-
1
-
-
0030748457
-
The insulin signalling system and the IRS proteins
-
DOI 10.1007/s001250051387
-
White MF: The insulin signalling system and the IRS proteins. Diabetologia 1997;40(Suppl 2):S2-S17 (Pubitemid 27306917)
-
(1997)
Diabetologia
, vol.40
, Issue.SUPPL. 2
-
-
White, M.F.1
-
2
-
-
0036400206
-
Genetic variants of insulin receptor substrate-1 (IRS-1) in syndromes of severe insulin resistance. Functional analysis of Ala513Pro and Gly1158Glu IRS-1
-
DOI 10.1046/j.1464-5491.2002.00779.x
-
Berger D, Barroso I, Soos M, Yeo G, Schafer AJ, O'Rahilly S, Whitehead JP: Genetic variants of insulin receptor substrate- 1 (IRS-1) in syndromes of severe insulin resistance. Functional analysis of Ala513Pro and Gly1158Glu IRS-1. Diabet Med 2002;19:804-809 (Pubitemid 35177177)
-
(2002)
Diabetic Medicine
, vol.19
, Issue.10
, pp. 804-809
-
-
Berger, D.1
Barroso, I.2
Soos, M.3
Yeo, G.4
Schafer, A.J.5
O'Rahilly, S.6
Whitehead, J.P.7
-
3
-
-
0027367546
-
Aminoacid polymorphisms of insulin receptor substrate-1 in non-inslin-dependent diabetes mellitus
-
DOI 10.1016/0140-6736(93)92694-O
-
Almind K, Bjorbaek C, Vestergaard H, Hansen T, Echwald S, Pedersen O: Aminoacid polymorphisms of insulin receptor substrate-I in non-insulin-dependent diabetus mellitus. Lancet 1993;342:828-832 (Pubitemid 23285910)
-
(1993)
Lancet
, vol.342
, Issue.8875
, pp. 828-832
-
-
Almind, K.1
Bjorbaek, C.2
Vestergaard, H.3
Hansen, T.4
Echwald, S.5
Pedersen, O.6
-
4
-
-
0030000562
-
Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus
-
DOI 10.1210/jc.81.4.1657
-
Sigal R, Doria A, Warram J, Krolewski A: Codon 92 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of non-insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1996;81:1657-1659 (Pubitemid 26119669)
-
(1996)
Journal of Clinical Endocrinology and Metabolism
, vol.81
, Issue.4
, pp. 1657-1659
-
-
Sigal, R.J.1
Doria, A.2
Warram, J.H.3
Krolewski, A.S.4
-
5
-
-
72049107717
-
Association of Gly972Arg polymorphism of IRS1 gene with type 2 diabetes mellitus in lean participants of a national health survey in Mexico: A candidate gene study
-
Burguete-Garcia AI, Cruz-Lopez M, Madrid-Marina V, Lopez-Ridaura R, Hernández-Avila M, Cortina B, Gomez RE, Velasco-Mondragon E: Association of Gly972Arg polymorphism of IRS1 gene with type 2 diabetes mellitus in lean participants of a national health survey in Mexico: a candidate gene study. Metabolism 2010;59:38-45
-
(2010)
Metabolism
, vol.59
, pp. 38-45
-
-
Burguete-Garcia, A.I.1
Cruz-Lopez, M.2
Madrid-Marina, V.3
Lopez-Ridaura, R.4
Hernández-Avila, M.5
Cortina, B.6
Gomez, R.E.7
Velasco-Mondragon, E.8
-
6
-
-
9244256729
-
Molecular scanning of the insulin receptor substrate-1 (IRS-1) gene in Japanese patients with NIDDM: Identification of five novel polymorphisms
-
DOI 10.1007/s001250050484
-
Ura S, Arald E, Kishikawa H, Shirotani T, Todaka M, Isami S, Shimoda S, Yoshimura R, Matsuda K, Motoyoshi S, Miyamura N, Kahn CR, Shichiri M: Molecular scanning of the insulin receptor substrate-1 (IRS-1) gene in Japanese patients with NIDDM: identification of five novel polymorphisms. Diabetologia 1996;39:600-608 (Pubitemid 26135464)
-
(1996)
Diabetologia
, vol.39
, Issue.5
, pp. 600-608
-
-
Ura, S.1
Araki, E.2
Kishikawa, H.3
Shirotani, T.4
Todaka, M.5
Isami, S.6
Shimoda, S.7
Yoshimura, R.8
Matsuda, K.9
Motoyoshi, S.10
Miyamura, N.11
Kahn, C.R.12
Shichiri, M.13
-
7
-
-
9444289880
-
Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes
-
DOI 10.2337/diabetes.53.12.3313
-
