Bladder cancer and cancer stem cells: Basic science and implications for therapy

TheScientificWorldJournal

Volumn 11, Issue , 2011, Pages 1187-1194

  Bryan, Richard T ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Bladder cancer; Cancer stem cells; Stem cells

Indexed keywords

CETUXIMAB;

BLADDER CANCER; CANCER CENTER; CANCER GROWTH; CANCER RECURRENCE; CANCER RESISTANCE; CANCER RISK; CANCER STAGING; CANCER STEM CELL; CANCER SURVIVAL; CELL THERAPY; HUMAN; PATHOGENESIS; REVIEW; STEM CELL; SURVIVAL RATE; TRANSITIONAL CELL CARCINOMA; UROGENITAL TRACT TUMOR;

BIOLOGICAL MARKERS; HUMANS; NEOPLASM INVASIVENESS; NEOPLASTIC STEM CELLS; SIGNAL TRANSDUCTION; URINARY BLADDER; URINARY BLADDER NEOPLASMS;

EID: 79959633859     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/tsw.2011.117     Document Type: Review

References (54)

1. van Rhijn, B.W., Burger, M., Lotan, Y., Solsona, E., Stief, C.G., Sylvester, R.J., et al. (2009) Recurrence and progression of disease in non-muscle-invasive bladder cancer: from epidemiology to treatment strategy. Eur. Urol. 56(3), 430-442.
2. Ploeg, M., Aben, K.K., and Kiemeney, L.A. (2009) The present and future burden of urinary bladder cancer in the world. World J. Urol. 27(3), 289-293.
3. (2009) CancerStats Key Facts - Bladder Cancer. Cancer Research UK.
4. Wallace, D.M., Bryan, R.T., Dunn, J.A., Begum, G., and Bathers, S. (2002) Delay and survival in bladder cancer. BJU Int. 89(9), 868-878. (Pubitemid 34535418)
5. Oosterlinck, W., Lobel, B., Jakse, G., Malmstrom, P.U., Stockle, M., and Sternberg, C. (2002) Guidelines on bladder cancer. Eur. Urol. 41(2), 105-112.
6. Lorusso, V. and Silvestris, N. (2005) Systemic chemotherapy for patients with advanced and metastatic bladder cancer: current status and future directions. Ann. Oncol. 16(Suppl 4), iv85-iv89.
7. Chan, K.S., Volkmer, J.P., and Weissman, I. (2010) Cancer stem cells in bladder cancer: a revisited and evolving concept. Curr. Opin. Urol. 20(5), 393-397.
8. Advanced Bladder Cancer (ABC) Meta-analysis Collaboration (2005) Neoadjuvant chemotherapy in invasive bladder cancer: update of a systematic review and meta-analysis of individual patient data advanced bladder cancer (ABC) meta-analysis collaboration. Eur. Urol. 48(2), 202-205.
9. Castillo-Martin, M., Domingo-Domenech, J., Karni-Schmidt, O., Matos, T., and Cordon-Cardo, C. (2010) Molecular pathways of urothelial development and bladder tumorigenesis. Urol. Oncol. 28(4), 401-408.
10. Cooperberg, M.R., Porter, M.P., and Konety, B.R. (2009) Candidate quality of care indicators for localized bladder cancer. Urol. Oncol. 27(4), 435-442.
11. Donat, S.M., Shabsigh, A., Savage, C., Cronin, A.M., Bochner, B.H., Dalbagni, G., et al. (2009) Potential impact of postoperative early complications on the timing of adjuvant chemotherapy in patients undergoing radical cystectomy: a high-volume tertiary cancer center experience. Eur. Urol. 55(1), 177-185.
12. Kaufman, D.S. (2006) Challenges in the treatment of bladder cancer. Ann. Oncol. 17(Suppl 5), v106-v112.
13. Moltzahn, F.R., Volkmer, J.P., Rottke, D., and Ackermann, R. (2008) "Cancer stem cells"-lessons from Hercules to fight the Hydra. Urol. Oncol. 26(6), 581-589.
14. Shabsigh, A., Korets, R., Vora, K.C., Brook, C.M., Cronin, A.M., Savage, C., et al. (2009) Defining early morbidity of radical cystectomy for patients with bladder cancer using a standardized reporting methodology. Eur. Urol. 55(1), 164-174.
