메뉴 건너뛰기




Volumn 54, Issue 7, 2011, Pages 1831-1840

The insulin-melatonin antagonism: Studies in the LEW.1AR1-iddm rat (an animal model of human type 1 diabetes mellitus)

Author keywords

AA NAT; Adrenoceptors; Circadian expression; Clock genes Per1 and Bmal1; Glucose; HIOMT; Insulin; Insulin receptor; Melatonin; Type 1 diabetes

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; GLUCOSE; INSULIN; INSULIN RECEPTOR; MELATONIN; PER1 PROTEIN; PROTEIN BMAL1;

EID: 79959689789     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2138-0     Document Type: Article
Times cited : (40)

References (50)
  • 1
    • 0031240984 scopus 로고    scopus 로고
    • Influence of melatonin and serotonin on glucose-stimulated insulin release from perifused rat pancreatic islets in vitro
    • E Peschke D Peschke T Hammer V Csernus 1997 Influence of melatonin and serotonin on glucose-stimulated insulin release from perifused rat pancreatic islets in vitro J Pineal Res 23 156 163 9406987 10.1111/j.1600-079X.1997. tb00349.x 1:CAS:528:DyaK2sXntlyjs7k%3D (Pubitemid 127500008)
    • (1997) Journal of Pineal Research , vol.23 , Issue.3 , pp. 156-163
    • Peschke, E.1    Peschke, D.2    Hammer, T.3    Csemus, V.4
  • 2
    • 0036720357 scopus 로고    scopus 로고
    • 1) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1
    • DOI 10.1034/j.1600-079X.2002.02919.x
    • E Peschke E Muhlbauer U Musshoff VJ Csernus E Chankiewitz D Peschke 2002 Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1 J Pineal Res 33 63 71 12153439 10.1034/j.1600-079X.2002.02919.x 1:CAS:528:DC%2BD38XmsF2ntbo%3D (Pubitemid 34913482)
    • (2002) Journal of Pineal Research , vol.33 , Issue.2 , pp. 63-71
    • Peschke, E.1    Muhlbauer, E.2    Musshoff, U.3    Csernus, V.J.4    Chankiewitz, E.5    Peschke, D.6
  • 3
    • 0036786193 scopus 로고    scopus 로고
    • Melatonin inhibits insulin secretion and decreases PKA levels without interfering with glucose metabolism in rat pancreatic islets
    • 12220330 10.1034/j.1600-079X.2002.02903.x 1:CAS:528:DC%2BD38XntlGitr4%3D
    • MC Picinato EP Haber J Cipolla-Neto R Curi CR de Oliveira Carvalho AR Carpinelli 2002 Melatonin inhibits insulin secretion and decreases PKA levels without interfering with glucose metabolism in rat pancreatic islets J Pineal Res 33 156 160 12220330 10.1034/j.1600-079X.2002.02903.x 1:CAS:528: DC%2BD38XntlGitr4%3D
    • (2002) J Pineal Res , vol.33 , pp. 156-160
    • Picinato, M.C.1    Haber, E.P.2    Cipolla-Neto, J.3    Curi, R.4    De Oliveira Carvalho, C.R.5    Carpinelli, A.R.6
  • 4
    • 0028018966 scopus 로고
    • Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses
    • DOI 10.1016/0896-6273(94)90055-8
    • SM Reppert DR Weaver T Ebisawa 1994 Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses Neuron 13 1177 1185 7946354 10.1016/0896-6273(94)90055-8 1:CAS:528: DyaK2MXitlylsLY%3D (Pubitemid 24372135)
    • (1994) Neuron , vol.13 , Issue.5 , pp. 1177-1185
    • Reppert, S.M.1    Weaver, D.R.2    Ebisawa, T.3
  • 5
    • 0029115639 scopus 로고
    • Molecular characterization of a second melatonin receptor expressed in human retina and brain: The Mel1b melatonin receptor
    • 7568007 10.1073/pnas.92.19.8734 1:CAS:528:DyaK2MXotVGqsrk%3D
    • SM Reppert C Godson CD Mahle DR Weaver SA Slaugenhaupt JF Gusella 1995 Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor Proc Natl Acad Sci USA 92 8734 8738 7568007 10.1073/pnas.92.19.8734 1:CAS:528:DyaK2MXotVGqsrk%3D
