Effects of gastric bypass surgery on insulin resistance and insulin secretion in nondiabetic obese patients

Obesity

Volumn 19, Issue 7, 2011, Pages 1420-1426

  Promintzer Schifferl, Miriam ^a   Prager, Gerhard ^a   Anderwald, Christian ^a   Mandl, Martina ^a   Esterbauer, Harald ^a   Shakeri Leidenmühler, Soheila ^a   Pacini, Giovanni ^b   Stadler, Marietta ^c   Bischof, Martin G ^a   Ludvik, Bernhard ^a   Luger, Aanton ^a   Krebs, Michael ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b CNR   (Italy)

^c Hietzing Hospital   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INSULIN;

ADIPOSE TISSUE; ADULT; AREA UNDER THE CURVE; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HUMAN; HYPERINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LEAN BODY WEIGHT; LIVER PARENCHYMA; MALE; OBESITY; ORAL GLUCOSE TOLERANCE TEST; POSTOPERATIVE PERIOD; POSTPRANDIAL STATE; ROUX Y ANASTOMOSIS; SKELETAL MUSCLE; STOMACH BYPASS;

ADULT; BLOOD GLUCOSE; BODY MASS INDEX; C-REACTIVE PROTEIN; FEMALE; GASTRIC BYPASS; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN RESISTANCE; LIVER; MALE; OBESITY, MORBID; POSTPRANDIAL PERIOD;

EID: 79959662448     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2011.92     Document Type: Article

References (43)

