Effects of mixing intensity on tissue-engineered cartilage

Biotechnology and Bioengineering

Volumn 72, Issue 4, 2001, Pages 402-407

  Gooch, K J ^a   Kwon, J H ^c   Blunk, T ^b   Langer, R ^c   Freed, L E ^c   Vunjak Novakovic, G ^c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF REGENSBURG   (Germany)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Cartilage; Hydrodynamic forces; Tissue engineering; Turbulent mixing

Indexed keywords

POLYGLYCOLIC ACID;

ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BONE REMODELING; CARTILAGE CELL; CATTLE; COLLAGEN SYNTHESIS; EXTRACELLULAR MATRIX; GENETIC ENGINEERING; HYDRODYNAMICS; MECHANICAL STRESS; NONHUMAN; PROTEIN CONTENT; SHEAR RATE; TURBULENT FLOW;

ANIMALS; ARTIFICIAL ORGANS; BIOPOLYMERS; CARTILAGE, ARTICULAR; CATTLE; CULTURE MEDIA; EXTRACELLULAR MATRIX; GLYCOSAMINOGLYCANS; HYDROGEN-ION CONCENTRATION; ORGAN CULTURE TECHNIQUES; POLYGLYCOLIC ACID; STRESS, MECHANICAL;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0035916374     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0290(20000220)72:4<402::AID-BIT1002>3.0.CO;2-Q     Document Type: Article

References (25)

1. Increasing extracellular matrix production in regenerating cartilage with intermittent physiological pressure
2. Influence of intermittent pressure, fluid flow, and mixing on the regenerative properties of articular chondrocytes
3. Semi-continuous perfusion system for delivering intermittent physiological pressure to regenerating cartilage
4. Physical mechanisms of cell damage in microcarrier cell culture bioreactors
5. Improved quantitation and discrimination of sulphated glycosaminoglycans by the use of dimethylmethylene blue
6. Tissue engineering of cartilage in space
7. Tissue culture bioreactors: Chondrogenesis as a model system
8. Biodegradable polymer scaffolds for tissue engineering
9. Review: Bone tissue engineering: The role of interstitial fluid flow
10. Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay
11. Mechanical regulation of cartilage biosynthetic behavior: Physical stimuli
12. Moderate running exercise augments glycosaminoglycans and thickness of articular cartilage in the knee joint of young beagle dogs
13. Functional arteries grown in vitro
14. Gas exchange is essential for bioreactor cultivation of tissue engineered cartilage
15. Fluid-mechanical damage of animal cells in bioreactors
16. Effects of tissue compression on the hyaluronate-binding properties of newly synthesized proteoglycans in cartilage explants
17. Biosynthetic response of cartilage explants to dynamic compression
18. Control of proteoglycan synthesis. Studies on the activation of synthesis observed during culture of articular cartilages
19. Effects of mixing on the composition and morphology of tissue-engineered cartilage
20. Dynamic seeding of polymer scaffolds for cartilage tissue engineering
21. Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage
22. The determination of hydroxyproline in tissue and protein samples containing small portions of this amino acid
23. Tissue engineering a blood vessel: Regulation of vascular biology by mechanical stresses