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8734-8738
    • Reppert, S.M.1    Godson, C.2    Mahle, C.D.3    Weaver, D.R.4    Slaugenhaupt, S.A.5    Gusella, J.F.6
  • 6
    • 0034071906 scopus 로고    scopus 로고
    • Evidence for a melatonin receptor within pancreatic islets of neonate rats: Functional, autoradiographic, and molecular investigations
    • E Peschke JD Fauteck U Musshoff F Schmidt A Beckmann D Peschke 2000 Evidence for a melatonin receptor within pancreatic islets of neonate rats: functional, autoradiographic, and molecular investigations J Pineal Res 28 156 164 10739302 10.1034/j.1600-079X.2001.280305.x 1:CAS:528:DC%2BD3cXitVyks78%3D (Pubitemid 30162447)
    • (2000) Journal of Pineal Research , vol.28 , Issue.3 , pp. 156-164
    • Peschke, E.1    Fauteck, J.-D.2    Musshoff, U.3    Schmidt, F.4    Beckmann, A.5    Peschke, D.6
  • 7
    • 0037077043 scopus 로고    scopus 로고
    • Identification and functional characterization of melatonin Mel 1a receptors in pancreatic β cells: Potential role in incretin-mediated cell function by sensitization of cAMP signaling
    • DOI 10.1016/S0303-7207(02)00064-3, PII S0303720702000643
    • DM Kemp M Ubeda JF Habener 2002 Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling Mol Cell Endocrinol 191 157 166 12062899 10.1016/S0303-7207(02)00064-3 1:CAS:528:DC%2BD38XksVals7k%3D (Pubitemid 34626621)
    • (2002) Molecular and Cellular Endocrinology , vol.191 , Issue.2 , pp. 157-166
    • Kemp, D.M.1    Ubeda, M.2    Habener, J.F.3
  • 8
    • 36849034462 scopus 로고    scopus 로고
    • Melatonin, endocrine pancreas and diabetes
    • DOI 10.1111/j.1600-079X.2007.00519.x
    • E Peschke 2008 Melatonin, endocrine pancreas and diabetes J Pineal Res 44 26 40 18078445 1:CAS:528:DC%2BD1cXhslGmur8%3D (Pubitemid 350231107)
    • (2008) Journal of Pineal Research , vol.44 , Issue.1 , pp. 26-40
    • Peschke, E.1
  • 9
    • 33845537397 scopus 로고    scopus 로고
    • Evidence for the expression of both the MT1- and in addition, the MT2-melatonin receptor, in the rat pancreas, islet and β-cell
    • DOI 10.1111/j.1600-079X.2006.00399.x
    • E Muhlbauer E Peschke 2007 Evidence for the expression of both the MT1- and in addition, the MT2-melatonin receptor, in the rat pancreas, islet and beta-cell J Pineal Res 42 105 106 17198545 10.1111/j.1600-079X.2006.00399.x 1:CAS:528:DC%2BD2sXhtlKktr4%3D (Pubitemid 44924332)
    • (2007) Journal of Pineal Research , vol.42 , Issue.1 , pp. 105-106
    • Muhlbauer, E.1    Peschke, E.2
  • 10
    • 34147202423 scopus 로고    scopus 로고
    • Melatonin and type 2 diabetes - A possible link?
    • DOI 10.1111/j.1600-079X.2007.00426.x
    • E Peschke I Stumpf I Bazwinsky L Litvak H Dralle E Muhlbauer 2007 Melatonin and type 2 diabetes-a possible link? J Pineal Res 42 350 358 17439551 10.1111/j.1600-079X.2007.00426.x 1:CAS:528:DC%2BD2sXkvFSrt7g%3D (Pubitemid 46581659)
    • (2007) Journal of Pineal Research , vol.42 , Issue.4 , pp. 350-358
    • Peschke, E.1    Stumpf, I.2    Bazwinsky, I.3    Litvak, L.4    Dralle, H.5    Muhlbauer, E.6
  • 12
    • 33645098511 scopus 로고    scopus 로고
    • Parallel signaling pathways of melatonin in the pancreatic beta-cell
    • 16441556 10.1111/j.1600-079X.2005.00297.x 1:CAS:528:DC%2BD28XisFKjtLc%3D
    • E Peschke AG Bach E Muhlbauer 2006 Parallel signaling pathways of melatonin in the pancreatic beta-cell J Pineal Res 40 184 191 16441556 10.1111/j.1600-079X.2005.00297.x 1:CAS:528:DC%2BD28XisFKjtLc%3D
