Searching for Major Urinary Proteins (MUPs) as Chemosignals in Urine of Subterranean Rodents

Journal of Chemical Ecology

Volumn 37, Issue 7, 2011, Pages 687-694

  Hagemeyer, Petra ^a   Begall, Sabine ^a   Janotova, Katerina ^b   Todrank, Josephine ^c   Heth, Giora ^c   Jedelsky, Petr L ^b   Burda, Hynek ^a   Stopka, Pavel ^b  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b CHARLES UNIVERSITY   (Czech Republic)

^c UNIVERSITY OF HAIFA   (Israel)

Author keywords

Aphrodisin; Coruro; Fukomys; Lipocalin; Major urinary proteins; Mole rat; Spalacopus; Spalax; Subterranean rodents

Indexed keywords

APHRODISIN PROTEIN, MESOCRICETUS AURATUS; MAJOR URINARY PROTEINS; PHEROMONE; PROTEIN;

CHEMICAL CUE; CHEMICAL ECOLOGY; CHEMORECEPTION; COLONY; CONSPECIFIC; ELECTROKINESIS; EUSOCIALITY; HABITAT STRUCTURE; ODOR; PROTEIN; RODENT; SIGNALING; SUBTERRANEAN ENVIRONMENT; URINE;

ANIMAL; ANIMAL BEHAVIOR; ARTICLE; C57BL MOUSE; CHEMISTRY; COMPARATIVE STUDY; FEMALE; MASS SPECTROMETRY; METABOLISM; MOLE RAT; MOUSE; ODOR; PHYSIOLOGY; RAT; TWO DIMENSIONAL GEL ELECTROPHORESIS; URINE;

ANIMALS; BEHAVIOR, ANIMAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; MICE; MICE, INBRED C57BL; MOLE RATS; ODORS; PHEROMONES; PROTEINS; RATS; SMELL; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; URINE;

COETOMYS ANSELLI; MUS; RATTUS; RODENTIA; SPALACINAE; SPALACOPUS; SPALACOPUS CYANUS; SPALAX;

EID: 79959680050     PISSN: 00980331     EISSN: 15731561     Source Type: Journal    
DOI: 10.1007/s10886-011-9971-y     Document Type: Article

References (38)