15. Mani, S.A., Guo, W., Liao, M.J., Eaton, E.N., Ayyanan, A., Zhou, A.Y., et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133(4), 704-715. (Pubitemid 351636299)
16. McConkey, D.J., Lee, S., Choi, W., Tran, M., Majewski, T., Lee, S., et al. (2010) Molecular genetics of bladder cancer: emerging mechanisms of tumor initiation and progression. Urol. Oncol. 28(4), 429-440.
17. Ben-Porath, I., Thomson, M.W., Carey, V.J., Ge, R., Bell, G.W., Regev, A., et al. (2008) An embryonic stem celllike gene expression signature in poorly differentiated aggressive human tumors. Nat. Genet. 40(5), 499-507.
18. Chan, K.S., Espinosa, I., Chao, M., Wong, D., Ailles, L., Diehn, M., et al. (2009) Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc. Natl. Acad. Sci. U. S. A. 106(33), 14016-14021.
19. Reya, T., Morrison, S.J., Clarke, M.F., and Weissman, I.L. (2001) Stem cells, cancer, and cancer stem cells. Nature 414(6859), 105-111. (Pubitemid 33041634)
20. Hanahan, D. and Weinberg, R.A. (2011) Hallmarks of cancer: the next generation. Cell 144(5), 646-674.
21. Brandt, W.D., Matsui, W., Rosenberg, J.E., He, X., Ling, S., Schaeffer, E.M., et al. (2009) Urothelial carcinoma: stem cells on the edge. Cancer Metastasis Rev. 28(3-4), 291-304.
22. Bryan, R.T., Hussain, S.A., James, N.D., Jankowski, J.A., and Wallace, D.M. (2005) Molecular pathways in bladder cancer: part 2. BJU Int. 95(4), 491-496. (Pubitemid 40311457)
23. Bryan, R.T., Hussain, S.A., James, N.D., Jankowski, J.A., and Wallace, D.M. (2005) Molecular pathways in bladder cancer: part 1. BJU Int. 95(4), 485-490. (Pubitemid 40311456)
24. Hanahan, D. and Weinberg, R.A. (2000) The hallmarks of cancer. Cell 100(1), 57-70. (Pubitemid 30046295)
25. Goebell, P.J. and Knowles, M.A. (2010) Bladder cancer or bladder cancers? Genetically distinct malignant conditions of the urothelium. Urol. Oncol. 28(4), 409-428.
26. Rosen, J.M. and Jordan, C.T. (2009) The increasing complexity of the cancer stem cell paradigm. Science 324(5935), 1670-1673.
27. Visvader, J.E. and Lindeman, G.J. (2008) Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat. Rev. Cancer 8(10), 755-768.
28. Chiang, A.C. and Massague, J. (2008) Molecular basis of metastasis. N. Engl. J. Med. 359(26), 2814-2823.
29. Gupta, P.B., Chaffer, C.L., and Weinberg, R.A. (2009) Cancer stem cells: mirage or reality? Nat. Med. 15(9), 1010-1012.
30. Clarke, M.F., Dick, J.E., Dirks, P.B., Eaves, C.J., Jamieson, C.H., Jones, D.L., et al. (2006) Cancer stem cells - perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res. 66(19), 9339-9344. (Pubitemid 44623625)
31. Hoglund, M. (2007) On the origin of syn- and metachronous urothelial carcinomas. Eur. Urol. 51(5), 1185-1193.
32. Kurzrock, E.A., Lieu, D.K., Degraffenried, L.A., Chan, C.W., and Isseroff, R.R. (2008) Label-retaining cells of the bladder: candidate urothelial stem cells. Am. J. Physiol. Renal Physiol. 294(6), F1415-F1421.
33. Bryan, R.T. and Tselepis, C. (2010) Cadherin switching and bladder cancer. J. Urol. 184(2), 423-431.
34. Signoretti, S., Pires, M.M., Lindauer, M., Horner, J.W., Grisanzio, C., Dhar, S., et al. (2005) p63 regulates commitment to the prostate cell lineage. Proc. Natl. Acad. Sci. U. S. A. 102(32), 11355-11360.
35. Nguyen, M.M., Lieu, D.K., Degraffenried, L.A., Isseroff, R.R., and Kurzrock, E.A. (2007) Urothelial progenitor cells: regional differences in the rat bladder. Cell Prolif. 40(2), 157-165. (Pubitemid 46398813)
36. Thangappan, R. and Kurzrock, E.A. (2009) Three clonal types of urothelium with different capacities for replication. Cell Prolif. 42(6), 770-779.