    • (2006) J Pineal Res , vol.40 , pp. 184-191
    • Peschke, E.1    Bach, A.G.2    Muhlbauer, E.3
  • 13
    • 25144453239 scopus 로고    scopus 로고
    • 2+ release from INS1 insulinoma cells
    • DOI 10.1111/j.1600-079X.2005.00253.x
    • AG Bach S Wolgast E Muhlbauer E Peschke 2005 Melatonin stimulates inositol-1,4,5-trisphosphate and Ca2+ release from INS1 insulinoma cells J Pineal Res 39 316 323 16150114 10.1111/j.1600-079X.2005.00253.x 1:CAS:528:DC%2BD2MXhtVKnt7zK (Pubitemid 41337814)
    • (2005) Journal of Pineal Research , vol.39 , Issue.3 , pp. 316-323
    • Bach, A.G.1    Wolgast, S.2    Muhlbauer, E.3    Peschke, E.4
  • 14
    • 51649124759 scopus 로고    scopus 로고
    • Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells
    • 18363673 10.1111/j.1600-079X.2008.00593.x 1:CAS:528:DC%2BD1cXht1eku77M
    • I Stumpf E Muhlbauer E Peschke 2008 Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells J Pineal Res 45 318 327 18363673 10.1111/j.1600-079X.2008.00593.x 1:CAS:528:DC%2BD1cXht1eku77M
    • (2008) J Pineal Res , vol.45 , pp. 318-327
    • Stumpf, I.1    Muhlbauer, E.2    Peschke, E.3
  • 15
    • 59149091752 scopus 로고    scopus 로고
    • Modulation of the cGMP signaling pathway by melatonin in pancreatic beta-cells
    • 19175857 10.1111/j.1600-079X.2008.00638.x 1:CAS:528:DC%2BD1MXit1Gqtbc%3D
    • I Stumpf I Bazwinsky E Peschke 2009 Modulation of the cGMP signaling pathway by melatonin in pancreatic beta-cells J Pineal Res 46 140 147 19175857 10.1111/j.1600-079X.2008.00638.x 1:CAS:528:DC%2BD1MXit1Gqtbc%3D
    • (2009) J Pineal Res , vol.46 , pp. 140-147
    • Stumpf, I.1    Bazwinsky, I.2    Peschke, E.3
  • 16
    • 0024197770 scopus 로고
    • Development of diabetes in the non-obese NIDDM rat (GK rat)
    • 3074659 1:STN:280:DyaL1M3mvF2ksQ%3D%3D
    • Y Goto K Suzuki T Ono M Sasaki T Toyota 1988 Development of diabetes in the non-obese NIDDM rat (GK rat) Adv Exp Med Biol 246 29 31 3074659 1:STN:280:DyaL1M3mvF2ksQ%3D%3D
    • (1988) Adv Exp Med Biol , vol.246 , pp. 29-31
    • Goto, Y.1    Suzuki, K.2    Ono, T.3    Sasaki, M.4    Toyota, T.5
  • 17
    • 33645100557 scopus 로고    scopus 로고
    • Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status
    • 16441550 10.1111/j.1600-079X.2005.00287.x 1:CAS:528:DC%2BD28XisFKjtL0%3D
    • E Peschke T Frese E Chankiewitz, et al. 2006 Diabetic Goto Kakizaki rats as well as type 2 diabetic patients show a decreased diurnal serum melatonin level and an increased pancreatic melatonin-receptor status J Pineal Res 40 135 143 16441550 10.1111/j.1600-079X.2005.00287.x 1:CAS:528:DC%2BD28XisFKjtL0%3D
    • (2006) J Pineal Res , vol.40 , pp. 135-143
    • Peschke, E.1    Frese, T.2    Chankiewitz, E.3
  • 18
    • 70249084876 scopus 로고    scopus 로고
    • Pineal melatonin synthesis is decreased in type 2 diabetic Goto-Kakizaki rats
    • 19695268 10.1016/j.lfs.2009.08.004 1:CAS:528:DC%2BD1MXhtFGks7rN
    • T Frese AG Bach E Muhlbauer, et al. 2009 Pineal melatonin synthesis is decreased in type 2 diabetic Goto-Kakizaki rats Life Sci 85 526 533 19695268 10.1016/j.lfs.2009.08.004 1:CAS:528:DC%2BD1MXhtFGks7rN
    • (2009) Life Sci , vol.85 , pp. 526-533
    • Frese, T.1    Bach, A.G.2    Muhlbauer, E.3
  • 20
    • 77954527245 scopus 로고    scopus 로고
