Design and performance of an optically accessible, low-volume, mechanobioreactor for long-term study of living constructs

Tissue Engineering - Part C: Methods

Volumn 17, Issue 7, 2011, Pages 775-788

  Paten, Jeffrey A ^a   Zareian, Ramin ^a   Saeidi, Nima ^b   Melotti, Suzanna A ^a   Ruberti, Jeffrey W ^a  

^a Northeastern University   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCONVERSION; BIOREACTORS; FIBROBLASTS; TISSUE;

BIOREACTOR SYSTEM; CELL BEHAVIORS; CELL SHEET; DEAD SPACE; DIFFERENT SUBSTRATES; DYNAMIC IMAGES; FIBROBLAST CULTURES; GROWING TISSUES; IMAGING CAPABILITIES; MECHANICAL LOADS; MECHANICAL STIMULATION; OPTICAL ACCESS; REACTION CHAMBERS; STIMULATED CELLS; TISSUE ENGINEERS; UNIAXIAL TENSILE LOADING;

CELL CULTURE;

COLLAGEN; TISSUE SCAFFOLD;

ANIMAL; ARTICLE; BIOMECHANICS; BIOREACTOR; CATTLE; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; EQUIPMENT DESIGN; FIBROBLAST; HUMAN; INSTRUMENTATION; METHODOLOGY; PHASE CONTRAST MICROSCOPY; TEMPERATURE; TIME; TISSUE ENGINEERING;

ANIMALS; BIOMECHANICS; BIOREACTORS; CATTLE; CELLS, CULTURED; COLLAGEN; EQUIPMENT DESIGN; FIBROBLASTS; HUMANS; MICROSCOPY, INTERFERENCE; TEMPERATURE; TIME FACTORS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 79959691180     PISSN: 19373384     EISSN: 19373392     Source Type: Journal    
DOI: 10.1089/ten.tec.2010.0642     Document Type: Article

References (47)