1. Adams TD, Gress RE, Smith SC et al. Long-term mortality after gastric bypass surgery. N Engl J Med 2007;357:753-761. (Pubitemid 47295642)
2. Sjöström L, Narbro K, Sjöström CD et al.; Swedish Obese Subjects Study. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 2007;357:741-752. (Pubitemid 47295641)
3. Balkau B, Shipley M, Jarrett RJ et al. High blood glucose concentration is a risk factor for mortality in middle-aged nondiabetic men. 20-year follow-up in the Whitehall Study, the Paris Prospective Study, and the Helsinki Policemen Study. Diabetes Care 1998;21:360-367. (Pubitemid 28101069)
4. Temelkova-Kurktschiev TS, Koehler C, Henkel E et al. Postchallenge plasma glucose and glycemic spikes are more strongly associated with atherosclerosis than fasting glucose or HbA1c level. Diabetes Care 2000;23:1830-1834.
5. Karabulut A, Iltumur K, Toprak N et al. Insulin response to oral glucose loading and coronary artery disease in nondiabetics. Int Heart J 2005;46:761-770.
6. Buchwald H, Estok R, Fahrbach K et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med 2009;122:248-256.e5.
7. le Roux CW, Welbourn R, Werling M et al. Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass. Ann Surg 2007;246:780-785. (Pubitemid 350035654)
8. Greco AV, Mingrone G, Giancaterini A et al. Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion. Diabetes 2002;51: 144-151. (Pubitemid 34517991)
9. Burstein R, Epstein Y, Charuzi I et al. Glucose utilization in morbidly obese subjects before and after weight loss by gastric bypass operation. Int J Obes Relat Metab Disord 1995;19:558-561.
10. Muscelli E, Mingrone G, Camastra S et al. Differential effect of weight loss on insulin resistance in surgically treated obese patients. Am J Med 2005;118:51-57. (Pubitemid 40082459)
11. Krebs M, Roden M. Nutrient-induced insulin resistance in human skeletal muscle. Curr Med Chem 2004;11:901-908. (Pubitemid 38425922)
12. Cline GW, Magnusson I, Rothman DL et al. Mechanism of impaired insulinstimulated muscle glucose metabolism in subjects with insulin-dependent diabetes mellitus. J Clin Invest 1997;99:2219-2224. (Pubitemid 27203778)
13. ADA. Diagnosis and classification of diabetes mellitus. Diabetes Care 2004; Suppl 1:S5-S10.
14. Hother-Nielsen O, Henriksen JE, Holst JJ, Beck-Nielsen H. Effects of insulin on glucose turnover rates in vivo: isotope dilution versus constant specific activity technique. Metabolism 1996;45:82-91. (Pubitemid 26104272)
15. Krebs M, Krssak M, Nowotny P et al. Free fatty acids inhibit the glucosestimulated increase of intramuscular glucose-6-phosphate concentration in humans. J Clin Endocrinol Metab 2001;86:2153-2160. (Pubitemid 32472933)
16. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979;237: E214-E223. (Pubitemid 9249478)
17. Anderwald C, Bernroider E, Krssak M et al. Effects of insulin treatment in type 2 diabetic patients on intracellular lipid content in liver and skeletal muscle. Diabetes 2002;51:3025-3032.
18. Gastaldelli A, Miyazaki Y, Pettiti M et al. Separate contribution of diabetes, total fat mass, and fat topography to glucose production, gluconeogenesis, and glycogenolysis. J Clin Endocrinol Metab 2004;89:3914-3921. (Pubitemid 39071494)
19. Stadler M, Anderwald C, Karer T et al. Increased plasma amylin in type 1 diabetic patients after kidney and pancreas transplantation: A sign of impaired beta-cell function? Diabetes Care 2006;29:1031-1038. (Pubitemid 44115240)
20. Wallace TM, Matthews DR. The assessment of insulin resistance in man. Diabet Med 2002;19:527-534. (Pubitemid 35300672)
21. Ahrén B, Pacini G. Impaired adaptation of first-phase insulin secretion in postmenopausal women with glucose intolerance. Am J Physiol 1997;273:E701-E707.
22. Bikman BT, Zheng D, Pories WJ et al. Mechanism for improved insulin sensitivity after gastric bypass surgery. J Clin Endocrinol Metab 2008;93:4656-4663.
23. Duckworth WC. Insulin degradation: mechanisms, products, and significance. Endocr Rev 1988;9:319-345.
24. Valera Mora ME, Scarfone A, Calvani M, Greco AV, Mingrone G. Insulin clearance in obesity. J Am Coll Nutr 2003;22:487-493. (Pubitemid 38010014)
25. Jimenez J, Zuniga-Guajardo S, Zinman B, Angel A. Effects of weight loss in massive obesity on insulin and C-peptide dynamics: sequential changes in insulin production, clearance, and sensitivity. J Clin Endocrinol Metab 1987;64:661-668. (Pubitemid 17044529)
26. Letiexhe MR, Scheen AJ, Gérard PL, Desaive C, Lefèbvre PJ. Insulin secretion, clearance and action before and after gastroplasty in severely obese subjects. Int J Obes Relat Metab Disord 1994;18:295-300. (Pubitemid 24140807)
27. Patti ME, McMahon G, Mun EC et al. Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia. Diabetologia 2005;48: 2236-2240. (Pubitemid 41618912)
28. Meier JJ, Butler AE, Galasso R, Butler PC. Hyperinsulinemic hypoglycemia after gastric bypass surgery is not accompanied by islet hyperplasia or increased beta-cell turnover. Diabetes Care 2006;29:1554-1559. (Pubitemid 44127580)
29. Norman JT, Bohman RE, Fischmann G et al. Patterns of mRNA expression during early cell growth differ in kidney epithelial cells destined to undergo compensatory hypertrophy versus regenerative hyperplasia. Proc Natl Acad Sci USA 1988;85:6768-6772.
30. Studer H, Derwahl M. Mechanisms of nonneoplastic endocrine hyperplasia-a changing concept: a review focused on the thyroid gland. Endocr Rev 1995;16:411-426.
31. Manfredini G, Ermini M, Scopsi L, Bonaguidi F, Ferrannini E. Internal biliary diversion improves glucose tolerance in the rat. Am J Physiol 1985;249:G519-G527. (Pubitemid 16201180)
32. Strader AD, Vahl TP, Jandacek RJ et al. Weight loss through ileal transposition is accompanied by increased ileal hormone secretion and synthesis in rats. Am J Physiol Endocrinol Metab 2005;288:E447-E453. (Pubitemid 40110655)
33. Toft-Nielsen M, Madsbad S, Holst JJ. Exaggerated secretion of glucagonlike peptide-1 (GLP-1) could cause reactive hypoglycaemia. Diabetologia 1998;41:1180-1186. (Pubitemid 28449084)
34. Service GJ, Thompson GB, Service FJ et al. Hyperinsulinemic hypoglycemia with nesidioblastosis after gastric-bypass surgery. N Engl J Med 2005;353:249-254. (Pubitemid 41058324)
35. Abdul-Ghani MA, Matsuda M, DeFronzo RA. Strong association between insulin resistance in liver and skeletal muscle in non-diabetic subjects. Diabet Med 2008;25:1289-1294.
36. Isbell JM, Tamboli RA, Hansen EN et al. The importance of caloric restriction in the early improvements in insulin sensitivity after Roux-en-Y gastric bypass surgery. Diabetes Care 2010;33:1438-1442.
37. Lima MM, Pareja JC, Alegre SM et al. Acute effect of roux-en-y gastric bypass on whole-body insulin sensitivity: a study with the euglycemichyperinsulinemic clamp. J Clin Endocrinol Metab 2010;95:3871-3875.
38. Petersen KF, Dufour S, Befroy D et al. Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes. Diabetes 2005;54:603-608. (Pubitemid 40322060)
39. Shulman GI, Rothman DL, Jue T et al. Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med 1990;322:223-228. (Pubitemid 20034509)
40. Guidone C, Manco M, Valera-Mora E et al. Mechanisms of recovery from type 2 diabetes after malabsorptive bariatric surgery. Diabetes 2006;55:2025-2031. (Pubitemid 44509976)
41. Camastra S, Manco M, Mari A et al. beta-cell function in morbidly obese subjects during free living: long-term effects of weight loss. Diabetes 2005;54:2382-2389. (Pubitemid 41134266)
42. Schenk S, Saberi M, Olefsky JM. Insulin sensitivity: modulation by nutrients and inflammation. J Clin Invest 2008;118:2992-3002.
43. Salinari S, Bertuzzi A, Iaconelli A, Manco M, Mingrone G. Twenty-four hour insulin secretion and beta cell NEFA oxidation in type 2 diabetic, morbidly obese patients before and after bariatric surgery. Diabetologia 2008;51:1276-1284.