Glomerular albumin permeability as an in vitro model for characterizing the mechanism of focal glomerulosclerosis and predicting post-transplant recurrence

Pediatric Transplantation

Volumn 8, Issue 4, 2004, Pages 339-343

  Ghiggeri, Gian Marco ^a   Artero, Mary ^b   Carraro, Michele ^b   Candiano, Giovanni ^a   Musante, Luca ^a   Bruschi, Maurizio ^a   Zennaro, Cristina ^b   Ginevri, Fabrizio ^a   Caridi, Gianluca ^a   Faccini, Luigi ^b   Perfumo, Francesco ^a   Gusmano, Rosanna ^c  

^a G GASLINI INSTITUTE   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c Kidney FUND   (Italy)

Author keywords

Focal segmental glomerulosclerosis; Nephrotic syndrome; Post transplant recurrence; Proteinuria

Indexed keywords

ALBUMIN; APOLIPOPROTEIN E; CLUSTERIN;

CONFERENCE PAPER; FOCAL GLOMERULOSCLEROSIS; HUMAN; IDIOPATHIC DISEASE; IN VITRO STUDY; IN VIVO STUDY; KIDNEY TRANSPLANTATION; PERMEABILITY; POSTOPERATIVE PERIOD; PROTEINURIA; RECURRENCE RISK;

ALBUMINURIA; GLOMERULAR MESANGIUM; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HUMANS; KIDNEY TRANSPLANTATION; MODELS, BIOLOGICAL; PERMEABILITY; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATIONS; RECURRENCE;

EID: 4043164107     PISSN: 13973142     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3046.2004.00178.x     Document Type: Conference Paper

References (29)