    • Adrenoceptor expression and diurnal rhythms of melatonin and its precursors in the pineal gland of type 2 diabetic Goto-Kakizaki rats
    • 20371702 10.1210/en.2009-1299 1:CAS:528:DC%2BC3cXnsVyqsbk%3D
    • AG Bach E Mühlbauer E Peschke 2010 Adrenoceptor expression and diurnal rhythms of melatonin and its precursors in the pineal gland of type 2 diabetic Goto-Kakizaki rats Endocrinology 151 2483 2493 20371702 10.1210/en.2009-1299 1:CAS:528:DC%2BC3cXnsVyqsbk%3D
    • (2010) Endocrinology , vol.151 , pp. 2483-2493
    • Bach, A.G.1    Mühlbauer, E.2    Peschke, E.3
  • 21
    • 53749104502 scopus 로고    scopus 로고
    • Increased melatonin synthesis in pineal glands of rats in streptozotocin induced type 1 diabetes
    • 18624957 10.1111/j.1600-079X.2008.00612.x 1:CAS:528:DC%2BD1cXhtlKhsr%2FI
    • E Peschke S Wolgast I Bazwinsky K Ponicke E Muhlbauer 2008 Increased melatonin synthesis in pineal glands of rats in streptozotocin induced type 1 diabetes J Pineal Res 45 439 448 18624957 10.1111/j.1600-079X.2008.00612.x 1:CAS:528:DC%2BD1cXhtlKhsr%2FI
    • (2008) J Pineal Res , vol.45 , pp. 439-448
    • Peschke, E.1    Wolgast, S.2    Bazwinsky, I.3    Ponicke, K.4    Muhlbauer, E.5
  • 22
    • 0036164051 scopus 로고    scopus 로고
    • Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of Δ-5 desaturase activity
    • DOI 10.1034/j.1600-079x.2002.10797.x
    • S Nishida T Segawa I Murai S Nakagawa 2002 Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of Delta-5 desaturase activity J Pineal Res 32 26 33 11841597 10.1034/j.1600-079x.2002.10797.x 1:CAS:528:DC%2BD38XhslOrsbo%3D (Pubitemid 34123753)
    • (2002) Journal of Pineal Research , vol.32 , Issue.1 , pp. 26-33
    • Nishida, S.1    Segawa, T.2    Murai, I.3    Nakagawa, S.4
  • 23
    • 27644543541 scopus 로고    scopus 로고
    • Metabolic effects of melatonin on oxidative stress and diabetes mellitus
    • DOI 10.1385/ENDO:27:2:131
    • S Nishida 2005 Metabolic effects of melatonin on oxidative stress and diabetes mellitus Endocrine 27 131 136 16217126 10.1385/ENDO:27:2:131 1:CAS:528:DC%2BD2MXhtFansLnN (Pubitemid 41558445)
    • (2005) Endocrine , vol.27 , Issue.2 , pp. 131-135
    • Nishida, S.1
  • 24
    • 0034465880 scopus 로고    scopus 로고
    • Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat
    • DOI 10.1210/en.141.2.487
    • T Wolden-Hanson DR Mitton RL McCants, et al. 2000 Daily melatonin administration to middle-aged male rats suppresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat Endocrinology 141 487 497 10650927 10.1210/en.141.2.487 1:CAS:528:DC%2BD3cXmvFCnuw%3D%3D (Pubitemid 32250470)
    • (2000) Endocrinology , vol.141 , Issue.2 , pp. 487-497
    • Wolden-Hanson, T.1    Mitton, D.R.2    McCants, R.L.3    Yellon, S.M.4    Wilkinson, C.W.5    Matsumoto, A.M.6    Rasmussen, D.D.7
  • 25
    • 0032962371 scopus 로고    scopus 로고
    • Daily melatonin administration at middle age suppresses male rat visceral fat, plasma leptin, and plasma insulin to youthful levels
    • DOI 10.1210/en.140.2.1009
    • DD Rasmussen BM Boldt CW Wilkinson SM Yellon AM Matsumoto 1999 Daily melatonin administration at middle age suppresses male rat visceral fat, plasma leptin, and plasma insulin to youthful levels Endocrinology 140 1009 1012 9927336 10.1210/en.140.2.1009 1:CAS:528:DyaK1MXntl2luw%3D%3D (Pubitemid 29058243)
    • (1999) Endocrinology , vol.140 , Issue.2 , pp. 1009-1012
    • Rasmussen, D.D.1    Boldt, B.M.2    Wilkinson, C.W.3    Yellon, S.M.4    Matsumoto, A.M.5