37. Barker, N., van Es, J.H., Kuipers, J., Kujala, P., van den Born, M., Cozijnsen, M., et al. (2007) Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449(7165), 1003-1007. (Pubitemid 350014593)
38. He, X., Marchionni, L., Hansel, D.E., Yu, W., Sood, A., Yang, J., et al. (2009) Differentiation of a highly tumorigenic basal cell compartment in urothelial carcinoma. Stem Cells 27(7), 1487-1495.
39. Nusse, R. (2008) Wnt signaling and stem cell control. Cell Res. 18(5), 523-527.
40. Chang, C.C., Shieh, G.S., Wu, P., Lin, C.C., Shiau, A.L., and Wu, C.L. (2008) Oct-3/4 expression reflects tumor progression and regulates motility of bladder cancer cells. Cancer Res. 68(15), 6281-6291.
41. Yang, Y.M. and Chang, J.W. (2008) Bladder cancer initiating cells (BCICs) are among EMA-CD44v6+ subset: novel methods for isolating undetermined cancer stem (initiating) cells. Cancer Invest. 26(7), 725-733.
42. Ning, Z.F., Huang, Y.J., Lin, T.X., Zhou, Y.X., Jiang, C., Xu, K.W., et al. (2009) Subpopulations of stem-like cells in side population cells from the human bladder transitional cell cancer cell line T24. J. Int. Med. Res. 37(3), 621-630.
43. Bentivegna, A., Conconi, D., Panzeri, E., Sala, E., Bovo, G., Vigano, P., et al. (2010) Biological heterogeneity of putative bladder cancer stem-like cell populations from human bladder transitional cell carcinoma samples. Cancer Sci. 101(2), 416-424.
44. Bryan, R.T., Atherfold, P.A., Yeo, Y., Jones, L.J., Harrison, R.F., Wallace, D.M., et al. (2008) Cadherin switching dictates the biology of transitional cell carcinoma of the bladder: ex vivo and in vitro studies. J. Pathol. 215(2), 184-194. (Pubitemid 351786037)
45. Van Marck, V., Stove, C., Jacobs, K., Van den Eynden, G., and Bracke, M. (2011) P-cadherin in adhesion and invasion: opposite roles in colon and bladder carcinoma. Int. J. Cancer 128(5), 1031-1044.
46. Bryan, R.T., Zeegers, M.P., James, N.D., Wallace, D.M., and Cheng, K.K. (2009) Biomarkers in bladder cancer. BJU Int. 105(5), 608-613.
47. Garcia, S.B., Park, H.S., Novelli, M., and Wright, N.A. (1999) Field cancerization, clonality, and epithelial stem cells: the spread of mutated clones in epithelial sheets. J. Pathol. 187(1), 61-81. (Pubitemid 29009836)
48. Sidransky, D., Frost, P., Von Eschenbach, A., Oyasu, R., Preisinger, A.C., and Vogelstein, B. (1992) Clonal origin bladder cancer. N. Engl. J. Med. 326(11), 737-740.
49. Majewski, T., Lee, S., Jeong, J., Yoon, D.S., Kram, A., Kim, M.S., et al. (2008) Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy. Lab. Invest. 88(7), 694-721.
50. Crawford, J.M. (2008) The origins of bladder cancer. Lab. Invest. 88(7), 686-693.
51. Stoehr, R., Krieg, R.C., Knuechel, R., Hofstaedter, F., Pilarsky, C., Zaak, D., et al. (2002) No evidence for involvement of beta-catenin and APC in urothelial carcinomas. Int. J. Oncol. 20(5), 905-911.
52. Adam, L., Zhong, M., Choi, W., Qi, W., Nicoloso, M., Arora, A., et al. (2009) miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy. Clin. Cancer Res. 15(16), 5060-5072.
53. Black, P.C. and Dinney, C.P. (2007) Bladder cancer angiogenesis and metastasis--translation from murine model to clinical trial. Cancer Metastasis Rev. 26(3-4), 623-634. (Pubitemid 350115114)
54. Black, P.C., Brown, G.A., Inamoto, T., Shrader, M., Arora, A., Siefker-Radtke, A.O., et al. (2008) Sensitivity to epidermal growth factor receptor inhibitor requires E-cadherin expression in urothelial carcinoma cells. Clin. Cancer Res. 14(5), 1478-1486.