1. TIEBOSCH AT, WOLTERS J, FREDERIK PF, et al. Epidemiology of idiopathic glomerular disease: A prospective study. Kidney Int 1987: 32: 112-116.
2. KORBET SM, SCHWARTZ MM, LEWIS EJ. Primary focal segmental glomerulosclerosis: Clinical course and response to therapy. Am J Kidney Dis 1994: 23: 773-783.
3. TEJANI A, NICASTRI AD, SEN D, et al. Long-term evaluation of children with nephrotic syndrome and focal segmental glomerular sclerosis. Nephron 1983: 35: 225-231.
4. ARTERO M, BIAVA C, AMEND W, TOMLANOVICH S, VINCENTI F. Recurrent focal glomerulosclerosis: Natural history and response to therapy. Am J Med 1992: 92: 375-383.
5. INGULLI E, TEJANI A. Incidence, treatment, and outcome of recurrent focal segmental glomerulosclerosis posttransplantation in 42 allografts in children - a single-center experience. Transplantation 1991: 51: 401-405.
6. SENGGUTUVAN P, CAMERON JS, HARTLEY RB, et al. Recurrence of focal segmental glomerulosclerosis in transplanted kidneys: Analysis of incidence and risk factors in 59 allografts. Pediatr Nephrol 1990: 4: 21-28.
7. REA R, SMITH C, SANDHU K, KWAN J, TOMSON C. Successful transplant of a kidney with focal segmental glomerulosclerosis. Nephrol Dial Transplant 2001: 16: 416-417.
8. ARTERO ML, SHARMA R, SAVIN J, VINCENTI F. Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis. Am J Kidney Dis 1994: 23: 574-581.
9. COCHAT P, KASSIR A, COLON S, et al. Recurrent nephrotic syndrome after transplantation: Early treatment with plasmaphaeresis and cyclophosphamide. Pediatr Nephrol 1993: 7: 50-54.
10. DANTAL J, BIGOT E, BOGERS W, et al. Effect of plasma protein adsorption on protein excretion in kidney-transplant recipients with recurrent nephrotic syndrome. N Engl J Med 1994: 330: 7-14.
11. KEMPER MJ, WOLF G, MULLER-WIEFEL DE. Transmission of glomerular permeability factor from a mother to her child. N Engl J Med 2001: 344: 386-387.
12. SAVIN VJ, SHARMA R, LOVELL HB, WELLING DJ. Measurement of albumin reflection coefficient with isolated rat glomeruli. J Am Soc Nephrol 1992: 3: 1260-1269.
13. SAVIN VJ, SHARMA R, SHARMA M, et al. Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis. N Engl J Med 1996: 334: 878-883.
14. DALL'AMICO R, GHIGGERI G, CARRARO M, et al. Prediction and treatment of recurrent focal segmental glomerulosclerosis after renal transplantation in children. Am J Kidney Dis 1999: 34: 1048-1055.
15. SHARMA R, SHARMA M, GE X, MCCARTHY ET, SAVIN VJ. Cyclosporine protects glomeruli from FSGS factor via an increase in glomerular cAMP. Transplantation 1996: 62: 1916-1920.
16. GODFRIN Y, DANTAL J, PERRETTO S, et al. Study of the in vitro effect on glomerular albumin permselectivity of serum before and after renal transplantation in focal segmental glomerulosclerosis. Transplantation 1997: 64: 1711-1715.
17. CARRARO M, CARIDI G, BRUSCHI M, et al. Serum glomerular permeability activity in patients with podocin mutations (NPHS2) and steroid-resistant nephrotic syndrome. J Am Soc Nephrol 2002: 13: 1946-1952.
18. CARIDI G, BERTELLI R, CARREA A, et al. Prevalence, genetics, and clinical features of patients carrying podocin mutations in steroid-resistant nonfamilial focal segmental glomerulosclerosis. J Am Soc Nephrol 2001: 12: 2742-2746.
19. CARIDI G, BERTELLI R, DI DUCA M, et al. Broadening the spectrum of diseases related to podocin mutations. J Am Soc Nephrol 2003: 14: 1278-1286.
20. CATTRAN D, NEOGI T, SHARMA R, MCCARTHY ET, SAVIN VJ. Serial estimates of serum permeability activity and clinical correlates in patients with native kidney focal segmental glomerulosclerosis. J Am Soc Nephrol 2003: 14: 448-453.
21. SHARMA R, SHARMA M, MCCARTHY ET, GE XL, SAVIN VJ. Components of normal serum block the focal segmental glomerulosclerosis factor activity in vitro. Kidney Int 2000: 58: 1973-1979.
22. CANDIANO G, MUSANTE L, CARRARO M, et al. Apolipoproteins prevent glomerular albumin permeability induced in vitro by serum from patients with focal segmental glomerulosclerosis. J Am Soc Nephrol 2001: 12: 143-150.
23. SHARMA M, SHARMA R, MCCARTHY ET, SAVIN VJ. 'The FSGS factor': enrichment and in vivo effect of activity from focal segmental glomerulosclerosis plasma. J Am Soc Nephrol 1999: 10: 552-561.
24. MUSANTE L, CANDIANO G, BRUSCHI M, et al. Characterization of plasma factors that alter the permeability to albumin within isolated glomeruli. Proteomics 2002: 2: 197-205.
25. GHIGGERI GM, CANDIANO G, GINEVRI F, et al. Renal selectivity properties towards endogenous albumin in minimal change nephropathy. Kidney Int 1987: 32: 69-77.
26. GHIGGERI GM, GINEVRI F, CANDIANO G, et al. Characterization of cationic albumin in minimal change nephropathy. Kidney Int 1987: 32: 547-553.
27. GINEVRI F, GHIGGERI GM, CANDIANO G, et al. Endogenous albumin as a marker of renal selectivity in steroid-unresponsive nephrotic syndrome. Nephron 1989: 52: 133-138.
28. DIXON R, BRUNSKILL NJ. Activation of mitogenic pathways by albumin in kidney proximal tubule epithelial cells: Implications for the pathophysiology of proteinuric states. J Am Soc Nephrol 1999: 10: 1487-1497.
29. GHIGGERI GM, BRUSCHI M, CANDIANO G, et al. Depletion of clusterin in renal diseases causing nephrotic syndrome. Kidney Int 2002: 62: 2184-2194.