  • 26
    • 40049109335 scopus 로고    scopus 로고
    • Prolonged melatonin administration in 6-month-old Sprague-Dawley rats: Metabolic alterations
    • 18389999 10.1556/APhysiol.95.2008.4 1:CAS:528:DC%2BD1cXkt1WgsbY%3D
    • B Bojkova P Orendas L Friedmanova, et al. 2008 Prolonged melatonin administration in 6-month-old Sprague-Dawley rats: metabolic alterations Acta Physiol Hung 95 65 76 18389999 10.1556/APhysiol.95.2008.4 1:CAS:528: DC%2BD1cXkt1WgsbY%3D
    • (2008) Acta Physiol Hung , vol.95 , pp. 65-76
    • Bojkova, B.1    Orendas, P.2    Friedmanova, L.3
  • 27
    • 0035072930 scopus 로고    scopus 로고
    • Influence of melatonin administration on glucose tolerance and insulin sensitivity of postmenopausal women
    • DOI 10.1046/j.1365-2265.2001.01232.x
    • A Cagnacci S Arangino A Renzi, et al. 2001 Influence of melatonin administration on glucose tolerance and insulin sensitivity of postmenopausal women Clin Endocrinol Oxf 54 339 346 11298086 10.1046/j.1365-2265.2001.01232.x 1:CAS:528:DC%2BD3MXjtVCjsbc%3D (Pubitemid 32234198)
    • (2001) Clinical Endocrinology , vol.54 , Issue.3 , pp. 339-346
    • Cagnacci, A.1    Arangino, S.2    Renzi, A.3    Paoletti, A.M.4    Melis, G.B.5    Cagnacci, P.6    Volpe, A.7
  • 28
    • 0242364751 scopus 로고    scopus 로고
    • Effect of pinealectomy on plasma levels of insulin and leptin and on hepatic lipids in type 2 diabetic rats
    • DOI 10.1034/j.1600-079X.2003.00083.x
    • S Nishida R Sato I Murai S Nakagawa 2003 Effect of pinealectomy on plasma levels of insulin and leptin and on hepatic lipids in type 2 diabetic rats J Pineal Res 35 251 256 14521630 10.1034/j.1600-079X.2003.00083.x 1:CAS:528:DC%2BD3sXoslKhsbs%3D (Pubitemid 37338858)
    • (2003) Journal of Pineal Research , vol.35 , Issue.4 , pp. 251-256
    • Nishida, S.1    Sato, R.2    Murai, I.3    Nakagawa, S.4
  • 29
    • 0024498199 scopus 로고
    • Effect of pinealectomy on liver insulin and glucagon receptor concentrations in the rat
    • DOI 10.1111/j.1600-079X.1989.tb00405.x
    • V Rodriguez C Mellado E Alvarez JG de Diego E Blazquez 1989 Effect of pinealectomy on liver insulin and glucagon receptor concentrations in the rat J Pineal Res 6 77 88 2537898 10.1111/j.1600-079X.1989.tb00405.x 1:CAS:528:DyaL1MXhtVyls7Y%3D (Pubitemid 19032489)
    • (1989) Journal of Pineal Research , vol.6 , Issue.1 , pp. 77-88
    • Rodriguez, V.1    Mellado, C.2    Alvarez, E.3    De Diego, J.G.4    Blazquez, E.5
  • 31
    • 1842850630 scopus 로고    scopus 로고
    • Indication of circadian oscillations in the rat pancreas
    • DOI 10.1016/S0014-5793(04)00322-9, PII S0014579304003229
    • E Mühlbauer S Wolgast U Finckh D Peschke E Peschke 2004 Indication of circadian oscillations in the rat pancreas FEBS Lett 564 91 96 15094047 10.1016/S0014-5793(04)00322-9 (Pubitemid 38490705)
    • (2004) FEBS Letters , vol.564 , Issue.1-2 , pp. 91-96
    • Muhlbauer, E.1    Wolgast, S.2    Finckh, U.3    Peschke, D.4    Peschke, E.5
  • 32
    • 0033637383 scopus 로고    scopus 로고
    • Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
    • 11114885 10.1101/gad.183500 1:CAS:528:DC%2BD3cXptVWltrs%3D
    • F Damiola N Le Minh N Preitner B Kornmann F Fleury-Olela U Schibler 2000 Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus Genes Dev 14 2950 2961 11114885 10.1101/gad.183500 1:CAS:528:DC%2BD3cXptVWltrs%3D
    • (2000) Genes Dev , vol.14 , pp. 2950-2961
