-
-
4544275025
-
Challenges and solutions for the delivery of biotech drugs - A review of drug nanocrystal technology and lipid nanoparticles
-
DOI 10.1016/j.jbiotec.2004.06.007, PII S0168165604003128
-
R.H. Muller, and C.M. Keck Challenges and solutions for the delivery of biotech drugs - a review of drug nanocrystal technology and lipid nanoparticles J. Biotechnol. 113 2004 151 170 (Pubitemid 39237077)
-
(2004)
Journal of Biotechnology
, vol.113
, Issue.1-3
, pp. 151-170
-
-
Muller, R.H.1
Keck, C.M.2
-
25
-
-
33744973517
-
®) versus drug nanocrystals
-
DOI 10.1016/j.ijpharm.2006.02.045, PII S037851730600192X
-
R.H. Müller, S. Runge, V. Ravelli, W. Mehnert, A.F. Thunemann, and E.B. Souto Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLN) versus drug nanocrystals Int. J. Pharm. 317 2006 82 89 (Pubitemid 43866342)
-
(2006)
International Journal of Pharmaceutics
, vol.317
, Issue.1
, pp. 82-89
-
-
Muller, R.H.1
Runge, S.2
Ravelli, V.3
Mehnert, W.4
Thunemann, A.F.5
Souto, E.B.6
-
26
-
-
79959690489
-
Indomethacin nanoparticles directly deposited on the fluidized particulate excipient by pulsed laser deposition
-
S. Nagare, and M. Senna Indomethacin nanoparticles directly deposited on the fluidized particulate excipient by pulsed laser deposition J. Nanopart. Res. 8 2004 37 42
-
(2004)
J. Nanopart. Res.
, vol.8
, pp. 37-42
-
-
Nagare, S.1
Senna, M.2
-
27
-
-
79959690948
-
Chemical and structural properties of drug-protein nanocomposites prepared by pulsed laser deposition from conjugated targets
-
S. Nagare, J. Sagawa, and M. Senna Chemical and structural properties of drug-protein nanocomposites prepared by pulsed laser deposition from conjugated targets J. Nanopart. Res. 6 2006 589 593
-
(2006)
J. Nanopart. Res.
, vol.6
, pp. 589-593
-
-
Nagare, S.1
Sagawa, J.2
Senna, M.3
-
28
-
-
34047252848
-
Preparation of glass solutions of three poorly water soluble drugs by spray drying, melt extrusion and ball milling
-
DOI 10.1016/j.ijpharm.2006.11.030, PII S0378517306009781
-
J.E. Patterson, M.B. James, A.H. Forster, R.W. Lancaster, J.M. Butler, and T. Rades Preparation of glass solutions of three poorly water soluble drugs by spray drying, melt extrusion and ball milling Int. J. Pharm. 336 2007 22 34 (Pubitemid 46551551)
-
(2007)
International Journal of Pharmaceutics
, vol.336
, Issue.1
, pp. 22-34
-
-
Patterson, J.E.1
James, M.B.2
Forster, A.H.3
Lancaster, R.W.4
Butler, J.M.5
Rades, T.6
-
29
-
-
0036373887
-
Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the α or β catalytic subunit
-
DOI 10.1046/j.1432-1033.2002.03040.x
-
B.A. Perrino, A.J. Wilson, P. Ellison, and L.H. Clapp Substrate selectivity and sensitivity to inhibition by FK506 and cyclosporin A of calcineurin heterodimers composed of the alpha or beta catalytic subunit Eur. J. Biochem. 269 2002 3540 3548 (Pubitemid 34988998)
-
(2002)
European Journal of Biochemistry
, vol.269
, Issue.14
, pp. 3540-3548
-
-
Perrino, B.A.1
Wilson, A.J.2
Ellison, P.3
Clapp, L.H.4
-
30
-
-
0023947965
-
Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985)
-
R.A. Prentis, Y. Lis, and S.R. Walker Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985) Br. J. Clin. Pharmacol. 25 1988 387 396
-
(1988)
Br. J. Clin. Pharmacol.
, vol.25
, pp. 387-396
-
-
Prentis, R.A.1
Lis, Y.2
Walker, S.R.3
-
31
-
-
33748353240
-
Nanocarriers: Promising vehicle for bioactive drugs
-
DOI 10.1248/bpb.29.1790
-
M. Rawat, D. Singh, S. Saraf, and S. Saraf Nanocarriers: promising vehicle for bioactive drugs Biol. Pharm. Bull. 29 2006 1790 1798 (Pubitemid 44338396)
-
(2006)
Biological and Pharmaceutical Bulletin
, vol.29
, Issue.9
, pp. 1790-1798
-
-
Rawat, M.1
Singh, D.2
Saraf, S.3
Saraf, S.4
-
32
-
-
0032885450
-
Solid dispersion of poorly water-soluble drugs: Early promises, subsequent problems, and recent breakthroughs
-
A.T. Serajuddin Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs J. Pharm. Sci. 88 1999 1058 1066
-
(1999)
J. Pharm. Sci.
, vol.88
, pp. 1058-1066
-
-
Serajuddin, A.T.1
-
33
-
-
0026092821
-
Cyclosporin: Use outside transplantation
-
A.W. Thomson, and G.H. Neild Cyclosporin: use outside transplantation Br. Med. J. 302 1991 4 5
-
(1991)
Br. Med. J.
, vol.302
, pp. 4-5
-
-
Thomson, A.W.1
Neild, G.H.2
-
34
-
-
3042551382
-
Bioavailability and pharmacokinetics of cyclosporine A-loaded pH-sensitive nanoparticles for oral administration
-
DOI 10.1016/j.jconrel.2004.03.003, PII S016836590400121X
-
X.Q. Wang, J.D. Dai, Z. Chen, T. Zhang, G.M. Xia, T. Nagai, and Q. Zhang Bioavailability and pharmacokinetics of cyclosporine A-loaded pH-sensitive nanoparticles for oral administration J. Control. Release 97 2004 421 429 (Pubitemid 38802944)
-
(2004)
Journal of Controlled Release
, vol.97
, Issue.3
, pp. 421-429
-
-
Wang, X.-Q.1
Dai, J.-D.2
Chen, Z.3
Zhang, T.4
Xia, G.-M.5
Nagai, T.6
Zhang, Q.7
-
35
-
-
0035897584
-
Amorphous pharmaceutical solids: Preparation, characterization and stabilization
-
DOI 10.1016/S0169-409X(01)00098-9, PII S0169409X01000989
-
L. Yu Amorphous pharmaceutical solids: preparation, characterization and stabilization Adv. Drug. Deliv. Rev. 48 2001 27 42 (Pubitemid 32454482)
-
(2001)
Advanced Drug Delivery Reviews
, vol.48
, Issue.1
, pp. 27-42
-
-
Yu, L.1
-
36
-
-
53849133761
-
Multi-morphological biodegradable PLGE nanoparticles and their drug release behavior
-
H. Zhang, J. Bei, and S. Wang Multi-morphological biodegradable PLGE nanoparticles and their drug release behavior Biomaterials 30 2009 100 107
-
(2009)
Biomaterials
, vol.30
, pp. 100-107
-
-
Zhang, H.1
Bei, J.2
Wang, S.3
|