Florez JC, Sjörgen M, Burtt N, Orho-Melander M, Schayer S, Sun M, Almgren P, Lindblad U, Tuomi T, Gaudet D, Hudson TJ, Daly MJ, Ardlie KG, Hirschhorn JN, Altshuler D, Groop L: Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes. Diabetes 2004;53:3313-3318 (Pubitemid 39564509)
-
(2004)
Diabetes
, vol.53
, Issue.12
, pp. 3313-3318
-
-
Florez, J.C.1
Sjogren, M.2
Burtt, N.3
Orho-Melander, M.4
Schayer, S.5
Sun, M.6
Almgren, P.7
Lindblad, U.8
Tuomi, T.9
Gaudet, D.10
Hudson, T.J.11
Daly, M.J.12
Ardlie, K.G.13
Hirschhorn, J.N.14
Altshuler, D.15
Groop, L.16
-
8
-
-
3142759596
-
The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population based studies
-
DOI 10.1111/j.1464-5491.2004.01229.x
-
van Dam RM, Hoebee B, Seidell JC, Schaap MM, Blaak EE, Feskens EJM: The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population-based studies. Diabet Med 2004;21: 752-758 (Pubitemid 38916221)
-
(2004)
Diabetic Medicine
, vol.21
, Issue.7
, pp. 752-758
-
-
Van Dam, R.M.1
Hoebee, B.2
Seidell, J.C.3
Schaap, M.M.4
Blaak, E.E.5
Feskens, E.J.M.6
-
9
-
-
0028912848
-
Insulin receptor substrate-1 gene mutations in NIDDM; Implications for the study of polygenic disease
-
Hitman GA, Hawrami K, McCarthy MI, Viswanathan M, Snehalatha C, Ramachandran A, Tuomilehto J, Tuomilehto- Wolf E, Nissinen A, Pedersen O: Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease. Diabetologia 1995;38:481-486
-
(1995)
Diabetologia
, vol.38
, pp. 481-486
-
-
Hitman, G.A.1
Hawrami, K.2
McCarthy, M.I.3
Viswanathan, M.4
Snehalatha, C.5
Ramachandran, A.6
Tuomilehto, J.7
Tuomilehto- Wolf, E.8
Nissinen, A.9
Pedersen, O.10
-
10
-
-
0034810894
-
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders
-
DOI 10.1096/fj.01-0009rev
-
Sesti G, Federici M, Hribal ML, Lauro D, Sbraccia P, Lauro R: Defects of the insulin receptor substrate (IRS) system in human metabolic disorders. FASEB J 2001;5:2099-2111 (Pubitemid 32927927)
-
(2001)
FASEB Journal
, vol.15
, Issue.12
, pp. 2099-2111
-
-
Sesti, G.1
Federici, M.2
Hribal, M.L.3
Lauro, D.4
Sbraccia, P.5
Lauro, R.6
-
11
-
-
0029118510
-
Insulin resistance: Interactions between obesity and a common variant of insulin receptor substrate-1
-
Clausen JO, Hansen T, Bjorbaek C, Echwald SM, Urhammer SA, Rasmussen S, Andersen CB, Hansen L, Almind K, Pedersen O, Clausen JO, Borch-Johnsen K, Winther K, Haraldsdottir J: Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1. Lancet 1995;346:397-402
-
(1995)
Lancet
, vol.346
, pp. 397-402
-
-
Clausen, J.O.1
Hansen, T.2
Bjorbaek, C.3
Echwald, S.M.4
Urhammer, S.A.5
Rasmussen, S.6
Andersen, C.B.7
Hansen, L.8
Almind, K.9
Pedersen, O.10
Clausen, J.O.11
Borch-Johnsen, K.12
Winther, K.13
Haraldsdottir, J.14
-
12
-
-
0032988612
-
Prevalence of variants in candidate genes for type 2 diabetes mellitus in the Netherlands: The Rotterdam study and the Hoorn study
-
t Hart LM, Stolk RP, Dekker JM, Nijpels G, Grobbee DE, Heine RJ, Maassen JA: Prevalence of variants in candidate genes for type 2 diabetes mellitus in the Netherlands: the Rotterdam study and the Hoorn study. J Clin Endocrinol Metab 1999 84 1002-1006 (Pubitemid 29138233)
-
(1999)
Journal of Clinical Endocrinology and Metabolism
, vol.84
, Issue.3
, pp. 1002-1006
-
-
'T Hart, L.M.1
Stolk, R.P.2
Dekker, J.M.3
Nijpels, G.4
Grobbee, D.E.5
Heine, R.J.6
Maassen, J.A.7
-
13
-
-
34249291282
-
Genetic predisposition of type 2 diabetes among Asian Indians
-
Radha V, Mohan V: Genetic predisposition to type 2 diabetes among Asian Indians. Indian J Med Res 2007;125: 259-274 (Pubitemid 46805447)
-
(2007)
Indian Journal of Medical Research
, vol.125
, Issue.3
, pp. 259-274
-
-
Radha, V.1
Mohan, V.2
-
14
-
-
1242286966
-