    • Damiola, F.1    Le Minh, N.2    Preitner, N.3    Kornmann, B.4    Fleury-Olela, F.5    Schibler, U.6
  • 33
    • 67349224047 scopus 로고    scopus 로고
    • Melatonin receptors in pancreatic islets: Good morning to a novel type 2 diabetes gene
    • 19377888 10.1007/s00125-009-1359-y 1:CAS:528:DC%2BD1MXms1yhsrY%3D
    • H Mulder CL Nagorny V Lyssenko L Groop 2009 Melatonin receptors in pancreatic islets: good morning to a novel type 2 diabetes gene Diabetologia 52 1240 1249 19377888 10.1007/s00125-009-1359-y 1:CAS:528:DC%2BD1MXms1yhsrY%3D
    • (2009) Diabetologia , vol.52 , pp. 1240-1249
    • Mulder, H.1    Nagorny, C.L.2    Lyssenko, V.3    Groop, L.4
  • 34
    • 0041877508 scopus 로고    scopus 로고
    • Protective effect of melatonin on β-cell damage in streptozotocin-induced diabetes in rats
    • DOI 10.1078/0065-1281-00711
    • O Yavuz M Cam N Bukan A Guven F Silan 2003 Protective effect of melatonin on beta-cell damage in streptozotocin-induced diabetes in rats Acta Histochem 105 261 266 13677620 10.1078/0065-1281-00711 1:CAS:528:DC%2BD3sXosFahs7Y%3D (Pubitemid 37046259)
    • (2003) Acta Histochemica , vol.105 , Issue.3 , pp. 261-266
    • Yavuz, O.1    Cam, M.2    Bukan, N.3    Guven, A.4    Silan, F.5
  • 35
    • 0020671366 scopus 로고
    • Experimentally-induced diabetes reduces nocturnal pineal melatonin content in the Syrian hamster
    • 6138184 10.1016/0300-9629(83)90314-6 1:STN:280:DyaL2c%2FislGktQ%3D%3D
    • TH Champney GC Brainard BA Richardson RJ Reiter 1983 Experimentally- induced diabetes reduces nocturnal pineal melatonin content in the Syrian hamster Comp Biochem Physiol A Comp Physiol 76 199 201 6138184 10.1016/0300-9629(83)90314-6 1:STN:280:DyaL2c%2FislGktQ%3D%3D
    • (1983) Comp Biochem Physiol A Comp Physiol , vol.76 , pp. 199-201
    • Champney, T.H.1    Brainard, G.C.2    Richardson, B.A.3    Reiter, R.J.4
  • 36
    • 0022646605 scopus 로고
    • Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: Effects of streptozotocin-induced diabetes and insulin injections
    • DOI 10.1016/0300-9629(86)90594-3
    • TH Champney AP Holtorf CM Craft RJ Reiter 1986 Hormonal modulation of pineal melatonin synthesis in rats and Syrian hamsters: effects of streptozotocin-induced diabetes and insulin injections Comp Biochem Physiol A Comp Physiol 83 391 395 2420523 10.1016/0300-9629(86)90594-3 1:STN:280:DyaL287mtlWjtg%3D%3D (Pubitemid 16164252)
    • (1986) Comparative Biochemistry and Physiology - A Physiology , vol.83 , Issue.2 , pp. 391-395
    • Champney, T.H.1    Holtorf, A.P.2    Craft, C.M.3    Reiter, R.J.4
  • 37
    • 34248581860 scopus 로고    scopus 로고
    • Diabetes induces changes in melatonin concentrations in peripheral tissues of rat
    • K Stebelova I Herichova M Zeman 2007 Diabetes induces changes in melatonin concentrations in peripheral tissues of rat Neuro Endocrinol Lett 28 159 165 17435669 1:CAS:528:DC%2BD2sXmtVykt7s%3D (Pubitemid 46744781)
    • (2007) Neuroendocrinology Letters , vol.28 , Issue.2 , pp. 159-165
    • Stebelova, K.1    Herichova, I.2    Zeman, M.3
  • 38
    • 0027391358 scopus 로고
    • Release of catecholamines is increased but does not contribute to the impaired insulin secretion in the perfused pancreata of diabetic rats
    • CG Ostenson P Hjemdahl S Efendic 1993 Release of catecholamines is increased but does not contribute to the impaired insulin secretion in the perfused pancreata of diabetic rats Pancreas 8 34 38 8419906 10.1097/00006676-199301000-00008 1:STN:280:DyaK3s7is1aqtA%3D%3D (Pubitemid 23005574)