1. Thompson, D.W. On Growth and Form. Cambridge: Cambridge University Press, 1917.
2. Wolff, J. Das Gesetz Der Transformation Der Knochen. Berlin: A Hirschwald, 1891.
3. Guldberg, R., Butler, D.L., Goldstein, S., Guo, X.E., Kamm, R., Laurencin, C.T., et al. The impact of biomechanics in tissue engineering and regenerative medicine. Tissue Eng Part B Rev 15, 477, 2009.
4. Ingber, D.E. Mechanical control of tissue morphogenesis during embryological development. Int J Dev Biol 50, 255, 2006.
5. Carter, D., and Beaupre, G. Skeletal Form and Function: Mechanobiology of Skeletal Development, Aging and Regeneration. Cambridge: Press Syndicate of the University of Cambridge, 2001.
6. Carter, D.R., Van Der Meulen, M.C., and Beaupre, G.S. Mechanical factors in bone growth and development. Bone 18, 5S, 1996.
7. Chamay, A., and Tschantz, P. Mechanical influences in bone remodeling. Experimental research on Wolff's law. J Biomech 5, 173, 1972.
8. Chalmers, J., and Ray, R. The growth of transplanted foetal bones in different immunological environments. J Bone Joint Surg 44B, 149, 1962.
9. Akeson,W.H.,Amiel, D.,Abel,M.F., Garfin, S.R., andWoo, S.L. Effects of immobilization on joints. Clin Orthop (219), 28, 1987.
10. Henderson, J.H., and Carter, D.R. Mechanical induction in limb morphogenesis: the role of growth-generated strains and pressures. Bone 31, 645, 2002.
11. Altman, G.H., Horan, R.L., Martin, I., Farhadi, J., Stark, P.R., Volloch, V., et al. Cell differentiation by mechanical stress. FASEB J 16, 270, 2002.
12. Arokoski, J.P., Jurvelin, J.S., Vaatainen, U., and Helminen, H.J. Normal and pathological adaptations of articular cartilage to joint loading. Scand J Med Sci Sports 10, 186, 2000.
13. Blain, E.J., Gilbert, S.J., Wardale, R.J., Capper, S.J., Mason, D.J., and Duance, V.C. Up-regulation of matrix metalloproteinase expression and activation following cyclical compressive loading of articular cartilage in vitro. Arch Biochem Biophys 396, 49, 2001.
14. Cowin, S.C. The mechanical and stress adaptive properties of bone. Ann Biomed Eng 11, 263, 1983.
15. Hannafin, J.A., Attia, E.A., Henshaw, R., Warren, R.F., and Bhargava, M.M. Effect of cyclic strain and plating matrix on cell proliferation and integrin expression by ligament fibroblasts. J Orthop Res 24, 149, 2006.
16. He, Y., Macarak, E.J., Korostoff, J.M., and Howard, P.S. Compression and tension: differential effects on matrix accumulation by periodontal ligament fibroblasts in vitro. Connect Tissue Res 45, 28, 2004.
17. Humphrey, J.D. Stress, strain, and mechanotransduction in cells. J Biomech Eng 123, 638, 2001.
18. Parsons, M., Kessler, E., Laurent, G.J., Brown, R.A., and Bishop, J.E. Mechanical load enhances procollagen processing in dermal fibroblasts by regulating levels of procollagen C-proteinase. Exp Cell Res 252, 319, 1999.
19. Petroll, W.M., Vishwanath, M., and Ma, L. Corneal fibroblasts respond rapidly to changes in local mechanical stress. Invest Ophthalmol Vis Sci 45, 3466, 2004.
20. Prajapati, R.T., Chavally-Mis, B., Herbage, D., Eastwood, M., and Brown, R.A. Mechanical loading regulates protease production by fibroblasts in three-dimensional collagen substrates. Wound Repair Regen 8, 226, 2000.
21. Cowin, S.C. How is a tissue built? J Biomech Eng 122, 553, 2000.
22. Cowin, S.C. Tissue growth and remodeling. Annu Rev Biomed Eng 6, 77, 2004.
23. Schulz, R.M., Wustneck, N., van Donkelaar, C.C., Shelton, J.C., and Bader, A. Development and validation of a novel bioreactor system for load- and perfusion-controlled tissue engineering of chondrocyte-constructs. Biotechnol Bioeng 101, 714, 2008.
24. Vunjak-Novakovic, G., Meinel, L., Altman, G., and Kaplan, D. Bioreactor cultivation of osteochondral grafts. Orthod Craniofac Res 8, 209, 2005.
25. Meyer, U., Buchter, A., Nazer, N., and Wiesmann, H.P. Design and performance of a bioreactor system for mechanically promoted three-dimensional tissue engineering. Br J Oral Maxillofac Surg 44, 134, 2006.
26. Demarteau, O., Jakob, M., Schafer, D., Heberer, M., and Martin, I. Development and validation of a bioreactor for physical stimulation of engineered cartilage. Biorheology 40, 331, 2003.