The Chennai Urban Rural Epidemiology Study (CURES) - Study design and methodology (Urban Component) (CURES - 1)
-
Deepa M, Pradeepa R, Rema M, Anjana M, Deepa R, Shanthirani S, Mohan V: The Chennai Urban Rural Epidemiology Study (CURES)-study design and Methodology (rrban component) (CURES-1). J Assoc Physicians India 2003;51:863-870 (Pubitemid 41279865)
-
(2003)
Journal of Association of Physicians of India
, vol.51
, Issue.SEP
, pp. 863-870
-
-
Deepa, M.1
Pradeepa, R.2
Rema, M.3
Mohan, A.4
Deepa, R.5
Shanthirani, S.6
Mohan, V.7
-
15
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications
-
Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus, provisional report of a WHO consultation. Diabet Med 1998;15:539-553
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
17
-
-
0015348189
-
Estimation of low density lipoprotein cholesterol without the use of the preparative ultracentrifuge
-
Friedewald WT, Levy RI, Fredrickson DS: Estimation of low density lipoprotein cholesterol without the use of the preparative ultracentrifuge. Clin Chem 1972;18:499-502
-
(1972)
Clin Chem
, vol.18
, pp. 499-502
-
-
Friedewald, W.T.1
Levy, R.I.2
Fredrickson, D.S.3
-
18
-
-
33745440674
-
Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population-not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism
-
Lin T-C, Yen J-M, Gong K-B, Kuo T-C, Ku D-C, Liang S-F, Wu M-J: Abnormal glucose tolerance and insulin resistance in polycystic ovary syndrome amongst the Taiwanese population-not correlated with insulin receptor substrate-1 Gly972Arg/Ala513Pro polymorphism. BMC Med Genet 2006;7:36
-
(2006)
BMC Med Genet
, vol.7
, pp. 36
-
-
Lin, T.-C.1
Yen, J.-M.2
Gong, K.-B.3
Kuo, T.-C.4
Ku, D.-C.5
Liang, S.-F.6
Wu, M.-J.7
-
19
-
-
79959658365
-
Gly972Arg variant in the insulin receptor substrate-1 gene and association with type 2 diabetes, a meta-analysis of 27 studies
-
Jellema A, Zeegers MPA, Feskens EJM, Dagnelie PC, Mensink RP: Gly972Arg variant in the insulin receptor substrate-1 gene and association with type 2 diabetes, a meta-analysis of 27 studies. Diabetologia 2003;30:1063-1070
-
(2003)
Diabetologia
, vol.30
, pp. 1063-1070
-
-
Jellema, A.1
Mpa, Z.2
Ejm, F.3
Dagnelie, P.C.4
Mensink, R.P.5
-
20
-
-
0035084073
-
The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance
-
DOI 10.1007/s001250051628
-
Baroni MG, Arca M, Sentinelli F, Buzzetti R, Capici F, Lovari S, Vitale M, Romeo S, Di Mario U: The G972R variant of the insulin receptor substrate-1 (IRS-1) gene, body fat distribution and insulin resistance. Diabetologia 2001;44:367-372 (Pubitemid 32234465)
-
(2001)
Diabetologia
, vol.44
, Issue.3
, pp. 367-372
-
-
Baroni, M.G.1
Arca, M.2
Sentinelli, F.3
Buzzetti, R.4
Capici, F.5
Lovari, S.6
Vitale, M.7
Romeo, S.8
Di Mario, U.9
-
21
-
-
9444276572
-
Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset
-
DOI 10.2337/diabetes.53.12.3319
-
Zeggini E, Parkinson J, Halford S, Owen KR, Frayling TM, Walker M, Hitman GA, Levy JC, Sampson MJ, Feskens EJ, Hattersley AT, McCarthy MI: Association studies of insulin receptor substrate 1 gene (IRS1) variants in type 2 diabetes samples enriched for family history and early age of onset. Diabetes 2004;53:3319-3322 (Pubitemid 39564510)
-
(2004)
Diabetes
, vol.53
, Issue.12
, pp. 3319-3322
-
-
Zeggini, E.1
Parkinson, J.2
Halford, S.3
Owen, K.R.4
Frayling, T.M.5
Walker, M.6
Hitman, G.A.7
Levy, J.C.8
Sampson, M.J.9
Feskens, E.J.M.10
Hattersley, A.T.11
McCarthy, M.I.12
-
22
-
-
27744503278
-
Molecular scanning for mutations in the insulin receptor substrate-1 (Irs-1) gene in Turkish with type 2 diabetes mellitus
-
DOI 10.1507/endocrj.52.593
-