    • (1993) Pancreas , vol.8 , Issue.1 , pp. 34-38
    • Ostenson, C.-G.1    Hjemdahl, P.2    Efendic, S.3
  • 39
    • 0026466158 scopus 로고
    • Impaired circadian modulation of sympathovagal activity in diabetes. A possible explanation for altered temporal onset of cardiovascular disease
    • 1423958 1:STN:280:DyaK3s%2FkslSqsg%3D%3D
    • L Bernardi L Ricordi P Lazzari, et al. 1992 Impaired circadian modulation of sympathovagal activity in diabetes. A possible explanation for altered temporal onset of cardiovascular disease Circulation 86 1443 1452 1423958 1:STN:280:DyaK3s%2FkslSqsg%3D%3D
    • (1992) Circulation , vol.86 , pp. 1443-1452
    • Bernardi, L.1    Ricordi, L.2    Lazzari, P.3
  • 40
    • 0032478028 scopus 로고    scopus 로고
    • Effects of streptozotocin-induced diabetes on heart rate, blood pressure and cardiac autonomic nervous control
    • DOI 10.1016/S0165-1838(98)00004-6, PII S0165183898000046
    • KK Hicks E Seifen JR Stimers RH Kennedy 1998 Effects of streptozotocin-induced diabetes on heart rate, blood pressure and cardiac autonomic nervous control J Auton Nerv Syst 69 21 30 9672120 10.1016/S0165-1838(98)00004-6 1:CAS:528:DyaK1cXivVKnsbg%3D (Pubitemid 28270882)
    • (1998) Journal of the Autonomic Nervous System , vol.69 , Issue.1 , pp. 21-30
    • Hicks, K.K.1    Seifen, E.2    Stimers, J.R.3    Kennedy, R.H.4
  • 41
    • 0023913628 scopus 로고
    • Plasma corticosterone, motor activity and metabolic circadian patterns in streptozotocin-induced diabetic rats
    • 3401978 10.3109/07420528809079553 1:CAS:528:DyaL1cXkslWntrg%3D
    • A Velasco I Huerta B Marin 1988 Plasma corticosterone, motor activity and metabolic circadian patterns in streptozotocin-induced diabetic rats Chronobiol Int 5 127 135 3401978 10.3109/07420528809079553 1:CAS:528:DyaL1cXkslWntrg%3D
    • (1988) Chronobiol Int , vol.5 , pp. 127-135
    • Velasco, A.1    Huerta, I.2    Marin, B.3
  • 42
    • 33748145697 scopus 로고    scopus 로고
    • Sexual dimorphism in insulin sensitivity and susceptibility to develop diabetes in rats
    • DOI 10.1677/joe.1.06596
    • P Vital E Larrieta M Hiriart 2006 Sexual dimorphism in insulin sensitivity and susceptibility to develop diabetes in rats J Endocrinol 190 425 432 16899575 10.1677/joe.1.06596 1:CAS:528:DC%2BD28Xpt1Wjtbw%3D (Pubitemid 44307818)
    • (2006) Journal of Endocrinology , vol.190 , Issue.2 , pp. 425-432
    • Vital, P.1    Larrieta, E.2    Hiriart, M.3
  • 43
    • 78349290742 scopus 로고    scopus 로고
    • Long-term enteral administration of melatonin reduces plasma insulin and increases expression of pineal insulin receptors in both Wistar and type 2-diabetic Goto-Kakizaki rats
    • 20840603 10.1111/j.1600-079X.2010.00804.x 1:CAS:528:DC%2BC3cXhsVWgurbJ
    • E Peschke H Schucht E Mühlbauer 2010 Long-term enteral administration of melatonin reduces plasma insulin and increases expression of pineal insulin receptors in both Wistar and type 2-diabetic Goto-Kakizaki rats J Pineal Res 49 373 381 20840603 10.1111/j.1600-079X.2010.00804.x 1:CAS:528:DC%2BC3cXhsVWgurbJ
    • (2010) J Pineal Res , vol.49 , pp. 373-381
    • Peschke, E.1    Schucht, H.2    Mühlbauer, E.3
  • 44
    • 84858497531 scopus 로고    scopus 로고