27. Saber, S., Zhang, A.Y., Ki, S.H., Lindsey, D.P., Smith, R.L., Riboh, J., et al. Flexor tendon tissue engineering: bioreactor cyclic strain increases construct strength. Tissue Eng Part A 16, 2085, 2010.
28. Riboh, J., Chong,A.K., Pham,H., Longaker,M., Jacobs, C., and Chang, J. Optimization of flexor tendon tissue engineering with a cyclic strain bioreactor. J Hand Surg Am 33, 1388, 2008.
29. Joshi, S.D., and Webb, K. Variation of cyclic strain parameters regulates development of elastic modulus in fibroblast/ substrate constructs. J Orthop Res 26, 1105, 2008.
30. Feng, Z., Tateishi, Y., Nomura, Y., Kitajima, T., and Nakamura, T. Construction of fibroblast-collagen gels with orientated fibrils induced by static or dynamic stress: toward the fabrication of small tendon grafts. J Artif Organs 9, 220, 2006.
31. Cao, D., Liu, W., Wei, X., Xu, F., Cui, L., and Cao, Y. In vitro tendon engineering with avian tenocytes and polyglycolic acids: a preliminary report. Tissue Eng 12, 1369, 2006.
32. Webb, K., Hitchcock, R.W., Smeal, R.M., Li, W., Gray, S.D., and Tresco, P.A. Cyclic strain increases fibroblast proliferation, matrix accumulation, and elastic modulus of fibroblastseeded polyurethane constructs. J Biomech 39, 1136, 2006.
33. Kall, S., Noth, U., Reimers, K., Choi, C.Y., Muehlberger, T., Allmeling, C., et al. [In vitro fabrication of tendon substitutes using human mesenchymal stem cells and a collagen type I gel]. Handchir Mikrochir Plast Chir 36, 205, 2004.
34. Ellis, M., Jarman-Smith, M., and Chaudhuri, J.B. Bioreactor systems for tissue engineering: A four dimensional challenge. In: Chaudhuri, J.B., and Al-Rubeai, M., Eds. Bioreactors for Tissue Engineering. The Netherlands: Springer, 2005.
35. Portner, R., Nagel-Heyer, S., Goepfert, C., Adamietz, P., and Meenen, N.M. Bioreactor design for tissue engineering. J Biosci Bioeng 100, 235, 2005.
36. Schulz, R.M., and Bader, A. Cartilage tissue engineering and bioreactor systems for the cultivation and stimulation of chondrocytes. Eur Biophys J 36, 539, 2007.
37. Haj, A.J., Hampson, K., and Gogniat, G. Bioreactors for connective tissue engineering: design and monitoring innovations. Adv Biochem Eng Biotechnol 112, 81, 2009.
38. Griffiths, B. Perfusion systems for cell cultivation. Bioprocess Technol 10, 217, 1990.
39. Gooch, K.J., Kwon, J.H., Blunk, T., Langer, R., Freed, L.E., and Vunjak-Novakovic, G. Effects of mixing intensity on tissue-engineered cartilage. Biotechnol Bioeng 72, 402, 2001.
40. Chaudhuri, J., and Al-Rubeai, M. Bioreactors for tissue Engineeering: Principles, Design and Operation. Dordrecht: Springer, 2005.
41. Smith, D.H., Wolf, J.A., and Meaney, D.F. A new strategy to produce sustained growth of central nervous system axons: continuous mechanical tension. Tissue Eng 7, 131, 2001.
42. Sah, R.L., Kim, Y.J., Doong, J.Y., Grodzinsky, A.J., Plaas, A.H., and Sandy, J.D. Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res 7, 619, 1989.
43. Wartella, K.A., and Wayne, J.S. Bioreactor for biaxial mechanical stimulation to tissue engineered constructs. J Biomech Eng 131, 044501, 2009.
44. Juncosa-Melvin, N., Shearn, J.T., Boivin, G.P., Gooch, C., Galloway, M.T., West, J.R., et al. Effects of mechanical stimulation on the biomechanics and histology of stem cellcollagen sponge constructs for rabbit patellar tendon repair. Tissue Eng 12, 2291, 2006.
45. Du, Y., Sundarraj, N., Funderburgh, M.L., Harvey, S.A., Birk, D.E., and Funderburgh, J.L. Secretion and organization of a cornea-like tissue in vitro by stem cells from human corneal stroma. Invest Ophthalmol Vis Sci 48, 5038, 2007.
46. Guo, X., Hutcheon, A.E., Melotti, S.A., Zieske, J.D., Trinkaus- Randall, V., and Ruberti, J.W. Morphologic characterization of organized extracellular matrix deposition by ascorbic acid-stimulated human corneal fibroblasts. Invest Ophthalmol Vis Sci 48, 4050, 2007.
47. Ren, R., Hutcheon, A.E., Guo, X.Q., Saeidi, N., Melotti, S.A., Ruberti, J.W., et al. Human primary corneal fibroblasts synthesize and deposit proteoglycans in long-term 3-D cultures. Dev Dyn 237, 2705, 2008.