1. Begall, S., and Burda, H. 1998. Reproductive characteristics and growth rate in the eusocial Zambian common mole-rat (Cryptomys sp., Bathyergidae). Z. Säugetierk. 63: 297-306.
2. Begall, S., Burda, H., and Gallardo, M. H. 1999. Reproduction, postnatal development and growth of social coruros, Spalacopus cyanus (Octodontidae, Rodentia) from Chile. J. Mammal. 80: 210-217.
3. Beynon, R. J., and Hurst, J. L. 2003. Multiple roles of major urinary proteins in the house mouse, Mus domesticus. Biochem. Soc. Trans. 31: 142-146.
4. Beynon, R. J., and Hurst, J. L. 2004. Urinary proteins and the modulation of chemical scents in mice and rats. Peptides 25: 1553-1563.
5. Beynon, R. J., Veggerby, C., Payne, C., Robertson, D. H. L., Gaskell, S. J., Humphries, R. E., and Hurst, J. L. 2002. Polymorphism in major urinary proteins: Molecular heterogeneity in a wild mouse population. J. Chem. Ecol. 28: 1429-1441.
6. Beynon, R. J., Hurst, J. L., Turton, M. J., Robertson, D. H. L., Armstrong, S. D., Cheetham, S. A., Simpson, D., MacNicoll, A., and Humphries, R. E. 2008. Urinary lipocalins in Rodenta: is there a generic model?, pp. 37-49, in J. L. Hurst, R. J. Beynon, S. C. Roberts, and T. D. Wyatt (eds.). Chemical Signals in Vertebrates 11. Springer, New York.
7. Brown, R. E. and Macdonald, D. W. (eds.). 1985. Social Odours in Mammals. Clarendon Press Oxford.
8. Burda, H., Honeycutt, R. L., Begall, S., Grütjen, O., and Scharff, A. 2000. Are naked and common mole-rats eusocial and if so, why? Behav. Ecol. Sociobiol. 47: 293-303.
9. Cavaggioni, A., and Mucignat-Caretta, C. 2000. Major urinary proteins, alpha(2u)-globulins and aphrodisin. Biochim. Biophys. Acta Protein Struct. Mol. Enzymol. 1482: 218-228.
10. Cheetham, S. A., Thom, M. D., Jury, F., Ollier, W. E. R., Beynon, R. J., and Hurst, J. L. 2007. The genetic basis of individual-recognition signals in the mouse. Current Biology. 17: 1771-1777.
11. Ghiggeri, G. M., Artero, M., Carraro, M., Candiano, G., Musante, L., Bruschi, M., Zennaro, C., Ginevri, F., Caridi, G., Faccini, L., Perfumo, F., and Gusmano, R. 2004. Glomerular albumin permeability as an in vitro model for characterizing the mechanism of focal glomerulosclerosis and predicting post-transplant recurrence. Pediatr. Transplant. 8: 339-343.
12. Hagemeyer, P. 2010. Pheromones in social mole-rats and implications for the mammalian chemical communication. PhD dissertation. University of Duisburg-Essen.
13. Hagemeyer, P. and Begall, S. 2006. Individual odour similarity and discrimination in the coruro (Spalacopus cyanus), Octodontidae. Ethology 112: 529-536.
14. Haim, A., Heth, G., Nevo, E., Gruener, N., and Goldstein, T. (1985). Urine analysis of three rodent species with emphasis on calcium and magnesium bicarbonate. Comp. Biochem. Physiol. 80A: 503-506.
15. Henzel, W. J., Rodriguez, H., Singer, A. G., Stults, J. T., Macrides, F., and Agosta, W. C. 1988. The primary structure of aphrodisin. J. Biol. Chem. 263: 16682-16687.
16. Heth, G. and Todrank, J. 2000. Individual odour similarities across species parallel phylognetic relationships in the S. ehrenbergi superspecies of mole rats. Anim. Behav. 60: 789-795.
17. Heth, G., Nevo, E., and Todrank, J. 1996. Seasonal changes in urinary odors and in responses to them by subterranean mole rats. Physiol. Behav. 60: 963-968.
18. Heth, G., Todrank, J., Begall, S., Wegner, R., and Burda, H. 2004. Genetic relatedness discrimination in a eusocial mole-rat, Cryptomys anselli (Bathyergidae, Rodentia). Folia Zool. 53: 269-278.
19. Humphries, R. E., Robertson, D. H. L., Beynon, R. J., and Hurst, J. L. 1999. Unravelling the chemical basis of competitive scent marking in house mice. Anim. Behav. 58: 1177-1190.
20. Hurst, J. L., Payne, C. E., Nevison, C. M., Marie, A. D., Humphries, R. E., Robertson, D. H. L., Cavaggioni, A., and Beynon, R. J. 2001. Individual recognition in mice mediated by major urinary proteins. Nature 414: 631-634.
21. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
22. Logan, D. W., Marton, T. F., and Stowers, L. 2008. Species specificity in major urinary proteins by parallel evolution. PLoS ONE. 3(9): e3280.
23. Lücke, C., Franzoni, L., Abbate, F., Löhr, F., FerrarI, E., Sorbi, R. T., Rüterjans, H., and Spinsi, A. 1999. Solution structure of recombinant mouse major urinary protein. Eur. J. Biochem. 266: 1210-1218.
24. Martìnez-ricòs, J., Agustìn-Pavòn, C., Lanuza, E., and Martìnez-Garcia, F. 2007. Intraspecific communication through chemical signals in female mice: Reinforcing properties of involatile male sexual pheromones. Chem. Senses 32: 139-148.
25. Mucignat-Caretta, C., Caretta, A., and Cavaggioni, A. 1995. Acceleration of puberty onset in female mice by male urinary proteins. J. Physiol. 486: 517-522.
26. Nevison, C. M., Armstong, S., Beynon, R. J., Humphries, R. E., and Hurst, J. L. 2003. The ownership signature in mouse scent marks is involatile. Proc. Roy. Soc. Lond. B 270: 1957-1963.
27. Nevo, E., Ivanitskaya, E., and Beiles, A. 2001. Adaptive radiation of blind subterranean mole rats: Naming and revisiting the four of the Spalax ehrenbergi superspecies in Israel: Spalax galili (2n = 52), S. golani (2n = 54), S. carmeli (2n = 58), and S. judaei (2n = 60). Backhuys Publishers, Leiden.
28. Novotny, M. V. 2003. Pheromones, binding proteins and receptor responses in rodents. Biochem. Soc. Trans. 31: 117-122.
29. Novotny, M. V., Jemiolo, B., Wiesler, D., MA, W., Harvey, S., Xu, F., Xie, T. M., and Carmack, M. 1999. A unique urinary constituent, 6-hydroxy-6-methyl-3-heptanone, is a pheromone that accelerates puberty in female mice. Chem. Biol. 6: 377-383.
30. Peele, P., Salazar, I., Mimmack, M., Keverne, E. B., and Brennan, P. A. 2003. Low molecular weight constituents of male mouse urine mediate the pregnancy block effect and convey information about the identity of the mating male. Eur. J. Neurosci. 18: 622-628.
31. Robertson, D. H. L., Cox, K. A., Gaskell, S. J., Evershed, R. P., and Beynon, R. J. 1996. Molecular heterogeneity in the major urinary proteins of the house mouse Mus musculus. Biochem. J. 316: 265-272.
32. Robertson, D. H. L., Hurst, J. L., Searle, J. B., Gündüz, I., and Beynon, R. J. 2007. Characterization and comparison of major urinary proteins from the house mouse, Mus musculus domesticus, and the aboriginal mouse, Mus macedonicus. J. Chem. Ecol. 33: 613-630.
33. Rustom, R., Costigan, M., Shenkin, A., and Bone, J. M. 1998. Proteinuria and renal tubular damage: Urinary N-acetyl-beta-D-glucosaminidase and isoenzymes in dissimilar renal disease. Am. J. Nephrol. 18: 179-185.
34. Singer, A., Macrides, F., Clancy, A. N., and Agosta, W. C. 1986. Purification and analysis of a proteinaceous aphrodisiac pheromone from hamster vaginal discharge. J. Biol. Chem. 261: 13323-13326.
35. Singer, A. G., Agosta, W. C., and Clancy, A. N. 1987. The chemistry of vomeronasally detected pheromones: characterization of an aphrodisin protein. Ann. New York Acad. Sci. 519: 287-298.
36. Stopková, R., Zdráhal, Z., Ryba, S., Šedo, O., Šandera, M., and Stopka, P. 2010. Novel OBP genes similar to hamster Aphrodisin in the bank vole, Myodes glareolus. BMC Genomics 11: 45. doi: 10. 1186/1471-2164-11-45.
37. Todrank, J., and Heth, G. 1996. Individual odours in two chromosomal species of blind subterranean mole rats (Spalax ehrenbergi). Conspecific and cross-species discrimination. Ethology 102: 806-811.
38. Todrank, J., and Heth, G. 2003. Odor-genes covariance and genetic relatedness assessments: Rethinking odor-based "recognition" mechanisms in rodents. Adv. Study Behav. 32: 77-130.