    • Funktionelle Beziehungen zwischen Melatonin und Insulin- Untersuchungsergebnisse an stoffwechselgesunden und diabetischen Versuchstieren und Patienten
    • Peschke E (ed.) (in German)
    • Peschke E, Mühlbauer E (2007) Funktionelle Beziehungen zwischen Melatonin und Insulin-Untersuchungsergebnisse an stoffwechselgesunden und diabetischen Versuchstieren und Patienten. In: Peschke E (ed.) Endokrinologie III. Vorträge im Rahmen des Projektes 'Zeitstrukturen endokriner Systeme'. Abh Sächs Akad Wiss Leipzig 64:103-118 (in German)
    • (2007) Endokrinologie III. Vorträge im Rahmen des Projektes 'Zeitstrukturen Endokriner Systeme'. Abh Sächs Akad Wiss Leipzig , vol.64 , pp. 103-118
    • Peschke E, M.1
  • 45
    • 0023105456 scopus 로고
    • Adrenal catecholamine metabolism and myocardial adrenergic receptors in streptozotocin diabetic rats
    • DOI 10.1016/0006-2952(87)90407-2
    • MS Bitar M Koulu SI Rapoport M Linnoila 1987 Adrenal catecholamine metabolism and myocardial adrenergic receptors in streptozotocin diabetic rats Biochem Pharmacol 36 1011 1016 2882757 10.1016/0006-2952(87)90407-2 1:CAS:528:DyaL2sXktVGhtrg%3D (Pubitemid 17051089)
    • (1987) Biochemical Pharmacology , vol.36 , Issue.7 , pp. 1011-1016
    • Bitar, M.S.1    Koulu, M.2    Rapoport, S.I.3    Linnoila, M.4
  • 47
    • 77954957492 scopus 로고    scopus 로고
    • Insulin temporal sensitivity and its signaling pathway in the rat pineal gland
    • 20600146 10.1016/j.lfs.2010.06.005 1:CAS:528:DC%2BC3cXptlaktb0%3D
    • RA Peliciari-Garcia AC Marcal JA Silva, et al. 2010 Insulin temporal sensitivity and its signaling pathway in the rat pineal gland Life Sci 87 169 174 20600146 10.1016/j.lfs.2010.06.005 1:CAS:528:DC%2BC3cXptlaktb0%3D
    • (2010) Life Sci , vol.87 , pp. 169-174
    • Peliciari-Garcia, R.A.1    Marcal, A.C.2    Silva, J.A.3
  • 48
    • 0036090807 scopus 로고    scopus 로고
    • Decrease in catechol-O-methyltransferase activity in the liver of streptozotocin-induced diabetic rats
    • DOI 10.1046/j.1440-1681.2002.03673.x
    • JP Wang IM Liu TF Tzeng JT Cheng 2002 Decrease in catechol-O- methyltransferase activity in the liver of streptozotocin-induced diabetic rats Clin Exp Pharmacol Physiol 29 419 422 12010186 10.1046/j.1440-1681.2002.03673.x 1:CAS:528:DC%2BD38XjvFGktrg%3D (Pubitemid 34535363)
    • (2002) Clinical and Experimental Pharmacology and Physiology , vol.29 , Issue.5-6 , pp. 419-422
    • Wang, J.P.1    Liu, I.M.2    Tzeng, T.F.3    Cheng, J.T.4
  • 49
    • 70349577367 scopus 로고    scopus 로고
    • Reducing oxidative/nitrosative stress: A newly-discovered genre for melatonin
    • 19635037 10.1080/10409230903044914 1:CAS:528:DC%2BD1MXptVChs7o%3D
    • RJ Reiter SD Paredes LC Manchester DX Tan 2009 Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin Crit Rev Biochem Mol Biol 44 175 200 19635037 10.1080/10409230903044914 1:CAS:528:DC%2BD1MXptVChs7o%3D
    • (2009) Crit Rev Biochem Mol Biol , vol.44 , pp. 175-200
    • Reiter, R.J.1    Paredes, S.D.2    Manchester, L.C.3    Tan, D.X.4
  • 50
    • 45249089262 scopus 로고    scopus 로고
    • Oxidative stress: The vulnerable β-cell
    • DOI 10.1042/BST0360343
    • S Lenzen 2008 Oxidative stress: the vulnerable beta cell Biochem Soc Trans 36 343 347 18481954 10.1042/BST0360343 1:CAS:528:DC%2BD1cXmtVKlsLo%3D (Pubitemid 351839328)
    • (2008) Biochemical Society Transactions , vol.36 , Issue.3 , pp. 343-347
    • Lenzen, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.