Orkunogulu Suer FE, Mergen H, Bolu E, Ozata M: Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Turkish population with type 2 diabetes mellitus. Endocrinol J 2005;52:593-598 (Pubitemid 41609049)
-
(2005)
Endocrine Journal
, vol.52
, Issue.5
, pp. 593-598
-
-
Orkunoglu Suer, F.E.1
Mergen, H.2
Bolu, E.3
Ozata, M.4
-
23
-
-
0034351407
-
972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells
-
DOI 10.1210/jc.85.5.2004
-
Hribal ML, Federici M, Porzio O, Lauro D, Borboni P, Accili D, Lauro R, Sesti G: The GlyArg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells. J Clin Endocrinol Metab 2000;85:2004-2013 (Pubitemid 32269313)
-
(2000)
Journal of Clinical Endocrinology and Metabolism
, vol.85
, Issue.5
, pp. 2004-2013
-
-
Hribal, M.L.1
Federici, M.2
Porzio, O.3
Lauro, D.4
Borboni, P.5
Accili, D.6
Lauro, R.7
Sesti, G.8
-
24
-
-
0035078748
-
The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans
-
Stumvoll M, Fritsche A, Volk A, Stefan N, Madaus A, Maerker E, Teigeler A, Koch M, Machicao F, Häring H: The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans. Diabetes 2001;50:882-885 (Pubitemid 32242648)
-
(2001)
Diabetes
, vol.50
, Issue.4
, pp. 882-885
-
-
Stumvoll, M.1
Fritsche, A.2
Volk, A.3
Stefan, N.4
Madaus, A.5
Maerker, E.6
Teigeler, A.7
Koch, M.8
Machicao, F.9
Haring, H.10
-
25
-
-
0036319044
-
972Arg IRS-1 polymorphism
-
Marchetti P, Lupi R, Federici M, Marselli L, Masini M, Boggi U, Del Guerra S, Patane G, Piro S, Anello M, Bergamini E, Purrello F, Lauro R, Mosca F, Sesti G, Del Prato S: Insulin secretory function is impaired in isolated human islets carrying the Gly972Arg IRS-1 polymorphism. Diabetes 2002; 51:1419-1424 (Pubitemid 34826607)
-
(2002)
Diabetes
, vol.51
, Issue.5
, pp. 1419-1424
-
-
Marchetti, P.1
Lupi, R.2
Federici, M.3
Marselll, L.4
Masinl, M.5
Boggl, U.6
Del Guerra, S.7
Patane, G.8
Piro, S.9
Anello, M.10
Bergamini, E.11
Purrello, F.12
Lauro, R.13
Mosca, F.14
Sesti, G.15
Del Prato, S.16
-
26
-
-
14844336893
-
Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation
-
DOI 10.1074/jbc.M412300200
-
McGettrick AJ, Feener EP, Kahn CR: Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation. J Biol Chem 2005;280:6441-6446 (Pubitemid 40341191)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.8
, pp. 6441-6446
-
-
McGettrick, A.J.1
Feener, E.P.2
Kahn, C.R.3
-
27
-
-
0034252531
-
Insulin receptor substrate polymorphisms and type 2 diabetes mellitus
-
Sesti G: Insulin receptor substrate polymorphisms and type 2 diabetes mellitus. Pharmacogenomics 2000;1:343-357
-
(2000)
Pharmacogenomics
, vol.1
, pp. 343-357
-
-
Sesti, G.1
-
28
-
-
0031735456
-
Codon 972 polymorphism of the insulin receptor substrate-1 gene in impaired glucose tolerance and late-onset NIDDM
-
DOI 10.2337/diacare.21.5.753
-
Yamaka K, Yuan X, Ishiyamna S, Shoji S, Kohno S, Koyama K, Koyanagi A, Koyama W, Nonaka K: Codon 972 polymorphism of the insulin receptor substrate-1 gene in impaired glucose tolerance and late-onset NIDDM. Diabetes Care 1998;21:753-756 (Pubitemid 28487067)
-
(1998)
Diabetes Care
, vol.21
, Issue.5
, pp. 753-756
-
-
Yamada, K.1
Yuan, X.2
Ishiyama, S.3
Shoji, S.4
Kohno, S.5
Koyama, K.-I.6
Koyanagi, A.7
Koyama, W.8
Nonaka, K.9
-
29
-
-
0029119117
-
Lack of IRS-1 codon 513 and 972 polymorphism in Pima Indians
-
Celi F, Silver K, Walson J, Knowler W, Bogardus C, Shuldiner A: Lack of IRS-1 codon 513 and 972 polymorphism in Pima Indians. J Clin Endocrinol Metab 1995;80:2827-2829
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 2827-2829
-
-
Celi, F.1
Silver, K.2
Walson, J.3
Knowler, W.4
Bogardus, C.5
Shuldiner, A.6
|